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Research Paper

The effect of propofol on the proliferation and apoptosis of hepatocellular carcinoma cells through TGF-Β1/Smad2 signaling pathway

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Pages 4581-4592 | Received 02 Jun 2021, Accepted 08 Jul 2021, Published online: 29 Jul 2021

References

  • Zhou M, Yang L, Shao M, et al. Effects of zearalenone exposure on the TGF-β1/Smad3 signaling pathway and the expression of proliferation or apoptosis related genes of post-weaning gilts. Toxins (Basel). 2018;10(2):49.
  • Gong C, Fang J, Li G. Effects of MicroRNA-126 on cell proliferation, apoptosis and tumor angiogenesis via the down-regulating ERK signaling pathway by targeting EGFL7 in hepatocellular carcinoma. Oncotarget. 2017;8(32):52527–52542.
  • Yao X, Cui X, Wu X. Tumor suppressive role of miR-1224-5p in keloid proliferation, apoptosis and invasion via the TGF-β1/Smad3 signaling pathway. Biochem Biophys Res Commun. 2018;495(1):713–714.
  • Li Y, Dong W, Yang H. Propofol suppresses proliferation and metastasis of colorectal cancer cells by regulating miR-124-3p.1/AKT3. Biotechnol Lett. 2020;42(3):493–504.
  • Sun H, Wang Y, Zhang W. Propofol inhibits proliferation and metastasis by up-regulation of miR-495 in JEG-3 choriocarcinoma cells. Artif Cells. 2019;47(1):1738–1745.
  • Cui J, Zhao H, Ma D. Abstracts from the BJA research forum york, November 12- 13,2015. BJA. 2016;116(6):929–940.
  • Wang JW, Cheng WW, Xu T. Propofol induces apoptosis and inhibits the proliferation of rat embryonic neural stem cells via gamma-aminobutyric acid type A receptor. Genet Mol Res: GMR. 2015;14(4):14920–14928.
  • Xu YB, Jiang W, Zhao FR. Propofol suppresses invasion and induces apoptosis of osteosarcoma cell in vitro via downregulation of TGF-β1 expression. Eur Rev Med Pharmacol. 2016;20(7):1430–1435.
  • Liu C, Peng S, Li Q. RE-1 silencing transcription factor alleviates the growth-suppressive effects of propofol on mouse neuronal cells. NeuroReport. 2019;30(15):1025–1030.
  • Wang ZT, Gong HY, Zheng F. propofol suppresses proliferation and invasion of gastric cancer cells via downregulation of microRNA-221 expression. Genet Mol Res Gmr. 2015;14(3):8117–8124.
  • Shang Z, Feng H, Cui L. Propofol promotes apoptosis and suppresses the HOTAIR-mediated mTOR/p70S6K signaling pathway in melanoma cells. Oncol Lett. 2018;15(1):630–631.
  • Liu Z, Zhang J, Hong G. Propofol inhibits growth and invasion of pancreatic cancer cells through regulation of the miR-21/slug signaling pathway. Am J Transl Res. 2016;8(10):4120–4133.
  • Xu YJ, Li SY, Cheng Q. Effects of anaesthesia on proliferation, invasion and apoptosis of LoVo colon cancer cells in vitro. Anaesthesia. 2015;71(2):147–154.
  • Wang S, Liang S, Zhao X. Propofol inhibits cell proliferation and invasion in rheumatoid arthritis fibroblast-like synoviocytes via the nuclear factor-κB pathway. Am J Transl Res. 2017;9(5):2429–2430.
  • Wang ZT, Gong HY, Zheng F. Propofol suppresses proliferation and invasion of pancreatic cancer cells by upregulating MicroRNA-133a expression. Gene Mol Res Gmr. 2015;14(3):7529–7530.
  • Fan J, Zhou Q, Qin Z. Effect of propofol on MicroRNA expression in rat primary embryonic neural stem cells. BMC Anesthesiol. 2016;16(1):95–96.
  • Yu B, Gao W, Zhou H. Propofol induces apoptosis of breast cancer cells by downregulation of miR-24 signal pathway. Cancer Biomarkers. 2017;21(1–3):1–7.
  • Meng J, Xin X, Liu Z. Propofol inhibits Th2 cell differentiation by inducing apoptosis via activating GABA receptor. J Surg Res. 2016;206(2):442–450.
  • Wang JW, Cheng WW, Xu T. Propofol induces apoptosis and inhibits the proliferation of rat embryonic neural stem cells via gamma-aminobutyric acid type A receptor. Genet Mol Res. 2015;14(4):14920–14928.
  • Fang HW, Kao WY, Lin PI. Effects of polypropylene carbonate/Poly(D, l-lactic) acid/tricalcium phosphate elastic composites on improving osteoblast maturation. Ann Biomed Eng. 2015;43(8):1–11.
  • Meng J, Xin X, Liu Z. Propofol Inhibits T-helper cell type-2 differentiation by inducing apoptosis via activating gamma-aminobutyric acid receptor. J Surg Res. 2016;206(2):442–450.
  • Jiang Q, Wang Y, Shi X. Propofol inhibits neurogenesis of rat neural stem cells by upregulating MicroRNA-141-3p. Stem Cells Dev. 2017;26(3):189–190.
  • Zhu XQ, Lin CS, Guo PP. Effects of propofol on myelin basic protein expression in oligodendrocytes of sd rats at different developmental stages. J Southern Med Univ. 2017;37(12):1615–1619.
  • Bai J, Li Y, Wang YB, et al. Propofol accelerates lung cancer cells apoptosis through regulation of Rno-miR-665 and BCLXL expression. Int J Clin Exp Med. 2017;10(5):8500–8510.
  • Wang G, Tang L, Qian J. Effect of fibulin-2 on proliferation and apoptosis of gastric cancer cells by inhibiting TGF-β1/Smad4 signal pathway. Acta Med Mediterr. 2019;35(2):727–732.
  • Dong XH, Chang H, Zhu JB, et al. Effects of transforming growth factor /smad signaling pathway on liver cancer. J Yanbian Univ. 2019;42(1):69–72.