Laboratory characteristics analysis of the efficacy of levothyroxine on subclinical hypothyroidism during pregnancy: a single-center retrospective study

References

• Maraka S, Ospina NM, O’Keeffe DT, et al. Subclinical hypothyroidism in pregnancy: a systematic review and meta-analysis. Thyroid. 2016;26(4):580–590.
   PubMed Web of Science ®Google Scholar
• Li C, Shan Z, Mao J, et al. Assessment of thyroid function during first-trimester pregnancy: what is the rational upper limit of serum TSH during the first trimester in Chinese pregnant women? J Clin Endocrinol Metab. 2014;99(1):73–79.
   PubMed Web of Science ®Google Scholar
• De Groot L, Abalovich M, Alexander EK, et al. Management of thyroid dysfunction during pregnancy and postpartum: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2012;97(8):2543–2565.
   PubMed Web of Science ®Google Scholar
• Alexander EK, Pearce EN, Brent GA, et al. 2017 guidelines of the American thyroid association for the diagnosis and management of thyroid disease during pregnancy and the postpartum. Thyroid. 2017;27(3):315–389.
   PubMed Web of Science ®Google Scholar
• Parizad Nasirkandy M, Badfar G, Shohani M, et al. The relation of maternal hypothyroidism and hypothyroxinemia during pregnancy on preterm birth: an updated systematic review and meta-analysis. Int J Reprod Biomed. 2017;15:543–552.
   PubMed Web of Science ®Google Scholar
• Tong Z, Xiaowen Z, Baomin C, et al. The effect of subclinical maternal thyroid dysfunction and autoimmunity on intrauterine growth restriction: a systematic review and meta-analysis. Medicine (Baltimore). 2016;95(19):e3677.
   PubMed Web of Science ®Google Scholar
• Nelson DB, Casey BM, McIntire DD, et al. Subsequent pregnancy outcomes in women previously diagnosed with subclinical hypothyroidism. Am J Perinatol. 2014;31:77–84.
   PubMed Web of Science ®Google Scholar
• Sen A, Kushnir VA, Barad DH, et al. Endocrine autoimmune diseases and female infertility. Nat Rev Endocrinol. 2014;10(1):37–50.
   PubMed Web of Science ®Google Scholar
• Rushworth FH, Backos M, Rai R, et al. Prospective pregnancy outcome in untreated recurrent miscarriers with thyroid autoantibodies. Hum Reprod. 2000;15(7):1637–1639.
   PubMed Web of Science ®Google Scholar
• Rao M, Zeng Z, Zhao S, et al. Effect of levothyroxine supplementation on pregnancy outcomes in women with subclinical hypothyroidism and thyroid autoimmuneity undergoing in vitro fertilization/intracytoplasmic sperm injection: an updated meta-analysis of randomized controlled trials. Reprod Biol Endocrinol. 2018;16(1):92.
   PubMed Web of Science ®Google Scholar
• Abdel Rahman AH, Aly Abbassy H, Abbassy AA. Improved in vitro fertilization outcomes after treatment of subclinical hypothyroidism in infertile women. Endocr Pract. 2010;16(5):792–797.
   PubMed Web of Science ®Google Scholar
• Yamamoto JM, Benham JL, Nerenberg KA, et al. Impact of levothyroxine therapy on obstetric, neonatal and childhood outcomes in women with subclinical hypothyroidism diagnosed in pregnancy: a systematic review and meta-analysis of randomised controlled trials. BMJ Open. 2018;8(9):e022837.
   PubMed Web of Science ®Google Scholar
• ACOG. Committee opinion no. 548: weight gain during pregnancy. Obstet Gynecol. 2013;121(1):210–212.
   PubMedGoogle Scholar
• Gietka-Czernel M, Glinicki P. Subclinical hypothyroidism in pregnancy: controversies on diagnosis and treatment. Pol Arch Intern Med. 2021;131:266–275.
   PubMedGoogle Scholar
• León G, Murcia M, Rebagliato M, et al. Maternal thyroid dysfunction during gestation, preterm delivery, and birthweight. The Infancia y Medio Ambiente Cohort, Spain. Paediatr Perinat Epidemiol. 2015;29:113–122.
   PubMed Web of Science ®Google Scholar
• Maraka S, Singh Ospina NM, O’Keeffe DT, et al. Effects of levothyroxine therapy on pregnancy outcomes in women with subclinical hypothyroidism. Thyroid. 2016;26(7):980–986.
   PubMed Web of Science ®Google Scholar
• El Rafei R, Abbas HA, Charafeddine L, et al. Association of pre-pregnancy body mass index and gestational weight gain with Preterm Births and fetal size: an observational study from Lebanon. Paediatr Perinat Epidemiol. 2016;30(1):38–45.
   PubMed Web of Science ®Google Scholar
• Kominiarek MA, Peaceman AM. Gestational weight gain. Am J Obstet Gynecol. 2017;217(6):642–651.
   PubMed Web of Science ®Google Scholar
• Casey BM, Dashe JS, Spong CY, et al. Perinatal significance of isolated maternal hypothyroxinemia identified in the first half of pregnancy. Obstet Gynecol. 2007;109(5):1129–1135.
   PubMed Web of Science ®Google Scholar
• Nazarpour S, Ramezani Tehrani F, Simbar M, et al. Effects of levothyroxine on pregnant women with subclinical hypothyroidism, negative for thyroid peroxidase antibodies. J Clin Endocrinol Metab. 2018;103(3):926–935.
   PubMed Web of Science ®Google Scholar
• Khan SH, Fazal N, Ijaz A, et al. Insulin resistance and glucose levels in subjects with subclinical hypothyroidism. J Coll Physicians Surg Pak. 2017;27:329–333.
   PubMed Web of Science ®Google Scholar
• Dong X, Yao Z, Hu Y, et al. Potential harmful correlation between homocysteine and low-density lipoprotein cholesterol in patients with hypothyroidism. Medicine (Baltimore). 2016;95(29):e4291.
   PubMed Web of Science ®Google Scholar
• Ceyhan ST, Beyan C, Atay V, et al. Serum vitamin B12 and homocysteine levels in pregnant women with neural tube defect. Gynecol Endocrinol. 2010;26:578–581.
   PubMed Web of Science ®Google Scholar
• Dhobale M, Chavan P, Kulkarni A, et al. Reduced folate, increased vitamin B(12) and homocysteine concentrations in women delivering preterm. Ann Nutr Metab. 2012;61(1):7–14.
   PubMed Web of Science ®Google Scholar
• Lindblad B, Zaman S, Malik A, et al. Folate, vitamin B12, and homocysteine levels in South Asian women with growth-retarded fetuses. Acta Obstet Gynecol Scand. 2005;84:1055–1061.
   PubMed Web of Science ®Google Scholar
• Yajnik CS, Chandak GR, Joglekar C, et al. Maternal homocysteine in pregnancy and offspring birthweight: epidemiological associations and Mendelian randomization analysis. Int J Epidemiol. 2014;43:1487–1497.
   PubMed Web of Science ®Google Scholar
• Li Y, Zhang H, Jiang C, et al. Hyperhomocysteinemia promotes insulin resistance by inducing endoplasmic reticulum stress in adipose tissue. J Biol Chem. 2013;288(14):9583–9592.
   PubMed Web of Science ®Google Scholar
• Barjaktarovic M, Steegers EAP, Jaddoe VWV, et al. The association of thyroid function with maternal and neonatal homocysteine concentrations. J Clin Endocrinol Metab. 2017;102(12):4548–4556.
   PubMed Web of Science ®Google Scholar
• Serapinas D, Boreikaite E, Bartkeviciute A, et al. The importance of folate, vitamins B6 and B12 for the lowering of homocysteine concentrations for patients with recurrent pregnancy loss and MTHFR mutations. Reprod Toxicol. 2017;72:159–163.
   PubMedGoogle Scholar