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Research Paper

A circular RNA, circUSP36, accelerates endothelial cell dysfunction in atherosclerosis by adsorbing miR-637 to enhance WNT4 expression

, , , , & ORCID Icon
Pages 6759-6770 | Received 01 May 2021, Accepted 03 Aug 2021, Published online: 14 Sep 2021

References

  • Libby P, Ridker PM, Maseri A. Inflammation and atherosclerosis. Circulation. 2002;105(9):1135–1143.
  • Li Z, Xu C, Sun D. MicroRNA-488 serves as a diagnostic marker for atherosclerosis and regulates the biological behavior of vascular smooth muscle cells. Bioengineered. 2021;12(1):4092–4099.
  • Lu Y, Ballew SH, Tanaka H, et al. 2017 ACC/AHA blood pressure classification and incident peripheral artery disease: the Atherosclerosis Risk in Communities (ARIC) Study. Eur J Prev Cardiol. 2017; 271: 51–59.
  • Barquera S, Pedroza-Tobías A, Medina C, et al. Global overview of the epidemiology of atherosclerotic cardiovascular disease. Arch Med Res. 2015;46(5):328–338.
  • Benjamin EJ, et al. Heart disease and stroke statistics-2017 update: a report from the american heart association. Circulation. 2017;135(10):e146–e603.
  • Schaftenaar F, Frodermann V, Kuiper J, et al. Atherosclerosis: the interplay between lipids and immune cells. Curr Opin Lipidol. 2016;27(3):209–215.
  • Zhu Y, Xian X, Wang Z, et al. Research progress on the relationship between atherosclerosis and inflammation. Biomolecules. 2018;8(3):3.
  • Sturtzel C. Endothelial cells. Adv Exp Med Biol. 2017;1003:71–91.
  • Tang F, Yang TL. MicroRNA-126 alleviates endothelial cells injury in atherosclerosis by restoring autophagic flux via inhibiting of PI3K/Akt/mTOR pathway. Biochem Biophys Res Commun. 2018;495(1):1482–1489.
  • Cai T, et al. LncRNA TNK2-AS1 regulated ox-LDL-stimulated HASMC proliferation and migration via modulating VEGFA and FGF1 expression by sponging miR-150-5p. 2019;23(11):7289–7298.
  • Qin X, Guo J. MicroRNA-328-3p protects vascular endothelial cells against oxidized low-density lipoprotein induced injury via targeting forkhead box protein O4 (FOXO4) in atherosclerosis. Med Sci Monit. 2020;26:e921877.
  • Hang L, et al. Ox-LDL causes endothelial cell injury Through ASK1/NLRP3-mediated inflammasome activation via endoplasmic reticulum stress. 2020;14:731–744.
  • Sun JJ, Yin X-W, Liu -H-H, et al. Rapamycin inhibits ox-LDL-induced inflammation in human endothelial cells in vitro by inhibiting the mTORC2/PKC/c-Fos pathway. Acta Pharmacol Sin. 2018;39(3):336–344.
  • Yin S, et al. MicroRNA 155 promotes ox LDL induced autophagy in human umbilical vein endothelial cells by targeting the PI3K/Akt/mTOR pathway. Mol Med Rep. 2018;18(3):2798–2806.
  • Zeng W, Guo M, Yao L, et al. Circular RNA hsa_circ_0033144 (CircBCL11B) regulates oral squamous cell carcinoma progression via the miR-579/LASP1 axis. Bioengineered. 2021;12(1):111–4122.
  • Greene J, Baird A-M, Brady L, et al. Circular RNAs: biogenesis, function and role in human diseases. Front Mol Biosci. 2017;4:38.
  • Holdt LM, Kohlmaier A, Teupser D. Molecular roles and function of circular RNAs in eukaryotic cells. Cell Mol Life Sci. 2018;75(6):1071–1098.
  • Zhang CC, Li Y, Feng XZ, et al. Circular RNA circ_0001287 inhibits the proliferation, metastasis, and radiosensitivity of non-small cell lung cancer cells by sponging microRNA miR-21 and up-regulating phosphatase and tensin homolog expression. Bioengineered. 2021;12(1):414–425.
  • Wei MY, Lv RR, Teng Z. Circular RNA circHIPK3 as a novel circRNA regulator of autophagy and endothelial cell dysfunction in atherosclerosis. Eur Rev Med Pharmacol Sci. 2020;24(24):12849–12858.
  • Yang L, Yang F, Zhao H, et al. Circular RNA circCHFR facilitates the proliferation and migration of vascular smooth muscle via miR-370/FOXO1/Cyclin D1 Pathway. Mol Ther Nucleic Acids. 2019;16:434–441.
  • Wei Z, Ran H, Yang C. CircRSF1 contributes to endothelial cell growth, migration and tube formation under ox-LDL stress through regulating miR-758/CCND2 axis. Life Sci. 2020;259:118241.
  • Li CY, Ma L, Yu B. Circular RNA hsa_circ_0003575 regulates oxLDL induced vascular endothelial cells proliferation and angiogenesis. Biomed Pharmacother. 2017;95:1514–1519.
  • Singh KK, Matkar PN, Pan Y, et al. Endothelial long non-coding RNAs regulated by oxidized LDL. Mol Cell Biochem. 2017;431(1–2):139–149.
  • Zhao W, Su J, Wang N, et al. Expression profiling and bioinformatics analysis of CircRNA in mice brain infected with rabies virus. Int J Mol Sci. 2021 Jun 18;22(12):6537. PMID: 34207166; PMCID: PMC8234020.
  • Zheng Q, Zhang J, Zhang T, et al. Hsa_circ_0000520 overexpression increases CDK2 expression via miR-1296 to facilitate cervical cancer cell proliferation. J Transl Med. 2021 Jul 20;19(1):314. PMID: 34284793; PMCID: PMC8290540.
  • Zhang D, Fang C, Li H, et al. Long ncRNA MALAT1 promotes cell proliferation, migration, and invasion in prostate cancer via sponging miR-145. Transl Androl Urol. 2021 Jun;10(6):2307–2319. PMID: 34295718; PMCID: PMC8261405
  • Tong J, Liu H, Yao W, et al. Down-regulation of circRNA_0000143 regulates miR-142-3p/GRα axis to facilitate the progression of T-ALL. Cancer Sci. 2021 Jul 26. DOI:10.1111/cas.15082. Epub ahead of print. PMID: 34309993.
  • Rossi A, Orecchioni S, Falvo P, et al. Dual targeting of the DNA damage response pathway and BCL-2 in diffuse large B-cell lymphoma. Leukemia. 2021 Jul 24. 10.1038/s41375-021-01347-6. Epub ahead of print. PMID: 34304248.
  • Bian W, Jing X, Yang Z, et al. Downregulation of LncRNA NORAD promotes Ox-LDL-induced vascular endothelial cell injury and atherosclerosis. Aging (Albany NY). 2020;12(7):6385–6400.
  • Navarro E, et al. Unveiling ncRNA regulatory axes in atherosclerosis progression. 2020;9(1):5.
  • Huang Z, Feng Y. Exosomes derived from hypoxic colorectal cancer cells promote angiogenesis through Wnt4-induced β-catenin signaling in endothelial cells. Oncol Res. 2017;25(5):651–661.
  • Shan H, Guo D, Zhang S, et al. SNHG6 modulates oxidized low-density lipoprotein-induced endothelial cells injury through miR-135a-5p/ROCK in atherosclerosis. Cell Biosci. 2020;10(1):4.
  • Khyzha N, Alizada A, Wilson MD, et al. Epigenetics of atherosclerosis: emerging mechanisms and methods. Trends Mol Med. 2017;23(4):332–347.
  • Chen L, Fang Z, Wang X, et al. G protein-coupled receptor 39 activation alleviates oxidized low-density lipoprotein-induced macrophage inflammatory response, lipid accumulation and apoptosis by inducing A20 expression. Bioengineered. 2021;12(1):4070–4080.
  • Cui Y, Li C, Zeng C, et al. Tongmai Yangxin pills anti-oxidative stress alleviates cisplatin-induced cardiotoxicity: network pharmacology analysis and experimental evidence. Biomed Pharmacother. 2018;108:1081–1089.
  • Wang TM, Chen K-C, Hsu P-Y, et al. microRNA let-7g suppresses PDGF-induced conversion of vascular smooth muscle cell into the synthetic phenotype. J Cell Mol Med. 2017;21(12):3592–3601.
  • Chyu KY, Dimayuga PC, Shah PK. Immunogenetics of Atherosclerosis—Link between Lipids, Immunity, and Genes. Curr Atheroscler Rep. 2020;22(10):53.
  • Kattoor AJ, Goel A. LOX-1: regulation, signaling and its role in atherosclerosis. 8(7):2019.
  • Cao Q, Guo Z, Du S, et al. Circular RNAs in the pathogenesis of atherosclerosis. Life Sci. 2020;255:117837.
  • Altesha MA, et al. Circular RNA in cardiovascular disease. 2019;234(5):5588–5600.
  • Ding S, et al. Circular RNAs in vascular functions and diseases. Adv Exp Med Biol. 2018;1087:287–297.
  • Wang L, Shen C, Wang Y, et al. Identification of circular RNA Hsa_circ_0001879 and Hsa_circ_0004104 as novel biomarkers for coronary artery disease. Atherosclerosis. 2019;286:88–96.
  • Zeng Z, Xia L, Fan S, et al. Circular RNA CircMAP3K5 Acts as a MicroRNA-22-3p sponge to promote resolution of intimal hyperplasia via TET2-mediated smooth muscle cell differentiation. Circulation. 2021;143(4):354–371.
  • Liu H, Ma X, Mao Z, et al. Circular RNA has_circ_0003204 inhibits oxLDL-induced vascular endothelial cell proliferation and angiogenesis. Cell Signal. 2020;70:109595.
  • Zhang S, Song G, Yuan J, et al. Circular RNA circ_0003204 inhibits proliferation, migration and tube formation of endothelial cell in atherosclerosis via miR-370-3p/TGFβR2/phosph-SMAD3 axis. J Biomed Sci. 2020;27(1):11.
  • Miao J, Wang B, Shao R, et al. CircUSP36 knockdown alleviates oxidized low‑density lipoprotein‑induced cell injury and inflammatory responses in human umbilical vein endothelial cells via the miR‑20a‑5p/ROCK2 axis. Int J Mol Med. 2021;47(4):1.
  • Peng K, et al. Oxidized low-density lipoprotein accelerates the injury of endothelial cells via circ-USP36/miR-98-5p/VCAM1 axis. 2021;73(1):177–187.
  • Zhang F, et al. Comprehensive analysis of circRNA expression pattern and circRNA-miRNA-mRNA network in the pathogenesis of atherosclerosis in rabbits. Aging (Albany NY). 2018;10(9):2266–2283.
  • Wang L, Zheng Z, Feng X, et al. circRNA/lncRNA-miRNA-mRNA network in oxidized, low-density, lipoprotein-induced foam cells. DNA Cell Biol. 2019;38(12):1499–1511.
  • Zhong Y, Du Y, Yang X, et al. Circular RNAs function as ceRNAs to regulate and control human cancer progression. Mol Cancer. 2018;17(1):79.
  • Deng G, Mou T, He J, et al. Circular RNA circRHOBTB3 acts as a sponge for miR-654-3p inhibiting gastric cancer growth. J Exp Clin Cancer Res. 2020;39(1):1.
  • Yang N, Dong B, Song Y, et al. Downregulation of miR-637 promotes vascular smooth muscle cell proliferation and migration via regulation of insulin-like growth factor-2. Cell Mol Biol Lett. 2020;25(1):30.
  • Brown BA, et al. Carotid artery ligation induced intimal thickening and proliferation is unaffected by ageing. 2018;12(3):529–537.
  • Tsaousi A, et al. Wnt4/β-catenin signaling induces VSMC proliferation and is associated with intimal thickening. Circ Res. 2011;108(4):88–96.