Remifentanil pretreatment ameliorates H/R-induced cardiac microvascular endothelial cell dysfunction by regulating the PI3K/Akt/HIF-1α signaling pathway

References

• Shao C, Wang J, Tian J, et al. Coronary artery disease: from mechanism to clinical practice. Adv Exp Med Biol. 2020;1177:1–36. PubMed PMID: 32246442.
   PubMed Web of Science ®Google Scholar
• Matta A, Bouisset F, Lhermusier T, et al. Coronary artery spasm: new insights. J Interv Cardiol. 2020;2020:5894586. PubMed PMID: 32508542; PubMed Central PMCID: PMCPMC7245659.
   PubMed Web of Science ®Google Scholar
• Pagliaro BR, Cannata F, Stefanini GG, et al. Myocardial ischemia and coronary disease in heart failure. Heart Fail Rev. 2020;25(1):53–65. PubMed PMID: 31332663.
   PubMed Web of Science ®Google Scholar
• Jia S, Liu Y, Yuan J. Evidence in guidelines for treatment of coronary artery disease. Adv Exp Med Biol. 2020;1177:37–73. PubMed PMID: 32246443.
   PubMed Web of Science ®Google Scholar
• Binder A, Ali A, Chawla R, et al. Myocardial protection from ischemia-reperfusion injury post coronary revascularization. Expert Rev Cardiovasc Ther. 2015;13(9):1045–1057. PubMed PMID: 26202544.
   PubMed Web of Science ®Google Scholar
• Du J, Li Y, Zhao W. Autophagy and Myocardial Ischemia. Adv Exp Med Biol. 2020;1207:217–222. PubMed PMID: 32671750.
   PubMed Web of Science ®Google Scholar
• Shi B, Ma M, Zheng Y, et al. mTOR and beclin1: two key autophagy-related molecules and their roles in myocardial ischemia/reperfusion injury. J Cell Physiol. 2019;234(8):12562–12568. PubMed PMID: 30618070.
   PubMed Web of Science ®Google Scholar
• Wang J, Toan S, Zhou H. New insights into the role of mitochondria in cardiac microvascular ischemia/reperfusion injury. Angiogenesis. 2020;23(3):299–314. PubMed PMID: 32246225.
   PubMed Web of Science ®Google Scholar
• Gao XM, Su Y, Moore S, et al. Relaxin mitigates microvascular damage and inflammation following cardiac ischemia-reperfusion. Basic Res Cardiol. 2019;114(4):30. PubMed PMID: 31218471.
   PubMed Web of Science ®Google Scholar
• Rios-Navarro C, Marcos-Garces V, Bayes-Genis A, et al. Microvascular obstruction in st-segment elevation myocardial infarction: looking back to move forward. focus on CMR. J Clin Med. 2019;8(11):1805. PubMed PMID: 31661823; PubMed Central PMCID: PMCPMC6912395.
   PubMed Web of Science ®Google Scholar
• Nowoczyn M, Marie N, Coulbault L, et al. Remifentanil produces cross-desensitization and tolerance with morphine on the mu-opioid receptor. Neuropharmacology. 2013;73:368–379. PubMed PMID: 23792280.
   PubMed Web of Science ®Google Scholar
• Greco M, Landoni G, Biondi-Zoccai G, et al. Remifentanil in cardiac surgery: a meta-analysis of randomized controlled trials. J Cardiothorac Vasc Anesth. 2012;26(1):110–116. PubMed PMID: 21820920.
   PubMed Web of Science ®Google Scholar
• Subramaniam K, Sciortino C, Ruppert K, et al. Remifentanil and perioperative glycaemic response in cardiac surgery: an open-label randomised trial. Br J Anaesth. 2020;124(6):684–692. PubMed PMID: 32247539.
   PubMed Web of Science ®Google Scholar
• Lei S, Su W, Xia ZY, et al. Hyperglycemia-induced oxidative stress abrogates remifentanil preconditioning-mediated cardioprotection in diabetic rats by impairing caveolin-3-Modulated PI3K/Akt and JAK2/STAT3 signaling. Oxid Med Cell Longev. 2019;2019:9836302. PubMed PMID: 31583053; PubMed Central PMCID: PMCPMC6748204.
   PubMed Web of Science ®Google Scholar
• Gao F, Wu H, Wang R, et al. MicroRNA-485-5p suppresses the proliferation, migration and invasion of small cell lung cancer cells by targeting flotillin-2. Bioengineered. 2019;10(1):1–12. PubMed PMID: 30836864; PubMed Central PMCID: PMCPMC6527069.
   PubMed Web of Science ®Google Scholar
• Li J, Guo Y, Duan L, et al. AKR1B10 promotes breast cancer cell migration and invasion via activation of ERK signaling. Oncotarget. 2017;8(20):33694–33703. PubMed PMID: 28402270; PubMed Central PMCID: PMCPMC5464903.
   PubMedGoogle Scholar
• Shang J, Gao ZY, Zhang LY, et al. Over-expression of JAZF1 promotes cardiac microvascular endothelial cell proliferation and angiogenesis via activation of the Akt signaling pathway in rats with myocardial ischemia-reperfusion. Cell Cycle. 2019;18(14):1619–1634. PubMed PMID: 31177938; PubMed Central PMCID: PMCPMC6619954.
   PubMed Web of Science ®Google Scholar
• Li Z, Yin M, Zhang H, et al. BMX represses thrombin-PAR1-mediated endothelial permeability and vascular leakage during early sepsis. Circ Res. 2020;126(4):471–485. PubMed PMID: 31910739; PubMed Central PMCID: PMCPMC7035171.
   PubMed Web of Science ®Google Scholar
• Ambrose JA. Myocardial ischemia and infarction. J Am Coll Cardiol. 2006;47(11Suppl):D13–7. PubMed PMID: 16750715.
   PubMedGoogle Scholar
• Zhao M, Klipstein-Grobusch K, Wang X, et al. Prevalence of cardiovascular medication on secondary prevention after myocardial infarction in China between 1995-2015: a systematic review and meta-analysis. PLoS One. 2017;12(4):e0175947. PubMed PMID: 28426793; PubMed Central PMCID: PMCPMC5398555.
   PubMed Web of Science ®Google Scholar
• Vaccarino V, Sullivan S, Hammadah M, et al. mental stress-induced-myocardial ischemia in young patients with recent myocardial infarction: sex differences and mechanisms. Circulation. 2018;137(8):794–805. PubMed PMID: 29459465; PubMed Central PMCID: PMCPMC5822741.
   PubMed Web of Science ®Google Scholar
• Safdar B, Spatz ES, Dreyer RP, et al. Presentation, Clinical Profile, and Prognosis of Young Patients With Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): results From the VIRGO Study. J Am Heart Assoc. 2018;7(13). PubMed PMID: 29954744; PubMed Central PMCID: PMCPMC6064896. 10.1161/JAHA.118.009174
   PubMed Web of Science ®Google Scholar
• Lindner JR. Microvascular Impairment After Myocardial Infarction: it Is Not Just About Obstruction. Circ Cardiovasc Imaging. 2020;13(6):e011083. PubMed PMID: 32527158; PubMed Central PMCID: PMCPMC7491571.
   PubMed Web of Science ®Google Scholar
• Cohen J, Royston D. Remifentanil. Curr Opin Crit Care. 2001;7(4):227–231. PubMed PMID: 11571418.
   PubMedGoogle Scholar
• Irwin MG, Wong GT. Remifentanil and opioid-induced cardioprotection. J Cardiothorac Vasc Anesth. 2015;29(Suppl 1):S23–6. PubMed PMID: 26025042.
   PubMedGoogle Scholar
• Tanaka K, Kersten JR, Riess ML. Opioid-induced cardioprotection. Curr Pharm Des. 2014;20(36):5696–5705. PubMed PMID: 24502571; PubMed Central PMCID: PMCPMC4216587.
   PubMed Web of Science ®Google Scholar
• Kim JM, Jang YH, Kim J. Morphine and remifentanil-induced cardioprotection: its experimental and clinical outcomes. Korean J Anesthesiol. 2011;61(5):358–366. PubMed PMID: 22148082; PubMed Central PMCID: PMCPMC3229012.
   PubMedGoogle Scholar
• Lewinska A, Adamczyk-Grochala J, Bloniarz D, et al. Remifentanil preconditioning protects against hypoxia-induced senescence and necroptosis in human cardiac myocytes in vitro. Aging (Albany NY). 2020;12(14):13924–13938. PubMed PMID: 32584786; PubMed Central PMCID: PMCPMC7425462.
   PubMedGoogle Scholar
• Zhou Q, Song J, Wang Y, et al. Remifentanil attenuates cardiac dysfunction, lipid peroxidation and immune disorder in rats with isoproterenol-induced myocardial injury via JNK/NF-KB p65 inhibition. Ann Transl Med. 2020;8(8):551. PubMed PMID: 32411774; PubMed Central PMCID: PMCPMC7214888.
   PubMed Web of Science ®Google Scholar
• Zuo Y, Zhang J, Cheng X, et al. Enhanced autophagic flux contributes to cardioprotection of remifentanil postconditioning after hypoxia/reoxygenation injury in H9c2 cardiomyocytes. Biochem Biophys Res Commun. 2019;514(3):953–959. PubMed PMID: 31092327.
   PubMed Web of Science ®Google Scholar
• Shi Y, Vanhoutte PM. Macro- and microvascular endothelial dysfunction in diabetes. J Diabetes. 2017;9(5):434–449. PubMed PMID: 28044409.
   PubMed Web of Science ®Google Scholar
• Yu H, Kalogeris T, Korthuis RJ. Reactive species-induced microvascular dysfunction in ischemia/reperfusion. Free Radic Biol Med. 2019;135:182–197. PubMed PMID: 30849489; PubMed Central PMCID: PMCPMC6503659.
   PubMed Web of Science ®Google Scholar
• Zhu T, Yao Q, Wang W, et al. iNOS induces vascular endothelial cell migration and apoptosis via autophagy in ischemia/reperfusion injury. Cell Physiol Biochem. 2016;38(4):1575–1588. PubMed PMID: 27082814.
   PubMed Web of Science ®Google Scholar
• Filep JG, Sirois MG, Foldes-Filep E, et al. Enhancement by endothelin-1 of microvascular permeability via the activation of ETA receptors. Br J Pharmacol. 1993;109(3):880–886. PubMed PMID: 8358577; PubMed Central PMCID: PMCPMC2175619.
   PubMed Web of Science ®Google Scholar
• Tolins JP, Shultz PJ, Raij L. Role of endothelium-derived relaxing factor in regulation of vascular tone and remodeling. Update on humoral regulation of vascular tone. Hypertension. 1991;17(6 Pt 2):909–916. PubMed PMID: 2045172.
   PubMed Web of Science ®Google Scholar
• Tornavaca O, Chia M, Dufton N, et al. ZO-1 controls endothelial adherens junctions, cell-cell tension, angiogenesis, and barrier formation. J Cell Biol. 2015;208(6):821–838. PubMed PMID: 25753039; PubMed Central PMCID: PMCPMC4362456.
   PubMed Web of Science ®Google Scholar
• Jiao H, Wang Z, Liu Y, et al. Specific role of tight junction proteins claudin-5, occludin, and ZO-1 of the blood-brain barrier in a focal cerebral ischemic insult. J Mol Neurosci. 2011;44(2):130–139. PubMed PMID: 21318404.
   PubMed Web of Science ®Google Scholar
• Giannotta M, Trani M, Dejana E. VE-cadherin and endothelial adherens junctions: active guardians of vascular integrity. Dev Cell. 2013;26(5):441–454. PubMed PMID: 24044891.
   PubMed Web of Science ®Google Scholar
• Ke H, Mou X, Xia Q. Remifentanil repairs cartilage damage and reduces the degradation of cartilage matrix in post-traumatic osteoarthritis, and inhibits IL-1beta-induced apoptosis of articular chondrocytes via inhibition of PI3K/AKT/NF-kappaB phosphorylation. Ann Transl Med. 2020;8(22):1487. PubMed PMID: 33313232; PubMed Central PMCID: PMCPMC7729373.
   PubMed Web of Science ®Google Scholar
• Xie W, Zhou P, Qu M, et al. Ginsenoside re attenuates high glucose-induced RF/6A injury via regulating PI3K/AKT inhibited HIF-1alpha/VEGF signaling pathway. Front Pharmacol. 2020;11:695. PubMed PMID: 32528282; PubMed Central PMCID: PMCPMC7253708.
   PubMed Web of Science ®Google Scholar
• Liang S, Ren K, Li B, et al. LncRNA SNHG1 alleviates hypoxia-reoxygenation-induced vascular endothelial cell injury as a competing endogenous RNA through the HIF-1alpha/VEGF signal pathway. Mol Cell Biochem. 2020;465(1–2):1–11. PubMed PMID: 31792649.
   PubMed Web of Science ®Google Scholar