1,652
Views
11
CrossRef citations to date
0
Altmetric
Research Paper

RNA binding protein serine/arginine splicing factor 1 promotes the proliferation, migration and invasion of hepatocellular carcinoma by interacting with RecQ protein-like 4 mRNA

, , , &
Pages 6144-6154 | Received 19 Jul 2021, Accepted 21 Aug 2021, Published online: 04 Sep 2021

References

  • Sia D, Villanueva A, Friedman S, et al. Liver cancer cell of origin, molecular class, and effects on patient prognosis. Gastroenterology. 2017;152(4):745–761.
  • Siegel RL. Miller KD and Jemal A: cancer statistics, 2019. CA Cancer J Clin. 2019;69(1):7–34.
  • Hartke J. Johnson M and Ghabril M: the diagnosis and treatment of hepatocellular carcinoma. Semin Diagn Pathol. 2017;34(2):153–159.
  • Zhang S, Yue M, Shu R, et al. Recent advances in the management of hepatocellular carcinoma. J BUON. 2016;21:307–311.
  • Chi Z, Nie L, Peng Z, et al. RecQL4 cytoplasmic localization: implications in mitochondrial DNA oxidative damage repair. Int J Biochem Cell Biol. 2012;44(11):1942–1951.
  • Singh D, Popuri V, Kulikowicz T, et al. The human RecQ helicases BLM and RECQL4 cooperate to preserve genome stability. Nucleic Acids Res. 2012;40(14):6632–6648.
  • Guo L, Li Y, Zhao C, et al. RECQL4, Negatively regulated by miR-10a-5p, facilitates cell proliferation and invasion via MAFB in ovarian cancer. Front Oncol. 2020;10:524128.
  • Chen H, Yuan K, Wang X, et al. Overexpression of RECQL4 is associated with poor prognosis in patients with gastric cancer. Oncol Lett. 2018;16:5419–5425.
  • Arora A, Agarwal D, Abdel-Fatah T, et al. RECQL4 helicase has oncogenic potential in sporadic breast cancers. J Pathol. 2016;238(4):495–501.
  • Li J, Jin J, Liao M, et al. Upregulation of RECQL4 expression predicts poor prognosis in hepatocellular carcinoma. Oncol Lett. 2018;15:4248–4254.
  • Hentze M, Castello A, Schwarzl T, et al. A brave new world of RNA-binding proteins. Nat Rev Mol Cell Biol. 2018;19(5):327–341.
  • Audic Y, Hartley R. Post-transcriptional regulation in cancer. Biol Cell. 2004;96(7):479–498.
  • Xue J, Xia T, Liang X, et al. RNA-binding protein RNPC1: acting as a tumor suppressor in breast cancer. BMC Cancer. 2014;14(1):322.
  • Anczuków O, Rosenberg A, Akerman M, et al. The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation. Nat Struct Mol Biol. 2012;19(2):220–228.
  • Das R, Yu J, Zhang Z, et al. SR proteins function in coupling RNAP II transcription to pre-mRNA splicing. Mol Cell. 2007;26(6):867–881.
  • Zhang Z, Krainer A. Involvement of SR proteins in mRNA surveillance. Mol Cell. 2004;16(4):597–607.
  • Martínez-Terroba E, Ezponda T, Bértolo C, et al. The oncogenic RNA-binding protein SRSF1 regulates LIG1 in non-small cell lung cancer. Lab Invest. 2018;98(12):1562–1574.
  • Sheng J, Zhao Q, Zhao J, et al. SRSF1 modulates PTPMT1 alternative splicing to regulate lung cancer cell radioresistance. EBioMedicine. 2018;38:113–126.
  • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001;25(4):402–408.
  • Siegel RL. Miller KD and Jemal A: cancer statistics, 2018. CA Cancer J Clin. 2018;68(7–30):2018.
  • Sherman M. Recurrence of hepatocellular carcinoma. N Engl J Med. 2008;359(19):2045–2047.
  • Huang C, Zhuang W, Feng H, et al. Analysis of therapeutic effectiveness and prognostic factor on argon-helium cryoablation combined with transcatheter arterial chemoembolization for the treatment of advanced hepatocellular carcinoma. J Cancer Res Ther. 2016;12(7):C148–C152.
  • Zhang L, Wang Y, Sun J, et al. LINC00205 promotes proliferation, migration and invasion of HCC cells by targeting miR-122-5p. Pathol Res Pract. 2019;215(9):152515.
  • Jin H, Wang C, Jin G, et al. Regulator of calcineurin 1 gene isoform 4, down-regulated in hepatocellular carcinoma, prevents proliferation, migration, and invasive activity of cancer cells and metastasis of orthotopic tumors by inhibiting nuclear translocation of NFAT1. Gastroenterology. 2017;153(3):799–811.e733.
  • Yoshida GJ. Emerging role of epithelial-mesenchymal transition in hepatic cancer. J Exp Clin Cancer Res. 2016;35: 141.
  • van Zijl F, Zulehner G, Petz M, et al. Epithelial-mesenchymal transition in hepatocellular carcinoma. Future Oncol. 2009;5(8):1169–1179.
  • Jiang H, Zhou Z, Jin S, et al. PRMT9 promotes hepatocellular carcinoma invasion and metastasis via activating PI 3K/Akt/GSK −3β/Snail signaling. Cancer Sci. 2018;109(5):1414–1427.
  • Croteau DL, Rossi ML, Canugovi C, et al. RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity. Aging Cell. 2012;11(3):456–466.
  • Croteau DL, Singh DK, Hoh Ferrarelli L. Lu H and Bohr VA: RECQL4 in genomic instability and aging. Trends Genet. 2012;28(12):624–631.
  • Król S, Kaczmarczyk A, Wojnicki K, et al. Aberrantly Expressed RECQL4 Helicase Supports Proliferation and Drug Resistance of Human Glioma Cells and Glioma Stem Cells. Cancers (Basel). 2020; 12.
  • Su Y, Meador J, Calaf G, et al. Human RecQL4 helicase plays critical roles in prostate carcinogenesis. Cancer Res. 2010;70(22):9207–9217.
  • Lyu G, Su P, Hao X, et al. RECQL4 regulates DNA damage response and redox homeostasis in esophageal cancer. Cancer Biol Med. 2021;18(1):120–138.
  • Pereira B, Billaud M, Almeida R. RNA-Binding Proteins in Cancer: old Players and New Actors. Trends Cancer. 2017;3(7):506–528.
  • Dang H, Takai A, Forgues M, et al. Oncogenic Activation of the RNA Binding Protein NELFE and MYC Signaling in Hepatocellular Carcinoma. Cancer Cell. 2017;32(1):101–114.e108.
  • Michlewski G. Sanford JR and Caceres JF. The splicing factor SF2/ASF regulates translation initiation by enhancing phosphorylation of 4E-BP1. Mol Cell. 2008;30(2):179–189.
  • Lemaire R, Prasad J, Kashima T, et al. Stability of a PKCI-1-related mRNA is controlled by the splicing factor ASF/SF2: a novel function for SR proteins. Genes Dev. 2002;16(5):594–607.
  • Malakar P, Shilo A, Mogilevsky A, et al. Long noncoding RNA MALAT1 promotes hepatocellular carcinoma development by SRSF1 upregulation and mTOR anctivation. Cancer Res. 2017;77(5):1155–1167.
  • Lei S, Zhang B, Huang L, et al. SRSF1 promotes the inclusion of exon 3 of SRA1 and the invasion of hepatocellular carcinoma cells by interacting with exon 3 of SRA1pre-mRNA. Cell Death Discov. 2021;7(1):117.