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Bioengineered Volume 12, 2021 - Issue 1
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Research Paper

Astragaloside IV attenuates hypoxia/reoxygenation injury-induced apoptosis of type II alveolar epithelial cells through miR-21-5p

Hang Lia Department of Cardiothoracic Surgery, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China;b Department of Cardiothoracic Surgery, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, Jiangsu Province, ChinaView further author information
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Chang Yaoc Department of Breast Surgery, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, ChinaCorrespondence[email protected] [email protected]
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Kaihu Shia Department of Cardiothoracic Surgery, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China;b Department of Cardiothoracic Surgery, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, Jiangsu Province, ChinaView further author information
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Yang Zhaoa Department of Cardiothoracic Surgery, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China;b Department of Cardiothoracic Surgery, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, Jiangsu Province, ChinaView further author information
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Jin Dua Department of Cardiothoracic Surgery, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China;b Department of Cardiothoracic Surgery, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, Jiangsu Province, ChinaView further author information
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Dinghui Hua Department of Cardiothoracic Surgery, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China;b Department of Cardiothoracic Surgery, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, Jiangsu Province, ChinaView further author information
&
Zuntao Liua Department of Cardiothoracic Surgery, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China;b Department of Cardiothoracic Surgery, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, Jiangsu Province, ChinaView further author information
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Pages 7747-7754 | Received 15 Aug 2021, Accepted 15 Sep 2021, Published online: 07 Oct 2021

References

  • Zhai C, Lv J, Wang K, et al. HSP70 silencing aggravates apoptosis induced by hypoxia/reoxygenation in vitro. Exp Ther Med. 2019;18(2):1013–1020.
  • Ruaro B, Salton F, Braga L, et al. The history and mystery of alveolar epithelial type II cells: focus on their physiologic and pathologic role in lung. Int J Mol Sci. 2021 Mar 4;22(5):2566.
  • Liang S, Ren K, Li B, et al. LncRNA SNHG1 alleviates hypoxia-reoxygenation-induced vascular endothelial cell injury as a competing endogenous RNA through the HIF-1α/VEGF signal pathway. Mol Cell Biochem. 2020;465(1):1–11.
  • Wang J, Lu L, Chen S, et al. PERK overexpression-mediated Nrf2/HO-1 pathway alleviates hypoxia/reoxygenation-induced injury in neonatal murine cardiomyocytes via improving endoplasmic reticulum stress. Biomed Res Int. 2020;2020:6458060.
  • Ying Y, Sun CB, Zhang SQ, et al. Induction of autophagy via the TLR4/NF-κB signaling pathway by astragaloside IV contributes to the amelioration of inflammation in RAW264. 7 cells. Biomed Pharmacother. 2021;137:111271.
  • Zhang W, Xu L, Chen M, et al. [Effect of overexpression of microRNA-21-5p on early apoptosis of type II alveolar epithelial cells in rats with hyperoxic acute lung injury]. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2019;31(8):978–982.
  • Xu Z, Xie X, Tian J, et al. Down-regulation of mir-21 alleviates lung injury induced by burns through activating silent mating type information regulation 2 homolog 1 (SIRT1)-protein kinase B (AKT)-nuclear factor κB (NF-κB) pathway. J Biomater Tissue Eng. 2020;10(4):576–581.
  • Qin S, Wang H, Liu G, et al. miR‑21‑5p ameliorates hyperoxic acute lung injury and decreases apoptosis of AEC II cells via PTEN/AKT signaling in rats. Mol Med Rep. 2019;20(6):4953–4962.
  • Shi L, He Y, Bai B, et al. [Effects of microRNA-21 inhibitor on apoptosis of type II alveolar epithelial cells in rats with hyperoxia-induced acute lung injury]. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2017;29(3):244–248.
  • Farivar AS, Woolley SM, Fraga CH, et al. Proinflammatory response of alveolar type II pneumocytes to in vitro hypoxia and reoxygenation. Am J Transplant. 2004;4(3):346–351.
  • Zhang S, Zhang F, Feng L. The inhibition of HeLa cells proliferation through SPARCL1 mediated by SPP1[J]. Cytotechnology. 2021;73:71–78.
  • Hao TT, Liao R, Lei DL, et al. Inhibition of B7-H4 promotes hepatocellular carcinoma cell apoptosis and autophagy through the PI3K signaling pathway[J]. Int Immunopharmacol. 2020;88:106889.
  • Yang J, Liu J, Sheng M, et al. Programmed cell death protein 1 promotes hepatitis B virus transmission through the regulation of ERK1/2-mediated trophoblasts differentiation[J]. Arch Gynecol Obstet. 2020;301(2):551–558.
  • Van Lune H, Bruggeman JJ, inventors; PerkinElmer Life, Analytical Sciences BV, assignee. Luciferase detection assay system. United States patent US 7,425,422. 2008 Sep 16.
  • Zhang Y, Yu XW, Yu HC, et al. Mechanism of astragaloside regulating miR-21 gene inhibiting renal carcinoma cell proliferation and inducing apoptosis. J Mod Oncol. 2020;28(18):3145–3150.
  • Cheng ZQ, Han JY, Sun P, et al. Edaravone attenuates paraquat-induced lung injury by inhibiting oxidative stress in human type II alveolar epithelial cells. World J Emerg Med. 2012;3(1):55–59.
  • Zheng S, Yang J, Hu X, et al. Vitamin D attenuates lung injury via stimulating epithelial repair, reducing epithelial cell apoptosis and inhibits TGF-β induced epithelial to mesenchymal transition. Biochem Pharmacol. 2020;177:113955.
  • Yazicioglu T, Mühlfeld C, Autilio C, et al. Aging impairs alveolar epithelial type II cell function in acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2020;319(5):L755–69.
  • Yu Z, Wang T, Zhang L, et al. WISP1 and TLR4 on macrophages contribute to ventilator-induced lung injury. Inflammation. 2020;43(2):425–432.

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