The long non-coding RNA NNT-AS1 promotes clear cell renal cell carcinoma progression via regulation of the miR-137/ Y-box binding protein 1 axis

References

• Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68:394–424.
   PubMed Web of Science ®Google Scholar
• Jonasch E, Walker CL, Rathmell WK. Clear cell renal cell carcinoma ontogeny and mechanisms of lethality. Nat Rev Nephrol. 2021;17:245–261.
   PubMed Web of Science ®Google Scholar
• Hsieh JJ, Purdue MP, Signoretti S, et al. Renal cell carcinoma. Nature Reviews Disease Primers. 2017;3(1):17009.
   PubMed Web of Science ®Google Scholar
• Chen F, Zhang Y, Şenbabaoğlu Y, et al. Multilevel genomics-based taxonomy of renal cell carcinoma. Cell Rep. 2016;14(10):2476–2489.
   PubMed Web of Science ®Google Scholar
• Linehan WM, Ricketts CJ. The cancer genome atlas of renal cell carcinoma: findings and clinical implications. Nat Rev Urol. 2019;16(9):539–552.
   PubMed Web of Science ®Google Scholar
• Qian X, Zhao J, Yeung PY, et al. Revealing lncRNA structures and interactions by sequencing-based approaches. Trends Biochem Sci. 2019;44(1):33–52.
   PubMed Web of Science ®Google Scholar
• St Laurent G, Wahlestedt C, Kapranov P. The landscape of long noncoding RNA classification. Trends Genet.2015;31(5):239–251.
   Google Scholar
• Zhao Z, Sun W, Guo Z, et al. Mechanisms of lncRNA/microRNA interactions in angiogenesis. Life Sci. 2020;254:116900.
   PubMed Web of Science ®Google Scholar
• Peng W-X, Koirala P, Mo -Y-Y. LncRNA-mediated regulation of cell signaling in cancer. Oncogene. 2017;36(41):5661–5667.
   PubMed Web of Science ®Google Scholar
• Gu Y, Niu S, Wang Y, et al. DMDRMR-mediated regulation of m 6 A-modified CDK4 by m 6A Reader IGF2BP3 drives ccRCC progression. Cancer Res. 2021;81(4):923 LP– 934.
   Web of Science ®Google Scholar
• Wang P, Chen W, Ma T, et al. lncRNA lnc-TSI inhibits metastasis of clear cell renal cell carcinoma by suppressing TGF-β-induced epithelial-mesenchymal transition. Mol Ther Nucleic Acids. 2020;22:1–16.
   PubMed Web of Science ®Google Scholar
• Li J-K, Chen C, Liu J-Y, et al. Long noncoding RNA MRCCAT1 promotes metastasis of clear cell renal cell carcinoma via inhibiting NPR3 and activating p38-MAPK signaling. Mol Cancer. 2017;16(1):111.
   PubMed Web of Science ®Google Scholar
• Ding C, Han F, Xiang H, et al. LncRNA CRNDE is a biomarker for clinical progression and poor prognosis in clear cell renal cell carcinoma. J Cell Biochem. 2018;119(12):10406–10414. https://doi.org/10.1002/jcb.27389
   PubMed Web of Science ®Google Scholar
• Ma J, Qi G, Li L. LncRNA NNT-AS1 promotes lung squamous cell carcinoma progression by regulating the miR-22/FOXM1 axis. Cell Mol Biol Lett. 2020;25(1):34.
   PubMed Web of Science ®Google Scholar
• Zheng D, Chen D, Lin F, et al. LncRNA NNT-AS1 promote glioma cell proliferation and metastases through miR-494-3p/PRMT1 axis. Cell Cycle. 2020;19(13):1621–1631. Georgetown, Tex.
   PubMed Web of Science ®Google Scholar
• Liu Y, Guo R, Qiao Y, et al. LncRNA NNT-AS1 contributes to the cisplatin resistance of cervical cancer through NNT-AS1/miR-186/HMGB1 axis. Cancer Cell Int. 2020;20(1):190.
   PubMed Web of Science ®Google Scholar
• Lu TX, Rothenberg ME. MicroRNA. J Allergy Clin Immunol. 2018;141(4):1202–1207. https://doi.org/10.1016/j.jaci.2017.08.034
   PubMed Web of Science ®Google Scholar
• Ding L, Jiang M, Wang R, et al. The emerging role of small non-coding RNA in renal cell carcinoma. Transl Oncol. 2021;14(1):100974.
   PubMed Web of Science ®Google Scholar
• Kandettu A, Radhakrishnan R, Chakrabarty S, et al., The emerging role of miRNA clusters in breast cancer progression. Biochim Biophys Acta Rev Cancer. 2020;1874(2):188413. https://doi.org/10.1016/j.bbcan.2020.188413.
   Google Scholar
• Jingushi K, Ueda Y, Kitae K, et al. miR-629 targets TRIM33 to promote TGFβ/Smad signaling and metastatic phenotypes in ccRCC. Mol Cancer Res. 2015;13(3):565 LP– 574.
   Web of Science ®Google Scholar
• Wang K, Sun Y, Tao W, et al. Androgen receptor (AR) promotes clear cell renal cell carcinoma (ccRCC) migration and invasion via altering the circHIAT1/miR-195-5p/29a-3p/29c-3p/CDC42 signals. Cancer Lett. 2017;394:1–12.
   PubMed Web of Science ®Google Scholar
• Chen L, Xie Y, Ma X, et al. SOX6 represses tumor growth of clear cell renal cell carcinoma by HMG domain-dependent regulation of Wnt/β-catenin signaling. Mol Carcinog. 2020;59(10):1159–1173.
   PubMed Web of Science ®Google Scholar
• Wang K, Chen X, Zhan Y, et al. miR-335 inhibits the proliferation and invasion of clear cell renal cell carcinoma cells through direct suppression of BCL-W. Tumor Biol. 2015;36(9):6875–6882. https://doi.org/10.1007/s13277-015-3382-6
   PubMedGoogle Scholar
• Chen Q, Liu T, Bao Y, et al. CircRNA cRAPGEF5 inhibits the growth and metastasis of renal cell carcinoma via the miR-27a-3p/TXNIP pathway. Cancer Lett. 2020;469:68–77.
   PubMed Web of Science ®Google Scholar
• Zheng Z, Chen Z, Zhong Q, et al. CircPVT1 promotes progression in clear cell renal cell carcinoma by sponging miR-145-5p and regulating TBX15 expression. Cancer Sci. 2021;112(4):1443–1456.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Wang Y. Circular RNAs in hepatocellular carcinoma: emerging functions to clinical significances. Front Oncol. 2021;11:667428.
   PubMed Web of Science ®Google Scholar
• Winkle M, El-Daly SM, Fabbri M, et al. Noncoding RNA therapeutics - challenges and potential solutions. Nat Rev Drug Discov. 2021;1–23. 10.1038/s41573-021-00219-z
   PubMed Web of Science ®Google Scholar
• Ju X, Sun Y, Zhang F, et al. Long non-coding RNA LINC02747 promotes the proliferation of clear cell renal cell carcinoma by inhibiting miR-608 and activating TFE3. Front Oncol. 2020;10:573789.
   PubMed Web of Science ®Google Scholar
• Jiao M, Guo H, Chen Y, et al. DARS-AS1 promotes clear cell renal cell carcinoma by sequestering miR-194-5p to up-regulate DARS. Biomed Pharmacother. 2020;128:110323.
   PubMed Web of Science ®Google Scholar
• Li X, Wang X, Cheng Z, et al., AGO2 and its partners: a silencing complex, a chromatin modulator, and new features. Crit Rev Biochem Mol Biol. 2020;55(1):33–53. https://doi.org/10.1080/10409238.2020.1738331.
   Google Scholar
• Chen J, Zhong Y, Li L. miR-124 and miR-203 synergistically inactivate EMT pathway via coregulation of ZEB2 in clear cell renal cell carcinoma (ccRCC). J Transl Med. 2020;18(1):69. https://doi.org/10.1186/s12967-020-02242-x
   PubMed Web of Science ®Google Scholar
• Jingushi K, Kashiwagi Y, Ueda Y, et al. High miR-122 expression promotes malignant phenotypes in ccRCC by targeting occludin. Int J Oncol. 2017;51(1):289–297.
   PubMed Web of Science ®Google Scholar
• Luo M, Wu L, Zhang K, et al. miR-137 regulates ferroptosis by targeting glutamine transporter SLC1A5 in melanoma. Cell Death Differ. 2018;25(8):1457–1472. https://doi.org/10.1038/s41418-017-0053-8
   PubMed Web of Science ®Google Scholar
• Ding F, Zhang S, Gao S, et al. MiR-137 functions as a tumor suppressor in pancreatic cancer by targeting MRGBP. J Cell Biochem. 2018;119(6):4799–4807. https://doi.org/10.1002/jcb.26676
   PubMed Web of Science ®Google Scholar
• Zang Y, Zhu J, Li Q, et al. miR-137-3p modulates the progression of prostate cancer by regulating the JNK3/EZH2 axis. Onco Targets Ther. 2020;13:7921–7932.
   PubMed Web of Science ®Google Scholar