Combinative treatment of Curdione and docetaxel triggers reactive oxygen species (ROS)-mediated intrinsic apoptosis of triple-negative breast cancer cells

References

• Yin L, Duan JJ, Bian XW, et al. Triple-negative breast cancer molecular subtyping and treatment progress. Breast Cancer Res. 2020;22(1):61.
   PubMed Web of Science ®Google Scholar
• Borri F, Granaglia A. Pathology of triple negative breast cancer. Semin Cancer Biol. 2021;72:136-145
   Google Scholar
• Medina MA, Oza G, Sharma A, et al. Triple-negative breast cancer: a review of conventional and advanced therapeutic strategies. Int J Environ Res Public Health. 2020;17(6):6.
   Web of Science ®Google Scholar
• Ghafouri-Fard S, Shoorei H, Branicki W, et al. Non-coding RNA profile in lung cancer. Exp Mol Pathol. 2020;114:104411.
   PubMed Web of Science ®Google Scholar
• Lehmann BD, Jovanović B, Chen X, et al. Refinement of triple-negative breast cancer molecular subtypes: implications for neoadjuvant chemotherapy selection. PLoS One. 2016;11(6):e0157368.
   PubMed Web of Science ®Google Scholar
• Vagia E, Mahalingam D, Cristofanilli M. The Landscape of targeted therapies in TNBC. Cancers (Basel). 2020;12(4):4.
   Web of Science ®Google Scholar
• Sorbe B, Graflund M, Nygren L, et al. A study of docetaxel weekly or every three weeks in combination with carboplatin as first line chemotherapy in epithelial ovarian cancer: hematological and non-hematological toxicity profiles. Oncol Lett. 2013;5(4):1140–1148.
   PubMed Web of Science ®Google Scholar
• Rochigneux P, Schleinitz N, Ebbo M, et al. Acute myositis: an unusual and severe side effect of docetaxel: a case report and literature review. Anticancer Drugs. 2018;29(5):477–481.
   PubMed Web of Science ®Google Scholar
• Thomas J, Warrier A, Kachare N. Docetaxel-Induced myositis. J Clin Rheumatol. 2020;26(3):e62–62e63.
   PubMed Web of Science ®Google Scholar
• Falls-Hubert KC, Butler AL, Gui K, et al. Disulfiram causes selective hypoxic cancer cell toxicity and radio-chemo-sensitization via redox cycling of copper. Free Radic Biol Med. 2020;150:1–11.
   PubMed Web of Science ®Google Scholar
• Lee YH, Pang SW, Revai LE, et al. Tricistronic expression of MOAP-1, Bax and RASSF1A in cancer cells enhances chemo-sensitization that requires BH3L domain of MOAP-1. J Cancer Res Clin Oncol. 2020;146(7):1751–1764.
   PubMed Web of Science ®Google Scholar
• Hashem S, Nisar S, Sageena G, et al. therapeutic effects of curcumol in several diseases; an overview. Nutr Cancer. 2021;73(2):181–195.
   PubMed Web of Science ®Google Scholar
• Ekor M. The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety. Front Pharmacol. 2014;4:177.
   PubMed Web of Science ®Google Scholar
• Yin G, Cheng X, Tao W, et al. Comparative analysis of multiple representative components in the herb pair astragali radix-curcumae rhizoma and its single herbs by UPLC-QQQ-MS. J Pharm Biomed Anal. 2018;148:224–229.
   PubMed Web of Science ®Google Scholar
• Dhifi W, Bellili S, Jazi S, et al. Essential oils’ chemical characterization and investigation of some biological activities: a critical review. Med (Basel). 2016;3:4.
   Google Scholar
• Li T, Zhang S, Chen F, et al. Formononetin ameliorates the drug resistance of Taxol resistant triple negative breast cancer by inhibiting autophagy. Am J Transl Res. 2021;13(2):497–514.
   PubMed Web of Science ®Google Scholar
• Zeng C, Fan D, Xu Y, et al. Curcumol enhances the sensitivity of doxorubicin in triple-negative breast cancer via regulating the miR-181b-2-3p-ABCC3 axis. Biochem Pharmacol. 2020;174:113795.
   PubMed Web of Science ®Google Scholar
• Di MM, Garzoli S, Sabatino M, et al. Antitumor effect of Melaleuca alternifolia essential oil and its main component terpinen-4-ol in combination with target therapy in melanoma models. Cell Death Discov. 2021;7(1):127.
   PubMed Web of Science ®Google Scholar
• Bijnsdorp IV, Giovannetti E, Peters GJ. Analysis of drug interactions. Methods Mol Biol. 2011;731:421–434.
   PubMedGoogle Scholar
• Kopeina GS, Prokhorova EA, Lavrik IN, et al. Alterations in the nucleocytoplasmic transport in apoptosis: caspases lead the way. Cell Prolif. 2018;51(5):e12467.
   PubMed Web of Science ®Google Scholar
• LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. 2012. Bethesda (MD). National Institute of Diabetes and Digestive and Kidney Diseases.
   Google Scholar
• Steinberg RL, Thomas LJ, Brooks N, et al. Multi-institution evaluation of sequential gemcitabine and docetaxel as rescue therapy for nonmuscle invasive bladder cancer. J Urol. 2020;203(5):902–909.
   PubMed Web of Science ®Google Scholar
• Gąsiorkiewicz BM, Koczurkiewicz-Adamczyk P, Piska K, et al. Autophagy modulating agents as chemosensitizers for cisplatin therapy in cancer. Invest New Drugs. 2020;
   PubMed Web of Science ®Google Scholar
• Koczurkiewicz-Adamczyk P, Piska K, Gunia-Krzyżak A, et al. Cinnamic acid derivatives as chemosensitising agents against DOX-treated lung cancer cells - Involvement of carbonyl reductase 1. Eur J Pharm Sci. 2020;154:105511.
   PubMed Web of Science ®Google Scholar
• Bu L, Dai O, Zhou F, et al. Traditional Chinese medicine formulas, extracts, and compounds promote angiogenesis. Biomed Pharmacother. 2020;132:110855.
   PubMed Web of Science ®Google Scholar
• Wang J, Wong YK, Liao F. What has traditional Chinese medicine delivered for modern medicine. Expert Rev Mol Med. 2018;20:e4.
   Google Scholar
• Yi Y, Li CY, Zhao Y, et al. [Safety of animal traditional Chinese medicine (TCM) injections]. Zhongguo Zhong Yao Za Zhi. 2018;43(22):4391–4396.
   PubMedGoogle Scholar
• Willenbacher E, Khan SZ, Sca M, et al. Curcumin: new Insights into an Ancient Ingredient against Cancer. Int J Mol Sci. 2019;20(8):8.
   Web of Science ®Google Scholar
• Qu J, Lu W, Chen M, et al. Combined effect of recombinant human adenovirus p53 and curcumin in the treatment of liver cancer. Exp Ther Med. 2020;20(5):18.
   PubMed Web of Science ®Google Scholar
• Jaiswal S, Mishra P. Co-delivery of curcumin and serratiopeptidase in HeLa and MCF-7 cells through nanoparticles show improved anti-cancer activity. Mater Sci Eng C Mater Biol Appl. 2018;92:673–684.
   PubMed Web of Science ®Google Scholar
• Cai F, Chen M, Zha D, et al. Curcumol potentiates celecoxib-induced growth inhibition and apoptosis in human non-small cell lung cancer. Oncotarget. 2017;8(70):115526–115545.
   PubMedGoogle Scholar
• Chen G, Wang Y, Li M, et al. Curcumol induces HSC-T6 cell death through suppression of Bcl-2: involvement of PI3K and NF-κB pathways. Eur J Pharm Sci. 2014;65:21–28.
   PubMed Web of Science ®Google Scholar
• Liu H, Wang J, Tao Y, et al. Curcumol inhibits colorectal cancer proliferation by targeting miR-21 and modulated PTEN/PI3K/Akt pathways. Life Sci. 2019;221:354–361.
   PubMed Web of Science ®Google Scholar
• Li X, Liu H, Wang J, et al. Curcumol induces cell cycle arrest and apoptosis by inhibiting IGF-1R/PI3K/Akt signaling pathway in human nasopharyngeal carcinoma CNE-2 cells. Phytother Res. 2018;32(11):2214–2225.
   PubMed Web of Science ®Google Scholar
• Wang J, Huang F, Bai Z, et al. Curcumol inhibits growth and induces apoptosis of colorectal cancer LoVo cell Line via IGF-1R and p38 MAPK pathway. Int J Mol Sci. 2015;16(8):19851–19867.
   PubMed Web of Science ®Google Scholar
• Liu P, Miao K, Zhang L, et al. Curdione ameliorates bleomycin-induced pulmonary fibrosis by repressing TGF-β-induced fibroblast to myofibroblast differentiation. Respir Res. 2020;21(1):58.
   PubMed Web of Science ®Google Scholar
• Nedeljković M, Damjanović A. Mechanisms of chemotherapy resistance in triple-negative breast cancer-how we can rise to the challenge. Cells 2019;8(9):9.
   Web of Science ®Google Scholar
• Xu Z, Han X, Ou D, et al. Targeting PI3K/AKT/mTOR-mediated autophagy for tumor therapy. Appl Microbiol Biotechnol. 2020;104(2):575–587.
   PubMed Web of Science ®Google Scholar
• Johnson DE, O’Keefe RA, Grandis JR. Targeting the IL-6/JAK/STAT3 signalling axis in cancer. Nat Rev Clin Oncol. 2018;15(4):234–248.
   PubMed Web of Science ®Google Scholar
• Zhou Z, Ni K, Deng H, et al. Dancing with reactive oxygen species generation and elimination in nanotheranostics for disease treatment. Adv Drug Deliv Rev. 2020;158:73–90.
   PubMed Web of Science ®Google Scholar
• Galadari S, Rahman A, Pallichankandy S, et al. Reactive oxygen species and cancer paradox: to promote or to suppress. Free Radic Biol Med. 2017;104:144–164.
   PubMed Web of Science ®Google Scholar
• Wang J, Li XM, Bai Z, et al. Curcumol induces cell cycle arrest in colon cancer cells via reactive oxygen species and Akt/ GSK3β/cyclin D1 pathway. J Ethnopharmacol. 2018;210:1–9.
   PubMed Web of Science ®Google Scholar
• Zang S, Tang Q, Dong F, et al. Curcumol inhibits the proliferation of gastric adenocarcinoma MGC-803 cells via downregulation of IDH1. Oncol Rep. 2017;38(6):3583–3591.
   PubMed Web of Science ®Google Scholar
• Shi XJ, Yu B, Wang JW, et al. Structurally novel steroidal spirooxindole by241 potently inhibits tumor growth mainly through ROS-mediated mechanisms. Sci Rep. 2016;6(1):31607.
   PubMed Web of Science ®Google Scholar
• Zhao X, Xu L, Zheng L, et al. Potent effects of dioscin against gastric cancer in vitro and in vivo. Phytomedicine. 2016;23(3):274–282.
   PubMed Web of Science ®Google Scholar
• Zhou Y, Wei L, Zhang H, et al. FV-429 induced apoptosis through ROS-mediated ERK2 nuclear translocation and p53 activation in gastric cancer cells. J Cell Biochem. 2015;116(8):1624–1637.
   PubMed Web of Science ®Google Scholar
• Li M, Gao P, Zhang J. Crosstalk between autophagy and apoptosis: potential and emerging therapeutic targets for Cardiac diseases. Int J Mol Sci. 2016;17(3):332.
   PubMed Web of Science ®Google Scholar