2,403
Views
15
CrossRef citations to date
0
Altmetric
Research paper

Long non-coding RNA NORAD protects against cerebral ischemia/reperfusion injury induced brain damage, cell apoptosis, oxidative stress and inflammation by regulating miR-30a-5p/YWHAG

, , , , , & show all
Pages 9174-9188 | Received 01 Jun 2021, Accepted 13 Oct 2021, Published online: 22 Nov 2021

References

  • Roy-O’Reilly M, McCullough LD. Age and sex are critical factors in ischemic stroke pathology. Endocrinology. 2018;159(8):3120–3131.
  • Manuel GE, Johnson T, Liu D. Therapeutic angiogenesis of exosomes for ischemic stroke. Int J Physiol Pathophysiol Pharmacol. 2017;9(6):188–191.
  • Sommer CJ. Ischemic stroke: experimental models and reality. Acta Neuropathol. 2017;133(2):245–261.
  • Wang M, Wang J, Liu Z, et al. Effects of intermedin on autophagy in cerebral ischemia/reperfusion injury. Neuropeptides. 2018;68:15–21.
  • Li Z, Yulei J, Yaqing J, et al. Protective effects of tetramethylpyrazine analogue Z-11 on cerebral ischemia reperfusion injury. Eur J Pharmacol. 2019;844:156–164.
  • Wu MY, Yiang GT, Liao WT, et al. Current mechanistic concepts in ischemia and reperfusion injury. Cell Physiol Biochem. 2018;46(4):1650–1667.
  • Patel R, McMullen PW. Neuroprotection in the Treatment of Acute Ischemic Stroke. Prog Cardiovasc Dis. 2017;59(6):542–548.
  • Tripathi S, Shree B, Mohapatra S, et al. The expanding regulatory mechanisms and cellular functions of long non-coding RNAs (lncRNAs) in neuroinflammation. Mol Neurobiol. 2021;58(6):2916–2939.
  • Vasudeva K, Dutta A, Munshi A. Role of lncRNAs in the development of ischemic stroke and their therapeutic potential. Mol Neurobiol. 2021;58(8):3712–3728.
  • Gan L, Liao S, Xing Y, et al. The regulatory functions of lncRNAs on angiogenesis following ischemic stroke. Front Mol Neurosci. 2020;13:613976.
  • Song Q, Geng Y, Li Y, et al. Long noncoding RNA NORAD regulates MPP+-induced Parkinson’s disease model cells. J Chem Neuroanat. 2019;101:101668.
  • Fan Y, Wei L, Zhang S, et al. LncRNA SNHG15 knockdown protects against OGD/R-induced neuron injury by downregulating TP53INP1 expression via binding to miR-455-3p. Neurochem Res. 2021;46(4):1019–1030.
  • Zhong Y, Yu C, Qin W. LncRNA SNHG14 promotes inflammatory response induced by cerebral ischemia/reperfusion injury through regulating miR-136-5p /ROCK1. Cancer Gene Ther. 2019;26(7–8):234–247.
  • Long G, Wang F, Li H, et al. Circulating miR-30a, miR-126 and let-7b as biomarker for ischemic stroke in humans. BMC Neurol. 2013;13:178.
  • Wang P, Pan R, Weaver J, et al. MicroRNA-30a regulates acute cerebral ischemia-induced blood-brain barrier damage through ZnT4/zinc pathway. J Cereb Blood Flow Metab. 2021;41(3):641–655.
  • Sonntag T, Vaughan JM, Montminy M. 14-3-3 proteins mediate inhibitory effects of cAMP on salt-inducible kinases (SIKs). FEBS J. 2018;285(3):467–480.
  • Ramocki MB, Bartnik M, Szafranski P, et al. Recurrent distal 7q11.23 deletion including HIP1 and YWHAG identified in patients with intellectual disabilities, epilepsy, and neurobehavioral problems. Am J Hum Genet. 2010;87(6):857–865.
  • Kawamoto Y, Akiguchi I, Tomimoto H, et al. Upregulated expression of 14-3-3 proteins in astrocytes from human cerebrovascular ischemic lesions. Stroke. 2006;37(3):830–835.
  • Lai XJ, Ye SQ, Zheng L, et al. Selective 14-3-3γ induction quenches p-β-catenin Ser37/Bax-enhanced cell death in cerebral cortical neurons during ischemia. Cell Death Dis. 2014;5:e1184.
  • Zhou XY, Hu DX, Chen RQ, et al. 14-3-3 isoforms differentially regulate NFκB signaling in the brain after ischemia-reperfusion. Neurochem Res. 2017;42(8):2354–2362.
  • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 2001;25(4):402–408.
  • Rabinstein AA. Treatment of acute ischemic stroke. Continuum (Minneap Minn). 2017;23(1,Cerebrovascular Disease):62–81.
  • Wang J, Cao B, Han D, et al. Long non-coding RNA H19 induces cerebral ischemia reperfusion injury via activation of autophagy. Aging Dis. 2017;8(1):71–84.
  • Chen H, Li X. LncRNA ROR is involved in cerebral hypoxia/reoxygenation-induced injury in PC12 cells via regulating miR-135a-5p/ROCK1/2. Am J Transl Res. 2019;11(9):6145–6158.
  • Zhang XC, Gu AP, Zheng CY, et al. YY1/LncRNA GAS5 complex aggravates cerebral ischemia/reperfusion injury through enhancing neuronal glycolysis. Neuropharmacology. 2019;158:107682.
  • Yao X, Yao R, Huang F, et al. LncRNA SNHG12 as a potent autophagy inducer exerts neuroprotective effects against cerebral ischemia/reperfusion injury. Biochem Biophys Res Commun. 2019;514(2):490–496.
  • Jurisic V, Radenkovic S, Konjevic G. The actual role of LDH as tumor marker, biochemical and clinical aspects. Adv Exp Med Biol. 2015;867:115–124.
  • Jurisic V, Srdic-Rajic T, Konjevic G, et al. TNF-α induced apoptosis is accompanied with rapid CD30 and slower CD45 shedding from K-562 cells. J Membr Biol. 2011;239(3):115–122.
  • Lu TX, Rothenberg ME. MicroRNA. J Allergy Clin Immunol. 2018;141(4):1202–1207.
  • Pan H, Zhao F, Yang Y, et al. Overexpression of long non-coding RNA SNHG16 against cerebral ischemia-reperfusion injury through miR-106b-5p/LIMK1 axis. Life Sci. 2020;254:117778.
  • Gao N, Tang H, Gao L, et al. LncRNA H19 aggravates cerebral ischemia/reperfusion injury by functioning as a ceRNA for miR-19a-3p to Target PTEN. Neuroscience. 2020;437:117–129.
  • Giles N, Forrest A, Gabrielli B. 14-3-3 acts as an intramolecular bridge to regulate cdc25B localization and activity. J Biol Chem. 2003;278(31):28580–28587.