1,748
Views
1
CrossRef citations to date
0
Altmetric
Research Paper

LIM domain-containing 2 (LIMD2) promotes the progress of ovarian cancer via the focal adhesion signaling pathway

, , &
Pages 10089-10100 | Received 08 Aug 2021, Accepted 27 Oct 2021, Published online: 10 Dec 2021

References

  • Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–249.
  • Jayson GC, Kohn EC, Kitchener HC, et al. Ovarian cancer. Lancet. 2014;384(9951):1376–1388.
  • Torre LA, Trabert B, DeSantis CE, et al. Ovarian cancer statistics, 2018. CA Cancer J Clin. 2018;68(4):284–296.
  • Lheureux S, Braunstein M, Oza AM. Epithelial ovarian cancer: evolution of management in the era of precision medicine. CA Cancer J Clin. 2019;69(4):280–304.
  • Brenner DR, Weir HK, Demers AA, et al. Projected estimates of cancer in Canada in 2020. CMAJ. 2020;192(9):E199–E205. E199-E205.
  • Malapelle U. USP11 role in colorectal cancer growing and metastatisation. EBioMedicine. 2019;48:5–6.
  • Cerutti JM, Oler G, Michaluart P, et al. Molecular profiling of matched samples identifies biomarkers of papillary thyroid carcinoma lymph node metastasis. Cancer Res. 2007;67(16):7885–7892.
  • Koch BJ, Ryan JF, Baxevanis AD. The diversification of the LIM superclass at the base of the metazoa increased subcellular complexity and promoted multicellular specialization. PLoS One. 2012;7(3):e33261.
  • Matthews JM, Lester K, Joseph S, et al. LIM-domain-only proteins in cancer. Nat Rev Cancer. 2013;13(2):111–122.
  • Pinheiro Dos Santos MJC, Bastos AU, Da Costa VR, et al. LIMD2 is overexpressed in BRAF V600E-positive papillary thyroid carcinomas and matched lymph node metastases. Endocr Pathol. 2018;29(3):222–230.
  • Zhang F,Qin S, Xiao X, et al. Overexpression of LIMD2 promotes the progression of non-small cell lung cancer. Oncol Lett. 2019;18(2):2073–2081.
  • Wang F, Li Z, Xu L, et al. LIMD2 targeted by miR34a promotes the proliferation and invasion of nonsmall cell lung cancer cells. Mol Med Rep. 2018;18(5):4760–4766.
  • Peng H, Talebzadeh-Farrooji M, Osborne MJ, et al. LIMD2 is a small LIM-only protein overexpressed in metastatic lesions that regulates cell motility and tumor progression by directly binding to and activating the integrin-linked kinase. Cancer Res. 2014;74(5):1390–1403.
  • Yen L, Benlimame N, Nie Z-R, et al. Differential regulation of tumor angiogenesis by distinct ErbB homo- and heterodimers. Mol Biol Cell. 2002;13(11):4029–4044.
  • Wang Y, Jin W, Jia X, et al. Transcriptional repression of CDKN2D by PML/RARalpha contributes to the altered proliferation and differentiation block of acute promyelocytic leukemia cells. Cell Death Dis. 2014;5(10):e1431.
  • Dundon WG, Settypalli TBK, Spiegel K, et al. Comparison of eleven in vitro diagnostic assays for the detection of SARS-CoV-2 RNA. J Virol Methods. 2021;295:114200.
  • Zhao B, Song X, Guan H. CircACAP2 promotes breast cancer proliferation and metastasis by targeting miR-29a/b-3p-COL5A1 axis. Life Sci. 2020;244:117179.
  • Sun P, Quan J-C, Wang S, et al. lncRNA-PACER upregulates COX-2 and PGE2 through the NF-κB pathway to promote the proliferation and invasion of colorectal-cancer cells. Gastroenterol Rep (Oxf). 2021;9(3):257–268.
  • Han W, Zhang Y, Niu C, et al. BTB and CNC homology 1 (Bach1) promotes human ovarian cancer cell metastasis by HMGA2-mediated epithelial-mesenchymal transition. Cancer Lett. 2019;445:45–56.
  • Zhang Q, Hao L, Shen Z, et al. MiR-186-5p suppresses cell migration, invasion, and epithelial mesenchymal transition in bladder cancer by targeting RAB27A/B. Environ Toxicol. 2021;36(11):2174–2185.
  • Zhang J, Wu L, Lian C, et al. Nitidine chloride possesses anticancer property in lung cancer cells through activating Hippo signaling pathway. Cell Death Discov. 2020;6(1):91.
  • Bobbs AS, Cole JM, Cowden Dahl KD. Emerging and evolving ovarian cancer animal models. Cancer Growth Metastasis. 2015;8(Suppl 1):29–36.
  • Shaw TJ, Senterman MK, Dawson K, et al. Characterization of intraperitoneal, orthotopic, and metastatic xenograft models of human ovarian cancer. Mol Ther. 2004;10(6):1032–1042.
  • Huang J, Zhang L, Chen J, et al. The landscape of immune cells indicates prognosis and applicability of checkpoint therapy in hepatocellular carcinoma. Front Oncol. 2021;11:744951.
  • Guan X. Cancer metastases: challenges and opportunities. Acta Pharm Sin B. 2015;5(5):402–418.
  • Webb PM, Jordan SJ. Epidemiology of epithelial ovarian cancer. Best Pract Res Clin Obstet Gynaecol. 2017;41:3–14.
  • Cramer DW, Bast RC Jr, Berg CD, et al. Ovarian cancer biomarker performance in prostate, lung, colorectal, and ovarian cancer screening trial specimens. Cancer Prev Res (Phila). 2011;4(3):365–374.
  • Nash Z, Menon U. Ovarian cancer screening: current status and future directions. Best Pract Res Clin Obstet Gynaecol. 2020;65:32–45.
  • Drescher CW, Shah C, Thorpe J, et al. Longitudinal screening algorithm that incorporates change over time in CA125 levels identifies ovarian cancer earlier than a single-threshold rule. J Clin Oncol. 2013;31(3):387–392.
  • Russell MR, Walker MJ, Williamson AJK, et al. Protein Z: a putative novel biomarker for early detection of ovarian cancer. Int J Cancer. 2016;138(12):2984–2992.
  • Brown S, Coghill ID, McGrath MJ, et al. Role of LIM domains in mediating signaling protein interactions. IUBMB Life. 2001;51(6):359–364.
  • Araldi RP, de Melo TC, Levy D, et al. LIMD2 regulates key steps of metastasis cascade in papillary thyroid cancer cells via MAPK crosstalk. Cells. 2020;9(11):11.
  • Golubovskaya VM, Kweh FA, Cance WG. Focal adhesion kinase and cancer. Histol Histopathol. 2009;24(4):503–510.
  • Tai YL, Chen LC, Shen TL. Emerging roles of focal adhesion kinase in cancer. Biomed Res Int. 2015;2015:690690.
  • Choe SR, Kim YN, Park CG, et al. RCP induces FAK phosphorylation and ovarian cancer cell invasion with inhibition by curcumin. Exp Mol Med. 2018;50(4):1–10.
  • Nolasco-Quiroga M, Rosas-Díaz M, Moreno J, et al. Increased expression of FAK isoforms as potential cancer biomarkers in ovarian cancer. Oncol Lett. 2019;17(6):4779–4786.
  • Diaz Osterman CJ, Ozmadenci D, Kleinschmidt EG, et al. FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy. Elife. 2019;8:e47327.
  • Sood AK, Armaiz-Pena GN, Halder J, et al. Adrenergic modulation of focal adhesion kinase protects human ovarian cancer cells from anoikis. J Clin Invest. 2010;120(5):1515–1523.
  • Mitra AK, Sawada K, Tiwari P, et al. Ligand-independent activation of c-Met by fibronectin and alpha(5)beta(1)-integrin regulates ovarian cancer invasion and metastasis. Oncogene. 2011;30(13):1566–1576.
  • Golubovskaya VM. Targeting FAK in human cancer: from finding to first clinical trials. Front Biosci (Landmark Ed). 2014;19(4):687–706.
  • Begum A, Ewachiw T, Jung C, et al. The extracellular matrix and focal adhesion kinase signaling regulate cancer stem cell function in pancreatic ductal adenocarcinoma. PLoS One. 2017;12(7):e0180181.
  • Chen CH, Shyu M-K, Wang S-W, et al. MUC20 promotes aggressive phenotypes of epithelial ovarian cancer cells via activation of the integrin beta1 pathway. Gynecol Oncol. 2016;140(1):131–137.