Polygonatum sibiricum polysaccharides (PSP) improve the palmitic acid (PA)-induced inhibition of survival, inflammation, and glucose uptake in skeletal muscle cells

References

• Cho NH, Shaw JE, Karuranga S, et al. IDF diabetes Atlas: global estimates of diabetes prevalence for 2017 and projections for 2045. Diabetes Res Clin Pract. 2018;138:271–281.
   PubMed Web of Science ®Google Scholar
• Nelson BA, Robinson KA, Buse MG. High glucose and glucosamine induce insulin resistance via different mechanisms in 3T3-L1 adipocytes. Diabetes. 2000;49(6):981–991.
   PubMed Web of Science ®Google Scholar
• Meng J, Zhu Y, Ma H, et al. The role of traditional Chinese medicine in the treatment of cognitive dysfunction in type 2 diabetes. J Ethnopharmacol. 2021;280:114464.
   PubMed Web of Science ®Google Scholar
• Yu X, Chau JPC, Huo L. The effectiveness of traditional Chinese medicine-based lifestyle interventions on biomedical, psychosocial, and behavioral outcomes in individuals with type 2 diabetes: a systematic review with meta-analysis. Int J Nurs Stud. 2018;80:165–180.
   PubMed Web of Science ®Google Scholar
• Liu M, Liu Z, Xu B, et al. Review of systematic reviews and meta-analyses investigating traditional chinese medicine treatment for type 2 diabetes mellitus. J Tradit Chin Med. 2016;36(5):555–563.
   PubMed Web of Science ®Google Scholar
• Yelithao K, Surayot U, Lee JH, et al. RAW264.7 cell activating glucomannans extracted from rhizome of polygonatum sibiricum. Prev Nutr Food Sci. 2016;21(3):245–254.
   PubMedGoogle Scholar
• Li C, Li J, Shang Y, et al. Hypoglycemic and hypolipidemic activity polygonatum sibiricum fermented with lactobacillus brevis YM 1301 in diabetic C57BL/6 mice. J Med Food. 2021;24(7):720–731.
   PubMed Web of Science ®Google Scholar
• Wang J, Chu H, Li H, et al. A network pharmacology approach to investigate the mechanism of erjing prescription in type 2 diabetes. Evid Based Complement Alternat Med. 2021;2021:9933236.
   PubMed Web of Science ®Google Scholar
• Cui X, Wang S, Cao H, et al. A review: the bioactivities and pharmacological applications of polygonatum sibiricum polysaccharides. Molecules. 2018;23(5):1170.
   PubMed Web of Science ®Google Scholar
• Cai J, Zhu Y, Zuo Y, et al. Polygonatum sibiricum polysaccharide alleviates inflammatory cytokines and promotes glucose uptake in high‑glucose‑ and high‑insulin‑induced 3T3‑L1 adipocytes by promoting Nrf2 expression. Mol Med Rep. 2019;20:3951–3958.
   PubMed Web of Science ®Google Scholar
• Huang Y, Yan Y, Xv W, et al. A new insight into the roles of MiRNAs in metabolic syndrome. Biomed Res Int. 2018;2018:7372636.
   PubMed Web of Science ®Google Scholar
• Eyileten C, Wicik Z, Dr S, et al. MicroRNAs as diagnostic and prognostic biomarkers in ischemic stroke-A comprehensive review and bioinformatic analysis. Cells. 2018;7(12):249.
   PubMed Web of Science ®Google Scholar
• Zhou T, Meng X, Che H, et al. Regulation of insulin resistance by multiple MiRNAs via targeting the GLUT4 signalling pathway. Cell Physiol Biochem. 2016;38(5):2063–2078.
   PubMedGoogle Scholar
• Wang J, Gao Y, Duan L, et al. Metformin ameliorates skeletal muscle insulin resistance by inhibiting miR-21 expression in a high-fat dietary rat model. Oncotarget. 2017;8(58):98029–98039.
   PubMedGoogle Scholar
• Dai L, Jie S, Bi S, et al. Angiopoietin-2 silence alleviates lipopolysaccharide-induced inflammation, barrier dysfunction and endoplasmic reticulum stress of intestinal epithelial cells by blocking notch signaling pathway. Bioengineered. 2021;12(1):8116–8124.
   PubMed Web of Science ®Google Scholar
• Park S, Baek K, Choi C. Suppression of adipogenic differentiation by muscle cell-induced decrease in genes related to lipogenesis in muscle and fat co-culture system. Cell Biol Int. 2013;37(9):1003–1009.
   PubMed Web of Science ®Google Scholar
• Latouche C, Natoli A, Reddy-Luthmoodoo M, et al. MicroRNA-194 modulates glucose metabolism and its skeletal muscle expression is reduced in diabetes. PLoS One. 2016;11(5):e0155108.
   PubMed Web of Science ®Google Scholar
• Agarwal V, Bell GW, Nam JW, et al. Predicting effective microRNA target sites in mammalian mRNAs. Elife. 2015;4:e05005.
   PubMed Web of Science ®Google Scholar
• Chen Y, Wang X. miRDB: an online database for prediction of functional microRNA targets. Nucleic Acids Res. 2020;48(D1):D127–d31.
   PubMed Web of Science ®Google Scholar
• Sticht C, De La Torre C, Parveen A, et al. miRWalk: an online resource for prediction of microRNA binding sites. PLoS One. 2018;13(10):e0206239.
   PubMed Web of Science ®Google Scholar
• Jain P, Vig S, Datta M, et al. Systems biology approach reveals genome to phenome correlation in type 2 diabetes. PLoS One. 2013;8(1):e53522.
   PubMed Web of Science ®Google Scholar
• Queiroz AL, Lessard SJ, Ouchida AT, et al. The MicroRNA miR-696 is regulated by SNARK and reduces mitochondrial activity in mouse skeletal muscle through Pgc1α inhibition. Mol Metab. 2021;51:101226.
   PubMed Web of Science ®Google Scholar
• Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001;25(4):402–408.
   PubMed Web of Science ®Google Scholar
• Guo X, Sun W, Xu G, et al. RNA-Seq analysis of the liver transcriptome reveals the networks regulating treatment of sitagliptin phosphate plus fuzhujiangtang granule in the zucker diabetic fatty rats. Evid Based Complement Alternat Med. 2020;2020:8463858.
   PubMed Web of Science ®Google Scholar
• Zhao Y, Liu B, He L, et al. A novel classification method for aid decision of traditional Chinese patent medicines for stroke treatment. Front Med. 2017;11(3):432–439.
   PubMed Web of Science ®Google Scholar
• Carta G, Murru E, Banni S, et al. Palmitic acid: physiological role, metabolism and nutritional implications. Front Physiol. 2017;8:902.
   PubMed Web of Science ®Google Scholar
• Bosma M, Kersten S, Hesselink MK, et al. Re-evaluating lipotoxic triggers in skeletal muscle: relating intramyocellular lipid metabolism to insulin sensitivity. Prog Lipid Res. 2012;51(1):36–49.
   PubMed Web of Science ®Google Scholar
• Wang Y, Qin S, Pen G, et al. Original research: potential ocular protection and dynamic observation of polygonatum sibiricum polysaccharide against streptozocin-induced diabetic rats’ model. Exp Biol Med (Maywood). 2017;242(1):92–101.
   PubMed Web of Science ®Google Scholar
• Kiran S, Kumar V, Kumar S, et al. Adipocyte, immune cells, and miRNA crosstalk: a novel regulator of metabolic dysfunction and obesity. Cells. 2021;10(5):1004.
   Web of Science ®Google Scholar
• Tiwari J, Gupta G, de Jesus Andreoli Pinto T, et al. Role of microRNAs (miRNAs) in the pathophysiology of diabetes mellitus. Panminerva Med. 2018;60(1):25–28.
   PubMed Web of Science ®Google Scholar
• Xiao C, Hong H, Yu H, et al. MiR-340 affects gastric cancer cell proliferation, cycle, and apoptosis through regulating SOCS3/JAK-STAT signaling pathway. Immunopharmacol Immunotoxicol. 2018;40(4):278–283.
   PubMed Web of Science ®Google Scholar
• Shuang Y, Liu J, Niu J, et al. A novel circular RNA circPPFIA1 promotes laryngeal squamous cell carcinoma progression through sponging miR-340-3p and regulating ELK1 expression. Bioengineered. 2021;12(1):5220–5230.
   PubMed Web of Science ®Google Scholar
• Che X, Zhao R, Xu H, et al. Differently Expressed Genes (DEGs) relevant to type 2 diabetes mellitus identification and pathway analysis via integrated bioinformatics analysis. Med Sci Monit. 2019;25:9237–9244.
   PubMed Web of Science ®Google Scholar
• Qian L, Xia Z, Zhang M, et al. Integrated bioinformatics-based identification of potential diagnostic biomarkers associated with diabetic foot ulcer development. J Diabetes Res. 2021;2021:5445349.
   PubMed Web of Science ®Google Scholar
• Wesche H, Gao X, Li X, et al. IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family. J Biol Chem. 1999;274(27):19403–19410.
   PubMed Web of Science ®Google Scholar
• Tan Q, Majewska-Szczepanik M, Zhang X, et al. IRAK-M deficiency promotes the development of type 1 diabetes in NOD mice. Diabetes. 2014;63(8):2761–2775.
   PubMed Web of Science ®Google Scholar
• Hulsmans M, Geeraert B, De Keyzer D, et al. Interleukin-1 receptor-associated kinase-3 is a key inhibitor of inflammation in obesity and metabolic syndrome. PLoS One. 2012;7(1):e30414.
   PubMed Web of Science ®Google Scholar