Integral membrane protein 2A enhances sensitivity to chemotherapy via notch signaling pathway in cervical cancer

References

• Zhao M, Huang W, Zou S, et al. A five-genes-based prognostic signature for cervical cancer overall survival prediction. Int J Genomics. 2020;2020:8347639.
   PubMed Web of Science ®Google Scholar
• Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–249.
   PubMed Web of Science ®Google Scholar
• Diaz-Padilla I, Monk BJ, Mackay HJ, et al. Treatment of metastatic cervical cancer: future directions involving targeted agents. Crit Rev Oncol Hematol. 2013;85(3):303–314.
   PubMed Web of Science ®Google Scholar
• Lorusso D, Petrelli F, Coinu A, et al. A systematic review comparing cisplatin and carboplatin plus paclitaxel-based chemotherapy for recurrent or metastatic cervical cancer. Gynecol Oncol. 2014;133(1):117–123.
   PubMed Web of Science ®Google Scholar
• Waks AG, Winer EP. Breast cancer treatment: a review. Jama. 2019;321(3):288–300.
   PubMed Web of Science ®Google Scholar
• Shen DW, Pouliot LM, Hall MD, et al. Cisplatin resistance: a cellular self-defense mechanism resulting from multiple epigenetic and genetic changes. Pharmacol Rev. 2012;64(3):706–721.
   PubMed Web of Science ®Google Scholar
• Lanzi C, Perego P, Supino R, et al. Decreased drug accumulation and increased tolerance to DNA damage in tumor cells with a low level of cisplatin resistance. Biochem Pharmacol. 1998;55(8):1247–1254.
   PubMed Web of Science ®Google Scholar
• Cui Y, Konig J, Buchholz JK, et al. Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells. Mol Pharmacol. 1999;55(5):929–937.
   PubMed Web of Science ®Google Scholar
• Tai TS, Pai SY, Ho IC. Itm2a, a target gene of GATA-3, plays a minimal role in regulating the development and function of T cells. PloS One. 2014;9(5):e96535.
   PubMed Web of Science ®Google Scholar
• Namkoong S, Lee KI, Lee JI, et al. The integral membrane protein ITM2A, a transcriptional target of PKA-CREB, regulates autophagic flux via interaction with the vacuolar ATPase. Autophagy. 2015;11(5):756–768.
   PubMed Web of Science ®Google Scholar
• Park JS, Jeon EK, Chun SH, et al. ERCC1 (excision repair cross-complementation group 1) expression as a predictor for response of neoadjuvant chemotherapy for FIGO stage 2B uterine cervix cancer. Gynecol Oncol. 2011;120(2):275–279.
   PubMed Web of Science ®Google Scholar
• Yu L, Dong L, Wang Y, et al. Reversible regulation of SATB1 ubiquitination by USP47 and SMURF2 mediates colon cancer cell proliferation and tumor progression. Cancer letters 2019 40–51.
   Google Scholar
• Dong L, Yu L, Bai C, et al. USP27-mediated Cyclin E stabilization drives cell cycle progression and hepatocellular tumorigenesis. Oncogene. 2018;37(20):2702–2713.
   PubMed Web of Science ®Google Scholar
• Yu L, Dong L, Li H, et al. Ubiquitination-mediated degradation of SIRT1 by SMURF2 suppresses CRC cell proliferation and tumorigenesis. Oncogene. 2020;39(22):4450–4464.
   PubMed Web of Science ®Google Scholar
• Dong L, Yu L, Li H, et al. An NAD(+)-dependent deacetylase SIRT7 promotes HCC development through deacetylation of USP39. iScience. 2020;23(8):101351.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Shen X. Heat shock protein 27 protects L929 cells from cisplatin-induced apoptosis by enhancing Akt activation and abating suppression of thioredoxin reductase activity. Clin Cancer Res off J Am Assoc Cancer Res. 2007;13(10):2855–2864.
   PubMed Web of Science ®Google Scholar
• Nagy A, Lanczky A, Menyhart O, et al. Validation of miRNA prognostic power in hepatocellular carcinoma using expression data of independent datasets. Sci Rep. 2018;8(1):9227.
   PubMed Web of Science ®Google Scholar
• Yang YH, Dudoit S, Luu P, et al. Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation. Nucleic Acids Res. 2002;30(4):e15.
   PubMed Web of Science ®Google Scholar
• Smyth GK, Speed T. Normalization of cDNA microarray data. Methods. 2003;31(4):265–273.
   PubMed Web of Science ®Google Scholar
• Zhou Y, Zhou B, Pache L, et al. Metascape provides a biologist-oriented resource for the analysis of systems-level datasets. Nat Commun. 2019;10(1):1523.
   PubMed Web of Science ®Google Scholar
• Torre LA, Bray F, Siegel RL, et al. Global cancer statistics, 2012. CA Cancer J Clin. 2015;65(2):87–108.
   PubMed Web of Science ®Google Scholar
• Li Y, Cui N, Zheng PS, et al. BMX/Etk promotes cell proliferation and tumorigenicity of cervical cancer cells through PI3K/AKT/mTOR and STAT3 pathways. Oncotarget. 2017;8(30):49238–49252.
   PubMedGoogle Scholar
• Marquard FE, Jucker M. PI3K/AKT/mTOR signaling as a molecular target in head and neck cancer. Biochem Pharmacol. 2020;172:113729.
   PubMed Web of Science ®Google Scholar
• Zhang HY, Zhang PN, Sun H. Aberration of the PI3K/AKT/mTOR signaling in epithelial ovarian cancer and its implication in cisplatin-based chemotherapy. Eur J Obstet Gynecol Reprod Biol. 2009;146(1):81–86.
   PubMed Web of Science ®Google Scholar
• Duan W, Liu X. PSAT1 upregulation contributes to cell growth and cisplatin resistance in cervical cancer cells via regulating PI3K/AKT signaling pathway. Ann Clin Lab Sci. 2020;50(4):512–518.
   PubMed Web of Science ®Google Scholar
• Chen B, Shen Z, Wu D, et al. Glutathione peroxidase 1 promotes NSCLC resistance to cisplatin via ROS-induced activation of PI3K/AKT pathway. Biomed Res Int. 2019;2019:7640547.
   PubMed Web of Science ®Google Scholar
• Abuderman AA, Harb OA, Gertallah LM. Prognostic and clinicopathological values of tissue expression of MFAP5 and ITM2A in triple-negative breast cancer: an immunohistochemical study. Contemp Oncol. 2020;24(2):87–95.
   Google Scholar
• Nguyen TM, Shin IW, Lee TJ, et al. Loss of ITM2A, a novel tumor suppressor of ovarian cancer through G2/M cell cycle arrest, is a poor prognostic factor of epithelial ovarian cancer. Gynecol Oncol. 2016;140(3):545–553.
   PubMed Web of Science ®Google Scholar
• Zhang R, Xu T, Xia Y, et al. ITM2A as a tumor suppressor and its correlation with PD-L1 in breast cancer. Front Oncol. 2020;10:581733.
   PubMedGoogle Scholar
• Zhou JX, Han JB, Chen SM, et al. gamma-secretase inhibition combined with cisplatin enhances apoptosis of nasopharyngeal carcinoma cells. Exp Ther Med. 2012;3(2):357–361.
   PubMed Web of Science ®Google Scholar