Mechanism of microRNA regulating the progress of atherosclerosis in apoE-deficient mice

References

• Flora GD, Nayak MK. A brief review of cardiovascular diseases, associated risk factors and current treatment regimes. Curr Pharm Des. 2019;25(38):4063–4084.
   PubMed Web of Science ®Google Scholar
• Mozaffarian D, Mozaffarian D, Benjamin EJ, et al. Heart disease and stroke statistics-2016 update: a report from the American Heart Association. Circulation. 2016;133(4):e38–360.
   PubMed Web of Science ®Google Scholar
• Gimbrone MA Jr., Garcia-Cardena G. Endothelial cell dysfunction and the pathobiology of atherosclerosis. Circ Res. 2016;118(4):620–636.
   PubMed Web of Science ®Google Scholar
• Paone S, Baxter AA, Hulett MD, et al. Endothelial cell apoptosis and the role of endothelial cell-derived extracellular vesicles in the progression of atherosclerosis. Cell Mol Life Sci. 2019;76(6):1093–1106.
   PubMed Web of Science ®Google Scholar
• Bories GFP, Leitinger N. Macrophage metabolism in atherosclerosis. FEBS Lett. 2017;591(19):3042–3060.
   PubMed Web of Science ®Google Scholar
• Groh L, Keating ST, Joosten LAB, et al. Monocyte and macrophage immunometabolism in atherosclerosis. Semin Immunopathol. 2018;40(2):203–214.
   PubMed Web of Science ®Google Scholar
• Chistiakov DA, Orekhov AN, Bobryshev YV. Vascular smooth muscle cell in atherosclerosis. Acta Physiol (Oxf). 2015;214(1):33–50.
   PubMed Web of Science ®Google Scholar
• Wang Y, et al. Smooth muscle cells contribute the majority of foam cells in ApoE (Apolipoprotein E)-deficient mouse atherosclerosis. Thromb Vasc Biol Atvbah 2019b;a119312434.
   Google Scholar
• Hurtubise J, McLellan K, Durr K, et al. the different facets of dyslipidemia and hypertension in atherosclerosis current atherosclerosis reports 18:82 hussain MM, Goldberg IJ (2018) Human MicroRNA-33b Promotes Atherosclerosis in Apoe(-/-) Mice. Arterioscler Thromb Vasc Biol. 2016;38:2272–2275.
   Google Scholar
• Koelwyn GJ, Corr EM, Erbay E. Regulation of macrophage immunometabolism in atherosclerosis. Nat Immunol. 2018;19(6):526–537.
   PubMed Web of Science ®Google Scholar
• Low Wang CC, Hess CN, Hiatt WR, et al. Clinical update: cardiovascular disease in diabetes mellitus: atherosclerotic cardiovascular disease and heart failure in type 2 diabetes mellitus - mechanisms, management, and clinical considerations. Circulation. 2016;133(24):2459–2502.
   PubMed Web of Science ®Google Scholar
• Marchio P, Guerra-Ojeda S, Vila JM. Targeting early atherosclerosis: a focus on oxidative stress and inflammation. Oxid Med Cell Longev. 2019;2019:8563845.
   PubMed Web of Science ®Google Scholar
• Shimada K. Immune system and atherosclerotic disease: heterogeneity of leukocyte subsets participating in the pathogenesis of atherosclerosis. Circ J. 2009;73(6):994–1001.
   PubMed Web of Science ®Google Scholar
• Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116(2):281–297.
   PubMed Web of Science ®Google Scholar
• Eastwood J, Caslake MJ, Sodi R. The association of circulating microRNA-30c with atherogenic lipoprotein subfractions and composition Clinica chimica acta. Int J Clin Chem. 2016;462:135–139.
   Google Scholar
• Feinberg MW, Moore KJ. MicroRNA Regulation of Atherosclerosis. Circ Res. 2016;118(4):703–720.
   PubMed Web of Science ®Google Scholar
• Tana C, Giamberardino MA, Cipollone F. microRNA profiling in atherosclerosis, diabetes, and migraine. Ann Med. 2017;49(2):93–105.
   PubMed Web of Science ®Google Scholar
• Wang A, Kwee LC, Grass E, et al. Whole blood sequencing reveals circulating microRNA associations with high-risk traits in non-ST-segment elevation acute coronary syndrome. Atherosclerosis. 2017a;261:19–25.
   PubMed Web of Science ®Google Scholar
• Li Y, Yang N, Dong B, et al. MicroRNA-122 promotes endothelial cell apoptosis by targeting XIAP: therapeutic implication for atherosclerosis. Life Sci. 2019;232:116590.
   PubMed Web of Science ®Google Scholar
• Menghini R, Casagrande V, Marino A, et al. MiR-216a: a link between endothelial dysfunction and autophagy. Cell Death Dis. 2014;5(1):e1029.
   PubMedGoogle Scholar
• Zhao J, Ou SL, Wang WY, et al. MicroRNA-1907 enhances atherosclerosis-associated endothelial cell apoptosis by suppressing Bcl-2. Am J Transl Res. 2017;9(7):3433–3442.
   PubMed Web of Science ®Google Scholar
• Zhu L, Li Q, Qi D, et al. Atherosclerosis-associated endothelial cell apoptosis by miRNA let7-b-mediated downregulation of HAS-2. J Cell Biochem. 2019 Nov;2019:17.
   Google Scholar
• Di Gregoli K, Jenkins N, Salter R, et al. MicroRNA-24 regulates macrophage behavior and retards atherosclerosis. Arterioscler Thromb Vasc Biol. 2014;34(9):1990–2000.
   PubMed Web of Science ®Google Scholar
• Karunakaran D, Rayner KJ. Macrophage miRNAs in atherosclerosis. Biochim Biophys Acta. 2016;1861(1):2087–2093.
   PubMedGoogle Scholar
• Ouimet M, Ediriweera H, Afonso MS, et al. microRNA-33 Regulates Macrophage Autophagy in Atherosclerosis. Arterioscler Thromb Vasc Biol. 2017;37(6):1058–1067.
   PubMed Web of Science ®Google Scholar
• Yang S, et al. MicroRNA-216a promotes M1 macrophages polarization and atherosclerosis progression by activating telomerase via the Smad3/NF-kappaB pathway. Biochim Biophys Acta Mol Basis Dis. 2019;1865(7):1772–1781.
   PubMed Web of Science ®Google Scholar
• Alshanwani AR, Riches-Suman K, O’Regan DJ, et al. MicroRNA-21 drives the switch to a synthetic phenotype in human saphenous vein smooth muscle cells. IUBMB Life. 2018;70(7):649–657.
   PubMed Web of Science ®Google Scholar
• Liu H, Xiong W, Liu F, et al. Dong S(2019b) MicroRNA-133b regulates the growth and migration of vascular smooth muscle cells by targeting matrix metallopeptidase 9. Pathol Res Pract. 2019;215(5):1083–1088.
   PubMed Web of Science ®Google Scholar
• Sun Y, Gao Y, Song T, et al. MicroRNA-15b participates in the development of peripheral arterial disease by modulating the growth of vascular smooth muscle cells. Exp Ther Med. 2019;18(1):77–84.
   PubMed Web of Science ®Google Scholar
• Xing T, Du L, Zhuang X, et al. Upregulation of microRNA-206 induces apoptosis of vascular smooth muscle cells and decreases risk of atherosclerosis through modulating FOXP1. Exp Ther Med. 2017;14(5):4097–4103.
   PubMed Web of Science ®Google Scholar
• Zahedi F, et al. Dicer generates a regulatory microRNA network in smooth muscle cells that limits neointima formation during vascular repair. Cell Mol Life Sci. 2017;74(2):359–372.
   PubMed Web of Science ®Google Scholar
• Ren K, Zhu X, Zheng Z, et al. MicroRNA-24 aggravates atherosclerosis by inhibiting selective lipid uptake from HDL cholesterol via the post-transcriptional repression of scavenger receptor class B type I. Atherosclerosis. 2018;270:57–67.
   PubMed Web of Science ®Google Scholar
• Sahebkar A, Watts GF. Developing role of microRNA-33 in lipid metabolism and atherosclerosis. Curr Opin Lipidol. 2016;27(2):197–199.
   PubMed Web of Science ®Google Scholar
• Tan L, Liu L, Jiang Z, et al. Inhibition of microRNA-17-5p reduces the inflammation and lipid accumulation, and up-regulates ATP-binding cassette transporterA1 in atherosclerosis. J Pharmacol Sci. 2019;139(4):280–288.
   PubMed Web of Science ®Google Scholar
• Han H, Wang Y-H, Qu G-J, et al. Differentiated miRNA expression and validation of signaling pathways in apoE gene knockout mice by cross-verification microarray platform. Exp Mol Med. 2013;45(3):e13.
   PubMedGoogle Scholar
• Zhen S, Yao C, Li Z-L, et al. Differentially expressed microRNAs at different stages of atherosclerosis in ApoE-deficient mice. Chin Med J (Engl). 2013;126(3):515–520.
   PubMed Web of Science ®Google Scholar
• Virtue A, Johnson C, Lopez-Pastraña J, et al. MicroRNA-155 deficiency leads to decreased atherosclerosis, increased white adipose tissue obesity, and non-alcoholic fatty liver disease: a NOVEL MOUSE MODEL OF OBESITY PARADOX. J Biol Chem. 2017;292(4):1267–1287.
   PubMed Web of Science ®Google Scholar
• Jing R, Zhong QQ, Long TY, et al. Downregulated miRNA-26a-5p induces the apoptosis of endothelial cells in coronary heart disease by inhibiting PI3K/AKT pathway. Eur Rev Med Pharmacol Sci. 2019;23(11):4940–4947.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Ma X, Li X, et al. Effects of icariin on atherosclerosis and predicted function regulatory network in apoe deficient mice. Biomed Res Int. 2018b;2018:9424186.
   PubMed Web of Science ®Google Scholar
• Lin Y, Bai L, Chen Y, et al. Liu E(2015) Practical assessment of the quantification of atherosclerotic lesions in apoE‑/‑mice. Mol Med Rep. 2015;12(4):5298–5306.
   PubMed Web of Science ®Google Scholar
• Papadaki C, Monastirioti A, Rounis K, et al. Circulating MicroRNAs regulating DNA damage response and responsiveness to cisplatin in the prognosis of patients with non-small cell lung cancer treated with first-line platinum chemotherapy. Cancers (Basel). 2020;12(5):1282.
   PubMed Web of Science ®Google Scholar
• Agarwal V, Bell GW, Nam JW, et al. (2015) Predicting effective microRNA target sites in mammalian mRNAs Elife 4
   Google Scholar
• Betel D, Wilson M, Gabow A, et al. The microRNA.org resource: targets and expression. Nucleic Acids Res. 2008;36(Database):D149–153.
   PubMed Web of Science ®Google Scholar
• Lydersen S, Laake P. Power comparison of two-sided exact tests for association in 2 × 2 contingency tables using standard, midp and randomized test versions. Stat Med. 2003;22(24):172643–172671.
   PubMed Web of Science ®Google Scholar
• McHugh ML. The chi-square test of Independence. Biochem Med (Zagreb). 2013;23(2):143–149.
   PubMed Web of Science ®Google Scholar
• Mishra P, Singh U, Pandey CM, et al. Application of student’s t-test, analysis of variance, and covariance. Ann Card Anaesth. 2019;22(4):407–411.
   PubMed Web of Science ®Google Scholar
• Getz GS, Reardon CA. Diet and murine atherosclerosis. Arterioscler Thromb Vasc Biol. 2006;26(2):242–249.
   PubMed Web of Science ®Google Scholar
• Getz GS, Reardon CA. Diet, microbes, and murine atherosclerosis. Arterioscler Thromb Vasc Biol. 2018;38(10):2269–2271.
   PubMed Web of Science ®Google Scholar
• Chipont A, Esposito B, Challier I, et al. MicroRNA-21 deficiency alters the survival of Ly-6C lo monocytes in ApoE -/- mice and reduces early-stage Atherosclerosis—Brief Report. Arterioscler Thromb Vasc Biol. 2019;39(2):170–177.
   PubMed Web of Science ®Google Scholar
• Ye Y, Zhao X, Lu Y, et al. Varinostat Alters Gene Expression Profiles in Aortic Tissues from ApoE-/–Mice. Ther Clin Dev. 2018;29(4):214–225
   PubMed Web of Science ®Google Scholar
• Yerlikaya FH, Ö M. Aberrant expression of miRNA profiles in high-fat and high-sucrose fed rats. Clin Nutr Exp. 2019;27:1–8.
   Google Scholar
• Chen H, Guo X, Xiao X, et al. Identification and functional characterization of microRNAs in rat Leydig cells during development from the progenitor to the adult stage. Mol Cell Endocrinol. 2019;493:110453.
   PubMed Web of Science ®Google Scholar
• Pardo PS, Hajira A, Boriek AM, et al. MicroRNA-434-3p regulates age-related apoptosis through eIF5A1 in the skeletal muscle. Aging (Albany NY). 2017;9(3):1012–1029.
   PubMedGoogle Scholar
• Feng H, Wu J, Chen P, et al. MicroRNA-375-3p inhibitor suppresses angiotensin II-induced cardiomyocyte hypertrophy by promoting lactate dehydrogenase B expression. J Cell Physiol. 2019;234(8):14198–14209.
   PubMed Web of Science ®Google Scholar
• Fu Q, Jiang H, Wang Z, et al. Injury factors alter miRNAs profiles of exosomes derived from islets and circulatio. Aging (Albany NY). 2018;10(12):3986–3999.
   PubMedGoogle Scholar
• Knudsen LA, Petersen N, Schwartz TW, et al. The MicroRNA repertoire in enteroendocrine cells: identification of miR-375 as a potential regulator of the enteroendocrine lineage. Endocrinology. 2015;156(11):3971–3983.
   PubMed Web of Science ®Google Scholar
• Sun T, Li CT, Xiong L, et al. miR-375-3p negatively regulates osteogenesis by targeting and decreasing the expression levels of LRP5 and beta-catenin. PLoS One. 2017;12:e0171281.
   PubMed Web of Science ®Google Scholar
• Hu YW, Zhao J-Y, Li S-F, et al. RP5-833A20.1/miR-382-5p/NFIA-dependent signal transduction pathway contributes to the regulation of cholesterol homeostasis and inflammatory reaction. Arterioscler Thromb Vasc Biol. 2015;35(1):87–101.
   PubMed Web of Science ®Google Scholar
• Wang J, Chen C, Yan X, et al. The role of miR-382-5p in glioma cell proliferation, migration and invasion. Onco Targets Ther. 2019a;261:4993–5002.
   Google Scholar
• Zheng S, Li M, Miao K, et al. SNHG1 contributes to proliferation and invasion by regulating miR-382 in breast cancer. Cancer Manag Res. 2019;11:5589–5598.
   PubMed Web of Science ®Google Scholar
• He Q, Zhao L, Liu X, et al. MOV10 binding circ-DICER1 regulates the angiogenesis of glioma via miR-103a-3p/miR-382-5p mediated ZIC4 expression change. J Exp Clin Cancer Res. 2019b;38(1):9.
   PubMedGoogle Scholar
• Rossi C, Zini R, Rontauroli S. Role of TGF-β1/miR-382-5p/SOD2 axis in the induction of oxidative stress in CD 34+ cells from primary myelofibrosis. Mol Oncol. 2018;12(12):2102–2123.
   PubMed Web of Science ®Google Scholar
• Li Y, Xiao L, Li J, et al. MicroRNA profiling of diabetic atherosclerosis in a rat model. Eur J Med Res. 2018;23(1):55.
   PubMedGoogle Scholar
• Chen JS, Huang JQ, Dong SH, et al. [Effects of microRNA-379-5p on proliferation, migration and invasion of hepatocellular carcinoma cell line]. Zhonghua Yi Xue Za Zhi. 2016;96(18):1450–1453.
   PubMedGoogle Scholar
• He Q, Fang Y, Lu F. Analysis of differential expression profile of miRNA in peripheral blood of patients with lung cancer. J Clin Lab Anal. 2019a;33(9):e23003.
   PubMed Web of Science ®Google Scholar
• Lv X, Wang M, Qiang J, et al. Circular RNA circ-PITX1 promotes the progression of glioblastoma by acting as a competing endogenous RNA to regulate miR-379-5p/MAP3K2 axis. Eur J Pharmacol. 2019;863:172643.
   PubMed Web of Science ®Google Scholar
• Xu X, Wang Y, Mojumdar K, et al. A-to-I-edited miRNA-379-5p inhibits cancer cell proliferation through CD97-induced apoptosis. J Clin Invest. 2019;129(12):5343–5356.
   PubMed Web of Science ®Google Scholar
• Gao ZF, Ji XL, Gu J, et al. microRNA-107 protects against inflammation and endoplasmic reticulum stress of vascular endothelial cells via KRT1-dependent Notch signaling pathway in a mouse model of coronary atherosclerosis. J Cell Physiol. 2019;234(7):12029–12041.
   PubMed Web of Science ®Google Scholar
• Hao XZ, Fan HM. Identification of miRNAs as atherosclerosis biomarkers and functional role of miR-126 in atherosclerosis progression through MAPK signalling pathway. Eur Rev Med Pharmacol Sci. 2017;21(11):2725–2733.
   PubMed Web of Science ®Google Scholar
• Tang F, Yang TL. MicroRNA-126 alleviates endothelial cells injury in atherosclerosis by restoring autophagic flux via inhibiting of PI3K/Akt/mTOR pathway. Biochem Biophys Res Commun. 2018;495(1):1482–1489.
   PubMed Web of Science ®Google Scholar
• Wang Y, Han Z, Fan Y, et al. MicroRNA-9 Inhibits NLRP3 inflammasome activation in human atherosclerosis inflammation cell models through the JAK1/STAT signaling pathway. Cell Physiol Biochem. 2017b;41(4):1555–1571.
   PubMedGoogle Scholar
• Zhang Y, Jia L, Ji W, et al. MicroRNA-141 inhibits the proliferation of penile cavernous smooth muscle cells associated with down-regulation of the rhoa/rho kinase signaling pathway. Cell Physiol Biochem. 2018a;48(1):348–360.
   PubMedGoogle Scholar
• Liu D, Zhong L, Yuan Z, et al. Liu B(2019a) miR-382-5p modulates the ATRA-induced differentiation of acute promyelocytic leukemia by targeting tumor suppressor PTEN. Cell Signal. 2019;54:1–9.
   PubMed Web of Science ®Google Scholar
• Shang FF, Xia QJ, Liu W, et al. miR-434-3p and DNA hypomethylation co-regulate eIF5A1 to increase AChRs and to improve plasticity in SCT rat skeletal muscle. Sci Rep. 2016;6(1):22884.
   PubMedGoogle Scholar