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Research Paper

Inhibition of integrin subunit alpha 11 restrains gastric cancer progression through phosphatidylinositol 3-kinase/Akt pathway

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Pages 11909-11921 | Received 17 Sep 2021, Accepted 09 Nov 2021, Published online: 19 Dec 2021

References

  • Song Z, Wu Y, Yang J, et al. Progress in the treatment of advanced gastric cancer. Tumour Biol. 2017 Jul;39(7):1010428317714626.
  • Ang TL, Fock KM. Clinical epidemiology of gastric cancer. Singapore Med J. 2014 Dec;55(12):621–628.
  • Johnston FM, Beckman M. Updates on Management of Gastric Cancer. Curr Oncol Rep. 2019 Jun 24;21(8):67.
  • Petryszyn P, Chapelle N, Matysiak-Budnik T. Gastric Cancer: where Are We Heading? Dig Dis. 2020;38(4):280–285. Epub 2020 Feb 17.
  • Bianconi D, Unseld M, Prager GW. Integrins in the Spotlight of Cancer. Int J Mol Sci. 2016 Dec 6;17(12):2037.
  • Pan Y, Liu G, Yuan Y, et al. Analysis of differential gene expression profile identifies novel biomarkers for breast cancer. Oncotarget. 2017 Dec 8;8(70):114613–114625.
  • Wu P, Wang Y, Wu Y, et al. Expression and prognostic analyses of ITGA11, ITGB4 and ITGB8 in human non-small cell lung cancer. PeerJ. 2019;7:e8299.
  • Ando T, Kage H, Matsumoto Y, et al. Integrin α11 in non-small cell lung cancer is associated with tumor progression and postoperative recurrence. Cancer Sci. 2020Jan;1112:200–208. Epub 2019 Dec 18
  • Pompura SL, Dominguez-Villar M. The PI3K/AKT signaling pathway in regulatory T-cell development, stability, and function. J Leukoc Biol. 2018 Jan 22. 10.1002/JLB.2MIR0817-349R. Epub ahead of print.
  • Shorning BY, Dass MS, Smalley MJ, et al. The PI3K-AKT-mTOR Pathway and Prostate Cancer: at the Crossroads of AR, MAPK, and WNT Signaling. Int J Mol Sci. 2020 Jun 25;21(12):4507.
  • Slomovitz BM, Coleman RL. The PI3K/AKT/mTOR pathway as a therapeutic target in endometrial cancer. Clin Cancer Res. 2012Nov1;18(21):5856–5864. Epub 2012 Oct 18.
  • Jiang T, Zhou ML, Fan J. Inhibition of GLUT-1 expression and the PI3K/Akt pathway to enhance the chemosensitivity of laryngeal carcinoma cells in vitro. Onco Targets Ther. 2018 Nov 6;11: 7865–7872.
  • Jiang C, Ma Z, Zhang G, et al. CSNK2A1 Promotes Gastric Cancer Invasion Through the PI3K-Akt-mTOR Signaling Pathway. Cancer Manag Res. 2019;11:10135–10143.
  • Zhao H, Xu J, Wang Y, et al. Knockdown of CEACAM19 suppresses human gastric cancer through inhibition of PI3K/Akt and NF-κB. Surg Oncol. 2018Sep;273:495–502. Epub 2018 May 3
  • Binsila BK, Selvaraju S, Ghosh SK, et al. EGF, GDNF, and IGF-1 influence the proliferation and stemness of ovine spermatogonial stem cells in vitro. J Assist Reprod Genet. 2020;37(10):2615–2630.
  • Zhu Q, Li Y, Li L, et al. MicroRNA-889-3p restrains the proliferation and epithelial-mesenchymal transformation of lung cancer cells via down-regulation of Homeodomain-interacting protein kinase 1 [published online ahead of print, 2021 Nov 1]. Bioengineered 2021. 10.1080/21655979.2021.2000283.
  • Zhang N, Liu JF. MicroRNA (MiR)-301a-3p regulates the proliferation of esophageal squamous cells via targeting PTEN. Bioengineered. 2020;11(1):972–983.
  • Tang Y, Li Y, Xin D, et al. Icariin alleviates osteoarthritis by regulating autophagy of chondrocytes by mediating PI3K/AKT/mTOR signaling. Bioengineered. 2021;12(1):2984–2999.
  • Zhao J, Zhou K, Ma L, et al. MicroRNA-145 overexpression inhibits neuroblastoma tumorigenesis in vitro and in vivo. Bioengineered. 2020;11(1):219–228.
  • Ning L, Zhang M, Zhu Q, et al. miR-25-3p inhibition impairs tumorigenesis and invasion in gastric cancer cells in vitro and in vivo. Bioengineered. 2020;11(1):81–90.
  • Smyth EC, Nilsson M, Grabsch HI, et al. Gastric cancer. Lancet. 2020 Aug 29;396(10251):635–648.
  • Tiger CF, Fougerousse F, Grundström G, et al. alpha11beta1 integrin is a receptor for interstitial collagens involved in cell migration and collagen reorganization on mesenchymal nonmuscle cells. Dev Biol. 2001 Sep 1;237(1):116–129.
  • Talior-Volodarsky I, Connelly KA, Arora PD, et al. α11 integrin stimulates myofibroblast differentiation in diabetic cardiomyopathy. Cardiovasc Res. 2012Nov1;96(2):265–275. Epub 2012 Aug 6.
  • Li Z, Jia J, Gou J, et al. Mmu-miR-126a-3p plays a role in murine embryo implantation by regulating Itga11. Reprod Biomed Online. 2015Sep;313:384–393. Epub 2015 Jun 4
  • Mao Z, Wu F, Shan Y. Identification of key genes and miRNAs associated with carotid atherosclerosis based on mRNA-seq data. Medicine (Baltimore). 2018 Mar;97(13):e9832.
  • Guo SM, Wang JX, Li J, et al. Identification of gene expression profiles and key genes in subchondral bone of osteoarthritis using weighted gene expression network analysis. J Cell Biochem. 2018Sep;1199:7687–7695. Epub 2018 Jun 15
  • Shin J, Shim HG, Hwang T, et al. Restoration of miR-29b exerts anti-cancer effects on glioblastoma. Cancer Cell Int. 2017;17:104.
  • Ju JA, Godet I, Ye IC, et al. Hypoxia Selectively Enhances Integrin α5β1 Receptor Expression in Breast Cancer to Promote Metastasis. Mol Cancer Res. 2017Jun;156:723–734. Epub 2017 Feb 17
  • Parajuli H, Teh MT, Abrahamsen S, et al. Integrin α11 is overexpressed by tumour stroma of head and neck squamous cell carcinoma and correlates positively with alpha smooth muscle actin expression. J Oral Pathol Med. 2017Apr;464:267–275. Epub 2016 Oct 4
  • Zhao C, Tao T, Yang L, et al. Loss of PDZK1 expression activates PI3K/AKT signaling via PTEN phosphorylation in gastric cancer. Cancer Lett. 2019 Jul 1;453:107–121. Epub 2019 Mar 29.
  • Zeng L, Liao Q, Zou Z, et al. Long Non-Coding RNA XLOC_006753 Promotes the Development of Multidrug Resistance in Gastric Cancer Cells Through the PI3K/AKT/mTOR Signaling Pathway. Cell Physiol Biochem. 2018;51(3):1221–1236. Epub 2018 Nov 27.
  • Ni SJ, Zhao LQ, Wang XF, et al. CBX7 regulates stem cell-like properties of gastric cancer cells via p16 and AKT-NF-κB-miR-21 pathways. J Hematol Oncol. 2018 Feb 8;11(1):17.
  • Wang G, Lu M, Yao Y, et al. Esculetin exerts antitumor effect on human gastric cancer cells through IGF-1/PI3K/Akt signaling pathway. Eur J Pharmacol. 2017 Nov 5;814:207–215. Epub 2017 Aug 25.
  • Wang J, Zhang Y, Dou Z, et al. Knockdown of STIL suppresses the progression of gastric cancer by down-regulating the IGF-1/PI3K/AKT pathway. J Cell Mol Med. 2019Aug;238:5566–5575. Epub 2019 Jun 11