2,011
Views
4
CrossRef citations to date
0
Altmetric
Research Paper

MiR-455-5p upregulation in umbilical cord mesenchymal stem cells attenuates endometrial injury and promotes repair of damaged endometrium via Janus kinase/signal transducer and activator of transcription 3 signaling

ORCID Icon, , , , &
Pages 12891-12904 | Received 30 Sep 2021, Accepted 12 Nov 2021, Published online: 14 Dec 2021

References

  • Zhang H, Zhang Q, Zhang J, et al. Urinary bladder matrix scaffolds improve endometrial regeneration in a rat model of intrauterine adhesions. Biomater Sci. 2020 Feb 7;8(3):988–996.
  • Kou L, Jiang X, Xiao S, et al. Therapeutic options and drug delivery strategies for the prevention of intrauterine adhesions. J Control Release. 2020 Feb;318:25–37.
  • Park M, Hong SH, Park SH, et al. Perivascular Stem cell-derived cyclophilin a improves uterine environment with asherman’s syndrome via HIF1α-dependent angiogenesis. Mol Ther. 2020 Aug 5;28(8):1818–1832.
  • Hanstede MM, van der Meij E, Goedemans L, et al. Results of centralized Asherman surgery, 2003-2013. Fertil Steril. 2015 Dec;104(6):1561–8.e1.
  • Chason RJ, Levens ED, Yauger BJ, et al. Balloon fluoroscopy as treatment for intrauterine adhesions: a novel approach. Fertil Steril. 2008 Nov;90(5):2005.e15–7.
  • Leprince S, Huberlant S, Allegre L, et al. Preliminary design of a new degradable medical device to prevent the formation and recurrence of intrauterine adhesions. Commun Biol. 2019;2:196.
  • Beerts C, Brondeel C, Pauwelyn G, et al. Scintigraphic tracking of (99m)Technetium-labelled equine peripheral blood-derived mesenchymal stem cells after intravenous, intramuscular, and subcutaneous injection in healthy dogs. Stem Cell Res Ther. 2021 Jul 13;12(1):393.
  • Ling-Ling E, Cheng T, Li CJ, et al. Combined use of recombinant human BMP-7 and osteogenic media may have No ideal synergistic effect on leporine bone regeneration of human umbilical cord mesenchymal stem cells seeded on nanohydroxyapatite/collagen/poly (l-Lactide). Stem Cells Dev. 2020 Sep 15;29(18):1215–1228.
  • Lanzoni G, Linetsky E, Correa D, et al. Umbilical cord mesenchymal stem cells for COVID-19 acute respiratory distress syndrome: a double-blind, phase 1/2a, randomized controlled trial. Stem Cells Transl Med. 2021 May;10(5):660–673.
  • Reyhani S, Abbaspanah B, Mousavi SH. Umbilical cord-derived mesenchymal stem cells in neurodegenerative disorders: from literature to clinical practice. Regen Med. 2020 Apr;15(4):1561–1578.
  • Wang S, Shi C, Cai X, et al. Human acellular amniotic matrix with previously seeded umbilical cord mesenchymal stem cells restores endometrial function in a rat model of injury. Mediators Inflamm. 2021;2021:5573594.
  • Zhang L, Li Y, Guan CY, et al. Therapeutic effect of human umbilical cord-derived mesenchymal stem cells on injured rat endometrium during its chronic phase. Stem Cell Res Ther. 2018 Feb 13;9(1):36.
  • Zhang Y, Shi L, Lin X, et al. Unresponsive thin endometrium caused by Asherman syndrome treated with umbilical cord mesenchymal stem cells on collagen scaffolds: a pilot study. Stem Cell Res Ther. 2021 Jul 22;12(1):420.
  • Cui L, Xu F, Jiang Z, et al. Melatonin regulates proliferation and apoptosis of endometrial stromal cells via MT1. Acta Biochim Biophys Sin (Shanghai). 2021 Oct 12;53(10):1333–1341.
  • Tamura I, Fujimura T, Doi-Tanaka Y, et al. The essential glucose transporter GLUT1 is epigenetically upregulated by C/EBPβ and WT1 during decidualization of the endometrium. J Biol Chem. 2021 Aug 31;297(4):101150.
  • Wang P, Zhou Y, Richards AM. Effective tools for RNA-derived therapeutics: siRNA interference or miRNA mimicry. Theranostics. 2021;11(18):8771–8796.
  • Cervena K, Novosadova V, Pardini B, et al. Analysis of microRNA expression changes during the course of therapy in rectal cancer patients. Front Oncol. 2021;11:702258.
  • Ai Y, Chen M, Liu J, et al. lncRNA TUG1 promotes endometrial fibrosis and inflammation by sponging miR-590-5p to regulate Fasl in intrauterine adhesions. Int Immunopharmacol. 2020 Sep;86:106703.
  • Ning J, Zhang H, Yang H. MicroRNA‑326 inhibits endometrial fibrosis by regulating TGF‑β1/Smad3 pathway in intrauterine adhesions. Mol Med Rep. 2018 Aug;18(2):2286–2292.
  • Mao YY, Su C, Fang CC, et al. Clinical significance of the serum miR-455-5p expression in patients with neonatal sepsis. Bioengineered. 2021 Dec;12(1):4174–4182.
  • Zhang X, Liu Y, Zhao J, et al. MiR-455-5p serves as a biomarker of atherosclerosis and inhibits vascular smooth muscle cell proliferation and migration. Per Med. 2021 May;18(3):213–221.
  • Liu S, Huang X, Liu Y, et al. Functional analysis of miRNAs combined with TGF-β1/Smad3 inhibitor in an intrauterine rat adhesion cell model. Mol Cell Biochem. 2020 Jul;470(1–2):15–28.
  • Chen P, Miao Y, Yan P, et al. MiR-455-5p ameliorates HG-induced apoptosis, oxidative stress and inflammatory via targeting SOCS3 in retinal pigment epithelial cells. J Cell Physiol. 2019 Dec;234(12):21915–21924.
  • Li W, Qi N, Wang S, et al. miR-455-5p regulates atrial fibrillation by targeting suppressor of cytokines signaling 3. J Physiol Biochem. 2021 Aug;77(3):481–490.
  • Yin Y, Liu W, Dai Y. SOCS3 and its role in associated diseases. Hum Immunol. 2015 Oct;76(10):775–780.
  • Martino N, Ramos RB, Lu S, et al. Endothelial SOCS3 maintains homeostasis and promotes survival in endotoxemic mice. JCI Insight. 2021 Jul 22;6(14). DOI:10.1172/jci.insight.147280.
  • Liu J, Shang B, Bai J. IL-22/IL-22R1 promotes proliferation and collagen synthesis of MRC-5 cells via the JAK/STAT3 signaling pathway and regulates airway subepithelial fibrosis. Exp Ther Med. 2020 Sep;20(3):2148–2156.
  • Singh R, Kaundal RK, Zhao B, et al. Resistin induces cardiac fibroblast-myofibroblast differentiation through JAK/STAT3 and JNK/c-Jun signaling. Pharmacol Res. 2021 May;167:105414.
  • Yang L, Han B, Zhang M, et al. Activation of BK channels prevents hepatic stellate cell activation and liver fibrosis through the suppression of TGFβ1/SMAD3 and JAK/STAT3 profibrotic signaling pathways. Front Pharmacol. 2020;11:165.
  • Mushahary D, Spittler A, Kasper C, et al. Isolation, cultivation, and characterization of human mesenchymal stem cells. Cytometry A. 2018 Jan;93(1):19–31.
  • Yao Y, Chen R, Wang G, et al. Exosomes derived from mesenchymal stem cells reverse EMT via TGF-β1/Smad pathway and promote repair of damaged endometrium. Stem Cell Res Ther. 2019 Jul 29;10(1):225.
  • Lv CX, Duan H, Wang S, et al. Exosomes derived from human umbilical cord mesenchymal stem cells promote proliferation of allogeneic endometrial stromal cells. Reprod Sci. 2020 Jun;27(6):1372–1381.
  • Zheng P, Bin H, Chen W. Inhibition of microRNA-103a inhibits the activation of astrocytes in hippocampus tissues and improves the pathological injury of neurons of epilepsy rats by regulating BDNF. Cancer Cell Int. 2019;19:109.
  • Hackethal J, Weihs A, Karner L, et al. Novel human placenta-based extract for vascularization strategies in tissue engineering. Tissue Eng Part C Methods. 2021. DOI:10.1089/ten.TEC.2021.0173.
  • Zhang H, Zhang B, Chen C, et al. Circular RNA circLIFR regulates the proliferation, migration, invasion and apoptosis of human vascular smooth muscle cells via the miR-1299/KDR axis. Metab Brain Dis. 2021. DOI:10.1007/s11011-021-00853-x.
  • Ahmad I, Irfan S, Ali Beg M, et al. The SMAC mimetic AT-101 exhibits anti-tumor and anti-metastasis activity in lung adenocarcinoma cells by the IAPs/ caspase-dependent apoptosis and p65-NFƙB cross-talk. Phytomedicine. 2021;24(7):969–977.
  • Liu S, Sun Y, Hou Y, et al. A novel lncRNA ROPM-mediated lipid metabolism governs breast cancer stem cell properties. J Hematol Oncol. 2021;14(1):178.
  • Li B, Zhang Q, Sun J, et al. Human amniotic epithelial cells improve fertility in an intrauterine adhesion mouse model. Stem Cell Res Ther. 2019 Aug 14;10(1):257.
  • Chen JX, Yi XJ, Gu PL, et al. The role of KDR in intrauterine adhesions may involve the TGF-β1/Smads signaling pathway. Braz J Med Biol Res. 2019;52(10):e8324.
  • Jiang Q, Feng X, Liu D, et al. Pressing intervention promotes the skeletal muscle repair of traumatic myofascial trigger points in rats. J Pain Res. 2021;14:3267–3278.
  • Liu S, Zhong Z, Yi W, et al. Effect of hyperthermic intraperitoneal perfusion chemotherapy combined with radical surgery and capecitabine on stage III gallbladder cancer. Can J Gastroenterol Hepatol. 2021;2021:4006786.
  • Chen X, Zhou Y, Sun Y, et al. Transplantation of decellularized and lyophilized amniotic membrane inhibits endometrial fibrosis by regulating connective tissue growth factor and tissue inhibitor of matrix metalloproteinase-2. Exp Ther Med. 2021 Sep;22(3):968.
  • Salama N, Zaghlol S, Mohamed H, et al. Suppression of the inflammation and fibrosis in Asherman syndrome rat model by mesenchymal stem cells: histological and immunohistochemical studies. Folia Histochem Cytobiol. 2020;58(3):208–218.
  • Sabry D, Mostafa A, Marzouk S, et al. Neupogen and mesenchymal stem cells are the novel therapeutic agents in regeneration of induced endometrial fibrosis in experimental rats. Biosci Rep. 2017;37(5). DOI:10.1042/BSR20170794.
  • Bi ZM, Zhou QF, Geng Y, et al. Human umbilical cord mesenchymal stem cells ameliorate experimental cirrhosis through activation of keratinocyte growth factor by suppressing microRNA-199. Eur Rev Med Pharmacol Sci. 2016 Dec;20(23):4905–4912.
  • Špringer T, Krejčík Z, Homola J. Detecting attomolar concentrations of microRNA related to myelodysplastic syndromes in blood plasma using a novel sandwich assay with nanoparticle release. Biosens Bioelectron. 2021 Dec 15;194:113613.
  • Zheng J, He Q, Tang H, et al. Overexpression of miR-455-5p affects retinol (vitamin A) absorption by downregulating STRA6 in a nitrofen-induced CDH with lung hypoplasia rat model. Pediatr Pulmonol. 2020 Jun;55(6):1433–1439.
  • Chi K, Zhang J, Sun H, et al. Knockdown of lncRNA HOXA-AS3 suppresses the progression of atherosclerosis via sponging miR-455-5p. Drug Des Devel Ther. 2020;14:3651–3662.
  • Prompsy PB, Toubia J, Gearing LJ, et al. Making use of transcription factor enrichment to identify functional microRNA-regulons. Comput Struct Biotechnol J. 2021;19:4896–4903.
  • Ogata H, Chinen T, Yoshida T, et al. Loss of SOCS3 in the liver promotes fibrosis by enhancing STAT3-mediated TGF-beta1 production. Oncogene. 2006 Apr 20;25(17):2520–2530.
  • Wang H, Fu Y. NR1D1 suppressed the growth of ovarian cancer by abrogating the JAK/STAT3 signaling pathway. BMC Cancer. 2021 Jul 30;21(1):871.