MYC-mediated miR-320a affects receptor activator of nuclear factor κB ligand (RANKL)-induced osteoclast formation by regulating phosphatase and tensin homolog (PTEN)

References

• Johnston C B, Dagar M.Osteoporosis in older adults. Med Clin North Am. 2020;104(5):873–884. PubMed PMID: 32773051.
   PubMed Web of Science ®Google Scholar
• Ensrud KE, Crandall CJ.Osteoporosis. Ann Intern Med. 2017;167(3):ITC17–ITC32. PubMed PMID: 28761958.
   PubMed Web of Science ®Google Scholar
• Khosla S, Hofbauer LC.Osteoporosis treatment: recent developments and ongoing challenges.Lancet Diabetes Endocrinol.2017;5(11):898–907; Epub 2017/ 07/12. PubMed PMID: 28689769; PubMed Central PMCID: PMCPMC5798872;
   PubMed Web of Science ®Google Scholar
• Kling JM, Clarke BL, Sandhu NP.Osteoporosis prevention, screening, and treatment: a review.J Womens Health (Larchmt).2014;23(7):563–572; Epub 2014/ 04/29. PubMed PMID: 24766381; PubMed Central PMCID: PMCPMC4089021;
   PubMed Web of Science ®Google Scholar
• Chen X, Wang Z, Duan N, et al. Osteoblast-osteoclast interactions. Connect Tissue Res. 2018;59(2):99–107. PubMed PMID: 28324674; PubMed Central PMCID: PMCPMC5612831.
   PubMed Web of Science ®Google Scholar
• Kim JM, Lin C, Stavre Z, et al. Osteoblast-osteoclast communication and bone homeostasis. Cells. 2020;9(9):2073. PubMed PMID: 32927921; PubMed Central PMCID: PMCPMC7564526.
   PubMed Web of Science ®Google Scholar
• Lacey DL, Timms E, Tan HL, et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell. 1998;93(2):165–176. PubMed PMID: 9568710.
   PubMed Web of Science ®Google Scholar
• Imangali N, Phan QT, Mahady G, et al. The dietary anthocyanin delphinidin prevents bone resorption by inhibiting Rankl-induced differentiation of osteoclasts in a medaka (Oryzias latipes) model of osteoporosis. J Fish Biol. 2021;98(4):1018–1030. PubMed PMID: 32155282.
   PubMed Web of Science ®Google Scholar
• Dang CV.MYC on the path to cancer.Cell.2012;149(1):22–35; Epub 2012/ 04/03. PubMed PMID: 22464321; PubMed Central PMCID: PMCPMC3345192;
   PubMed Web of Science ®Google Scholar
• Park-Min KH, Lim E, Lee MJ, et al. Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation. Nat Commun. 2014;5:5418. Epub 2014/ 11/14. PubMed PMID: 25391636; PubMed Central PMCID: PMCPMC4249944.
   PubMed Web of Science ®Google Scholar
• Bae S, Lee MJ, Mun SH, et al. MYC-dependent oxidative metabolism regulates osteoclastogenesis via nuclear receptor ERRα. J Clin Invest. 2017;127(7):2555–2568. Epub 2017/ 05/23. PubMed PMID: 28530645; PubMed Central PMCID: PMCPMC5490751
   PubMed Web of Science ®Google Scholar
• Yang Y, Yujiao W, Fang W, et al. The roles of miRNA, lncRNA and circRNA in the development of osteoporosis. Biol Res. 2020;53(1):40. PubMed PMID: 32938500; PubMed Central PMCID: PMCPMC7493179.
   PubMed Web of Science ®Google Scholar
• De Martinis M, Ginaldi L, Allegra A, et al. The osteoporosis/microbiota linkage: the role of miRNA. Int J Mol Sci. 2020;21(23):8887. PubMed PMID: 33255179; PubMed Central PMCID: PMCPMC7727697.
   PubMed Web of Science ®Google Scholar
• Wang CG, Hu YH, Su SL, et al. LncRNA DANCR and miR-320a suppressed osteogenic differentiation in osteoporosis by directly inhibiting the Wnt/β-catenin signaling pathway. Exp Mol Med. 2020;52(8):1310–1325. Epub 2020/ 08/12. PubMed PMID: 32778797
   PubMed Web of Science ®Google Scholar
• Kong Y, Nie ZK, Li F, et al. MiR-320a was highly expressed in postmenopausal osteoporosis and acts as a negative regulator in MC3T3E1 cells by reducing MAP9 and inhibiting PI3K/AKT signaling pathway. Exp Mol Pathol. 2019;110:104282. Epub 2019/ 07/14. PubMed PMID: 31301305.
   PubMed Web of Science ®Google Scholar
• De-Ugarte L, Balcells S, Nogues X, et al. Pro-osteoporotic miR-320a impairs osteoblast function and induces oxidative stress. PLoS One. 2018;13(11):e0208131. Epub 2018/ 11/30. PubMed PMID: 30485349; PubMed Central PMCID: PMCPMC6261634
   PubMed Web of Science ®Google Scholar
• Zhu XB, Lin WJ, Lv C, et al. MicroRNA-539 promotes osteoblast proliferation and differentiation and osteoclast apoptosis through the AXNA-dependent Wnt signaling pathway in osteoporotic rats. J Cell Biochem. 2018;119(10):8346–8358. PubMed PMID: 29893431.
   PubMed Web of Science ®Google Scholar
• Han J, Wang JZ, Yang X, et al. METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner. Mol Cancer. 2019;18(1):110. PubMed PMID: 31228940; PubMed Central PMCID: PMCPMC6588935.
   PubMed Web of Science ®Google Scholar
• Yu FY, Xie CQ, Sun JT, et al. Overexpressed miR-145 inhibits osteoclastogenesis in RANKL-induced bone marrow-derived macrophages and ovariectomized mice by regulation of Smad3. Life Sci. 2018;202:11–20. Epub 2018/ 03/27. PubMed PMID: 29577879
   PubMed Web of Science ®Google Scholar
• Wang S, Liu Z, Wang J, et al. miR‑21 promotes osteoclastogenesis through activation of PI3K/Akt signaling by targeting Pten in RAW264.7 cells. Mol Med Rep. 2020;21(3):1125–1132. Epub 2020/ 02/06. PubMed PMID: 32016444; PubMed Central PMCID: PMCPMC7003029
   PubMed Web of Science ®Google Scholar
• Black DM, Rosen CJ, Solomon CG.Postmenopausal osteoporosis.N Engl J Med.2016;374(21):2096–2097; Epub 2016/ 05/26. PubMed PMID: 27223157;
   PubMedGoogle Scholar
• Svedbom A, Hernlund E, Ivergård M, et al. Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos. 2013;8(1–2):137. Epub 2013/ 10/12. PubMed PMID: 24113838; PubMed Central PMCID: PMCPMC3880492
   PubMed Web of Science ®Google Scholar
• Harada S, Rodan GA.Control of osteoblast function and regulation of bone mass.Nature.2003;423(6937):349–355; Epub 2003/ 05/16. PubMed PMID: 12748654;
   PubMed Web of Science ®Google Scholar
• Ali AA, Weinstein RS, Stewart SA, et al. Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation. Endocrinology. 2005;146(3):1226–1235. Epub 2004/ 12/14. PubMed PMID: 15591153
   PubMed Web of Science ®Google Scholar
• Kretz M, Webster DE, Flockhart RJ, et al. Suppression of progenitor differentiation requires the long noncoding RNA ANCR. Genes Dev. 2012;26(4):338–343. Epub 2012/ 02/04. PubMed PMID: 22302877; PubMed Central PMCID: PMCPMC3289881
   PubMed Web of Science ®Google Scholar
• Liu L, Luo Q, Sun J, et al. Chromatin organization regulated by EZH2-mediated H3K27me3 is required for OPN-induced migration of bone marrow-derived mesenchymal stem cells. Int J Biochem Cell Biol. 2018;96:29–39. Epub 2018/ 01/18. PubMed PMID: 29337251.
   PubMed Web of Science ®Google Scholar
• Nie Z, Hu G, Wei G, et al. c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells. Cell. 2012;151(1):68–79. Epub 2012/ 10/02. PubMed PMID: 23021216; PubMed Central PMCID: PMCPMC3471363
   PubMed Web of Science ®Google Scholar
• Rahl PB, Lin CY, Seila AC, et al. c-Myc regulates transcriptional pause release. Cell. 2010;141(3):432–445. Epub 2010/ 05/04. PubMed PMID: 20434984; PubMed Central PMCID: PMCPMC2864022
   PubMed Web of Science ®Google Scholar
• Galibert L, Tometsko ME, Anderson DM, et al. The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanisms of receptor activator of NF-kappaB, a member of the TNFR superfamily. J Biol Chem. 1998;273(51):34120–34127. Epub 1998/ 12/16. PubMed PMID: 9852070
   PubMed Web of Science ®Google Scholar
• Yin Z, Zhu W, Wu Q, et al. Glycyrrhizic acid suppresses osteoclast differentiation and postmenopausal osteoporosis by modulating the NF-κB, ERK, and JNK signaling pathways. Eur J Pharmacol. 2019;859:172550. Epub 2019/ 07/20. PubMed PMID: 31323222
   PubMed Web of Science ®Google Scholar
• Khalifeh-Soltani A, Gupta D, Ha A, et al. The Mfge8-α8β1-PTEN pathway regulates airway smooth muscle contraction in allergic inflammation. Epub 2018/ 05/16. doi: 10.1096/fj.201800109R. PubMed PMID: 29763381 Faseb J. 2018;fj201800109R.
   PubMed Web of Science ®Google Scholar
• Yamada KM, Araki M.Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosis. J Cell Sci. 2001;1142:2375–2382. Epub 2001/ 09/18. PubMed PMID: 11559746
   PubMedGoogle Scholar
• Cantley LC, Neel BG.New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway.Proc Natl Acad Sci U S A.1999;96(8):4240–4245; Epub 1999/ 04/14. PubMed PMID: 10200246; PubMed Central PMCID: PMCPMC33561
   PubMed Web of Science ®Google Scholar
• Blüml S, Friedrich M, Lohmeyer T, et al. Loss of phosphatase and tensin homolog (PTEN) in myeloid cells controls inflammatory bone destruction by regulating the osteoclastogenic potential of myeloid cells. Ann Rheum Dis. 2015;74(1):227–233. Epub 2013/ 10/01. PubMed PMID: 24078675
   PubMed Web of Science ®Google Scholar
• Sugatani T, Alvarez U, Hruska KA.PTEN regulates RANKL- and osteopontin-stimulated signal transduction during osteoclast differentiation and cell motility.J Biol Chem.2003;278(7):5001–5008; Epub 2002/ 12/04. PubMed PMID: 12460992;
   PubMed Web of Science ®Google Scholar