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Research Paper

Identification of key immune genes for sepsis-induced ARDS based on bioinformatics analysis

, & ORCID Icon
Pages 697-708 | Received 28 Sep 2021, Accepted 25 Nov 2021, Published online: 30 Dec 2021

References

  • Cecconi M, Evans L, Levy M, et al. Sepsis and septic shock. Lancet. 2018;392(10141):75–87.
  • Reinhart K, Daniels R, Kissoon N, et al. Recognizing sepsis as a global health priority - a WHO resolution. N Engl J Med. 2017;377:414–417.
  • Xu F, Yuan J, Tian S, et al. MicroRNA-92a serves as a risk factor in sepsis-induced ARDS and regulates apoptosis and cell migration in lipopolysaccharide-induced HPMEC and A549 cell injury. Life Sci. 2020;256:117957.
  • Englert JA, Bobba C, Baron RM. Integrating molecular pathogenesis and clinical translation in sepsis-induced acute respiratory distress syndrome. JCI Insight. 2019;4(2). DOI:10.1172/jci.insight.124061
  • Lee LK, Medzikovic L, Eghbali M, et al. The role of MicroRNAs in acute respiratory distress syndrome and sepsis, from targets to therapies: a narrative review. Anesth Analg. 2020;131(5):1471–1484.
  • Sheu CC, Gong MN, Zhai R, et al. Clinical characteristics and outcomes of sepsis-related vs non-sepsis-related ARDS. Chest. 2010;138(3):559–567.
  • Zhou M, Fang H, Du M, et al. The modulation of regulatory T cells via HMGB1/PTEN/beta-catenin axis in LPS induced acute lung injury. Front Immunol. 2019;10:1612.
  • Wang M, Yan J, He X, et al. Candidate genes and pathogenesis investigation for sepsis-related acute respiratory distress syndrome based on gene expression profile. Biol Res. 2016;49(1):25.
  • Wang Z, Beach D, Su L, et al. A genome-wide expression analysis in blood identifies pre-elafin as a biomarker in ARDS. Am J Respir Cell Mol Biol. 2008;38(6):724–732.
  • Wang YM, Qi X, Gong FC, et al. Protective and predictive role of Mucin1 in sepsis-induced ALI/ARDS. Int Immunopharmacol. 2020;83:106438.
  • Meng L, Cao H, Wan C, et al. MiR-539-5p alleviates sepsis-induced acute lung injury by targeting ROCK1. Folia Histochem Cytobiol. 2019;57:168–178.
  • Xue M, Zhang S, Xie J, et al. Differential expression of genes associated with T lymphocytes function in septic patients with hypoxemia challenge. Ann Transl Med. 2019;7(24):810.
  • Arpaia N, Green JA, Moltedo B, et al. A distinct function of regulatory T cells in tissue protection. Cell. 2015;162(5):1078–1089.
  • Dial CF, Tune MK, Doerschuk CM, et al. Foxp3+ regulatory T cell expression of keratinocyte growth factor enhances lung epithelial proliferation. Am J Respir Cell Mol Biol. 2017;57(2):162–173.
  • Niu X, Zang L, Li W, et al. Anti-inflammatory effect of Yam Glycoprotein on lipopolysaccharide-induced acute lung injury via the NLRP3 and NF-kappaB/TLR4 signaling pathway. Int Immunopharmacol. 2020;81:106024.
  • Wei S, Wang K, Huang X, et al. Knockdown of the lncRNA MALAT1 alleviates lipopolysaccharide induced A549 cell injury by targeting the miR175p/FOXA1 axis. Mol Med Rep. 2019;20(2):2021–2029.
  • Xu C, Xu J, Lu L, et al. Identification of key genes and novel immune infiltration-associated biomarkers of sepsis. Innate Immun. 2020;26(8):666–682.
  • Hu Y, Cheng L, Zhong W, et al. Bioinformatics analysis of gene expression profiles for risk prediction in patients with septic shock. Med Sci Monit. 2019;25:9563–9571.
  • Silman NJ. Rapid diagnosis of sepsis using biomarker signatures. Crit Care. 2013;17(6):1020.
  • Matthay MA, Arabi YM, Siegel ER, et al. Phenotypes and personalized medicine in the acute respiratory distress syndrome. Intensive Care Med. 2020;46(12):2136–2152.
  • Hu Q, Hao C, Tang S. From sepsis to acute respiratory distress syndrome (ARDS): emerging preventive strategies based on molecular and genetic researches. Biosci Rep. 2020;40(5). DOI:10.1042/BSR20200830
  • Godini R, Fallahi H, Ebrahimie E. Network analysis of inflammatory responses to sepsis by neutrophils and peripheral blood mononuclear cells. PLoS One. 2018;13(8):e0201674.
  • Cheng L, Fan K, Huang Y, et al. Full characterization of localization diversity in the human protein interactome. J Proteome Res. 2017;16(8):3019–3029.
  • Breed ER, Hilliard CA, Yoseph B, et al. The small heat shock protein HSPB1 protects mice from sepsis. Sci Rep. 2018;8(1):12493.
  • Levy S, Todd SC, Maecker HT. CD81 (TAPA-1): a molecule involved in signal transduction and cell adhesion in the immune system. Annu Rev Immunol. 1998;16(1):89–109.
  • Anderson SJ, Lauritsen JP, Hartman MG, et al. Ablation of ribosomal protein L22 selectively impairs alphabeta T cell development by activation of a p53-dependent checkpoint. Immunity. 2007;26(6):759–772.