References
- Pollreisz A, Schmidt-Erfurth U. Diabetic cataract-pathogenesis, epidemiology and treatment. J Ophthalmol. 2010;2010:608751.
- Wong CW, Wong TY, Cheng C-Y, et al. Kidney and eye diseases: common risk factors, etiological mechanisms, and pathways. Kidney Int. 2014;85(6):1290–1302.
- Lanza M, Benincasa G, Costa D, et al. Clinical role of epigenetics and network analysis in eye diseases: a translational science review. J Ophthalmol. 2019;2019:2424956.
- Kikuchi K, Murata, K, Noda, S, et al. Diabetic cataract in spontaneously diabetic torii fatty rats. J Diabetes Res. 2020;2020:3058547.
- Zhang L, Wei W. Anti-inflammatory and immunoregulatory effects of paeoniflorin and total glucosides of paeony. Pharmacol Ther. 2020;207:107452.
- Wei T, Kulkarni NH, Zeng QQ, et al. Analysis of early changes in the articular cartilage transcriptisome in the rat meniscal tear model of osteoarthritis: pathway comparisons with the rat anterior cruciate transection model and with human osteoarthritic cartilage. Osteoarthritis Cartilage. 2010;18(7):992–1000.
- Bateman JF, Rowley, D, Belluoccio, B, et al. Transcriptomics of wild-type mice and mice lacking ADAMTS-5 activity identifies genes involved in osteoarthritis initiation and cartilage destruction. Arthritis Rheum. 2013;65(6):1547–1560.
- Sun X, Huang, x, Pan, S, et al. EGR1 promotes the cartilage degeneration and hypertrophy by activating the Kruppel-like factor 5 and beta-catenin signaling. Biochim Biophys Acta Mol Basis Dis. 2019;1865(9):2490–2503.
- Zhang Y, Gao, N, Li, H, et al. NDRG2 is expressed on enteric glia and altered in conditions of inflammation and oxygen glucose deprivation/reoxygenation. J Mol Histol. 2021;52(1):101–111.
- Takarada-Iemata M, Yoshikawa A, Ta HM, et al. N-myc downstream-regulated gene 2 protects blood-brain barrier integrity following cerebral ischemia. Glia. 2018;66(7):1432–1446.
- Wei M, Ma Y, Shen L, et al. NDRG2 regulates adherens junction integrity to restrict colitis and tumourigenesis. EBioMedicine. 2020;61:103068.
- Zhang Z, Chen X, Liu S. Role of Sirtuin-1 in neonatal hypoxic-ischemic encephalopathy and its underlying mechanism. Med Sci Monit. 2020;26:e924544.
- Yu W, Qin X, Zhang Y, et al. Curcumin suppresses doxorubicin-induced cardiomyocyte pyroptosis via a PI3K/Akt/mTOR-dependent manner. Cardiovasc Diagn Ther. 2020;10(4):752–769.
- Li W, Du Q, Li X, et al. Eriodictyol inhibits proliferation, metastasis and induces apoptosis of glioma cells via PI3K/Akt/NF-kappaB signaling pathway. Front Pharmacol. 2020;11:114.
- Xu W, Tao M, Hu Z, et al. Minocycline induces apoptosis of photoreceptor cells by regulating ER stress. Exp Eye Res. 2020;190:107887.
- Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001;25(4):402–408.
- Wang R, Li J, Zhang X, et al. Extracellular vesicles promote epithelial-to-mesenchymal transition of lens epithelial cells under oxidative stress. Exp Cell Res. 2021;398(1):112362.
- Babizhayev MA, Vishnyakova KS, Yegorov YE. Telomere-dependent senescent phenotype of lens epithelial cells as a biological marker of aging and cataractogenesis: the role of oxidative stress intensity and specific mechanism of phospholipid hydroperoxide toxicity in lens and aqueous. Fundam Clin Pharmacol. 2011;25(2):139–162.
- Stolarczyk A, Sarzyńska S, Gondek A, et al. Influence of diabetes on tissue healing in orthopaedic injuries. Clin Exp Pharmacol Physiol. 2018;45(7):619–627.
- Ahmed N, Thornalley PJ, Dawczynski J, et al. Methylglyoxal-derived hydroimidazolone advanced glycation end-products of human lens proteins. Invest Ophthalmol Vis Sci. 2003;44(12):5287–5292.
- Obrosova IG, Chung SS, Kador PF. Diabetic cataracts: mechanisms and management. Diabetes Metab Res Rev. 2010;26(3):172–180.
- Chen X, Xiao W, Chen W, et al. MicroRNA-26a and −26b inhibit lens fibrosis and cataract by negatively regulating Jagged-1/Notch signaling pathway. Cell Death Differ. 2017;24(8):1431–1442.
- Wu TT, Y, Y, Chen, HY, et al. AKR1B1-induced epithelial-mesenchymal transition mediated by RAGE-oxidative stress in diabetic cataract lens. Antioxidants (Basel). 2020;9(4):273.
- Shao YX, Gong Q, Qi X-M, et al. Paeoniflorin ameliorates macrophage infiltration and activation by inhibiting the tlr4 signaling pathway in diabetic nephropathy. Front Pharmacol. 2019;10:566.
- Zhu SH, Liu B-Q, Hao M-J, et al. Paeoniflorin suppressed high glucose-induced retinal microglia MMP-9 expression and inflammatory response via inhibition of TLR4/NF-kappaB pathway through upregulation of SOCS3 in diabetic retinopathy. Inflammation. 2017;40(5):1475–1486.
- Zhu X, Wang K, Zhou F, et al. Paeoniflorin attenuates atRAL-induced oxidative stress, mitochondrial dysfunction and endoplasmic reticulum stress in retinal pigment epithelial cells via triggering Ca(2+)/CaMKII-dependent activation of AMPK. Arch Pharm Res. 2018;41(10):1009–1018.
- Han X, Dong, XX, Shi, MY, et al. SUMOylation and deacetylation affect NF-kappaB p65 activity induced by high glucose in human lens epithelial cells. Int J Ophthalmol. 2019;12(9):1371–1379.
- Lou H, Yao J, Sun Y, et al. Role of blueberry anthocyanin extract in the expression of SIRT1 and NF-kappaB in rat lens epithelial cells in experimentally induced DM. Curr Eye Res. 2021;46(1):45–51.
- Zeng K, Feng, QG, Lin, BT, et al. Effects of microRNA-211 on proliferation and apoptosis of lens epithelial cells by targeting SIRT1 gene in diabetic cataract mice. Biosci Rep. 2017;37(4). DOI:10.1042/BSR20170695.
- Wang Y, Chen, J, Zhao, H, et al. Paeoniflorin attenuates oxidized low-density lipoprotein-induced apoptosis and adhesion molecule expression by autophagy enhancement in human umbilical vein endothelial cells. J Cell Biochem. 2019;120(6):9291–9299.
- Li X, Wang, F, Ren, M, et al. The effects of c-Src kinase on EMT signaling pathway in human lens epithelial cells associated with lens diseases. BMC Ophthalmol. 2019;19(1):219.
- Sun T, Jiao, L, Wang, Y, et al. SIRT1 induces epithelial-mesenchymal transition by promoting autophagic degradation of E-cadherin in melanoma cells. Cell Death Dis. 2018;9(2):136.
- Shirane A, Wada-Hiraike O, Tanikawa M, et al. Regulation of SIRT1 determines initial step of endometrial receptivity by controlling E-cadherin expression. Biochem Biophys Res Commun. 2012;424(3):604–610.