Knockdown of miR-92a suppresses the stemness of colorectal cancer cells via mediating SOCS3

References

• Brody H. Colorectal cancer. Nature. 2015;521(7551):S1.
   PubMed Web of Science ®Google Scholar
• Roncucci L, Lmariani F. Prevention of colorectal cancer: how many tools do we have in our basket? Eur J Intern Med. 2015;26(10):752–756.
   PubMed Web of Science ®Google Scholar
• Miller KD, Nogueira L, Mariotto AB, et al. Cancer treatment and survivorship statistics, 2019. CA Cancer J Clin. 2019;69(5):363–385.
   PubMed Web of Science ®Google Scholar
• Dawood S, Austin L, Lcristofanilli M. Cancer stem cells: implications for cancer therapy. Oncology (Williston Park). 2014;28(12):1101–1107.
   PubMed Web of Science ®Google Scholar
• Vlashi E, Pajonk F. Cancer stem cells, cancer cell plasticity and radiation therapy. Semin Cancer Biol. 2015;31:28–35.
   PubMed Web of Science ®Google Scholar
• Munro MJ, Wickremesekera SK, Peng L, et al. Cancer stem cells in colorectal cancer: a review. J Clin Pathol. 2018;71(2):110–116.
   PubMed Web of Science ®Google Scholar
• Tutar Y. miRNA and cancer; computational and experimental approaches. Curr Pharm Biotechnol. 2014;15(5):429.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Yun Z, Gong L, et al. Comparison of miRNA evolution and function in plants and animals. Microrna. 2018;7(1):4–10.
   PubMedGoogle Scholar
• Wojciechowska A, Braniewska A, Akozar-Kaminska K. MicroRNA in cardiovascular biology and disease. Adv Clin Exp Med. (2017);26(5):865–874.
   PubMed Web of Science ®Google Scholar
• Vishnoi A, Rani S. MiRNA biogenesis and regulation of diseases: an overview. Methods Mol Biol. 2017;1509:1–10.
   PubMedGoogle Scholar
• Zhu W, Long JL, Yin YT, et al. MicroRNA-34a suppresses the invasion and migration of colorectal cancer cells by enhancing EGR1 and inhibiting vimentin. Exp Ther Med. 2019;18(4):2459–2466.
   PubMed Web of Science ®Google Scholar
• An HJ, Park M, Kim J, et al. miR5191 functions as a tumor suppressor by targeting RPS6KB1 in colorectal cancer. Int J Oncol. 2019. DOI:10.3892/ijo.2019.4865
   Web of Science ®Google Scholar
• Wang LQ, Yu P, Li B, et al. miR-372 and miR-373 enhance the stemness of colorectal cancer cells by repressing differentiation signaling pathways. Mol Oncol. 2018;12(11):1949–1964.
   PubMed Web of Science ®Google Scholar
• Li X, Guo S, Min L, et al. S.miR-92a-3p promotes the proliferation, migration and invasion of esophageal squamous cell cancer by regulating PTEN. Int J Mol Med. (2019);44(3):973–981.
   PubMed Web of Science ®Google Scholar
• Sun B, Zhang J, Liu M, et al. Alkannin inhibits proliferation, migration and invasion of hepatocellular carcinoma cells via regulation of miR-92a. Biomed Pharmacother. 2019;114:108782.
   PubMed Web of Science ®Google Scholar
• Sun L, Jin X, Xie L, et al. Swainsonine represses glioma cell proliferation, migration and invasion by reduction of miR-92a expression. BMC Cancer. 2019;19(1):247.
   PubMedGoogle Scholar
• Peng Q, Shen Y, Lin K, et al. Identification of microRNA-92a and the related combination biomarkers as promising substrates in predicting risk, recurrence and poor survival of colorectal cancer. J Cancer. 2019;10(14):3154–3171.
   PubMed Web of Science ®Google Scholar
• Mahony R, Ahmed S, Diskin C, et al. SOCS3 revisited: a broad regulator of disease, now ready for therapeutic use? Cell Mol Life Sci. 2016;73(17):3323–3336.
   PubMed Web of Science ®Google Scholar
• Yin Y, Liu W, Dai Y. SOCS3 and its role in associated diseases. Hum Immunol. 2015;76(10):775–780.
   PubMed Web of Science ®Google Scholar
• Xu WP, D W. SOCS3: a potential therapeutic target for many human diseases. Yao Xue Xue Bao. 2011;46(7):747–752.
   PubMedGoogle Scholar
• Inagaki-Ohara K, Kondo T, Ito M, et al. SOCS, inflammation, and cancer. Jakstat. 2013;2(3):e24053.
   PubMedGoogle Scholar
• Chu Q, Shen D, He L, et al. Prognostic significance of SOCS3 and its biological function in colorectal cancer. Gene. 2017;627:114–122.
   PubMed Web of Science ®Google Scholar
• Ren D, Lin B, Zhang X, et al. Maintenance of cancer stemness by miR-196b-5p contributes to chemoresistance of colorectal cancer cells via activating STAT3 signaling pathway. Oncotarget. 2017;8(30):49807–49823.
   PubMed Web of Science ®Google Scholar
• Hu Y, Yan C, Mu L, et al. Fibroblast-derived exosomes contribute to chemoresistance through priming cancer stem cells in colorectal cancer. PLoS One. 2015;10(5):e0125625.
   PubMed Web of Science ®Google Scholar
• De Angelis ML, Zeuner A, Policicchio E, et al. Cancer stem cell-based models of colorectal cancer reveal molecular determinants of therapy resistance. Stem Cells Transl Med. 2016;5(4):511–523.
   PubMed Web of Science ®Google Scholar
• Li J, Condello S, Thomes-Pepin J, et al. Lipid desaturation is a metabolic marker and therapeutic target of ovarian cancer stem cells. Cell Stem Cell. 2017;20(3):303–314 e305.
   PubMed Web of Science ®Google Scholar
• VAN Schaijik B, Davis PF, Wickremesekera AC, et al. Subcellular localisation of the stem cell markers OCT4, SOX2, NANOG, KLF4 and c-MYC in cancer: a review. J Clin Pathol. 2018;71(1):88–91.
   PubMed Web of Science ®Google Scholar
• Amaya CN, Bryan BA. Enrichment of the embryonic stem cell reprogramming factors Oct4, Nanog, Myc, and Sox2 in benign and malignant vascular tumors. BMC Clin Pathol. 2015;15(1):18.
   PubMedGoogle Scholar
• Khan AQ, Ahmed EI, Elareer NR, et al. Role of miRNA-regulated cancer stem cells in the pathogenesis of human malignancies. Cells. 2019;8(8):840.
   PubMed Web of Science ®Google Scholar
• Samaeekia R, Adorno-Cruz V, Bockhorn J, et al. miR-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway. Clin Cancer Res. 2017;23(4):1091–1103.
   PubMed Web of Science ®Google Scholar
• Guo JC, Yang YJ, Zhang JQ, et al. microRNA-448 inhibits stemness maintenance and self-renewal of hepatocellular carcinoma stem cells through the MAGEA6-mediated AMPK signaling pathway. J Cell Physiol. 2019;234(12):23461–23474.
   PubMed Web of Science ®Google Scholar
• Chen X, Du P, She J, et al. Loss of ZG16 is regulated by miR-196a and contributes to stemness and progression of colorectal cancer. Oncotarget. 2016;7(52):86695–86703.
   PubMedGoogle Scholar
• Chen E, Li Q, Wang H, et al. MiR-92a promotes tumorigenesis of colorectal cancer, a transcriptomic and functional based study. Biomed Pharmacother. 2018;106:1370–1377.
   PubMed Web of Science ®Google Scholar
• Lv H, Zhang Z, Wang Y, et al. MicroRNA-92a promotes colorectal cancer cell growth and migration by inhibiting KLF4. Oncol Res. 2016;23(6):283–290.
   PubMed Web of Science ®Google Scholar
• Huynh J, Etemadi N, Hollande F, et al. The JAK/STAT3 axis: a comprehensive drug target for solid malignancies. Semin Cancer Biol. 2017;45:13–22.
   PubMed Web of Science ®Google Scholar
• Yu H, Lee H, Herrmann A, et al. Revisiting STAT3 signalling in cancer: new and unexpected biological functions. Nat Rev Cancer. 2014;14(11):736–746.
   PubMed Web of Science ®Google Scholar
• Hanada T, Kobayashi T, Chinen T, et al. IFNgamma-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice. J Exp Med. 2006;203(6):1391–1397.
   PubMed Web of Science ®Google Scholar
• Yoshida T, Ogata H, Kamio M, et al. SOCS1 is a suppressor of liver fibrosis and hepatitis-induced carcinogenesis. J Exp Med. 2004;199(12):1701–1707.
   PubMed Web of Science ®Google Scholar
• Inagaki-Ohara K, Mayuzumi H, Kato S, et al. Enhancement of leptin receptor signaling by SOCS3 deficiency induces development of gastric tumors in mice. Oncogene. 2014;33(1):74–84.
   PubMed Web of Science ®Google Scholar
• David M, Naudin C, Letourneur M, et al. Suppressor of cytokine signaling 1 modulates invasion and metastatic potential of colorectal cancer cells. Mol Oncol. 2014;8(5):942–955.
   PubMed Web of Science ®Google Scholar
• Letellier E, Schmitz M, Baig K, et al. Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer. Br J Cancer. 2014;111(4):726–735.
   PubMed Web of Science ®Google Scholar
• Sutherland KD, Vaillant F, Alexander WS, et al. c-myc as a mediator of accelerated apoptosis and involution in mammary glands lacking Socs3. EMBO J. 2006;25(24):5805–5815.
   PubMed Web of Science ®Google Scholar
• Zhang L, Li J, Li L, et al. IL-23 selectively promotes the metastasis of colorectal carcinoma cells with impaired Socs3 expression via the STAT5 pathway. Carcinogenesis. 2014;35(6):1330–1340.
   PubMed Web of Science ®Google Scholar
• He B, You L, Uematsu K, et al. SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer. Proc Natl Acad Sci U S A. 2003;100(24):14133–14138.
   PubMed Web of Science ®Google Scholar
• Li Y, Deuring J, Peppelenbosch MP, et al. IL-6-induced DNMT1 activity mediates SOCS3 promoter hypermethylation in ulcerative colitis-related colorectal cancer. Carcinogenesis. 2012;33(10):1889–1896.
   PubMed Web of Science ®Google Scholar