1,264
Views
6
CrossRef citations to date
0
Altmetric
Research Paper

Circular RNA circHIPK3 is downregulated in diabetic cardiomyopathy and overexpression of circHIPK3 suppresses PTEN to protect cardiomyocytes from high glucose-induced cell apoptosis

, , , , & ORCID Icon
Pages 6272-6279 | Received 31 Oct 2021, Accepted 11 Jan 2022, Published online: 24 Feb 2022

References

  • Zimmet P, Alberti KG, Magliano DJ, et al. Diabetes mellitus statistics on prevalence and mortality: facts and fallacies. Nat Rev Endocrinol. 2016 Oct;12(10):616–622.
  • Mirzaei H, Hamblin MR. Regulation of glycolysis by non-coding RNAs in cancer: switching on the Warburg effect. Mol Ther Oncolytics. 2020 Dec 16;19:218–239
  • Razavi ZS, Tajiknia V, Majidi S, et al. Gynecologic cancers and non-coding RNAs: epigenetic regulators with emerging roles. Crit Rev Oncol Hematol. 2021 Jan;157:103192.
  • Liese AD, Lawson A, Song HR, et al. Evaluating geographic variation in type 1 and type 2 diabetes mellitus incidence in youth in four US regions. Health Place. 2010 May;16(3):547–556.
  • Sinclair A, Saeedi P, Kaundal A, et al. Diabetes and global ageing among 65-99-year-old adults: findings from the international diabetes federation diabetes atlas, 9(th) edition. Diabetes Res Clin Pract. 2020 Apr;162:108078.
  • Cheung LTF, Chan RSM, GTC K, et al. Diet quality is inversely associated with obesity in Chinese adults with type 2 diabetes. Nutr J. 2018 Jul 3;17(1):63.
  • Forbes JM, Cooper ME. Mechanisms of diabetic complications. Physiol Rev. 2013 Jan;93(1):137–188.
  • Sharafati-Chaleshtori R, Nickdasti A, Mortezapour E, et al. Artemisia species as a new candidate for diabetes therapy: a comprehensive review. Curr Mol Med. 2021 Jan 1;21(10):832–849.
  • Boudina S, Abel ED, Boudina S, et al. Diabetic cardiomyopathy, causes and effects. Rev Endocr Metab Disord. 2010 Mar;11(1):31–39.
  • Jacob M, Chappell D, Rehm M. The ‘third space’–fact or fiction? Best Pract Res Clin Anaesthesiol. 2009 Jun;23(2):145–157.
  • Li YZ, Di Cristofano A, Woo M. Metabolic role of PTEN in insulin signaling and resistance. Cold Spring Harb Perspect Med. 2020 Aug 3;10(8):a036137.
  • Wu L, Chen Y, Chen Y, et al. Effect of HIF-1α/miR-10b-5p/PTEN on hypoxia-induced cardiomyocyte apoptosis. J Am Heart Assoc. 2019 Sep 17;8(18):e011948.
  • Lu S, Strand KA, Mutryn MF, et al. PTEN (Phosphatase and tensin homolog) protects against ang II (angiotensin II)-Induced pathological vascular fibrosis and remodeling-brief report. Arterioscler Thromb Vasc Biol. 2020 Feb;40(2):394–403.
  • Chen Y, Li C, Tan C, et al. Circular RNAs: a new frontier in the study of human diseases. J Med Genet. 2016 Jun;53(6):359–365.
  • Meng X, Li X, Zhang P, et al. Circular RNA: an emerging key player in RNA world. Brief Bioinf. 2017 Jul 1;18(4):547–557.
  • Abbaszadeh-Goudarzi K, Radbakhsh S, Pourhanifeh MH, et al. Circular RNA and diabetes: epigenetic regulator with diagnostic role. Curr Mol Med. 2020;20(7):516–526.
  • Borran S, Ahmadi G, Rezaei S, et al. Circular RNAs: new players in thyroid cancer. Pathol Res Pract. 2020 Oct;216(10):153217.
  • Nahand JS, Jamshidi S, Hamblin MR, et al. Circular RNAs: new epigenetic signatures in viral infections. Front Microbiol. 2020;11:1853.
  • Cao Y, Yuan G, Zhang Y, et al. High glucose-induced circHIPK3 downregulation mediates endothelial cell injury. Biochem Biophys Res Commun. 2018 Dec 9;507(1–4):362–368.
  • Cai SS, Tao XW, Long Y, et al. Effect of miR-26a on diabetic rats with myocardial injury by targeting PTEN. Eur Rev Med Pharmacol Sci. 2020 Oct;24(20):10307.
  • Yang F, Qin Y, Wang Y, et al. LncRNA KCNQ1OT1 mediates pyroptosis in diabetic cardiomyopathy. Cell Physiol Biochem. 2018;50(4):1230–1244.
  • Lai J, Xin J, Fu C, et al. CircHIPK3 promotes proliferation and metastasis and inhibits apoptosis of renal cancer cells by inhibiting MiR-485-3p. Cancer Cell Int. 2020;20(1):248.
  • Oudit GY, Sun H, Kerfant BG, et al. The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease. J Mol Cell Cardiol. 2004 Aug;37(2):449–471.