Fluoxetine attenuates apoptosis in early brain injury after subarachnoid hemorrhage through Notch1/ASK1/p38 MAPK signaling pathway

References

• Alkhachroum AM, Miller B, Chami T, et al. A troponin study on patients with ischemic stroke, intracerebral hemorrhage and subarachnoid hemorrhage: type II myocardial infarction is significantly associated with stroke severity, discharge disposition and mortality. J Clin Neurosci. 2019;64:83–88.
   PubMed Web of Science ®Google Scholar
• Wang CX, Xie G-B, Zhou C-H, et al. Baincalein alleviates early brain injury after experimental subarachnoid hemorrhage in rats: possible involvement of TLR4/NF-κB-mediated inflammatory pathway. Brain Res. 2015;1594:245–255.
   PubMed Web of Science ®Google Scholar
• Chen S, Xu P, Fang Y, et al. The updated role of the blood brain barrier in subarachnoid hemorrhage: from basic and clinical studies. Curr Neuropharmacol. 2020;18(12):1266–1278.
   PubMed Web of Science ®Google Scholar
• Zahid T, Eskander N, Emamy M, et al. Cardiac troponin elevation and outcome in subarachnoid hemorrhage. Cureus. 2020;12:e9792.
   PubMed Web of Science ®Google Scholar
• Yang Y, Jiang S, Dong Y, et al. Melatonin prevents cell death and mitochondrial dysfunction via a SIRT 1‐dependent mechanism during ischemic‐stroke in mice. J Pineal Res. 2015;58:61–70.
   PubMed Web of Science ®Google Scholar
• Mo J, Enkhjargal B, Travis ZD, et al. AVE 0991 attenuates oxidative stress and neuronal apoptosis via Mas/PKA/CREB/UCP-2 pathway after subarachnoid hemorrhage in rats. Redox Biol. 2019;20:75–86.
   PubMed Web of Science ®Google Scholar
• Kooijman E, Nijboer CH, van Velthoven CT, et al. The rodent endovascular puncture model of subarachnoid hemorrhage: mechanisms of brain damage and therapeutic strategies. J Neuroinflammation. 2014;11:2.
   PubMed Web of Science ®Google Scholar
• Ji C, Chen G. Signaling pathway in early brain injury after subarachnoid hemorrhage: news update. Acta Neurochir Suppl. 2016;121:123–126.
   PubMedGoogle Scholar
• Kanamaru H, Suzuki H. Potential therapeutic molecular targets for blood-brain barrier disruption after subarachnoid hemorrhage. Neural Regen Res. 2019;14:1138–1143.
   PubMed Web of Science ®Google Scholar
• Morris G, Walker AJ, Berk M, et al. Cell death pathways: a novel therapeutic approach for neuroscientists. Mol Neurobiol. 2018;55:5767–5786.
   PubMed Web of Science ®Google Scholar
• Liu W, Li R, Yin J, et al. Mesenchymal stem cells alleviate the early brain injury of subarachnoid hemorrhage partly by suppression of Notch1-dependent neuroinflammation: involvement of Botch. J Neuroinflammation. 2019;16(1):8.
   PubMedGoogle Scholar
• Yuan Y, Rangarajan P, Kan EM, et al. Scutellarin regulates the Notch pathway and affects the migration and morphological transformation of activated microglia in experimentally induced cerebral ischemia in rats and in activated BV-2 microglia. J Neuroinflammation. 2015;12(1):11.
   PubMedGoogle Scholar
• Hwang S, Kim J-K. Fluoxetine induces apoptotic and oxidative neuronal death associated with the influx of copper ions in cultured neuronal cells. Chonnam Med J. 2020;56:20–26.
   PubMedGoogle Scholar
• Wong DT, Bymaster FP, Engleman EA. Prozac (fluoxetine, Lilly 110140), the first selective serotonin uptake inhibitor and an antidepressant drug: twenty years since its first publication. Life Sci. 1995;57:411–441.
   PubMed Web of Science ®Google Scholar
• Lee JY, Kang SR, Yune TY. Fluoxetine prevents oligodendrocyte cell death by inhibiting microglia activation after spinal cord injury. J Neurotrauma. 2015;32:633–644.
   PubMed Web of Science ®Google Scholar
• Khodanovich M, Kisel A, Kudabaeva M, et al. Effects of fluoxetine on hippocampal neurogenesis and neuroprotection in the model of global cerebral ischemia in rats. Int J Mol Sci. 2018;19(1):162.
   PubMed Web of Science ®Google Scholar
• Alboni S, Poggini S, Garofalo S, et al. Fluoxetine treatment affects the inflammatory response and microglial function according to the quality of the living environment. Brain, behavior, and immunity. 2016;58:261–271.
   PubMed Web of Science ®Google Scholar
• Liu FY, Cai J, Wang C, et al. Fluoxetine attenuates neuroinflammation in early brain injury after subarachnoid hemorrhage: a possible role for the regulation of TLR4/MyD88/NF-κB signaling pathway. J Neuroinflammation. 2018;15:347.
   PubMed Web of Science ®Google Scholar
• Li J-R, Xu H-Z, Nie S, et al. Fluoxetine-enhanced autophagy ameliorates early brain injury via inhibition of NLRP3 inflammasome activation following subarachnoid hemorrhage in rats. J Neuroinflammation. 2017;14(1):1–14.
   PubMedGoogle Scholar
• Gräb J, Rybniker J. The expanding role of p38 mitogen-activated protein kinase in programmed host cell death. Microbiol Insights. 2019;12:1178636119864594.
   Google Scholar
• Koide M, Ferris HR, Nelson MT, et al. Impaired cerebral autoregulation after subarachnoid hemorrhage: a quantitative assessment using a mouse model. Front Physiol. 2021;12. DOI:10.3389/fphys.2021.688468.
   PubMed Web of Science ®Google Scholar
• Li J-R, Xu H-Z, Nie S, et al. Fluoxetine-enhanced autophagy ameliorates early brain injury via inhibition of NLRP3 inflammasome activation following subarachnoid hemorrhage in rats. J Neuroinflammation. 2017;14(1):186.
   PubMedGoogle Scholar
• Treen N, Heist T, Wang W, et al. Depletion of maternal cyclin B3 contributes to zygotic genome activation in the Ciona embryo. Curr Biol. 2018;28:1150–1156. e1154.
   PubMed Web of Science ®Google Scholar
• Delcambre GH, Liu J, Herrington JM, et al. Immunohistochemistry for the detection of neural and inflammatory cells in equine brain tissue. PeerJ. 2016;4:e1601.
   PubMed Web of Science ®Google Scholar
• Rong Y, Liu W, Wang J, et al. Neural stem cell-derived small extracellular vesicles attenuate apoptosis and neuroinflammation after traumatic spinal cord injury by activating autophagy. Cell Death Dis. 2019;10(5):340.
   PubMed Web of Science ®Google Scholar
• Lin KY, Cherng CG, Yang F-R, et al. Memantine abolishes the formation of cocaine-induced conditioned place preference possibly via its IL-6-modulating effect in medial prefrontal cortex. Behav Brain Res. 2011;220(1):126–131.
   PubMed Web of Science ®Google Scholar
• Takata K, Sheng H, Borel CO, et al. Simvastatin treatment duration and cognitive preservation in experimental subarachnoid hemorrhage. J Neurosurg Anesthesiol. 2009;21(4):326–333.
   PubMed Web of Science ®Google Scholar
• Silasi G, Colbourne F. Long-term assessment of motor and cognitive behaviours in the intraluminal perforation model of subarachnoid hemorrhage in rats. Behav Brain Res. 2009;198:380–387.
   PubMed Web of Science ®Google Scholar
• Huang C-Y, Wang L-C, Wang H-K, et al. Memantine alleviates brain injury and neurobehavioral deficits after experimental subarachnoid hemorrhage. Mol Neurobiol. 2015;51:1038–1052.
   PubMed Web of Science ®Google Scholar
• Quintard H, Borsotto M, Veyssiere J, et al. MLC901, a traditional Chinese medicine protects the brain against global ischemia. Neuropharmacology. 2011;61(4):622–631.
   PubMed Web of Science ®Google Scholar
• Chen J, Wang L, Wu C, et al. Melatonin-enhanced autophagy protects against neural apoptosis via a mitochondrial pathway in early brain injury following a subarachnoid hemorrhage. J Pineal Res. 2014;56(1):12–19.
   PubMed Web of Science ®Google Scholar
• Chen F, Lu J, Chen F, et al. Recombinant neuroglobin ameliorates early brain injury after subarachnoid hemorrhage via inhibiting the activation of mitochondria apoptotic pathway. Neurochem Int. 2018;112:219–226.
   PubMed Web of Science ®Google Scholar
• Pagie S, Gérard N, Charreau B. Notch signaling triggered via the ligand DLL4 impedes M2 macrophage differentiation and promotes their apoptosis. Cell Commun Signal. 2018;16(1):4.
   PubMed Web of Science ®Google Scholar
• Li Y, Tzatzalos E, Kwan KY, et al. Transcriptional regulation of Notch1 expression by nkx6.1 in neural stem/progenitor cells during ventral spinal cord development. Sci Rep. 2016;6:38665.
   PubMedGoogle Scholar
• Wang X, Mao X, Xie L, et al. Involvement of Notch1 signaling in neurogenesis in the subventricular zone of normal and ischemic rat brain in vivo. J Cereb Blood Flow and Metab. 2009;29:1644–1654.
   PubMed Web of Science ®Google Scholar
• Ntim M, Li Q-F, Zhang Y, et al. TRIM32 deficiency impairs synaptic plasticity by excitatory-inhibitory imbalance via notch pathway. Cerebral Cortex (New York, NY: 1991). 2020;30(8):4617–4632.
   PubMed Web of Science ®Google Scholar
• Ran Q-S, Yu Y-H, Fu X-H, et al. Activation of the Notch signaling pathway promotes neurovascular repair after traumatic brain injury. Neural Regen Res. 2015;10(8):1258–1264.
   PubMed Web of Science ®Google Scholar
• Sha L, Wu X, Yao Y, et al. Notch signaling activation promotes seizure activity in temporal lobe epilepsy. Mol Neurobiol. 2014;49(2):633–644.
   PubMed Web of Science ®Google Scholar
• Baik SH, Fane M, Park JH, et al. Pin1 promotes neuronal death in stroke by stabilizing Notch intracellular domain. Ann Neurol. 2015;77(3):504–516.
   PubMed Web of Science ®Google Scholar
• Balaganapathy P, Baik S-H, Mallilankaraman K, et al. Interplay between Notch and p53 promotes neuronal cell death in ischemic stroke. J Cereb Blood Flow and Metab. 2018;38(10):1781–1795.
   PubMed Web of Science ®Google Scholar
• Mathieu P, Adami PVM, Morelli L. Notch signaling in the pathologic adult brain. Biomol Concepts. 2013;4:465–476.
   PubMedGoogle Scholar
• Marracino L, Fortini F, Bouhamida E, et al. Adding a “Notch” to Cardiovascular Disease Therapeutics: a MicroRNA-Based Approach. Front Cell Dev Biol. 2021;9. DOI:10.3389/fcell.2021.695114.
   PubMed Web of Science ®Google Scholar
• Zhou J, Yang Z, Shen R, et al. Resveratrol Improves mitochondrial biogenesis function and activates PGC-1α pathway in a preclinical model of early brain injury following subarachnoid hemorrhage. Front Mol Biosci. 2021;8:620683.
   PubMed Web of Science ®Google Scholar
• Fan H, Ding R, Liu W, et al. Heat shock protein 22 modulates NRF1/TFAM-dependent mitochondrial biogenesis and DRP1-sparked mitochondrial apoptosis through AMPK-PGC1α signaling pathway to alleviate the early brain injury of subarachnoid hemorrhage in rats. Redox Biol. 2021;40:101856.
   PubMed Web of Science ®Google Scholar
• Macdonald RL, Schweizer TA. Spontaneous subarachnoid haemorrhage. Lancet (London, England). 2017;389:655–666.
   PubMed Web of Science ®Google Scholar
• Hu HM, Li B, Wang X-D, et al. Fluoxetine is neuroprotective in early brain injury via its anti-inflammatory and anti-apoptotic effects in a rat experimental subarachnoid hemorrhage model. Neurosci Bull. 2018;34(6):951–962.
   PubMed Web of Science ®Google Scholar
• Elena-Real CA, Díaz-Quintana A, González-Arzola K, et al. Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition. Cell Death Dis. 2018;9(3):365.
   PubMedGoogle Scholar
• Yue J, López JM. Understanding MAPK Signaling Pathways in Apoptosis. Int J Mol Sci. 2020;21:2346.
   PubMed Web of Science ®Google Scholar
• Cheon SY, Cho KJ, Kim SY, et al. Blockade of apoptosis signal-regulating kinase 1 attenuates matrix metalloproteinase 9 activity in brain endothelial cells and the subsequent apoptosis in neurons after ischemic injury. Front Cell Neurosci. 2016;10:213.
   PubMed Web of Science ®Google Scholar