References
- Brandes A, Tosoni A, Franceschi E, et al. Glioblastoma in adults. Crit Rev Oncol Hematol. 2008;67(2):139–152.
- Liu I, Hack O, Filbin M. The imitation game: how glioblastoma outmaneuvers immune attack. Cell. 2021;184(9):2278–2281.
- Lapointe S, Perry A, Butowski N. Primary brain tumours in adults. Lancet. 2018;392(10145):432–446.
- Baron R, Lakomkin N, Schupper A, et al. Postoperative outcomes following glioblastoma resection using a robot-assisted digital surgical exoscope: a case series. J Neurooncol. 2020;148(3):519–527.
- Tsien C. Stereotactic radiation therapy with concurrent immunotherapy for recurrent glioblastoma—hope or hype? Neuro Oncol. 2021;23(4):535–536.
- Chen S, Chao C, Chen S, et al. Fang C: flunarizine, a drug approved for treating migraine and vertigo, exhibits cytotoxicity in GBM cells. Eur J Pharmacol. 2021;892:173756.
- Di Sebastiano A, Deweyert A, Benoit S, et al. Preclinical outcomes of intratumoral modulation therapy for glioblastoma. Sci Rep. 2018;8(1):7301.
- Happold C, Gorlia T, Chinot O, et al. Does valproic acid or levetiracetam improve survival in glioblastoma? A pooled analysis of prospective clinical trials in newly diagnosed glioblastoma. J Clin Oncol. 2016;34(7):731–739.
- Johnson D, O’Neill BP. O’Neill B: glioblastoma survival in the United States before and during the temozolomide era. J Neurooncol. 2012;107(2):359–364.
- Zhao L, Han S, Hou J, et al. The local anesthetic ropivacaine suppresses progression of breast cancer by regulating miR-27b-3p/YAP axis. Aging (Albany NY). 2021;13(12):16341–16352.
- Li R, Xiao C, Liu H, et al. Effects of local anesthetics on breast cancer cell viability and migration. BMC Cancer. 2018;18(1):666.
- Qin A, Liu Q, Wang J. Ropivacaine inhibits proliferation, invasion, migration and promotes apoptosis of papillary thyroid cancer cells via regulating ITGA2 expression. Drug Dev Res. 2020;81(6):700–707.
- Piegeler T, Schläpfer M, Dull R, et al. Clinically relevant concentrations of lidocaine and ropivacaine inhibit TNFα-induced invasion of lung adenocarcinoma cells in vitro by blocking the activation of Akt and focal adhesion kinase. Br J Anaesth. 2015;115(5):784–791.
- Zhang N, Xing X, Gu F, et al. Ropivacaine inhibits the growth, migration and invasion of gastric cancer through attenuation of WEE1 and PI3K/AKT signaling via miR-520a-3p. Onco Targets Ther. 2020;13:5309–5321.
- Zhang Y, Peng X, Zheng Q. Ropivacaine inhibits the migration of esophageal cancer cells via sodium-channel-independent but prenylation-dependent inhibition of Rac1/JNK/paxillin/FAK. Biochem Biophys Res Commun. 2018;501(4):1074–1079.
- Fan X, Yang H, Zhao C, et al. Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation. Stem Cell Res Ther. 2021;12(1):107.
- Luo H, Xu C, Le W, et al. lncRNA CASC11 promotes cancer cell proliferation in bladder cancer through miRNA-150. J Cell Biochem. 2019;120(8):13487–13493.
- Xu B, Liu J, Xiang X, et al. Expression of miRNA-143 in pancreatic cancer and its clinical significance. Cancer Biother Radiopharm. 2018;33(9):373–379.
- Zhao X, Li D, Zhao S, et al. MiRNA-616 aggravates the progression of bladder cancer by regulating cell proliferation, migration and apoptosis through downregulating SOX7. Eur Rev Med Pharmacol Sci. 2019;23(21):9304–9312.
- He J, Li Y, Han Z, et al. The CircRNA-ACAP2/Hsa-miR-21-5p/ Tiam1 regulatory feedback circuit affects the proliferation, migration, and invasion of colon cancer SW480 cells. Cell Physiol Biochem. 2018;49(4):1539–1550.
- Ren W, Hou J, Yang C, et al. Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as macrophage M2 polarization via miR-21-5p delivery. J Exp Clin Cancer Res. 2019;38(1):62.
- Chen J, Zhou C, Li J, et al. miR-21-5p confers doxorubicin resistance in gastric cancer cells by targeting PTEN and TIMP3. Int J Mol Med. 2018;41(4):1855–1866.
- Cao J, Zhang Y, Mu J, et al. Exosomal miR-21-5p contributes to ovarian cancer progression by regulating CDK6. Hum Cell. 2021;34(4):1185–1196.
- Jiang J, Wang X, Lu J. PWRN1 suppressed cancer cell proliferation and migration in glioblastoma by inversely regulating hsa-miR-21-5p. Cancer Manag Res. 2020;12:5313–5322.
- Zottel A, Šamec N, Kump A, et al. Analysis of miR-9-5p, miR-124-3p, miR-21-5p, miR-138-5p, and miR-1-3p in glioblastoma cell lines and extracellular vesicles. Int J Mol Sci. 2020;21(22):8491.
- Khan H, Ni Z, Feng H, et al. Combination of curcumin with N-n-butyl haloperidol iodide inhibits hepatocellular carcinoma malignant proliferation by downregulating enhancer of zeste homolog 2 (EZH2) - lncRNA H19 to silence Wnt/β-catenin signaling. Phytomedicine. 2021;91:153706.
- Wang Y, Wang H, Li C, et al. CircTUBGCP3 contributes to the malignant progression of rectal cancer. Dig Dis Sci. 2021. DOI:10.1007/s10620-021-07135-7
- Chen J, Li N, Liu B, et al. Pracinostat (SB939), a histone deacetylase inhibitor, suppresses breast cancer metastasis and growth by inactivating the IL-6/STAT3 signalling pathways. Life Sci. 2020;248:117469.
- Knowles J, Golden B, Yan L, et al. Disruption of the AKT pathway inhibits metastasis in an orthotopic model of head and neck squamous cell carcinoma. Laryngoscope. 2011;121(11):2359–2365.
- Zhu Y, Yang T, Duan J, et al. MALAT1/miR-15b-5p/ mediates endothelial progenitor cells autophagy and affects coronary atherosclerotic heart disease via mTOR signaling pathway. Aging (Albany NY). 2019;11(4):1089–1109.
- Hu Y, Ma Y, Luo G, et al. Effect of MiR-375 regulates YAP1 on the invasion, apoptosis, and epithelial-mesenchymal transition of cervical cancer hela cells. Evid Based Complement Alternat Med. 2021;2021:3088723.
- Delello Di Filippo L, Hofstätter Azambuja J, Aparecida Paes Dutra J, et al. Improving temozolomide biopharmaceutical properties in glioblastoma multiforme (GBM) treatment using GBM-targeting nanocarriers. Eur J Pharm Biopharm. 2021;168:76–89.
- Lynch C. Local anesthetics as … Cancer therapy? Anesth Analg. 2018;127(3):601–602.
- Liu H, Dilger J, Lin J. Effects of local anesthetics on cancer cells. Pharmacol Ther. 2020;212:107558.
- Wang X, Li T. Ropivacaine inhibits the proliferation and migration of colorectal cancer cells through ITGB1. Bioengineered. 2021;12(1):44–53.
- Wang W, Zhu M, Xu Z, et al. Ropivacaine promotes apoptosis of hepatocellular carcinoma cells through damaging mitochondria and activating caspase-3 activity. Biol Res. 2019;52(1):36.
- Yin D, Liu L, Shi Z, et al. Ropivacaine inhibits cell proliferation, migration and invasion, whereas induces oxidative stress and cell apoptosis by circSCAF11/miR-145-5p axis in Glioma. Cancer Manag Res. 2020;12:11145–11155.
- Chen X, Liu W, Guo X, et al. Ropivacaine inhibits cervical cancer cell growth via suppression of the miR-96/MEG2/pSTAT3 axis. Oncol Rep. 2020;43(5):1659–1668.
- Y YZ, Geng J, Q LZ, et al. Dexmedetomidine enhances ropivacaine-induced sciatic nerve injury in diabetic rats. [J] Br J Anaesth. 2019;122:141–149.
- Whitlock Elizabeth L, Brenner Michael J, Fox Ida K, et al. Ropivacaine-induced peripheral nerve injection injury in the rodent model. [J] Anesth Analg. 2010;111:214–220.
- Alfardus H, de Los Angeles Estevez-cebrero M, Rowlinson J, et al. Intratumour heterogeneity in microRNAs expression regulates glioblastoma metabolism. Sci Rep. 2021;11(1):15908.
- Yu K, Yang H, Lv Q, et al. Construction of a competitive endogenous RNA network and analysis of potential regulatory axis targets in glioblastoma. Cancer Cell Int. 2021;21(1):102.
- Luo C, Lu Z, Chen Y, et al. MicroRNA-640 promotes cell proliferation and adhesion in glioblastoma by targeting Slit guidance ligand 1. Oncol Lett. 2021;21(2):161.
- Zhou J, Wang H, Hong F, et al. CircularRNA circPARP4 promotes glioblastoma progression through sponging miR-125a-5p and regulating FUT4. Am J Cancer Res. 2021;11(1):138–156.
- de Mooij T, Peterson T, Evans J, et al. Short non-coding RNA sequencing of glioblastoma extracellular vesicles. J Neurooncol. 2020;146(2):253–263.
- Papagiannakopoulos T, Shapiro A, Kosik K. MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res. 2008;68(19):8164–8172.
- Gulluoglu S, Tuysuz E, Sahin M, et al. Simultaneous miRNA and mRNA transcriptome profiling of glioblastoma samples reveals a novel set of OncomiR candidates and their target genes. Brain Res. 2018;1700:199–210.
- Dias J, Van Nguyen N, Georgiev P, et al. Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex. Genes Dev. 2014;28(9):929–942.
- Oladimeji P, Bakke J, Wright W, et al. KANSL2 and MBNL3 are regulators of pancreatic ductal adenocarcinoma invasion. Sci Rep. 2020;10(1):1485.
- Price K, Wigg K, Feng Y, et al. Genome-wide association study of word reading: overlap with risk genes for neurodevelopmental disorders. Genes, Brain and Behavior. 2020;19(6):e12648.
- Ferreyra Solari N, Belforte F, Canedo L, et al. The NSL chromatin-modifying complex subunit KANSL2 regulates cancer stem-like properties in glioblastoma that contribute to tumorigenesis. Cancer Res. 2016;76(18):5383–5394.