A comparison of capillary electrophoresis and next-generation sequencing in the detection of immunoglobulin heavy chain H and light chain κ gene rearrangements in the diagnosis of classic hodgkin’s lymphoma

References

• Ok CY, Medeiros LJ, Thakral B, et al. High-grade B-cell lymphomas with TdT expression: a diagnostic and classification dilemma. Mod Pathol. 2019;32(1):48–58.
   PubMed Web of Science ®Google Scholar
• Bray F , Ferlay J , Soerjomataram I. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin. 2018;68(6):394–424.
   PubMed Web of Science ®Google Scholar
• Swerdlow SH, Campo E, Pileri SA, et al. The 2016 revision of the world health organization classification of lymphoid neoplasms. Blood. 2016;127(20):2375–2390.
   PubMed Web of Science ®Google Scholar
• Zhu J, Ma J, For China lymphoma investigators of Csco U. Chinese Society of Clinical Oncology (CSCO) diagnosis and treatment guidelines for malignant lymphoma 2021 (English version). Chin J Cancer Res. 2021;33(3):289–301.
   PubMed Web of Science ®Google Scholar
• Bluth MJ, Bluth MH. Molecular Pathology Techniques: advances in 2018. Clin Lab Med. 2018;38(2):215–236.
   PubMed Web of Science ®Google Scholar
• Nikiforova MN, Hsi ED, Braziel RM, et al. Detection of clonal IGH gene rearrangements: summary of molecular oncology surveys of the College of American Pathologists. Arch Pathol Lab Med. 2007;131(2):185–189.
   PubMed Web of Science ®Google Scholar
• Illes A, Simon Z. New trends and novel possibilities in the diagnosis of lymphomas. Magy Onkol. 2015;59(1):73–78.
   PubMedGoogle Scholar
• van der Burg M, Tumkaya T, Boerma M, et al. Ordered recombination of immunoglobulin light chain genes occurs at the IGK locus but seems less strict at the IGL locus. Blood. 2001;97(4):1001–1008.
   PubMed Web of Science ®Google Scholar
• H. W W, J. P B, Pittaluga S, et al. Diagnosis of Hodgkin lymphoma in the modern era. Br J Haematol. 2019;184(1):45–59.
   PubMed Web of Science ®Google Scholar
• Jeon YK, Yoon SO, Paik JH, et al. Molecular testing of lymphoproliferative disorders: current status and perspectives. J Pathol Transl Med. 2017;51(3):224–241.
   PubMed Web of Science ®Google Scholar
• Nguyen JT, Kini AR, Li Y, et al. Analysis of immunoglobulin heavy chain rearrangement in a child with recurrent Burkitt lymphoma to determine clonality. J Pediatr Hematol Oncol. 2014;36(2):e125–e127.
   PubMed Web of Science ®Google Scholar
• van Krieken JH, Langerak AW, Macintyre EA, et al. Improved reliability of lymphoma diagnostics via PCR-based clonality testing: report of the BIOMED-2 concerted action BHM4-CT98-3936. Leukemia. 2007;21(2):201–206.
   PubMed Web of Science ®Google Scholar
• Ohshima K, Kikuchi M, Shibata T, et al. Clonal analysis of hodgkin’s disease shows absence of TCR/Ig gene rearrangement, compared with T-cell-rich B-cell lymphoma and incipient adult T-cell leukemia/lymphoma. Leuk Lymphoma. 1994;15(5–6):469–479.
   PubMed Web of Science ®Google Scholar
• Patel KP, Pan Q, Wang Y, et al. Comparison of BIOMED-2 versus laboratory-developed polymerase chain reaction assays for detecting T-cell receptor-gamma gene rearrangements. J Mol Diagn. 2010;12(2):226–237.
   PubMed Web of Science ®Google Scholar
• Kokovic I, Jezersek NB, Novakovic S. Diagnostic value of immunoglobulin kappa light chain gene rearrangement analysis in B-cell lymphomas. Int J Oncol. 2015;46(3):953–962.
   PubMed Web of Science ®Google Scholar
• Chi X, Li Y, Qiu X. V(D)J recombination, somatic hypermutation and class switch recombination of immunoglobulins: mechanism and regulation. Immunology. 2020;160(3):233–247.
   PubMed Web of Science ®Google Scholar
• Scott GB, de Wynter EA, Cook GP. Detecting variable (V), diversity (D) and joining (J) gene segment recombination using a two-colour fluorescence system. Mob DNA. 2010;1(1):9.
   PubMed Web of Science ®Google Scholar
• Schumacher JA, Duncavage EJ, Mosbruger TL, et al. A comparison of deep sequencing of TCRG rearrangements vs traditional capillary electrophoresis for assessment of clonality in T-Cell lymphoproliferative disorders. Am J Clin Pathol. 2014;141(3):348–359.
   PubMed Web of Science ®Google Scholar
• van Dongen JJ, Langerak AW, Brüggemann M, et al. Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia. 2003;17(12):2257–2317.
   PubMed Web of Science ®Google Scholar
• M.e A, Yu W, Syed M, et al. Establishment of immunoglobulin heavy (igh) chain clonality testing by next-generation sequencing for routine characterization of b-cell and plasma cell neoplasms. J Mol Diagn. 2019;21(2):330–342.
   PubMed Web of Science ®Google Scholar
• Li X. Pitfalls in the pathological diagnosis of lymphoma. Chin Clin Oncol. 2015;4(1):3.
   PubMedGoogle Scholar
• Chan JK, Kwong YL. Common misdiagnoses in lymphomas and avoidance strategies. Lancet Oncol. 2010;11(6):579–588.
   PubMed Web of Science ®Google Scholar
• Liu PL, Cheng ZX, Lu MP, et al. Misdiagnosis analysis: 120 patients with nasal extranodal NK/T cell lymphoma in head and neck. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020;34(1):73–78.
   PubMedGoogle Scholar
• Tokola S, Kuitunen H, Turpeenniemi-Hujanen T, et al. Interim and end-of-treatment PET-CT suffers from high false-positive rates in DLBCL: biopsy is needed prior to treatment decisions. Cancer Med. 2021;10(9):3035–3044.
   PubMed Web of Science ®Google Scholar
• Rea B, Haun P, Emerson R, et al. Role of high-throughput sequencing in the diagnosis of cutaneous T-cell lymphoma. J Clin Pathol. 2018;71(9):814–820.
   PubMed Web of Science ®Google Scholar
• Deonizio JM, Guitart J. The role of molecular analysis in cutaneous lymphomas. Semin Cutan Med Surg. 2012;31(4):234–240.
   PubMed Web of Science ®Google Scholar
• Hiemcke-Jiwa LS, Leguit RJ, Snijders TJ, et al. Molecular analysis in liquid biopsies for diagnostics of primary central nervous system lymphoma: review of literature and future opportunities. Crit Rev Oncol Hematol. 2018;127:56–65.
   PubMed Web of Science ®Google Scholar
• Maezawa M, Watanabe KI, Horiuchi N, et al. Molecular diagnosis of bovine B-cell lymphoma using polymerase chain reaction for immunoglobulin heavy chain gene. J Vet Med Sci. 2020;82(1):61–63.
   PubMed Web of Science ®Google Scholar
• Rothberg P.G., Langerak L.W., and Verhaaf B, et al. Bacon Penny Wright Anthony Bench Ming-Qing Du Hongxiang Liu P G R A. Clonal antigen receptor gene PCR products outsidethe expected size range. J Hematopathol. 2012;53:57–67.
   Google Scholar
• Sufficool KE, Lockwood CM, Abel HJ, et al. T-cell clonality assessment by next-generation sequencing improves detection sensitivity in mycosis fungoides. J Am Acad Dermatol. 2015;73(2):228–236.
   PubMed Web of Science ®Google Scholar
• Rivero ER, Neves AC, Silva-Valenzuela MG, et al. Simple salting-out method for DNA extraction from formalin-fixed, paraffin-embedded tissues. Pathol Res Pract. 2006;202(7):523–529.
   PubMed Web of Science ®Google Scholar
• Watanabe M, Hashida S, Yamamoto H, et al. Estimation of age-related DNA degradation from formalin-fixed and paraffin-embedded tissue according to the extraction methods. Exp Ther Med. 2017;14(3):2683–2688.
   PubMed Web of Science ®Google Scholar
• Guyard A, Boyez A, Pujals A, et al. DNA degrades during storage in formalin-fixed and paraffin-embedded tissue blocks. Virchows Arch. 2017;471(4):491–500.
   PubMed Web of Science ®Google Scholar
• Liu X, He H, Li Y, et al. The application of antigen receptor gene rearrangement of BIOMED-2 in the pathologic diagnosis of 348 cases with non-Hodgkin lymphoma in a single institution in Southwest of China. Pathol Res Pract. 2019;215(11):152615.
   PubMed Web of Science ®Google Scholar
• Han S, Masaki A, Sakamoto Y, et al. Improved clonality detection in Hodgkin lymphoma using a semi-nested modification of the BIOMED-2 PCR assay for IGH and IGK rearrangements: a paraffin-embedded tissue study. Pathol Int. 2018;68(5):287–293.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Xu N, B. J D, et al. Diagnostic significance of BIOMED-2 standardized gene rearran-gement system in patients with non-hodgkin’s lymphoma. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2017;25(1):115–119.
   PubMedGoogle Scholar
• Krause JC, Ekiert DC, Tumpey TM, et al. An insertion mutation that distorts antibody binding site architecture enhances function of a human antibody. mBio. 2011;2(1):e310–e345.
   Web of Science ®Google Scholar