The circular RNA circ_0030018/miR-136/migration and invasion enhancer 1 (MIEN1) axis promotes the progression of polycystic ovary syndrome

References

• Khan MJ, Ullah A, Basit S. Genetic basis of polycystic ovary syndrome (PCOS): current perspectives. Appl Clin Genet. 2019;12:249–260.
   PubMed Web of Science ®Google Scholar
• Patel S. Polycystic ovary syndrome (PCOS), an inflammatory, systemic, lifestyle endocrinopathy. J Steroid Biochem Mol Biol. 2018;182:27–36.
   PubMed Web of Science ®Google Scholar
• Dumesic DA, Lobo RA. Cancer risk and PCOS. Steroids. 2013;78(8):782–785.
   PubMed Web of Science ®Google Scholar
• Goodarzi MO, Dumesic DA, Chazenbalk G, et al. Polycystic ovary syndrome: etiology, pathogenesis and diagnosis. Nat Rev Endocrinol. 2011;7(4):219–231.
   PubMed Web of Science ®Google Scholar
• Escobar-Morreale HF. Polycystic ovary syndrome: definition, aetiology, diagnosis and treatment. Nat Rev Endocrinol. 2018;14(5):270–284.
   PubMed Web of Science ®Google Scholar
• Das M, Djahanbakhch O, Hacihanefioglu B, et al. Granulosa cell survival and proliferation are altered in polycystic ovary syndrome. J Clin Endocrinol Metab. 2008;93(3):881–887.
   PubMed Web of Science ®Google Scholar
• Mu L, Sun X, Tu M, et al. Non-coding RNAs in polycystic ovary syndrome: a systematic review and meta-analysis. Reprod Biol Endocrinol. 2021;19(1):10.
   PubMed Web of Science ®Google Scholar
• Kristensen LS, Andersen MS, Stagsted LVW, et al. The biogenesis, biology and characterization of circular RNAs. Nat Rev Genet. 2019;20(11):675–691.
   PubMed Web of Science ®Google Scholar
• Huang A, Zheng H, Wu Z, et al. Circular RNA-protein interactions: functions, mechanisms, and identification. Theranostics. 2020;10(8):3503–3517.
   PubMed Web of Science ®Google Scholar
• Han B, Chao J, Yao H. Circular RNA and its mechanisms in disease: from the bench to the clinic. Pharmacol Ther. 2018;187:31–44.
   PubMed Web of Science ®Google Scholar
• Hsiao KY, Sun HS, Tsai SJ. Circular RNA - new member of noncoding RNA with novel functions. Exp Biol Med (Maywood). 2017;242(11):1136–1141.
   PubMed Web of Science ®Google Scholar
• Ma Z, Zhao H, Zhang Y, et al. Novel circular RNA expression in the cumulus cells of patients with polycystic ovary syndrome. Arch Gynecol Obstet. 2019;299(6):1715–1725.
   PubMed Web of Science ®Google Scholar
• Zhang C, Liu J, Lai M, et al. Circular RNA expression profiling of granulosa cells in women of reproductive age with polycystic ovary syndrome. Arch Gynecol Obstet. 2019;300(2):431–440.
   PubMed Web of Science ®Google Scholar
• Wang C, Tang D, Wang H, et al. Circular RNA hsa_circ_0030018 acts as a sponge of miR-599 to aggravate esophageal carcinoma progression by regulating ENAH expression. J Cell Biochem. 2019. DOI:10.1002/jcb.29507
   Web of Science ®Google Scholar
• Shao Y, Yang Z, Miao W, et al. circ_0030018 promotes glioma proliferation and metastasis. Transl Neurosci. 2021;12(1):260–272.
   PubMed Web of Science ®Google Scholar
• Song D, Ye L, Xu Z, et al. CircRNA hsa_circ_0030018 regulates the development of glioma via regulating the miR-1297/RAB21 axis. Neoplasma. 2021;68(2):391–403.
   PubMed Web of Science ®Google Scholar
• Bushati N, Cohen SM. microRNA functions. Annu Rev Cell Dev Biol. 2007;23:175–205.
   PubMed Web of Science ®Google Scholar
• Chu Y, Hu X, Wang G, et al. Downregulation of miR-136 promotes the progression of osteosarcoma and is associated with the prognosis of patients with osteosarcoma. Oncol Lett. 2019;17(6):5210–5218.
   PubMed Web of Science ®Google Scholar
• Zhang C, Wang L, Chen J, et al. Differential expression of miR-136 in gestational diabetes mellitus mediates the high-glucose-induced trophoblast cell injury through targeting E2F1. Int J Genomics. 2020;2020:3645371.
   PubMed Web of Science ®Google Scholar
• Gao Z, Li Q, Zhang Y, et al. Ripasudil alleviated the inflammation of RPE cells by targeting the miR-136-5p/ROCK/NLRP3 pathway. BMC Ophthalmol. 2020;20(1):134.
   PubMed Web of Science ®Google Scholar
• Zhang D, Mou JY, Wang F, et al. CRNDE enhances neuropathic pain via modulating miR-136/IL6R axis in CCI rat models. J Cell Physiol. 2019;234(12):22234–22241.
   PubMed Web of Science ®Google Scholar
• Ji L, Zhang L, Li Y, et al. MiR-136 contributes to pre-eclampsia through its effects on apoptosis and angiogenesis of mesenchymal stem cells. Placenta. 2017;50:102–109.
   PubMed Web of Science ®Google Scholar
• Kushwaha PP, Gupta S, Singh AK, et al. Emerging role of migration and invasion enhancer 1 (MIEN1) in cancer progression and metastasis. Front Oncol. 2019;9:868.
   PubMed Web of Science ®Google Scholar
• Ren H, Qi Y, Yin X, et al. miR-136 targets MIEN1 and involves the metastasis of colon cancer by suppressing epithelial-to-mesenchymal transition. Onco Targets Ther. 2017;11:67–74.
   PubMed Web of Science ®Google Scholar
• Rotterdam ESHRE/ASRM-sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod. 2004;19(1):41–47.
   PubMed Web of Science ®Google Scholar
• Lou J, Hao Y, Lin K, et al. Circular RNA CDR1as disrupts the p53/MDM2 complex to inhibit Gliomagenesis. Mol Cancer. 2020;19(1):138.
   PubMed Web of Science ®Google Scholar
• Wang L, Long H, Zheng Q, et al. Circular RNA circRHOT1 promotes hepatocellular carcinoma progression by initiation of NR2F6 expression. Mol Cancer. 2019;18(1):119.
   PubMed Web of Science ®Google Scholar
• Li M, Zeng Z, Zhang A, et al. WGCNA analysis identifies polycystic ovary syndrome-associated circular RNAs that interact with RNA-binding proteins and sponge miRNAs. Int J Gen Med. 2021;14:8737–8751.
   PubMed Web of Science ®Google Scholar
• Huang P, Du S, Lin Y, et al. Identification of three potential circRNA biomarkers of polycystic ovary syndrome by bioinformatics analysis and validation. Int J Gen Med. 2021;14:5959–5968.
   PubMed Web of Science ®Google Scholar
• Liu J, Ding J, Qu B, et al. CircPSMC3 alleviates the symptoms of PCOS by sponging miR-296-3p and regulating PTEN expression. J Cell Mol Med. 2020;24(18):11001–11011.
   PubMed Web of Science ®Google Scholar
• Wu G, Xia J, Yang Z, et al. CircASPH promotes KGN cells proliferation through miR-375/MAP2K6 axis in polycystic ovary syndrome. J Cell Mol Med. 2020. DOI:10.1111/jcmm.16231
   Web of Science ®Google Scholar
• Zhao C, Zhou Y, Shen X, et al. Circular RNA expression profiling in the fetal side of placenta from maternal polycystic ovary syndrome and circ_0023942 inhibits the proliferation of human ovarian granulosa cell. Arch Gynecol Obstet. 2020;301(4):963–971.
   PubMed Web of Science ®Google Scholar
• Jia H, Wang H, Yao Y, et al. miR-136 inhibits malignant progression of hepatocellular carcinoma cells by targeting cyclooxygenase 2. Oncol Res. 2018;26(6):967–976.
   PubMed Web of Science ®Google Scholar
• Lu X, Gao H, Zhu B, et al. Circular RNA circ_RANBP9 exacerbates polycystic ovary syndrome via microRNA-136-5p/XIAP axis. Bioengineered. 2021;12(1):6748–6758.
   PubMed Web of Science ®Google Scholar
• Jia C, Wang S, Yin C, et al. Loss of hsa_circ_0118530 inhibits human granulosa-like tumor cell line KGN cell injury by sponging miR-136. Gene. 2020;744:144591.
   PubMed Web of Science ®Google Scholar
• Hsu CH, Shen TL, Chang CF, et al. Solution structure of the oncogenic MIEN1 protein reveals a thioredoxin-like fold with a redox-active motif. PLoS One. 2012;7(12):e52292.
   PubMed Web of Science ®Google Scholar