CDKN2B antisense RNA 1 expression alleviates idiopathic pulmonary fibrosis by functioning as a competing endogenouse RNA through the miR-199a-5p/Sestrin-2 axis

References

• Wolters PJ, Collard HR, Jones KD. Pathogenesis of idiopathic pulmonary fibrosis. Annu Rev Pathol. 2014;9(1):157–179.
   PubMed Web of Science ®Google Scholar
• Liu YM, Nepali K, Liou JP. Idiopathic pulmonary fibrosis: current status, recent progress, and emerging targets. J Med Chem. 2017;60(2):527–553.
   PubMed Web of Science ®Google Scholar
• King T, Bradford WZ, Castro-Bernardini S, et al. A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis. N Engl J Med. 2014;370(22):2083–2092.
   PubMed Web of Science ®Google Scholar
• Kropski J. Biomarkers and early treatment of idiopathic pulmonary fibrosis. Lancet Respir Med. 2019;7(9):725–727.
   PubMed Web of Science ®Google Scholar
• Mathy NW, Chen XM. Long non-coding RNAs (lncRNAs) and their transcriptional control of inflammatory responses. J Biol Chem. 2017;292(30):12375–12382.
   PubMed Web of Science ®Google Scholar
• Wang L, Zhang N, Zhang, Y, et al. Landscape of transcription and long non-coding RNAs reveals new insights into the inflammatory and fibrotic response following ventilator-induced lung injury. Respir Res. 2018;19(1):122.
   PubMed Web of Science ®Google Scholar
• Cai H, Zheng Y, Wen Z, et al. LncRNA AIRN influences the proliferation and apoptosis of hepatocellular carcinoma cells by regulating STAT1 ubiquitination. Arch Pharm Res. 2021;44(4):414–426.
   PubMed Web of Science ®Google Scholar
• Song C, Qi, Y, Zhang, J, et al. CDKN2B-AS1: an indispensable long non-coding RNA in multiple diseases. Curr Pharm Des. 2020;26(41):5335–5346.
   PubMed Web of Science ®Google Scholar
• Wang G, Xu G, Wang W. Long noncoding RNA CDKN2B-AS1 facilitates lung cancer development through regulating miR-378b/NR2C2. Onco Targets Ther. 2020;13:10641–10649.
   PubMed Web of Science ®Google Scholar
• Chen X, Yu X, Shen E. Overexpression of CDKN2B is involved in poor gastric cancer prognosis. J Cell Biochem. 2019;120(12):19825–19831.
   PubMed Web of Science ®Google Scholar
• Li Y, Zheng -L-L, Huang D-G, et al. LNCRNA CDKN2B-AS1 regulates mesangial cell proliferation and extracellular matrix accumulation via miR-424-5p/HMGA2 axis. Biomed Pharmacother. 2020;121:109622.
   PubMed Web of Science ®Google Scholar
• Ou M, Li X, Zhao S, et al. Long non-coding RNA CDKN2B-AS1 contributes to atherosclerotic plaque formation by forming RNA-DNA triplex in the CDKN2B promoter. EBioMedicine. 2020;55:102694.
   PubMed Web of Science ®Google Scholar
• Du Y, Hao X, Liu X. Low expression of long noncoding RNA CDKN2B-AS1 in patients with idiopathic pulmonary fibrosis predicts lung cancer by regulating the p53-signaling pathway. Oncol Lett. 2018. DOI:10.3892/ol.2018.7910
   Web of Science ®Google Scholar
• Lederer D, Martinez F, Longo DL. Idiopathic pulmonary fibrosis. N Engl J Med. 2018;378(19):1811–1823.
   PubMed Web of Science ®Google Scholar
• Heukels P, Moor CC, von der Thüsen JH, et al. Inflammation and immunity in IPF pathogenesis and treatment. Respir Med. 2019;147:79–91.
   PubMed Web of Science ®Google Scholar
• Yuan H, Xu J, Zhu Y, et al. Activation of calcium‑sensing receptor‑mediated autophagy in high glucose‑induced cardiac fibrosis in vitro. Mol Med Rep. 2020;22(3):2021–2031.
   PubMed Web of Science ®Google Scholar
• Racanelli AC, Choi AMK, Choi ME. Autophagy in chronic lung disease. Prog Mol Biol Transl Sci. 2020;172:135–156.
   PubMed Web of Science ®Google Scholar
• Li Y, Liu R, Wu J, et al. Self-eating: friend or foe? The emerging role of autophagy in fibrotic diseases. Theranostics. 2020;10(18):7993–8017.
   PubMed Web of Science ®Google Scholar
• Sosulski M, Gongora R, Danchuk S, et al. Deregulation of selective autophagy during aging and pulmonary fibrosis: the role of TGF β1. Aging Cell. 2015;14(5):774–783.
   PubMed Web of Science ®Google Scholar
• Hill C, Li, J, Liu, D, et al. Autophagy inhibition-mediated epithelial-mesenchymal transition augments local myofibroblast differentiation in pulmonary fibrosis. Cell Death Dis. 2019;10(8):591.
   PubMed Web of Science ®Google Scholar
• Lin X, Bai, D, Wei, Z, et al. Curcumin attenuates oxidative stress in RAW264.7 cells by increasing the activity of antioxidant enzymes and activating the Nrf2-Keap1 pathway. PLOS ONE. 2019;14 (5):e0216711.
   PubMed Web of Science ®Google Scholar
• Liu P, Feng Y, Dong D, et al. Enhanced renoprotective effect of IGF-1 modified human umbilical cord-derived mesenchymal stem cells on gentamicin-induced acute kidney injury. Sci Rep. 2016;6(1):20287.
   PubMed Web of Science ®Google Scholar
• Zhao L, Feng Y, Chen X, et al. Effects of IGF-1 on neural differentiation of human umbilical cord derived mesenchymal stem cells. Life Sci. 2016;151:93–101.
   PubMed Web of Science ®Google Scholar
• Ding LZ, Teng X, Zhang Z-B, et al. Mangiferin inhibits apoptosis and oxidative stress via BMP2/Smad-1 signaling in dexamethasone-induced MC3T3-E1 cells. Int J Mol Med. 2018. DOI:10.3892/ijmm.2018.3506.
   Web of Science ®Google Scholar
• Guo Y, Zhu X, Sun X. COTI-2 induces cell apoptosis in pediatric acute lymphoblastic leukemia via upregulation of miR-203. Bioengineered. 2020;11(1):201–208.
   PubMed Web of Science ®Google Scholar
• Li J, Li, P, Zhang, G, et al. CircRNA TADA2A relieves idiopathic pulmonary fibrosis by inhibiting proliferation and activation of fibroblasts. Cell Death Dis. 2020;11(7):553.
   PubMed Web of Science ®Google Scholar
• N K, Kamio K, Azuma A, et al. Exosome-derivedmicroRNA-22 ameliorates pulmonary fibrosis by regulating fibroblast-to-myofibroblast differentiation in vitro and in vivo. J Nippon Med Sch. 2020;87(3):118–128.
   PubMed Web of Science ®Google Scholar
• Ayana R, Singh S, Pati S. Decoding crucial LncRNAs implicated in neurogenesis and neurological disorders. Stem Cells Dev. 2017;26(8):541–553.
   PubMed Web of Science ®Google Scholar
• Yang M, Wang, M, Li, X, et al. The role of lncRNAs in signaling pathway implicated in CC. J Cell Biochem. 2019;120(3):2703–2712.
   PubMed Web of Science ®Google Scholar
• Savary G, Dewaeles, E, Diazzi, S, et al. The long noncoding RNA DNM3OS is a reservoir of fibromirs with major functions in lung fibroblast response to TGF-β and pulmonary fibrosis. Am J Respir Crit Care Med. 2019;200(2):184–198.
   PubMed Web of Science ®Google Scholar
• Wang X, Cheng Z, Dai L, et al. Knockdown of long noncoding RNA H19 represses the progress of pulmonary fibrosis through the transforming growth factor β/Smad3 pathway by regulating MicroRNA 140. Mol Cell Biol. 2019;39(12). DOI:10.1128/MCB.00143-19.
   Web of Science ®Google Scholar
• Zhen Q, Gao L-N, Wang R-F, et al. LncRNA DANCR promotes lung cancer by sequestering miR-216a. Cancer Control. 2018;25(1):1073274818769849.
   Web of Science ®Google Scholar
• Liu Y, Li Y, Xu Q, et al. Long non-coding RNA-ATB promotes EMT during silica-induced pulmonary fibrosis by competitively binding miR-200c. Biochim Biophys Acta Mol Basis Dis. 2018;1864(2):420–431.
   PubMed Web of Science ®Google Scholar
• Liu MW, Su, MX, Tang, DY, et al. Ligustrazin increases lung cell autophagy and ameliorates paraquat-induced pulmonary fibrosis by inhibiting PI3K/Akt/mTOR and hedgehog signalling via increasing miR-193a expression. BMC Pulm Med. 2019;19(1):35.
   PubMed Web of Science ®Google Scholar
• Lino Cardenas CL, Henaoui IS, Courcot E, et al. miR-199a-5p is upregulated during fibrogenic response to tissue injury and mediates TGFbeta-induced lung fibroblast activation by targeting caveolin-1. PLoS Genet. 2013;9(2):e1003291.
   PubMed Web of Science ®Google Scholar
• Lv X, Li K, Hu Z. Autophagy and pulmonary fibrosis. Adv Exp Med Biol. 2020;1207:569–579.
   PubMed Web of Science ®Google Scholar
• Liu H, Cheng Y, Yang J, et al. BBC3 in macrophages promoted pulmonary fibrosis development through inducing autophagy during silicosis. Cell Death Dis. 2017;8(3):e2657.
   PubMed Web of Science ®Google Scholar
• Ambrosio S, Saccà CD, Amente S, et al. Lysine-specific demethylase LSD1 regulates autophagy in neuroblastoma through SESN2-dependent pathway. Oncogene. 2017;36(48):6701–6711.
   PubMed Web of Science ®Google Scholar