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Research paper

SET domain containing 7 promotes oxygen-glucose deprivation/reoxygenation-induced PC12 cell inflammation and oxidative stress by regulating Keap1/Nrf2/ARE and NF-κB pathways

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Pages 7253-7261 | Received 13 Oct 2021, Accepted 18 Feb 2022, Published online: 08 Mar 2022

References

  • Kang HG, Cheong JS, Lim IH, et al. Antioxidative activity of statins and HDL-PON1 association in lacunar ischemic stroke with and without white matter hyperintensity. Signa Vitae. 2021;17:104–110.
  • Musuka TD, Wilton SB, Traboulsi M, et al. Diagnosis and management of acute ischemic stroke: speed is critical. CMAJ = Journal de l’Association Medicale Canadienne. 2015;187(12):887–893.
  • Pan J, Konstas -A-A, Bateman B, et al. Reperfusion injury following cerebral ischemia: pathophysiology, MR imaging, and potential therapies. Neuroradiology. 2007;49(2):93–102.
  • Zarbock A, Eroglu A, Erturk E, et al. Ischemia-reperfusion injury and anesthesia. Biomed Res Int. 2014;2014:980318.
  • D-s Q, J-h T, Zhang L-Q, et al. Neuroprotection of Cilostazol against ischemia/reperfusion-induced cognitive deficits through inhibiting JNK3/caspase-3 by enhancing Akt1. Brain Res. 2016;1653:67–74.
  • Li S, Jiang D, Ehlerding EB, et al. Intrathecal Administration of Nanoclusters for Protecting Neurons against Oxidative Stress in Cerebral Ischemia/Reperfusion Injury. ACS Nano. 2019;13(11):13382–13389.
  • Meng X, Xie W, Xu Q, et al. Neuroprotective Effects of Radix Scrophulariae on Cerebral Ischemia and Reperfusion Injury via MAPK Pathways. Molecules. 2018;23(9):2401.
  • Tamura R, Doi S, Nakashima A, et al. Inhibition of the H3K4 methyltransferase SET7/9 ameliorates peritoneal fibrosis. PloS one. 2018;13(5):e0196844–e0196844.
  • Soshnikova N, Liu H. Functions of SETD7 during development, homeostasis and cancer. Stem Cell Investig. 2019;6:6.
  • Lee J, Shao N-Y, Paik DT, et al. SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation. Cell Stem Cell. 2018;22(3):428–444.e425.
  • Bichmann M, Prat Oriol N, Ercan-Herbst E, et al. SETD7-mediated monomethylation is enriched on soluble Tau in Alzheimer’s disease. Mol Neurodegener. 2021;16(1):46.
  • Shen Y, Ding Z, Ma S, et al. SETD7 mediates spinal microgliosis and neuropathic pain in a rat model of peripheral nerve injury. Brain Behav Immun. 2019;82:382–395.
  • He S, Owen DR, Jelinsky SA, et al. Lysine Methyltransferase SETD7 (SET7/9) Regulates ROS Signaling through mitochondria and NFE2L2/ARE pathway. Sci Rep. 2015;5(1):14368.
  • Dang Y, Ma X, Li Y, et al. Inhibition of SETD7 protects cardiomyocytes against hypoxia/reoxygenation-induced injury through regulating Keap1/Nrf2 signaling. Biomed Pharmacother. 2018;106:842–849.
  • Yang Z, Wang L, Hu Y, et al. Butorphanol protects PC12 cells against OGD/R-induced inflammation and apoptosis. Mol Med Rep. 2020;22(3):1969–1975.
  • Shu K, Zhang Y. Protodioscin protects PC12 cells against oxygen and glucose deprivation-induced injury through miR-124/AKT/Nrf2 pathway. Cell Stress Chaperones. 2019;24(6):1091–1099.
  • Tang J, Zhuang S. Histone acetylation and DNA methylation in ischemia/reperfusion injury. Clin sci. 2019;133(4):597–609.
  • Zhao H, Han Z, Ji X, et al. Epigenetic Regulation of Oxidative Stress in Ischemic Stroke. Aging Dis. 2016;7(3):295–306.
  • Schweizer S, Harms C, Lerch H, et al. Inhibition of Histone Methyltransferases SUV39H1 and G9a Leads to Neuroprotection in an in vitro Model of Cerebral Ischemia. J Cereb Blood Flow Metab. 2015;35(10):1640–1647.
  • Zhang Z, Sun Y, Chen X. NLRC5 alleviated OGD/R-induced PC12-cell injury by inhibiting activation of the TLR4/MyD88/NF-κB pathway. J Int Med Res. 2020;48(8):300060520940455.
  • Zhuang L, Kong Y, Yang S, et al. Dynamic changes of inflammation and apoptosis in cerebral ischemia‑reperfusion injury in mice investigated by ferumoxytol‑enhanced magnetic resonance imaging. Mol Med Rep. 2021;23(4):1–13.
  • Chen W, Wang H, Feng J, et al. Overexpression of circRNA circUCK2 Attenuates Cell Apoptosis in Cerebral Ischemia-Reperfusion Injury via miR-125b-5p/GDF11 Signaling. Mol Ther Nucleic Acids. 2020;22:673–683.
  • Wu L, Xiong X, Wu X, et al. Targeting Oxidative Stress and Inflammation to Prevent Ischemia-Reperfusion Injury. Front Mol Neurosci. 2020;13:28.
  • Wu Y, Zou F, Lu Y, et al. SETD7 promotes TNF-α-induced proliferation and migration of airway smooth muscle cells in vitro through enhancing NF-κB/CD38 signaling. Int Immunopharmacol. 2019;72:459–466.
  • Zhao H, Chen Z, Xie L-J, et al. Suppression of TLR4/NF-κB Signaling Pathway Improves Cerebral Ischemia–Reperfusion Injury in Rats. Mol Neurobiol. 2018;55(5):4311–4319.
  • Wang X, Roper MG. Measurement of DCF fluorescence as a measure of reactive oxygen species in murine islets of Langerhans. Anal Methods. 2014;6(9):3019–3024.
  • Kobayashi M, Yamamoto M. Molecular Mechanisms Activating the Nrf2-Keap1 Pathway of Antioxidant Gene Regulation. Antioxid Redox Signal. 2005;7(3–4):385–394.
  • Satoh T, Okamoto S-I, and Cui J, et al. Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic phase II inducers. Proceedings of the National Academy of Sciences, USA. 2006; 103: 768–773.