1,749
Views
9
CrossRef citations to date
0
Altmetric
Research Paper

Long non-coding RNA ADAMTS9-AS1 attenuates ferroptosis by Targeting microRNA-587/solute carrier family 7 member 11 axis in epithelial ovarian cancer

, , , , &
Pages 8226-8239 | Received 22 Nov 2021, Accepted 28 Feb 2022, Published online: 21 Mar 2022

References

  • Bonifácio VDB. Ovarian cancer biomarkers: moving forward in early detection. Adv Exp Med Biol. 2020;1219:355–363.
  • Prat J. Ovarian carcinomas: five distinct diseases with different origins, genetic alterations, and clinicopathological features. Virchows Arch. 2012;460(3):237–249.
  • El-Arabey AA, Denizli M, Kanlikilicer P, et al. GATA3 as a master regulator for interactions of tumor-associated macrophages with high-grade serous ovarian carcinoma. Vol. 68. Cell Signal; 2020. p. 109539.
  • El-Arabey AA, Abdalla M, Abd-Allah AR. GATA3 and stemness of high-grade serous ovarian carcinoma: novel hope for the deadliest type of ovarian cancer. Hum Cell. 2020;33(3):904–906.
  • Rustin G, van der Burg M, Griffin C, et al. Early versus delayed treatment of relapsed ovarian cancer. Lancet. 2011;377(9763):380–381. DOI:10.1016/S0140-6736(11)60126-8.
  • Yang C, Xia BR, Zhang ZC, et al. Immunotherapy for ovarian cancer: adjuvant, combination, and neoadjuvant. Vol. 11. Front Immunol; 2020. p. 577869.
  • Schuijer M, Berns EM. TP53 and ovarian cancer. Hum Mutat. 2003;21(3):285–291.
  • Balch C, Fang F, Matei DE, et al. Minireview: epigenetic changes in ovarian cancer. Endocrinology. 2009;150(9):4003–4011. DOI:10.1210/en.2009-0404.
  • Nagano T, Fraser P. No-nonsense functions for long noncoding RNAs. Cell. 2011;145(2):178–181.
  • Wang H, Fu Z, Dai C, et al. LncRNAs expression profiling in normal ovary, benign ovarian cyst and malignant epithelial ovarian cancer. Sci Rep. 2016;6:38983.
  • Luo T, Jiang Y, Yang J. Long noncoding RNA LINC01554 as a novel biomarker for diagnosis and prognosis prediction of epithelial ovarian cancer. Vol. 2021. Dis Markers; 2021. p. 1244612.
  • Zhu W, Xiao X, Chen J. Silencing of the long noncoding RNA LINC01132 alleviates the oncogenicity of epithelial ovarian cancer by regulating the microRNA‑431‑5p/SOX9 axis. Int J Mol Med. 2021;48(2). DOI:10.3892/ijmm.2021.4984
  • Chen W, Tu Q, Yu L, et al. LncRNA ADAMTS9-AS1, as prognostic marker, promotes cell proliferation and EMT in colorectal cancer. Hum Cell. 2020;33(4):1133–1141. DOI:10.1007/s13577-020-00388-w.
  • Chen W, Tu Q, Yu L, et al. LncRNA ADAMTS9-AS1, as prognostic marker, promotes cell proliferation and EMT in colorectal cancer. J Transl Med. 2020;33(4):1133–1141.
  • Du L, Gao Y. PGM5-AS1 impairs miR-587-mediated GDF10 inhibition and abrogates progression of prostate cancer. J Transl Med. 2021;19(1):12.
  • Li XJ, Chen L-W, Gao P, et al. MiR-587 acts as an oncogene in non-small-cell lung carcinoma via reducing CYLD expression. Eur Rev Med Pharmacol Sci. 2020;24(24):12741–12747. DOI:10.26355/eurrev_202012_24173.
  • Chen M, Wang D, Liu J, et al. MicroRNA-587 functions as a tumor suppressor in hepatocellular carcinoma by targeting ribosomal protein SA. Biomed Res Int. 2020;2020:3280530.
  • Koppula P, Zhang Y, Shi J, et al. The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate. J Biol Chem. 2017;292(34):14240–14249. DOI:10.1074/jbc.M117.798405.
  • Shin SS, Jeong B-S, Wall BA, et al. Participation of xCT in melanoma cell proliferation in vitro and tumorigenesis in vivo. Oncogenesis. 2018;7(11):86. DOI:10.1038/s41389-018-0098-7.
  • Polewski MD, Reveron-Thornton RF, Cherryholmes GA, et al. SLC7A11 overexpression in glioblastoma is associated with increased cancer stem cell-like properties. Stem Cells Dev. 2017;26(17):1236–1246. DOI:10.1089/scd.2017.0123.
  • Ji X, Qian J, Rahman SMJ, et al. xCT (SLC7A11)-mediated metabolic reprogramming promotes non-small cell lung cancer progression. Oncogene. 2018;37(36):5007–5019. DOI:10.1038/s41388-018-0307-z.
  • Yin F, Yi S, Wei L, et al. Microarray-based identification of genes associated with prognosis and drug resistance in ovarian cancer. J Cell Biochem. 2019;120(4):6057–6070. DOI:10.1002/jcb.27892.
  • Yuan J, Liu Z, Song R. Antisense lncRNA As-SLC7A11 suppresses epithelial ovarian cancer progression mainly by targeting SLC7A11. Pharmazie. 2017;72(7):402–407.
  • Zhao X, Zhou M, Yang Y, et al. The ubiquitin hydrolase OTUB1 promotes glioma cell stemness via suppressing ferroptosis through stabilizing SLC7A11 protein. Bioengineered. 2021;12(2):12636–12645. DOI:10.1080/21655979.2021.2011633.
  • Dixon SJ, Lemberg K, Lamprecht M, et al. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell. 2012;149(5):1060–1072. DOI:10.1016/j.cell.2012.03.042.
  • Skouta R, Dixon SJ, Wang J, et al. Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models. J Am Chem Soc. 2014;136(12):4551–4556. DOI:10.1021/ja411006a.
  • Horwath MC, Bell-Horwath TR, Lescano V, et al. Antifungal activity of the lipophilic antioxidant ferrostatin-1. 2017;18(20):2069–2078. DOI: 10.1002/cbic.201700105
  • Chen M, Wang D, Liu J, et al. MicroRNA-587 functions as a tumor suppressor in hepatocellular carcinoma by targeting ribosomal protein SA. 2020;2020:3280530.
  • Krzystyniak J, Ceppi L, Dizon DS, et al. Epithelial ovarian cancer: the molecular genetics of epithelial ovarian cancer. Ann Oncol. 2016;27 Suppl 1(Suppl 1):i4–i10. DOI:10.1093/annonc/mdw083.
  • Xu S, Jia G, Zhang H, et al. LncRNA HOXB-AS3 promotes growth, invasion and migration of epithelial ovarian cancer by altering glycolysis. Vol. 264. Life Sci; 2021. p. 118636.
  • Li N, Li J, Mi Q, et al. Long non-coding RNA ADAMTS9-AS1 suppresses colorectal cancer by inhibiting the Wnt/β-catenin signalling pathway and is a potential diagnostic biomarker. J Cell Mol Med. 2020;24(19):11318–11329. DOI:10.1111/jcmm.15713.
  • Zhang Z, Li H, Hu Y, et al. Long non-coding RNA ADAMTS9-AS1 exacerbates cell proliferation, migration, and invasion via triggering of the PI3K/AKT/mTOR pathway in hepatocellular carcinoma cells. Am J Transl Res. 2020;12(9):5696–5707.
  • Li Z, et al. LncRNA ADAMTS9-AS1 knockdown restricts cell proliferation and EMT in non-small cell lung cancer. Histol Histopathol; 2021. p. 18347.
  • Qi X, Zhang D-H, Wu N, et al. ceRNA in cancer: possible functions and clinical implications. J Med Genet. 2015;52(10):710–718. DOI:10.1136/jmedgenet-2015-103334.
  • Karreth FA, Pandolfi PP. ceRNA cross-talk in cancer: when ce-bling rivalries go awry. Cancer Discov. 2013;3(10):1113–1121.
  • Fang S, Zhao Y, Hu X. LncRNA ADAMTS9-AS1 restrains the aggressive traits of breast carcinoma cells via sponging miR-513a-5p. Vol. 12. Cancer Manag Res; 2020. p. 10693–10703.
  • Zhou Z, Wu X, Zhou Y, et al. Long non-coding RNA ADAMTS9-AS1 inhibits the progression of prostate cancer by modulating the miR-142-5p/CCND1 axis. J Gene Med. 2021;23(5):e3331. DOI:10.1002/jgm.3331.
  • Lin W, Wang C, Liu G, et al. SLC7A11/xCT in cancer: biological functions and therapeutic implications. Am J Cancer Res. 2020;10(10):3106–3126.
  • Zhang L, Liu W, Liu F, et al. IMCA induces ferroptosis mediated by SLC7A11 through the AMPK/mTOR pathway in colorectal cancer. Oxid Med Cell Longev. 2020;2020:1675613.
  • Lin CC, Chi JT. Ferroptosis of epithelial ovarian cancer: genetic determinants and therapeutic potential. Oncotarget. 2020;11(39):3562–3570.
  • Hong T, Lei G, Chen X, et al. PARP inhibition promotes ferroptosis via repressing SLC7A11 and synergizes with ferroptosis inducers in BRCA-proficient ovarian cancer. Redox Biol. 2021;42:101928.