1,180
Views
3
CrossRef citations to date
0
Altmetric
Research Paper

Circular RNA Eps15-homology domain-containing protein 2 induce resistance of renal cell carcinoma to sunitinib via microRNA-4731-5p/ABCF2 axis

, &
Pages 9729-9740 | Received 06 Dec 2021, Accepted 25 Mar 2022, Published online: 12 Apr 2022

References

  • Lin L, Cai J. Circular RNA circ‐EGLN3 promotes renal cell carcinoma proliferation and aggressiveness via miR‐1299‐mediated IRF7 activation. J Cell Biochem. 2020;121(11):4377–4385.
  • Athanazio DA, Amorim LS, da Cunha IW, et al. Classification of renal cell tumors – current concepts and use of ancillary tests: recommendations of the Brazilian Society of Pathology. Surg Exp Pathol. 2021;4(1):4.
  • Rini BI, Hutson TE, Figlin RA, et al. Sunitinib in patients with metastatic renal cell carcinoma: clinical outcome according to international metastatic renal cell carcinoma database consortium risk group. Clin Genitourin Cancer. 2018;16(4):298–304.
  • Copur MS, Ledakis P, Norvell M. Nephrectomy for metastatic renal-cell cancer. N Engl J Med. 2002;346(14):1095–1096.
  • Zeng J, Feng Q, Wang Y, et al. Circular RNA circ_001842 plays an oncogenic role in renal cell carcinoma by disrupting microRNA-502-5p-mediated inhibition of SLC39A14. J Cell Mol Med. 2020;24(17):9712–9725.
  • Yao D, Xia S, Jin C, et al. Feedback activation of GATA1/miR-885-5p/PLIN3 pathway decreases sunitinib sensitivity in clear cell renal cell carcinoma. Cell Cycle. 2020;19(17):2195–2206.
  • Khosravan R, DuBois SG, Janeway K, et al. Extrapolation of pharmacokinetics and pharmacodynamics of sunitinib in children with gastrointestinal stromal tumors. Cancer Chemother Pharmacol. 2021;87(5):621–634.
  • Wang J, Cui X, Cheng C, et al. Effects of CYP3A inhibitors ketoconazole, voriconazole, and itraconazole on the pharmacokinetics of sunitinib and its main metabolite in rats. Chem Biol Interact. 2021;338:109426.
  • Nishikawa R, Osaki M, Sasaki R, et al. Splice variants of lysosome‑associated membrane proteins 2A and 2B are involved in sunitinib resistance in human renal cell carcinoma cells. Oncol Rep. 2020;44(5):1810–1820.
  • Kuroshima K, Yoshino H, Okamura S, et al. Potential new therapy of Rapalink-1, a new generation mammalian target of rapamycin inhibitor, against sunitinib-resistant renal cell carcinoma. Cancer Sci. 2020;111(5):1607–1618.
  • Kristensen LS, Andersen MS, Stagsted LVW, et al. The biogenesis, biology and characterization of circular RNAs. Nat Rev Genet. 2019;20(11):675–691.
  • Bozzoni I. Widespread occurrence of circular RNA in eukaryotes. Nat Rev Genet. 2021;22(9):550–551.
  • Vo JN, Cieslik M, Zhang Y, et al. The landscape of circular RNA in cancer. Cell. 2019;176(4):869–881.e813.
  • Hansen TB, Jensen TI, Clausen BH, et al. Natural RNA circles function as efficient microRNA sponges. Nature. 2013;495(7441):384–388.
  • Chen Q, Liu T, Bao Y, et al. CircRNA cRAPGEF5 inhibits the growth and metastasis of renal cell carcinoma via the miR-27a-3p/TXNIP pathway. Cancer Lett. 2020;469:68–77.
  • Zhou B, Zheng P, Li Z, et al. CircPCNXL2 sponges miR-153 to promote the proliferation and invasion of renal cancer cells through upregulating ZEB2. Cell Cycle. 2018;17(23):2644–2654.
  • Frey L, Klümper N, Schmidt D, et al. CircEHD2, CircNETO2 and CircEGLN3 as diagnostic and prognostic biomarkers for patients with renal cell carcinoma. Cancers (Basel). 2021;13(9):2177.
  • Shan L, Liu W, Zhan Y. Long non-coding RNA CCAT1 acts as an oncogene and promotes sunitinib resistance in renal cell carcinoma. Front Oncol. 2020;10:516552.
  • Barnes C, Kanhere A Identification of RNA–protein interactions through in vitro rna pull-down assays. In: Polycomb group proteins. Methods Mol Biol: Springer; 2016. p. 99–113.
  • Rice MA, Hsu EC, Aslan M, et al. Loss of Notch1 activity inhibits prostate cancer growth and metastasis and sensitizes prostate cancer cells to antiandrogen therapies. Mol Cancer Ther. 2019;18(7):1230–1242.
  • Xing Z, Zhang Z, Gao Y, et al. The lncRNA LINC01194/miR-486-5p axis facilitates malignancy in non-small cell lung cancer via regulating CDK4. Onco Targets Ther. 2020;13:3151–3163.
  • Kovacova J, Poprach A, Buchler T, et al. MicroRNAs as predictive biomarkers of response to tyrosine kinase inhibitor therapy in metastatic renal cell carcinoma. Clin Chem Lab Med. 2018;56(9):1426–1431.
  • Li L, Zhao S, Liu Z, et al. Sunitinib treatment promotes metastasis of drug-resistant renal cell carcinoma via TFE3 signaling pathway. Cell Death Dis. 2021;12(2):220.
  • Liu H, Hu G, Wang Z, et al. circPTCH1 promotes invasion and metastasis in renal cell carcinoma via regulating miR-485-5p/MMP14 axis. Theranostics. 2020;10(23):10791–10807.
  • Franz A, Ralla B, Weickmann S, et al. Circular RNAs in clear cell renal cell carcinoma: their microarray-based identification, analytical validation, and potential use in a Clinico-Genomic model to improve prognostic accuracy. Cancers (Basel). 2019;11(10):1473.
  • Liu C, Liu S, Wang L, et al. Effect of EH domain containing protein 2 on the biological behavior of clear cell renal cell carcinoma. Hum Exp Toxicol. 2019;38(8):927–937.
  • Yu R, Yao J, Ren Y. A novel circRNA, circNUP98, a potential biomarker, acted as an oncogene via the miR-567/ PRDX3 axis in renal cell carcinoma. J Cell Mol Med. 2020;24(17):10177–10188.
  • Kajdasz A, Majer W, Kluzek K, et al. Identification of RCC subtype-specific microRNAs-meta-analysis of high-throughput RCC tumor microrna expression data. Cancers (Basel). 2021;13(3):548.
  • Quan J, Pan X, Li Y, et al. MiR-23a-3p acts as an oncogene and potential prognostic biomarker by targeting PNRC2 in RCC. Biomed Pharmacother. 2019;110:656–666.
  • Liu HT, Fan WX. MiRNA-1246 suppresses the proliferation and migration of renal cell carcinoma through targeting CXCR4. Eur Rev Med Pharmacol Sci. 2020;24(11):5979–5987.
  • Ma X, Yuan Y, Lu J, et al. Long noncoding RNA ANCR promotes migration, invasion, EMT progress and stemness of nasopharyngeal carcinoma cells via the miR-4731-5p/NMT1 axis. Pathol Res Pract. 2021;224:153540.
  • Ying X, Zhu J, Zhang Y. Circular RNA circ-TSPAN4 promotes lung adenocarcinoma metastasis by upregulating ZEB1 via sponging miR-665. Mol Genet Genomic Med. 2019;7(12):e991.
  • Khlaiphuengsin A, TT NP, Tangkijvanich P, et al. Human miR-5193 triggers gene silencing in multiple genotypes of hepatitis B virus. Microrna. 2015;4(2):123–130.
  • Ye F, Zhang J, Zhang Q, et al. Preliminary study on the mechanism of long noncoding RNA SENCR regulating the proliferation and migration of vascular smooth muscle cells. J Cell Physiol. 2020;235(12):9635–9643.
  • Tsuda H, Ito K, Yaegashi N, et al. Relationship between ABCF2 expression and response to chemotherapy or prognosis in clear cell adenocarcinoma of the ovary. Int J Gynecol Cancer. 2010;20(5):794–797.
  • Bao L, Wu J, Dodson M, et al. ABCF2, an Nrf2 target gene, contributes to cisplatin resistance in ovarian cancer cells. Mol Carcinog. 2017;56(6):1543–1553.
  • Ogawa Y, Tsuda H, Hai E, et al. Clinical role of ABCF2 expression in breast cancer. Anticancer Res. 2006;26(3a):1809–1814.