Tumor targetable and pH-sensitive polymer nanoparticles for simultaneously improve the Type 2 Diabetes Mellitus and malignant breast cancer

References

• Storey S, Cohee A, Gathirua-Mwangi WG, et al. Impact of diabetes on the symptoms of breast cancer survivors. Oncol Nurs Forum. 2019;46(4):473–484.
   PubMed Web of Science ®Google Scholar
• Ashing KT, Lai L, Meyers E, et al. Exploring the association between diabetes and breast cancer morbidity: considerations for quality care improvements among Latinas. Int J Qual Health Care. 2020;32(2):120–125.
   PubMed Web of Science ®Google Scholar
• Griffiths RI, Valderas JM, McFadden EC, et al. Outcomes of preexisting diabetes mellitus in breast, colorectal, and prostate cancer. J Cancer Surviv. 2017;11(5):604–613.
   PubMed Web of Science ®Google Scholar
• Griffiths RI, McFadden EC, Stevens RJ, et al. Quality of diabetes care in breast, colorectal, and prostate cancer. J Cancer Surviv. 2018;12(6):803–812.
   PubMed Web of Science ®Google Scholar
• De Bruijn KM, Arends LR, Hansen BE, et al. Systematic review and meta-analysis of the association between diabetes mellitus and incidence and mortality in breast and colorectal cancer. Br J Surg. 2013;100(11):1421–1429.
   PubMed Web of Science ®Google Scholar
• Ling S, Brown K, Miksza JK, et al. Risk of cancer incidence and mortality associated with diabetes: a systematic review with trend analysis of 203 cohorts. Nutr Metab Cardiovasc Dis. 2021;31(1):14–22.
   PubMed Web of Science ®Google Scholar
• Wang CY, Shih SR, Huang KC. Increasing risk of diabetes mellitus in postmenopausal women with newly diagnosed primary breast cancer. J Diabetes Investig. 2020;11(2):490–498.
   PubMed Web of Science ®Google Scholar
• Hope C, Robertshaw A, Cheung KL, et al. Relationship between HbA1c and cancer in people with or without diabetes: a systematic review. Diabet Med. 2016;33(8):1013–1025.
   PubMed Web of Science ®Google Scholar
• Yang L, Yang J, Liang X, et al. Uncovering antiobesity-related hypertension targets and mechanisms of metformin, an antidiabetic medication. Bioengineered. 2021;12(1):4757–4767.
   PubMed Web of Science ®Google Scholar
• Meng F, Song L, Wang W. Metformin improves overall survival of colorectal cancer patients with diabetes: a meta-analysis. J Diabetes Res. 2017;2017:5063239.
   PubMed Web of Science ®Google Scholar
• Zhang W, Zhao L, Zhang J, et al. Metformin improves cognitive impairment in diabetic mice induced by a combination of streptozotocin and isoflurane anesthesia. Bioengineered. 2021;12(2):10982–10993.
   PubMed Web of Science ®Google Scholar
• Rojas J, Chávez-Castillo M, Bermúdez V. The role of metformin in metabolic disturbances during pregnancy: polycystic ovary syndrome and gestational Diabetes Mellitus. Int J Reprod Med. 2014;2014:797681.
   PubMedGoogle Scholar
• Chazin Ede L, Reis Rda R, Junior WT, et al. An overview on the development of new potentially active camptothecin analogs against cancer. Mini Rev Med Chem. 2014;14(12):953–962.
   PubMed Web of Science ®Google Scholar
• Pommier Y. Camptothecins and topoisomerase I: a foot in the door. Targeting the genome beyond topoisomerase I with camptothecins and novel anticancer drugs: importance of DNA replication, repair and cell cycle checkpoints. Curr Med Chem Anticancer Agents. 2004;4(5):429–434.
   PubMedGoogle Scholar
• Pommier Y. Topoisomerase I inhibitors: camptothecins and beyond. Nat Rev Cancer. 2006;6(10):789–802.
   PubMed Web of Science ®Google Scholar
• Neto WS, Jensen AT, Ferreira GR, et al. A survey on synthesis processes of structured materials for biomedical applications: iron-based magnetic nanoparticles, polymeric materials and polymerization processes. Curr Pharm Des. 2015;21(37):5336–5358.
   PubMed Web of Science ®Google Scholar
• Sarsaiya S, Shi J, Chen J. Bioengineering tools for the production of pharmaceuticals: current perspective and future outlook. Bioengineered. 2019;10(1):469–492.
   PubMed Web of Science ®Google Scholar
• Ahlawat J, Henriquez G, Narayan M. Enhancing the delivery of chemotherapeutics: role of biodegradable polymeric nanoparticles. Molecules. 2018;23(9):2157.
   PubMed Web of Science ®Google Scholar
• Yap JX, Leo CP, Mohd Yasin NH, et al. Recent advances of natural biopolymeric culture scaffold: synthesis and modification. Bioengineered. 2022;13(2):2226–2247.
   PubMed Web of Science ®Google Scholar
• Ruan S, Xie R, Qin L, et al. Aggregable nanoparticles-enabled chemotherapy and autophagy inhibition combined with Anti-PD-L1 antibody for improved glioma treatment. Nano Lett. 2019;19(11):8318–8332.
   PubMed Web of Science ®Google Scholar
• Feng X, Jiang D, Kang T, et al. Tumor-Homing and penetrating peptide-functionalized photosensitizer-conjugated PEG-PLA nanoparticles for chemo-photodynamic combination therapy of drug-resistant cancer. ACS Appl Mater Interfaces. 2016;8(28):17817–17832.
   PubMed Web of Science ®Google Scholar
• Luo YL, Yang XL, Xu F, et al. Thermosensitive PNIPAM-b-HTPB block copolymer micelles: molecular architectures and camptothecin drug release. Colloids Surf B Biointerfaces. 2014;114:150–157.
   PubMed Web of Science ®Google Scholar
• Cai K, He X, Song Z, et al. Dimeric drug polymeric nanoparticles with exceptionally high drug loading and quantitative loading efficiency. J Am Chem Soc. 2015;137(10):3458–3461.
   PubMed Web of Science ®Google Scholar
• Hoffman JA, Giraudo E, Singh M, et al. Progressive vascular changes in a transgenic mouse model of squamous cell carcinoma. Cancer Cell. 2003;4(5):383–391.
   PubMed Web of Science ®Google Scholar
• Hu Q, Gao X, Kang T, et al. CGKRK-modified nanoparticles for dual-targeting drug delivery to tumor cells and angiogenic blood vessels. Biomaterials. 2013;34(37):9496–9508.
   PubMed Web of Science ®Google Scholar
• Wu KK, Huan Y. Streptozotocin-induced diabetic models in mice and rats. Curr Protoc Pharmacol. 2008;40. Chapter 5:Unit 5.47. doi:10.1002/0471141755.ph0547s40.
   Google Scholar
• Ciccone V, Terzuoli E, Donnini S, et al. Stemness marker ALDH1A1 promotes tumor angiogenesis via retinoic acid/HIF-1alpha/VEGF signalling in MCF-7 breast cancer cells. J Exp Clin Cancer Res. 2018;37(1):311.
   PubMed Web of Science ®Google Scholar
• Pinkerton NM, Hadri K, Amouroux B, et al. Quench ionic flash nano precipitation as a simple and tunable approach to decouple growth and functionalization for the one-step synthesis of functional LnPO(4)-based nanoparticles in water. Chem Commun (Camb). 2018;54(68):9438–9441.
   PubMed Web of Science ®Google Scholar
• Lou J, Chu G, Zhou G, et al. Comparison between two kinds of cigarette smoke condensates (CSCs) of the cytogenotoxicity and protein expression in a human B-cell lymphoblastoid cell line using CCK-8 assay, comet assay and protein microarray. Mutat Res. 2010;697(1–2):55–59.
   PubMed Web of Science ®Google Scholar
• Wang T, Farvid MS, Kang JH, et al. Diabetes risk reduction diet and survival after breast cancer diagnosis. Cancer Res. 2021;81(15):4155–4162.
   PubMed Web of Science ®Google Scholar
• Miller B, Chalfant H, Thomas A, et al. Diabetes, Obesity, and Inflammation: impact on Clinical and Radiographic Features of Breast Cancer. Int J Mol Sci. 2021;22(5):2757.
   PubMed Web of Science ®Google Scholar
• Zhao XB, Ren GS. Diabetes mellitus and prognosis in women with breast cancer: a systematic review and meta-analysis. Medicine (Baltimore). 2016;95(49):e5602.
   PubMed Web of Science ®Google Scholar
• Meng W, He C, Hao Y, et al. Prospects and challenges of extracellular vesicle-based drug delivery system: considering cell source. Drug Deliv. 2020;27(1):585–598.
   PubMed Web of Science ®Google Scholar
• Khalid K, Tan X, Mohd Zaid HF, et al. Advanced in developmental organic and inorganic nanomaterial: a review. Bioengineered. 2020;11(1):328–355.
   PubMed Web of Science ®Google Scholar
• Rasool M, Malik A, Waquar S, et al. New challenges in the use of nanomedicine in cancer therapy. Bioengineered. 2021;13(1):759–773.
   Web of Science ®Google Scholar
• Hashemi M, Shamshiri A, Saeedi M, et al. Aptamer-conjugated PLGA nanoparticles for delivery and imaging of cancer therapeutic drugs. Arch Biochem Biophys. 2020;691:108485.
   PubMed Web of Science ®Google Scholar
• Sadat Tabatabaei Mirakabad F, Nejati-Koshki K, Akbarzadeh A, et al. PLGA-based nanoparticles as cancer drug delivery systems. Asian Pac J Cancer Prev. 2014;15(2):517–535.
   PubMedGoogle Scholar
• Gu P, Wusiman A, Wang S, et al. Polyethylenimine-coated PLGA nanoparticles-encapsulated Angelica sinensis polysaccharide as an adjuvant to enhance immune responses. Carbohydr Polym. 2019;223:115128.
   PubMed Web of Science ®Google Scholar
• Ravindran S, Suthar JK, Rokade R, et al. Pharmacokinetics, metabolism, distribution and permeability of nanomedicine. Curr Drug Metab. 2018;19(4):327–334.
   PubMed Web of Science ®Google Scholar
• Li SD, Huang L. Pharmacokinetics and biodistribution of nanoparticles. Mol Pharm. 2008;5(4):496–504.
   PubMed Web of Science ®Google Scholar
• Wang X, Xu J, Xu X, et al. pH-sensitive bromelain nanoparticles by ortho ester crosslinkage for enhanced doxorubicin penetration in solid tumor. Mater Sci Eng C Mater Biol Appl. 2020;113:111004.
   PubMed Web of Science ®Google Scholar
• Wang X, Wilhelm J, Li W, et al. Polycarbonate-based ultra-pH sensitive nanoparticles improve therapeutic window. Nat Commun. 2020;11(1):5828.
   PubMed Web of Science ®Google Scholar
• Feng Q, Wilhelm J, Gao J. Transistor-like Ultra-pH-Sensitive polymeric nanoparticles. Acc Chem Res. 2019;52(6):1485–1495.
   PubMed Web of Science ®Google Scholar
• Ernsting MJ, Murakami M, Roy A, et al. Factors controlling the pharmacokinetics, biodistribution and intratumoral penetration of nanoparticles. J Control Release. 2013;172(3):782–794.
   PubMed Web of Science ®Google Scholar
• Moghimi SM, Hunter AC, Andresen TL. Factors controlling nanoparticle pharmacokinetics: an integrated analysis and perspective. Annu Rev Pharmacol Toxicol. 2012;52:481–503.
   PubMed Web of Science ®Google Scholar