1,249
Views
2
CrossRef citations to date
0
Altmetric
Research Paper

Noncoding-RNA mediated high expression of zinc finger protein 268 suppresses clear cell renal cell carcinoma progression by promoting apoptosis and regulating immune cell infiltration

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, , , ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon show all
Pages 10467-10481 | Received 10 Jan 2022, Accepted 25 Mar 2022, Published online: 23 Apr 2022

References

  • Mao W, Wang K, Zhang H, et al. Sarcopenia as a poor prognostic indicator for renal cell carcinoma patients undergoing nephrectomy in China: a multicenter study. Clin Transl Med. 2021;11(1):e270.
  • Siegel RL, Miller KD, Fuchs HE, et al. Cancer Statistics, 2021. CA Cancer J Clin. 2021;71(1):7–33.
  • Capitanio U, et al. Epidemiology of renal cell carcinoma. Eur Urol. 2019;75(1):74–84. doi:10.1016/j.eururo.2018.08.036.
  • Hao J-F, Chen P, Li H-Y, et al. Effects of LncRNA HCP5/miR-214-3p/MAPK1 molecular network on renal cell carcinoma cells. Cancer Manag Res. 2020;12:13347–13356.
  • Lara PN, Evans CP. Cytoreductive nephrectomy in metastatic renal cell cancer: not all that It’s Cut Out to Be. JAMA Oncol. 2019;5(2):171–172.
  • Wang Y, Zhang Y, Wang P, et al. Circular RNAs in renal cell carcinoma: implications for tumorigenesis, diagnosis, and therapy. Mol Cancer. 2020;19(1):149.
  • Liu Y, Yin W, Wang J, et al. KRAB-zinc finger protein ZNF268a deficiency attenuates the virus-induced pro-inflammatory response by preventing IKK complex assembly. Cells. 2019;8(12):1604.
  • Shao H, Zhu C, Zhao Z, et al. KRAB-containing zinc finger gene ZNF268 encodes multiple alternatively spliced isoforms that contain transcription regulatory domains. Int J Mol Med. 2006;18(3):457–463.
  • Sun Y, Shao H, Li Z, et al. ZNF268, a novel kruppel-like zinc finger protein, is implicated in early human liver development. Int J Mol Med. 2004;14(6):971–975.
  • Zhao Z, Wang D, Zhu C, et al. Aberrant alternative splicing of human zinc finger gene ZNF268 in human hematological malignancy. Oncol Rep. 2008;20(5):1243–1248.
  • Kumar BV, Connors TJ, Farber DL. Human T Cell development, localization, and function throughout life. Immunity. 2018;48(2):202–213.
  • Zhou Y, Jiang D, Chu X, et al. Prognostic value of peripheral blood T lymphocyte subsets in clear cell renal cell carcinoma. Transl Androl Urol. 2021;10(1):326–335.
  • Dai S, Zeng H, Liu Z, et al. Intratumoral CXCL13 + CD8 + T cell infiltration determines poor clinical outcomes and immunoevasive contexture in patients with clear cell renal cell carcinoma. J Immunother Cancer. 2021;9(2):e001823.
  • Smyth GK, Michaud J, Scott HS. Use of within-array replicate spots for assessing differential expression in microarray experiments. Bioinformatics. 2005;21(9):2067–2075.
  • Wang K, Zhang, Y., Mao, W., et al. Engineering Ultrasmall Ferroptosis-Targeting and Reactive Oxygen/Nitrogen Species-Scavenging Nanozyme for Alleviating Acute Kidney Injury. Adv Functional Materials. 2022;2109221:32 . DOI:10.1002/adfm.202109221.
  • Li C, Hu J, Hu X, et al. LncRNA SNHG9 is a prognostic biomarker and correlated with immune infiltrates in prostate cancer. Transl Androl Urol. 2021;10(1):215–226.
  • Xie J, Chen L, Cao Y, et al. Single-cell sequencing analysis and weighted co-expression network analysis based on public databases identified that TNC is a novel biomarker for keloid. Front Immunol. 2021;12:783907.
  • Mao W, Wang K, Xu B, et al. ciRS-7 is a prognostic biomarker and potential gene therapy target for renal cell carcinoma. Mol Cancer. 2021;20(1):142.
  • Yang C-Y, Wang J, Zhang J-Q, et al. Human circular RNA hsa_circRNA_101705 (circTXNDC11) regulates renal cancer progression by regulating MAPK/ERK pathway. Bioengineered. 2021;12(1):4432–4441.
  • Yao Z, Shu L, Yi Y, et al. Hsa_circRNA_000543 predicts poor prognosis and promotes cervical cancer cell progression through regulating miR-567/ZNF268 axis. Cancer Manag Res. 2021;13:5211–5222.
  • Wang W, Guo M, Hu L, et al. The zinc finger protein ZNF268 is overexpressed in human cervical cancer and contributes to tumorigenesis via enhancing NF-κB signaling. J Biol Chem. 2012;287(51):42856–42866.
  • Hu L, Wang W, Cai J, et al. Aberrant expression of ZNF268 alters the growth and migration of ovarian cancer cells. Oncol Lett. 2013;6(1):49–54.
  • Sun Y, Gou D-M, Liu H, et al. The KRAB domain of zinc finger gene ZNF268: a potential transcriptional repressor. IUBMB Life. 2003;55(3):127–131.
  • Zeng Y, Wang W, Ma J, et al. Knockdown of ZNF268, which is transcriptionally downregulated by GATA-1, promotes proliferation of K562 cells. PloS one. 2012;7(1):e29518.
  • Sun Y, Gou DM, Liu H, et al. The KRAB domain of zinc finger gene ZNF268: a potential transcriptional repressor. IUBMB Life. 2003;55(3):127–131.
  • Lou W, Wang W, Chen J, et al. ncRNAs-mediated high expression of SEMA3F correlates with poor prognosis and tumor immune infiltration of hepatocellular carcinoma. Mol Ther Nucleic Acids. 2021;24:845–855.
  • Mao W, Wang K, Wu Z, et al. Current status of research on exosomes in general, and for the diagnosis and treatment of kidney cancer in particular. J Exp Clin Cancer Res. 2021;40(1):305.
  • Gao J, Yang D, Xu H, et al. ADAM metallopeptidase domain 12 overexpression correlates with prognosis and immune cell infiltration in clear cell renal cell carcinoma. Bioengineered. 2022;13(2):2412–2429.
  • Cui C, Wang J, Fagerberg E, et al. Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses. Cell. 2021;184(25):6101–6118.e6113.
  • Campe J, Ullrich E. T helper cell lineage-defining transcription factors: potent targets for specific GVHD therapy? Front Immunol. 2021;12:806529.
  • Sagnella SM, Yang L, Stubbs GE, et al. Cyto-immuno-therapy for cancer: a pathway elicited by tumor-targeted, cytotoxic drug-packaged bacterially derived nanocells. Cancer Cell. 2020;37(3):354–370.e357.
  • Klebanoff CA, Gattinoni , L, Torabi-Parizi, P, et al. Central memory self/tumor-reactive CD8 + T cells confer superior antitumor immunity compared with effector memory T cells. Proc Natl Acad Sci U S A. 2005;102(27):9571–9576. doi:10.1073/pnas.0503726102.
  • Maj T, Wang W, Crespo J, et al. Oxidative stress controls regulatory T cell apoptosis and suppressor activity and PD-L1-blockade resistance in tumor. Nat Immunol. 2017;18(12):1332–1341.
  • Gogali F, Paterakis G, Rassidakis GZ, et al. CD3 − CD16 − CD56 bright immunoregulatory NK cells are increased in the tumor microenvironment and inversely correlate with advanced stages in patients with papillary thyroid cancer. Thyroid. 2013;23(12):1561–1568.
  • Wang Y, Zhou , X, Han, P, et al. Inverse correlation of miR-27a-3p and CDH5 expression serves as a diagnostic biomarker of proliferation and metastasis of clear cell renal carcinoma. Pathol Res Pract. 2021;220:153393. doi:10.1016/j.prp.2021.153393.
  • Na XY, Hu XQ, Zhao Y, et al. LncRNA DNAJC3-AS1 functions as oncogene in renal cell carcinoma via regulation of the miR-27a-3p/PRDM14 axis. Eur Rev Med Pharmacol Sci. 2021;25(3):1291–1301.
  • Liao GR, Tseng YY, Tseng CY, et al. The orf virus (ORFV) protein OV20.0 interacts with the microprocessor complex subunit DGCR8 to regulate miRNA biogenesis and ORFV infection. FEBS Lett. 2021;595(23):2897–2908.
  • Tan C, Dai Y, Liu X, et al. STAT5A induced LINC01198 promotes proliferation of glioma cells through stabilizing DGCR8. Aging (Albany NY). 2020;12(7):5675–5692.