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Research Paper

Targeting CC chemokine ligand (CCL) 20 by miR-143-5p alleviate lead poisoning-induced renal fibrosis by regulating interstitial fibroblasts excessive proliferation and dysfunction

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Pages 11156-11168 | Received 24 Jan 2022, Accepted 26 Mar 2022, Published online: 29 Apr 2022

References

  • Hill NR, Fatoba ST, Oke JL, et al. Global prevalence of chronic kidney disease - a systematic review and meta-analysis. PLoS One. 2016;11:e0158765.
  • Lv JC, Zhang LX. Prevalence and disease burden of chronic kidney disease. Adv Exp Med Biol. 2019;1165:3–15.
  • Glassock RJ, Warnock DG, Delanaye P. The global burden of chronic kidney disease: estimates, variability and pitfalls. Nat Rev Nephrol. 2017;13:104–114.
  • Djudjaj S, Boor P. Cellular and molecular mechanisms of kidney fibrosis. Mol Aspects Med. 2019;65:16–36.
  • Humphreys BD. Mechanisms of renal fibrosis. Annu Rev Physiol. 2018;80:309–326.
  • Isaka Y, Takahara S, Imai E. Chronic deteriorating renal function and renal fibrosis. Contrib Nephrol. 2008;159:109–121.
  • Mascarenhas S, Mutnuri S, Ganguly A. Deleterious role of trace elements - silica and lead in the development of chronic kidney disease. Chemosphere. 2017;177:239–249.
  • Hanna-Attisha M, Lanphear B, Landrigan P. Lead poisoning in the 21st century: the silent epidemic continues. Am J Public Health .2018; . 108():1430.
  • Reja D, Makar M, Visaria A, et al. Blood lead level is associated with advanced liver fibrosis in patients with non-alcoholic fatty liver disease: a nationwide survey (NHANES 2011-2016. Ann Hepatol. 2020;19:404–410.
  • Obeng-Gyasi E. Sources of lead exposure in various countries. Rev Environ Health. 2019;34:25–34.
  • Ekong EB, Jaar BG, Weaver VM. Lead-related nephrotoxicity: a review of the epidemiologic evidence. Kidney Int. 2006;70:2074–2084.
  • Fan Y, Chen H, Huang Z, et al. Emerging role of miRNAs in renal fibrosis. RNA Biol. 2020;17:1–12.
  • Medrano S, Sequeira-Lopez MLS, Gomez RA. Deletion of the miR-143/145 cluster leads to hydronephrosis in mice. Am J Pathol. 2014;184(12):3226–3238.
  • Lin CF, Su CJ, Liu JH, et al. Potential Effects of CXCL9 and CCL20 on cardiac fibrosis in patients with myocardial infarction and isoproterenol-treated rats. J Clin Med. 2019;8:659.
  • Affo S, Morales-Ibanez O, Rodrigo-Torres D, et al. CCL20 mediates lipopolysaccharide induced liver injury and is a potential driver of inflammation and fibrosis in alcoholic hepatitis. Gut. 2014;63:1782–1792.
  • Tian S, Li C, Ran R, et al. Surfactant protein A deficiency exacerbates renal interstitial fibrosis following obstructive injury in mice. Biochim Biophys Acta Mol Basis Dis. 2017;1863:509–517.
  • Han L, Zhou R, Kuang X, et al. Study on lead-induced activation of rat renal interstitial fibroblasts and the related mechanisms. Toxicol Mech Methods. 2014;24:713–718.
  • Yi H, Peng R, Zhang LY, et al. LincRNA-Gm4419 knockdown ameliorates NF-kappaB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy. Cell Death Dis. 2017;8:e2583.
  • Li N, Wang LJ, Xu WL, et al. MicroRNA3795p suppresses renal fibrosis by regulating the LIN28/let7 axis in diabetic nephropathy. Int J Mol Med. 2019;44:1619–1628.
  • Yu J, Fujishiro H, Miyataka H, et al. Dichotomous effects of lead acetate on the expression of metallothionein in the liver and kidney of mice. Biol Pharm Bull. 2009;32:1037–1042.
  • Zhao B, Li H, Liu J, et al. MicroRNA-23b targets ras GTPase-activating protein SH3 domain-binding protein 2 to alleviate fibrosis and albuminuria in diabetic nephropathy. J Am Soc Nephrol. 2016;27:2597–2608.
  • Cheng X, Gao W, Dang Y, et al. Both ERK/MAPK and TGF-Beta/Smad signaling pathways play a role in the kidney fibrosis of diabetic mice accelerated by blood glucose fluctuation. J Diabetes Res. 2013;2013:463740.
  • Tang H, Zhang P, Zeng L, et al. Mesenchymal stem cells ameliorate renal fibrosis by galectin-3/Akt/GSK3beta/Snail signaling pathway in adenine-induced nephropathy rat, stem cell res. Ther. 2021;12:409.
  • Yuan Q, Tan RJ, Liu Y. Myofibroblast in kidney fibrosis: origin, activation, and regulation. Adv Exp Med Biol. 2019;1165:253–283.
  • Han L, Zhu B, Chen H, et al. Proteasome inhibitor MG132 inhibits the process of renal interstitial fibrosis. Exp Ther Med. 2019;17:2953–2962.
  • Isaka Y. Targeting TGF-beta signaling in kidney fibrosis. Int J Mol Sci. 2018;19. 10.3390/ijms19092532
  • Affo S, Rodrigo-Torres D, Blaya D, et al. Chemokine receptor Ccr6 deficiency alters hepatic inflammatory cell recruitment and promotes liver inflammation and fibrosis. PLoS One. 2015;10:e0145147.
  • Chu X, Jin Q, Chen H, et al. CCL20 is up-regulated in non-alcoholic fatty liver disease fibrosis and is produced by hepatic stellate cells in response to fatty acid loading. J Transl Med. 2018;16:108.
  • Jiang Z, Xia W, Dai G, et al. MicroRNA miR-4709-3p targets large tumor suppressor kinase 2 (LATS2) and induces obstructive renal fibrosis through hippo signaling. Bioengineered. 2021;12:12357–12371.
  • Bai S, Xiong X, Tang B, et al. Exosomal circ_DLGAP4 promotes diabetic kidney disease progression by sponging miR-143 and targeting ERBB3/NF-kappaB/MMP-2 axis. Cell Death Dis. 2020; 11:1008.
  • Ge X, Xi L, Wang Q, et al. Circular RNA Circ_0000064 promotes the proliferation and fibrosis of mesangial cells via miR-143 in diabetic nephropathy. Gene. 2020;758:144952.
  • Tu H, Chen D, Cai C, et al. Chen, microRNA-143-3p attenuated development of hepatic fibrosis in autoimmune hepatitis through regulation of TAK1 phosphorylation. J Cell Mol Med. 2020;24:1256–1267.
  • Loboda A, Sobczak M, Jozkowicz A, et al. TGF-beta1/Smads and miR-21 in renal fibrosis and inflammation. Mediators Inflamm. 2016;2016:8319283. 10.1155/2016/8319283
  • Kattla JJ, Carew RM, Heljic M, et al., Protein kinase B/Akt activity is involved in renal TGF-beta1-driven epithelial-mesenchymal transition in vitro and in vivo. Am J Physiol Renal Physiol . 2008;. 295:F215–225.
  • Chen YY, Chen XG, Zhang S. Druggability of lipid metabolism modulation against renal fibrosis. Acta Pharmacol Sin. 2022;43:505–519.
  • Zhang S, Xin H, Li Y, et al. Skimmin, a coumarin from hydrangea paniculata, slows down the progression of membranous glomerulonephritis by anti-inflammatory effects and inhibiting immune complex deposition. Evid Based Complement Alternat Med . . 2013;2013:819296.
  • Wang W, Sheng L, Chen Y, et al. Total coumarin derivates from hydrangea paniculata attenuate renal injuries in cationized-BSA induced membranous nephropathy by inhibiting complement activation and interleukin 10-mediated interstitial fibrosis. Phytomedicine. 2022;96:153886.