Family with sequence similarity 46 member a confers chemo-resistance to ovarian carcinoma via TGF-β/Smad2 signaling

References

• Chang SJ, Bristow RE. Surgical technique of en bloc pelvic resection for advanced ovarian cancer. J Gynecol Oncol. 2015;26(2):155.
   PubMed Web of Science ®Google Scholar
• Torre LA, Bray F, Siegel RL, et al. Global cancer statistics, 2012. CA Cancer J Clin. 2015;65(2):87–108.
   PubMed Web of Science ®Google Scholar
• Wright JD, Chen L, Tergas AI, et al. Trends in relative survival for ovarian cancer from 1975 to 2011. Obstet Gynecol. 2015;125(6):1345–1352.
   PubMed Web of Science ®Google Scholar
• Stewart C, Ralyea C, Lockwood S. Ovarian cancer: an integrated review. Semin Oncol Nurs. 2019;35(2):151–156.
   PubMed Web of Science ®Google Scholar
• Nash Z, Menon U. Ovarian cancer screening: current status and future directions. Best Pract Res Clin Obstetrics Gynaecol. 2020;65:32–45.
   PubMed Web of Science ®Google Scholar
• Menon U, Jacobs IJ. Ovarian cancer screening in the general population: current status. Int J Gynecol Cancer. 2001;11 Suppl 1(s1):3–6.
   PubMed Web of Science ®Google Scholar
• Zahreddine H, Borden KL. Mechanisms and insights into drug resistance in cancer. Front Pharmacol. 2013;4:28.
   PubMed Web of Science ®Google Scholar
• Housman G, Byler S, Heerboth S, et al. Drug resistance in cancer: an overview. Cancers (Basel). 2014;6(3):1769–1792.
   PubMed Web of Science ®Google Scholar
• Kellenberger LD, Bruin JE, Greenaway J, et al. The role of dysregulated glucose metabolism in epithelial ovarian cancer. J Oncol. 2010;2010:514310.
   PubMedGoogle Scholar
• Sankaranarayanan R, Ferlay J. Worldwide burden of gynaecological cancer: the size of the problem. Best Pract Res Clin Obstetrics Gynaecol. 2006;20(2):207–225.
   PubMed Web of Science ®Google Scholar
• Beaufort CM, Helmijr JC, Piskorz AM, et al. Ovarian cancer cell line panel (OCCP): clinical importance of in vitro morphological subtypes. PloS one. 2014;9(9):e103988.
   PubMed Web of Science ®Google Scholar
• Norouzi-Barough L, Sarookhani MR, Sharifi M, et al. Molecular mechanisms of drug resistance in ovarian cancer. J Cell Physiol. 2018;233(6):4546–4562.
   PubMed Web of Science ®Google Scholar
• Fang WB, Mafuvadze B, Yao M, et al. TGF-beta negatively regulates CXCL1 Chemokine expression in mammary fibroblasts through enhancement of Smad2/3 and suppression of HGF/c-Met signaling mechanisms. PloS one. 2015;10(8):e0135063.
   PubMed Web of Science ®Google Scholar
• Wang T, Wang D, Zhang L, et al. The TGFbeta-miR-499a-SHKBP1 pathway induces resistance to EGFR inhibitors in osteosarcoma cancer stem cell-like cells. J Exp Clin Cancer Res. 2019;38(1):226.
   PubMed Web of Science ®Google Scholar
• Futakuchi M, Lami K, Tachibana Y, et al. The effects of TGF-beta signaling on cancer cells and cancer stem cells in the bone microenvironment. Int J Mol Sci. 2019;20(20):5117.
   PubMed Web of Science ®Google Scholar
• Chen S, Huang J, Liu Z, et al. FAM83A is amplified and promotes cancer stem cell-like traits and chemoresistance in pancreatic cancer. Oncogenesis. 2017;6(3):e300.
   PubMed Web of Science ®Google Scholar
• Park J, Lee J, Kang W, et al. TGF-beta1 and hypoxia-dependent expression of MKP-1 leads tumor resistance to death receptor-mediated cell death. Cell Death Dis. 2013;4(2):e521.
   PubMed Web of Science ®Google Scholar
• Matsuzaka Y, Tounai K, Denda A, et al. Identification of novel candidate genes in the diffuse panbronchiolitis critical region of the class I human MHC. Immunogenetics. 2002;54(5):301–309.
   PubMed Web of Science ®Google Scholar
• Watanabe T, Yamamoto T, Tsukano K, et al. Fam46a regulates BMP-dependent pre-placodal ectoderm differentiation in Xenopus. Development. 2018;145(20). DOI:10.1242/dev.166710.
   Web of Science ®Google Scholar
• Etokebe GE, Zienolddiny S, Kupanovac Z, et al. Association of the FAM46A gene VNTRs and BAG6 rs3117582 SNP with non small cell lung cancer (NSCLC) in Croatian and Norwegian populations. PloS one. 2015;10(4):e0122651.
   PubMed Web of Science ®Google Scholar
• Lin HH, Lo YL, Wang WC, et al. Overexpression of FAM46A, a Non-canonical Poly(A) polymerase, promotes hemin-induced hemoglobinization in K562 cells. Front Cell Dev Biol. 2020;8:414.
   PubMed Web of Science ®Google Scholar
• Diener S, Bayer S, Sabrautzki S, et al. Exome sequencing identifies a nonsense mutation in Fam46a associated with bone abnormalities in a new mouse model for skeletal dysplasia. Mamm Genome. 2016;27(3–4):111–121.
   PubMed Web of Science ®Google Scholar
• Li J, Zhang N, Song LB, et al. Astrocyte elevated gene-1 is a novel prognostic marker for breast cancer progression and overall patient survival. Clin Cancer Res off J Am Assoc Cancer Res. 2008;14:3319–3326.
   PubMed Web of Science ®Google Scholar
• Li J, Gong LY, Song LB, et al. Oncoprotein Bmi-1 renders apoptotic resistance to glioma cells through activation of the IKK-nuclear factor-kappaB pathway. Am J Pathol. 2010;176(2):699–709.
   PubMed Web of Science ®Google Scholar
• He S, Niu G, Shang J, et al. The oncogenic Golgi phosphoprotein 3 like overexpression is associated with cisplatin resistance in ovarian carcinoma and activating the NF-kappaB signaling pathway. J Exp Clin Cancer Res. 2017;36(1):137.
   PubMed Web of Science ®Google Scholar
• Zhou X, Li Y, Wang W, et al. Regulation of Hippo/YAP signaling and esophageal squamous carcinoma progression by an E3 ubiquitin ligase PARK2. Theranostics. 2020;10(21):9443–9457.
   PubMed Web of Science ®Google Scholar
• Oshimori N, Oristian D, Fuchs E. TGF-beta promotes heterogeneity and drug resistance in squamous cell carcinoma. Cell. 2015;160(5):963–976.
   PubMed Web of Science ®Google Scholar
• Tripathi V, Shin JH, Stuelten CH, et al. TGF-beta-induced alternative splicing of TAK1 promotes EMT and drug resistance. Oncogene. 2019;38(17):3185–3200.
   PubMed Web of Science ®Google Scholar
• Xu X, Zhang L, He X, et al. TGF-beta plays a vital role in triple-negative breast cancer (TNBC) drug-resistance through regulating stemness, EMT and apoptosis. Biochem Biophys Res Commun. 2018;502(1):160–165.
   PubMed Web of Science ®Google Scholar
• Anido J, Saez-Borderias A, Gonzalez-Junca A, et al. TGF-beta receptor inhibitors target the CD44(high)/Id1(high) glioma-initiating cell population in human glioblastoma. Cancer Cell. 2010;18(6):655–668.
   PubMed Web of Science ®Google Scholar
• Cai J, Fang L, Huang Y, et al. Simultaneous overactivation of Wnt/beta-catenin and TGFbeta signalling by miR-128-3p confers chemoresistance-associated metastasis in NSCLC. Nat Commun. 2017;8(1):15870.
   PubMed Web of Science ®Google Scholar
• Ozes AR, Miller DF, Ozes ON, et al. NF-kappaB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer. Oncogene. 2016;35(41):5350–5361.
   PubMed Web of Science ®Google Scholar
• Chen MW, Yang ST, Chien MH, et al. The STAT3-miRNA-92-Wnt signaling pathway regulates spheroid formation and malignant progression in ovarian cancer. Cancer Res. 2017;77(8):1955–1967.
   PubMed Web of Science ®Google Scholar