Downregulated miR-18a and miR-92a synergistically suppress non-small cell lung cancer via targeting Sprouty 4

References

• Torre LA, Bray F, Siegel RL, et al. Global cancer statistics, 2012. CA Cancer J Clin. 2015;65(2):87–108.
   PubMed Web of Science ®Google Scholar
• Chen W, Zheng R, Baade PD, et al. Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66(2):115–132.
   PubMed Web of Science ®Google Scholar
• Stower H. Effective treatment of NSCLC. Nat Med. 2020;26(10):1512.
   Web of Science ®Google Scholar
• Sun S, Yang F, Zhu Y, et al. KDM4A promotes the growth of non-small cell lung cancer by mediating the expression of Myc via DLX5 through the Wnt/beta-catenin signaling pathway. Life Sci. 2020;262:118508.
   PubMed Web of Science ®Google Scholar
• Li H, Wu Q, Li T, et al. The miR-17-92 cluster as a potential biomarker for the early diagnosis of gastric cancer: evidence and literature review. Oncotarget. 2017;8(28):45060–45071.
   PubMedGoogle Scholar
• Wang J, Peng X, Li R, et al. Evaluation of serum miR-17-92 cluster as noninvasive biomarkers for bladder cancer diagnosis. Front Oncol. 2021;11:795837.
   PubMed Web of Science ®Google Scholar
• Yang CH, Jia X, Zhou J, et al. The miR-17-92 gene cluster is a blood-based marker for cancer detection in non-small-cell lung cancer. Am J Med Sci. 2020;360(3):248–260.
   PubMed Web of Science ®Google Scholar
• Bowen T, Jenkins RH, Fraser DJ. MicroRNAs, transforming growth factor beta-1, and tissue fibrosis. J Pathol. 2013;229(2):274–285.
   PubMed Web of Science ®Google Scholar
• Ma Z, Wang X. MicroRNA clusters -a tip of the iceberg in cancer therapy. J Invest Oncol. 2020;1(1):16–17.
   Google Scholar
• He L, Thomson JM, Hemann MT, et al. A microRNA polycistron as a potential human oncogene. Nature. 2005;435(7043):828–833.
   PubMed Web of Science ®Google Scholar
• Ota A, Tagawa H, Karnan S, et al. Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma. Cancer Res. 2004;64(9):3087–3095.
   PubMed Web of Science ®Google Scholar
• Masoumi-Moghaddam S, Amini A, Morris DL. The developing story of Sprouty and cancer. Cancer Metastasis Rev. 2014;33(2–3):695–720.
   PubMed Web of Science ®Google Scholar
• Sutterlüty H, Mayer C-E, Setinek U, et al. Down-regulation of Sprouty2 in non-small cell lung cancer contributes to tumor malignancy via extracellular signal-regulated kinase pathway-dependent and -independent mechanisms. Mol Cancer Res. 2007;5(5):509–520.
   PubMed Web of Science ®Google Scholar
• Tian L, Xiao H, Li M, et al. A novel Sprouty4-ERK1/2-Wnt/beta-catenin regulatory loop in marrow stromal progenitor cells controls osteogenic and adipogenic differentiation. Metabolism. 2020;105:154189.
   PubMed Web of Science ®Google Scholar
• Tennis MA, Van Scoyk MM, Freeman SV, et al. Sprouty-4 inhibits transformed cell growth, migration and invasion, and epithelial-mesenchymal transition, and is regulated by Wnt7A through PPARgamma in non-small cell lung cancer. Mol Cancer Res. 2010;8(6):833–843.
   PubMed Web of Science ®Google Scholar
• Liang C, Zhang X, Wang H-M, et al. MicroRNA-18a-5p functions as an oncogene by directly targeting IRF2 in lung cancer. Cell Death Dis. 2017;8(5):e2764–e2764.
   PubMed Web of Science ®Google Scholar
• Li YL, Liu X-M, Zhang C-Y, et al. MicroRNA-34a/EGFR axis plays pivotal roles in lung tumorigenesis. Oncogenesis. 2017;6(8):e372.
   PubMed Web of Science ®Google Scholar
• Zhang C, Han X, Yang L, et al. Circular RNA circPPM1F modulates M1 macrophage activation and pancreatic islet inflammation in type 1 diabetes mellitus. Theranostics. 2020;10(24):10908–10924.
   PubMed Web of Science ®Google Scholar
• Wang P, Liu X, Shao Y, et al. MicroRNA-107-5p suppresses non-small cell lung cancer by directly targeting oncogene epidermal growth factor receptor. Oncotarget. 2017;8(34):57012–57023.
   PubMedGoogle Scholar
• Zhou J, Wang H, Sun Q, et al. miR-224-5p-enriched exosomes promote tumorigenesis by directly targeting androgen receptor in non-small cell lung cancer. Mol Ther Nucleic Acids. 2021;23:1217–1228.
   PubMedGoogle Scholar
• Shao Y, Liu X, Meng J, et al. MicroRNA-1251-5p promotes carcinogenesis and autophagy via targeting the tumor suppressor TBCC in ovarian cancer cells. Mol Ther. 2019;27(9):1653–1664.
   PubMed Web of Science ®Google Scholar
• Lu C, Shan Z, Hong J, et al. MicroRNA-92a promotes epithelial-mesenchymal transition through activation of PTEN/PI3K/AKT signaling pathway in non-small cell lung cancer metastasis. Int J Oncol. 2017;51(1):235–244.
   PubMed Web of Science ®Google Scholar
• Zhang C, Wang H, Liu X, et al. Oncogenic microRNA-411 promotes lung carcinogenesis by directly targeting suppressor genes SPRY4 and TXNIP. Oncogene. 2019;38(11):1892–1904.
   PubMed Web of Science ®Google Scholar
• Hine J, Paterson H, Abrol E, et al. SGLT inhibition and euglycaemic diabetic ketoacidosis. Lancet Diabetes Endocrinol. 2015;3(7):503–504.
   PubMed Web of Science ®Google Scholar
• Ishikawa N, Oguri T, Isobe T, et al. SGLT gene expression in primary lung cancers and their metastatic lesions. Jpn J Cancer Res. 2001;92(8):874–879.
   PubMedGoogle Scholar
• Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell. 2010;140(6):883–899.
   PubMed Web of Science ®Google Scholar
• Xiao C, Srinivasan L, Calado DP, et al. Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes. Nat Immunol. 2008;9(4):405–414.
   PubMed Web of Science ®Google Scholar
• Wu Y, Heinrichs J, Bastian D, et al. MicroRNA-17-92 controls T-cell responses in graft-versus-host disease and leukemia relapse in mice. Blood. 2015;126(11):1314–1323.
   PubMed Web of Science ®Google Scholar
• Li L, Zhang J, Peng H, et al. Knockdown of miR-92a suppresses the stemness of colorectal cancer cells via mediating SOCS3. Bioengineered. 2022;13(3):5613–5624.
   PubMed Web of Science ®Google Scholar
• Jin L, Zhang Y, Jiang Y, et al. Circular RNA Rbms1 inhibited the development of myocardial ischemia reperfusion injury by regulating miR-92a/BCL2L11 signaling pathway. Bioengineered. 2022;13(2):3082–3092.
   PubMed Web of Science ®Google Scholar
• Zhang X, Li Y, Qi P, et al. Biology of miR-17-92 cluster and its progress in lung cancer. Int J Med Sci. 2018;15(13):1443–1448.
   PubMed Web of Science ®Google Scholar
• Fang LL, Wang X-H, Sun B-F, et al. Expression, regulation and mechanism of action of the miR-17-92 cluster in tumor cells (Review). Int J Mol Med. 2017;40(6):1624–1630.
   PubMed Web of Science ®Google Scholar
• Wang J, Thompson B, Ren C, et al. Sprouty4, a suppressor of tumor cell motility, is down regulated by DNA methylation in human prostate cancer. Prostate. 2006;66(6):613–624.
   PubMed Web of Science ®Google Scholar