298
Views
2
CrossRef citations to date
0
Altmetric
Letter

Effects of MSC-NTF cells on T and B regulatory cell function in ALS

, , , &
Pages 638-639 | Received 07 Jun 2020, Accepted 20 Jul 2020, Published online: 18 Aug 2020

References

  • Giovannelli I, Heath P, Shaw PJ, Kirby J. The involvement of regulatory T cells in amyotrophic lateral sclerosis and their therapeutic potential. Amyotrophic Lateral Sclerosis Frontotemporal Degen. 2020. https://doi.org/10.1080/21678421.2020.1752246.
  • Berry JD, Cudkowicz ME, Windebank AJ, Staff NP, Owegi M, Nicholson K, et al. NurOwn, phase 2, randomized, clinical trial in patients with ALS. Neurology. 2019;93:e2294–e2305.
  • Petrou P, Gothelf Y, Argov Z, Gotkine M, Levy YS, Kassis I, et al. Safety and clinical effects of mesenchymal stem cells secreting neurotrophic factor transplantation in patients with amyotrophic lateral sclerosis: results of phase 1/2 and 2a clinical Trials. JAMA Neurol. 2016;73:337–44.
  • Gravel M, Béland L-C, Soucy G, Abdelhamid E, Rahimian R, Gravel C, et al. IL-10 controls early microglial phenotypes and disease onset in als caused by misfolded superoxide dismutase 1. J Neurosci. 2016;36:1031–48.
  • Pennati A, Ng S, Wu Y, Murphy JR, Deng J, Rangaraju S, et al. Regulatory B cells induce formation of IL-10-expressing t cells in mice with autoimmune neuroinflammation. J Neurosci. 2016;36:12598–610.
  • Anderson WD, Greenhalgh AD, Takwale A, David S, Vadigepalli R. Novel influences of IL-10 on CNS inflammation revealed by integrated analyses of cytokine networks and microglial morphology. Front. Cell. Neurosci 2017;11. https://doi.org/10.3389/fncel.2017.00233
  • Pennati A, Asress S, Glass JD, Galipeau J. Adoptive transfer of IL-10+ regulatory B cells decreases myeloid-derived macrophages in the central nervous system in a transgenic amyotrophic lateral sclerosis model. Cell Mol Immunol. 2018;15:727–30.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.