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Biomarkers

FDG-PET shows weak correlation between focal motor weakness and brain metabolic alterations in ALS

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Pages 485-494 | Received 15 Dec 2022, Accepted 22 Jan 2023, Published online: 08 Feb 2023

References

  • Brown RH Jr, Al-Chalabi A. Amyotrophic lateral sclerosis. N Engl J Med. 2017;377:1602.
  • del Aguila MA, Longstreth WT Jr, McGuire V, Koepsell TD, van Belle G. Prognosis in amyotrophic lateral sclerosis: a population-based study. Neurology 2003;60:813–9.
  • Ringholz GM, Appel SH, Bradshaw M, Cooke NA, Mosnik DM, Schulz PE. Prevalence and patterns of cognitive impairment in sporadic ALS. Neurology 2005;65:586–90.
  • Chio A, Pagani M, Agosta F, Calvo A, Cistaro A, Filippi M. Neuroimaging in amyotrophic lateral sclerosis: insights into structural and functional changes. Lancet Neurol. 2014;13:1228–40.
  • van der Burgh HK, Westeneng H-J, Walhout R, van Veenhuijzen K, Tan HHG, Meier JM, et al. Multimodal longitudinal study of structural brain involvement in amyotrophic lateral sclerosis. Neurology 2020;94:e2592–604.
  • Menke RAL, Proudfoot M, Talbot K, Turner MR. The two-year progression of structural and functional cerebral MRI in amyotrophic lateral sclerosis. Neuroimage Clin. 2018;17:953–61.
  • Schmidt R, Verstraete E, de Reus MA, Veldink JH, van den Berg LH, van den Heuvel MP. Correlation between structural and functional connectivity impairment in amyotrophic lateral sclerosis. Hum Brain Mapp. 2014;35:4386–95.
  • Nasseroleslami B, Dukic S, Broderick M, Mohr K, Schuster C, Gavin B, et al. Characteristic increases in EEG connectivity correlate with changes of structural MRI in amyotrophic lateral sclerosis. Cereb Cortex. 2019;29:27–41.
  • Schulthess I, Gorges M, Müller H-P, Lulé D, Del Tredici K, Ludolph AC, et al. Functional connectivity changes resemble patterns of pTDP-43 pathology in amyotrophic lateral sclerosis. Sci Rep. 2016;6:38391.
  • Pagani M, Chiò A, Valentini MC, Öberg J, Nobili F, Calvo A, et al. Functional pattern of brain FDG-PET in amyotrophic lateral sclerosis. Neurology 2014;83:1067–74.
  • Van Laere K, Vanhee A, Verschueren J, De Coster L, Driesen A, Dupont P, et al. Value of 18fluorodeoxyglucose-positron-emission tomography in amyotrophic lateral sclerosis: a prospective study. JAMA Neurol. 2014;71:553–61.
  • Cistaro A, Pagani M, Montuschi A, Calvo A, Moglia C, Canosa A, et al. The metabolic signature of C9ORF72-related ALS: FDG PET comparison with nonmutated patients. Eur J Nucl Med Mol Imaging. 2014;41:844–52.
  • Kassubek J, Pagani M. Imaging in amyotrophic lateral sclerosis: MRI and PET. Curr Opin Neurol. 2019;32:740–6.
  • Agosta F, Altomare D, Festari C, Orini S, Gandolfo F, Boccardi M, et al. Clinical utility of FDG-PET in amyotrophic lateral sclerosis and Huntington’s disease. Eur J Nucl Med Mol Imaging. 2018;45:1546–56.
  • Chew S, Atassi N. Positron emission tomography molecular imaging biomarkers for amyotrophic lateral sclerosis. Front Neurol. 2019;10:135.
  • Peretti DE, Renken RJ, Reesink FE, de Jong BM, De Deyn PP, Dierckx RAJO, et al. Feasibility of pharmacokinetic parametric PET images in scaled subprofile modelling using principal component analysis. Neuroimage Clin. 2021;30:102625.
  • Meles SK, Vadasz D, Renken RJ, Sittig-Wiegand E, Mayer G, Depboylu C, et al. FDG PET, dopamine transporter SPECT, and olfaction: combining biomarkers in REM sleep behavior disorder. Mov Disord. 2017;32:1482–6.
  • Meles SK, Kok JG, De Jong BM, et al. The cerebral metabolic topography of spinocerebellar ataxia type 3. Neuroimage Clin 2018;19:90–7.
  • Sennfalt S, Klappe U, Thams S, et al. The path to diagnosis in ALS: delay, referrals, alternate diagnoses, and clinical progression. Amyotroph Lateral Scler Frontotemporal Degener 2023;24(1-2):45–53.
  • Longinetti E, Regodon Wallin A, Samuelsson K, et al. The Swedish motor neuron disease quality registry. Amyotroph Lateral Scler Frontotemporal Degener 2018;19:528–37.
  • Della Rosa PA, Cerami C, Gallivanone F, Prestia A, Caroli A, Castiglioni I, et al. A standardized [18F]-FDG-PET template for spatial normalization in statistical parametric mapping of dementia. Neuroinformatics 2014;12:575–93.
  • Signorini M, Paulesu E, Friston K, Perani D, Colleluori A, Lucignani G, et al. Rapid assessment of regional cerebral metabolic abnormalities in single subjects with quantitative and nonquantitative [18F]FDG PET: a clinical validation of statistical parametric mapping. Neuroimage. 1999;9:63–80.
  • Katz JS, Dimachkie MM, Barohn RJ. Amyotrophic lateral sclerosis: a historical perspective. Neurol Clin. 2015;33:727–34.
  • Rizzolatti G, Cattaneo L, Fabbri-Destro M, Rozzi S. Cortical mechanisms underlying the organization of goal-directed actions and mirror neuron-based action understanding. Physiol Rev. 2014;94:655–706.
  • Ravits JM, La Spada AR. ALS motor phenotype heterogeneity, focality, and spread: deconstructing motor neuron degeneration. Neurology 2009;73:805–11.