Is there a difference in clinicopathological outcomes of renal tumor between young and old patients? A multicenter matched-pair analysis

References

• Chow WH, Devesa SS, Warren JL, Fraumeni JF. Jr. Rising incidence of renal cell cancer in the United States. JAMA 1999;281:1628–31.
   PubMed Web of Science ®Google Scholar
• Jung KW, Won YJ, Kong HJ, Oh CM, Cho H, Lee DH, et al. Cancer statistics in Korea: incidence, mortality, survival, and prevalence in 2012. Cancer Res Treat 2015;47:127–41.
   PubMed Web of Science ®Google Scholar
• Cao Y, Paner GP, Perry KT, Flanigan RC, Campbell SC, Picken MM. Renal neoplasms in younger adults: analysis of 112 tumors from a single institution according to the new 2004 World Health Organization classification and 2002 American Joint Committee on Cancer Staging System. Arch Pathol Lab Med 2005;129:4874–91.
   Google Scholar
• Taccoen X, Valeri A, Descotes JL, Morin V, Stindel E, Doucet L, et al. Renal cell carcinoma in adults 40 years old or less: young age is an independent prognostic factor for cancer-specific survival. Eur Urol 2007;51:980–7.
   PubMed Web of Science ®Google Scholar
• Hofbauer SL, de Martino M, Seemann C, Zamani N, Lucca I, Haitel A, et al. Associations between presenting symptoms, clinicopathological parameters, and prognosis in a contemporary series of patients with renal cell carcinoma. Korean J Urol 2014;55:505–10.
   PubMedGoogle Scholar
• Sunela KL, Kataja MJ, Kellokumpu-Lehtinen PL. Changes in symptoms of renal cell carcinoma over four decades. BJU Int 2010;106:649–53.
   PubMed Web of Science ®Google Scholar
• Palsdottir HB, Hardarson S, Petursdottir V, Jonsson A, Jonsson E, Sigurdsson MI, et al. Incidental detection of renal cell carcinoma is an independent prognostic marker: results of a long-term, whole population study. J Urol 2012;187:48–53.
   PubMed Web of Science ®Google Scholar
• Sand KE, Hjelle KM, Rodge ÅJ, Gudbrandsđottir G, Bostad L, Beistand C. Incidentally detected renal cell carcinomas are highly associated with comorbidity and mortality unrelated to renal cell carcinoma. Scand J Urol 2013;47:462–71.
   PubMed Web of Science ®Google Scholar
• Thorstenson A, Bergman M, Scherman-Plogell AH, Hosseinnia S, Ljungberg B, Adolfsson J, et al. Tumour characteristics and surgical treatment of renal cell carcinoma in Sweden 2005-2010: a population-based study from the national Swedish kidney cancer register. Scand J Urol 2014;48:231–8.
   PubMed Web of Science ®Google Scholar
• Ljungberg B, Bensalah K, Canfield S, Dabestani S, Hofmann F, Hora M, et al. EAU guidelines on renal cell carcinoma: 2014 update. Eur Urol 2015;67:913–24.
   PubMed Web of Science ®Google Scholar
• Soultati A, Stares M, Swanton C, Larkin J, Turajlic S. How should clinicians address intratumour heterogeneity in clear cell renal cell carcinoma? Curr Opin Urol 2015;25:358–66.
   PubMed Web of Science ®Google Scholar
• de la Rochefordiere A, Asselain B, Campana F, Scholl SM, Fenton J, Vilcoq JR, et al. Age as prognostic factor in premenopausal breast carcinoma. Lancet 1993;341:1039–43.
   PubMed Web of Science ®Google Scholar
• Varma JR, Sample L. Colorectal cancer in patients aged less than 40 years. J Am Board Fam Pract 1990;3:54–9.
   PubMedGoogle Scholar
• Pectasides D, Fountzilas G, Aravantinos G, Bamias A, Kalofonos HP, Skarlos D, et al. Epithelial ovarian carcinoma in younger vs older women: is age an independent prognostic factor? The Hellenic oncology cooperative group experience. Int J Gynecol Cancer 2007;17:1003–10.
   PubMed Web of Science ®Google Scholar
• Chung M, Chang HR, Bland KI, Wanebo HJ. Younger women with breast carcinoma have a poorer prognosis than older women. Cancer 1996;77:97–103.
   PubMed Web of Science ®Google Scholar
• Gillett MD, Cheville JC, Karnes RJ, Lohse CM, Kwon ED, Leibovich BC, et al. Comparison of presentation and outcome for patients 18 to 40 and 60 to 70 years old with solid renal masses. J Urol 2005;173:1893–6.
   PubMed Web of Science ®Google Scholar
• Aziz A, May M, Zigeuner R, Pichler M, Chromecki T, Cindolo L, et al. Do young patients with renal cell carcinoma feature a distinct outcome after surgery? A comparative analysis of patient age based on the multinational CORONA database. J Urol 2014;191:310–15.
   PubMed Web of Science ®Google Scholar
• Goetzl MA, Desai M, Mansukhani M, Goluboff ET, Katz AE, Sawczuk IS, et al. Natural history and clinical outcome of sporadic renal cortical tumors diagnosed in the young adult. Urology 2004;63:41–5.
   PubMed Web of Science ®Google Scholar
• Denzinger S, Otto W, Burger M, Hammerschmied C, Junker K, Hartmann A, et al. Sporadic renal cell carcinoma in young and elderly patients: are there different clinicopathological features and disease specific survival rates? World J Surg Oncol 2007;5:16.
   PubMedGoogle Scholar
• Sánchez-Ortiz RF, Rosser CJ, Madsen LT, Swanson DA, Wood CG. Young age is an independent prognostic factor for survival of sporadic renal cell carcinoma. J Urol 2004;171:2160–5.
   PubMed Web of Science ®Google Scholar
• Jung EJ, Lee HJ, Kwak C, Ku JH, Moon KC. Young age is independent prognostic factor for cancer-specific survival of low-stage clear cell renal cell carcinoma. Urology 2009;73:137–41.
   PubMed Web of Science ®Google Scholar
• Kim JH, Seo SI, Song C, Chung J, Kwak C, Hong SH. Clinicohistological characteristics of renal cell carcinoma in children: a multicentre study. Can Urol Assoc J 2015;9:705.
   Web of Science ®Google Scholar
• Patard JJ, Leray E, Rioux-Leclercq N, Cindolo L, Ficarra V, Zisman A, et al. Prognostic value of histologic subtypes in renal cell carcinoma: a multicenter experience. J Clin Oncol 2005;23:2763–71.
   PubMed Web of Science ®Google Scholar
• Thompson RH, Ordonez MA, Iasonos A, Secin FP, Guillonneau B, Russo P, et al. Renal cell carcinoma in young and old patients – is there a difference? J Urol 2008;180:1262–6.
   PubMed Web of Science ®Google Scholar
• Klatte T, Han KR, Said JW, Böhm M, Allhoff EP, Kabbinavar FF, et al. Pathobiology and prognosis of chromophobe renal cell carcinoma. Urol Oncol 2008;26:604–9.
   PubMed Web of Science ®Google Scholar
• Motzer RJ, Bacik J, Mariani T, Russo P, Mazumdar M, Reuter V. Treatment outcome and survival associated with metastatic renal cell carcinoma of non-clear-cell histology. J Clin Oncol 2002;20:2376–81.
   PubMed Web of Science ®Google Scholar
• Volpe A, Novara G, Antonelli A, Bertini R, Billia M, Carmignani G, et al. Chromophobe renal cell carcinoma (RCC): oncological outcomes and prognostic factors in a large multicentre series. BJU Int 2012;110:76–83.
   PubMed Web of Science ®Google Scholar
• Skolarus TA, Serrano MF, Berger DA, Bullock TL, Yan Y, Humphrey PA, et al. The distribution of histological subtypes of renal tumors by decade of life using the 2004 WHO classification. J Urol 2008;179:439.
   PubMed Web of Science ®Google Scholar
• Lam JS, Shvarts O, Leppert JT, Figlin RA, Belldegrun AS. Renal cell carcinoma 2005: new frontiers in staging, prognostication and targeted molecular therapy. J Urol 2005;173:1853–62.
   PubMed Web of Science ®Google Scholar
• Siemer S, Lehmann J, Loch A, Becker F, Stein U, Schneider G, et al. Current TNM classification of renal cell carcinoma evaluated: revising stage T3a. J Urol 2005;173:33–7.
   PubMed Web of Science ®Google Scholar
• Schips L, Lipsky K, Zigeuner R, Salfellner M, Winkler S, Langner C, et al. Impact of tumor-associated symptoms on the prognosis of patients with renal cell carcinoma: a single-center experience of 683 patients. Urology 2003;62:1024–8.
   PubMed Web of Science ®Google Scholar
• Tsui KH, Shvarts O, Smith RB, Figlin R, de Kernion JB, Belldegrun A. Renal cell carcinoma: prognostic significance of incidentally detected tumors. J Urol 2000;163:426–30.
   PubMed Web of Science ®Google Scholar