Impact of postoperative phosphodiesterase type 5 inhibitor treatment on lower urinary tract symptoms after robot-assisted radical prostatectomy: a longitudinal study

References

• Sarma AV, Wei JT, Jacobson DJ, Dunn RL, Roberts RO, Girman CJ, et al. Comparison of lower urinary tract symptom severity and associated bother between community-dwelling black and white men: the Olmsted County Study of Urinary Symptoms and Health Status and the Flint Men’s Health Study. Urology 2003;61:1087–91.
   Web of Science ®Google Scholar
• Latz I, Weber M, Korda R, Smith D, Clements M, Patel M, et al. Lower urinary tract symptoms in relation to region of birth in 95,393 men living in Australia: the 45 and Up Study. World J Urol 2012;31:673–82.
   PubMed Web of Science ®Google Scholar
• Matsubara A, Yasumoto H, Teishima J, Seki M, Mita K, Hasegawa Y, et al. Lower urinary tract symptoms and risk of prostate cancer in Japanese men. Int J Urol 2006;13:1098–102.
   PubMed Web of Science ®Google Scholar
• Coyne KS, Sexton CC, Irwin DE, Kopp ZS, Kelleher CJ, Milsom I. The impact of overactive bladder, incontinence and other lower urinary tract symptoms on quality of life, work productivity, sexuality and emotional well-being in men and women: results from the EPIC study. BJU Int 2008;101:1388–95.
   PubMed Web of Science ®Google Scholar
• Heidenreich A, Bastian PJ, Bellmunt J, Bolla M, Joniau S, van der Kwast T, et al. EAU guidelines on prostate cancer. Part 1: screening, diagnosis, and local treatment with curative intent-update. Eur Urol 2014;65:124–37.
   PubMed Web of Science ®Google Scholar
• Sanda MG, Dunn RL, Michalski J, Sandler HM, Northouse L, Hembroff L, et al. Quality of life and satisfaction with outcome among prostate-cancer survivors. N Engl J Med 2008;358:1250–61.
   PubMed Web of Science ®Google Scholar
• Shao YH, Demissie K, Shih W, Mehta AR, Stein MN, Roberts CB, et al. Contemporary risk profile of prostate cancer in the United States. J Natl Cancer Inst 2009;101:1280–3.
   PubMed Web of Science ®Google Scholar
• Masters JG, Rice ML. Improvement in urinary symptoms after radical prostatectomy: a prospective evaluation of flow rates and symptom scores. BJU Int 2003;91:795–7.
   PubMed Web of Science ®Google Scholar
• Lepor H, Kaci L. The impact of open radical retropubic prostatectomy on continence and lower urinary tract symptoms: a prospective assessment using validated self-administered outcome instruments. J Urol 2004;171:1216–9.
   PubMed Web of Science ®Google Scholar
• Giannantoni A, Mearini E, Zucchi A, Constantini E, Mearini L, Bini V, et al. Bladder and urethral sphincter function after radical retropubic prostatectomy: a prospective long-term study. Eur Urol 2008;54:657–64.
   PubMed Web of Science ®Google Scholar
• Matsukawa Y, Hattori R, Komatsu T, Funahashi Y, Sassa N, Gotoh M. De novo detrusor underactivity after laparoscopic radical prostatectomy. Int J Urol 2010;17:643–8.
   PubMed Web of Science ®Google Scholar
• Barnoiu OS, Vozmediano-Chicharro R, García-Galisteo E, Soler-Martinez J, del Rosa-Samaniego JM, Machuca-Santacruz J, et al. Urodynamic assessment of bladder and urethral sphincter function before and after robot-assisted radial prostatectomy. Actas Urol Esp 2014;38:78–83.
   PubMed Web of Science ®Google Scholar
• Bannowsky A, Schulze H, van der Horst C, Hautmann S, Junemann KP. Recovery of erectile function after nerve-sparing radical prostatectomy: improvement with nightly low-dose sildenafil. BJU Int 2008;101:1279–83.
   PubMed Web of Science ®Google Scholar
• Montrosi F, Brock G, Lee J, Shapiro J, Van Poppel H, Graefen M, et al. Effect of nightly versus on-demand vardenafil on recovery of erectile function in men following bilateral nerve-sparing radical prostatectomy. Eur Urol 2008;54:924–31.
   PubMed Web of Science ®Google Scholar
• Waldkirch ES, Uckert S, Langnäse K, Richter K, Jonas U, Wolf G, et al. Immunohistochemical distribution of cyclic GMP-dependent protein kinase-1 in human prostate tissue. Eur Urol 2007;52:495–501.
   PubMed Web of Science ®Google Scholar
• Morelli A, Sarchielli E, Comeglio P, Fillippi S, Mancina R, Gacci M, et al. Phosphodiesterase type 5 expression in human and rat lower urinary tract tissues and the effect of tadalafil on prostate gland oxygenation in spontaneously hypertensive rats. J Sex Med 2011;8:2746–60.
   PubMed Web of Science ®Google Scholar
• Martinez-Salamanca JI, Carballido J, Eardley I, Giuliano F, Gratzke C, Rosen R, et al. Phosphodiesterase type 5 inhibitors in the management of non-neurogenic male lower urinary tract symptoms: critical analysis of current evidence. Eur Urol 2011;60:527–35.
   PubMed Web of Science ®Google Scholar
• Gacci M, Ierardi A, Rosen AD, Tazzioli S, Scapaticci E, Filippi S, et al. Vardenafil can improve continence recovery after bilateral nerve sparing prostatectomy: results of a randomized, double blind, placebo-controlled pilot study. J Sex Med 2010;7:234–43.
   PubMed Web of Science ®Google Scholar
• Tewari AK, Srivastava A, Huang MW, Robinson BD, Shevchuk MM, Durand M, et al. Anatomical grades of nerve sparing: a risk-stratified approach to neural-hammock sparing during robot-assisted radical prostatectomy (RARP). BJU Int 2011;108:984–92.
   PubMed Web of Science ®Google Scholar
• Roehrborn CG, Siami P, Barkin J, Damião R, Major-Walker K, Nandy I, et al. The effects of combination therapy with dutasteride and tamsulosin on clinical outcomes in men with symptomatic benign prostatic hyperplasia: 4-year results from the CombAT study. Eur Urol 2010;57:123–31.
   PubMed Web of Science ®Google Scholar
• Rosen R, Altwein J, Boyle P, Kirby RS, Lukacs B, Meuleman E, et al. Lower urinary tract symptoms and male sexual dysfunction: the multinational survey of the aging male (MSAM-7). Eur Urol 2003;44:637–49.
   PubMed Web of Science ®Google Scholar
• Hoesl CE, Woll EM, Burkart M, Altwein JE. Erectile dysfunction (ED) is prevalent, bothersome and underdiagnosed in patients consulting urologists for benign prostatic syndrome (BPS). Eur Urol 2005;47:511–7.
   PubMed Web of Science ®Google Scholar
• Truss MC, Stief CG, Uckert S, Becker AJ, Wefer J, Schultheiss D, et al. Phosphodiesterase 1 inhibition in the treatment of lower urinary tract dysfunction: from bench to bedside. World J Urol 2001;19:344–3.
   PubMed Web of Science ®Google Scholar
• Filippi S, Morelli A, Sandner P, Fibbi B, Mancina R, Marini M, et al. Characterization and functional role of androgen-dependent PDE5 activity in the bladder. Endocrinology 2007;148:1019–29.
   PubMed Web of Science ®Google Scholar
• Bittencourt JA, Tano T, Gajar SA, Resende AC, de Lemos Neto M, Damião R, et al. Relaxant effects of sildenafil on the human isolated bladder neck. Urology 2009;73:427–30.
   PubMed Web of Science ®Google Scholar
• Clegg EJ. The arterial supply of the human prostate and seminal vesicles. J Anat 1955;89:209–16.
   PubMed Web of Science ®Google Scholar
• Fibbi B, Morelli A, Vignozzi L, Filippi S, Chavalmane A, De Vita G, et al. Characterization of phosphodiesterase type 5 expression and functional activity in the human male lower urinary tract. J Sex Med 2010;7:59–69.
   PubMed Web of Science ®Google Scholar
• Sculptoreanu A, de Groat WC. Neurokinins enhance excitability in capsaicin-responsive DRG neurons. Exp Neurol 2007;205:92–100.
   PubMed Web of Science ®Google Scholar
• Yoshimura N, Seki S, de Groat WC. Nitric oxide modulates Ca(2+) channels in dorsal root ganglion neurons innervating rat urinary bladder. J Neurophysiol 2001;86:304–11.
   PubMed Web of Science ®Google Scholar
• Gandaglia G, Alberson M, Suardi N, Gallina A, Abdollah F, Castiglione F, et al. Postoperative phosphodiesterase type 5 inhibitor administration increases the rate of urinary continence recovery after bilateral nerve-sparing radical prostatectomy. Int J Urol 2013;20:413–9.
   PubMed Web of Science ®Google Scholar
• Ludovico GM, Dachille G, Pagliarulo G, D’Elia C, Mondaini N, Gacci M, et al. Bilateral nerve sparing robotic-assisted radical prostatectomy is associated with faster continence recovery but not with erectile function recovery compared with retropubic open prostatectomy: the need for accurate selection of patients. Oncol Rep 2013;29:2445–50.
   PubMed Web of Science ®Google Scholar