References
- Obesity and overweight [Internet]. [accessed 2020 Nov 3]. https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight.
- Blüher M. Obesity: global epidemiology and pathogenesis [Internet]. Nat Rev Endocrinol. Nature Publishing Group. 2019 [accessed 2020 Oct 30];15:1–11. doi:https://doi.org/10.1038/s41574-019-0176-8.
- Fan R, Wang J, Du J. Association between body mass index and fatty liver risk: a dose-response analysis. Sci Rep [Internet]]. 2018 Dec 1 [accessed 2020 Nov 3];8(1):1–7. www.nature.com/scientificreports/.
- Cercato C, Fonseca FA. Cardiovascular risk and obesity [Internet]. Diabetol Metab Syndr. BioMed Central Ltd. 2019 [accessed 2020 Nov 3];11:74. doi:https://doi.org/10.1186/s13098-019-0468-0.
- Ejerblad E, Fored CM, Lindblad P, Fryzek J, McLaughlin JK, Nyrén O. Obesity and risk for chronic renal failure. J Am Soc Nephrol [Internet]. 2006 Jun 1 [accessed 2020 Nov 3];17(6):1695–1702. www.jasn.org.
- Lega IC, Lipscombe LL. Review: diabetes, obesity, and cancer-pathophysiology and clinical implications [Internet]. . Endocr Rev; 2020 [accessed 2020 Nov 3];41(1); 33–52. https://academic.oup.com/edrv/article/41/1/33/5625127.
- Ellulu MS, Patimah I, Khaza’ai H, Rahmat A, Abed Y. Obesity & inflammation: the linking mechanism & the complications. Arch Med Sci [Internet]. 2017 [accessed 2020 Nov 3];13(4):851–863. /pmc/articles/PMC5507106/?report=abstract.
- Ye J. Emerging role of adipose tissue hypoxia in obesity and insulin resistance [Internet]. Int J Obes. NIH Public Access. 2009 [accessed 2020 Nov 3];33:54–66. doi:https://doi.org/10.1038/ijo.2008.229.
- Engin A The pathogenesis of obesity-associated adipose tissue inflammation. In: Advances in Experimental Medicine and Biology [Internet]. New York LLC: Springer; 2017 [accessed 2020 Nov 3]. 221–245. https://link.springer.com/chapter/10.1007/978-3-319-48382-5_9.
- Zhang C, Luo X, Zhang D, Deng B, Tong J, Zhang M, Chen L, Duan H, Niu W. Hypoxic adipocytes induce macrophages to release inflammatory cytokines that render skeletal muscle cells insulin resistant. Biochem Biophys Res Commun. 2020 Jan 15;521(3):625–631. doi:https://doi.org/10.1016/j.bbrc.2019.10.162.
- Marseglia L, Manti S, D’Angelo G, Nicotera A, Parisi E, Di Rosa G, Gitto E, Arrigo T. Oxidative stress in obesity: a critical component in human diseases [Internet]. Int J Molecular Sci MDPI AG. 2015 [accessed 2020 Nov 3];16:378–400. /pmc/articles/PMC4307252/?report=abstract.
- Matsushita K, Dzau VJ. Mesenchymal stem cells in obesity: insights for translational applications [Internet]. Laboratory Investigation. Nature Publishing Group. 2017 [accessed 2020 Oct 7];97:1158–1166. doi:https://doi.org/10.1038/labinvest.2017.42.
- Saleh F, Itani L, Calugi S, Grave RD, El Ghoch M. Adipose-derived mesenchymal stem cells in the treatment of obesity: a systematic review of longitudinal studies on preclinical evidence. Curr Stem Cell Res Ther [Internet]. 2018 May 15 [accessed 2018 Jun 8];13. http://www.ncbi.nlm.nih.gov/pubmed/29766824.
- Nauta AJ, Fibbe WE. Immunomodulatory properties of mesenchymal stromal cells [Internet]. Blood. 2007 [accessed 2020 Nov 3];110:3499–3506. https://pubmed.ncbi.nlm.nih.gov/17664353/.
- Iyer SS, Rojas M. Anti-inflammatory effects of mesenchymal stem cells: novel concept for future therapies. Expert Opin Biol Ther. 2008;8:569–581. doi:https://doi.org/10.1517/14712598.8.5.569.
- Rifai L, Saleh FA. Conventional and alternative mesenchymal stem cell therapies for the treatment of diabetes. In: advances in experimental medicine and biology [Internet]. Adv Exp Med Biol. 2020; accessed 2021 Mar 18. https://pubmed.ncbi.nlm.nih.gov/33385177/.
- Gir P, Oni G, Brown SA, Mojallal A, Rohrich RJ. Human adipose stem cells: current clinical applications [Internet]. Plast Reconstr Surg. 2012 [accessed 2020 Nov 3];129:1277–1290. https://pubmed.ncbi.nlm.nih.gov/22634645/.
- Alió JL, Alió Del Barrio JL, El Zarif M, Azaar A, Makdissy N, Khalil C, Harb W, El Achkar I, Jawad ZA, De Miguel MP, et al. Regenerative surgery of the corneal stroma for advanced keratoconus: 1-year outcomes. Am J Ophthalmol [Internet]. 2019 Jul 1 [accessed 2021 Jul 1];203:53–68. https://europepmc.org/article/med/30772348.
- Lucía Gutiérrez M, Guevara J, Alejandro Barrera L. Semi-automatic grading system in histologic and immunohistochemistry analysis to evaluate in vitro chondrogenesis [Internet]. Universitas Scientiarum. 2012 [accessed 2020 Dec 3]; 17. www.javeriana.edu.co/universitas_scientiarum.
- Khaodhiar L, McCowen KC, Blackburn GL. Obesity and its comorbid conditions. Clin Cornerstone. 1999 Jan 1;2(3):17–31. doi:https://doi.org/10.1016/S1098-3597(99)90002-9.
- Rong Y, Chun-Yan N, Hong-Xin Z, Lu Y, Wen W, Yu T. Association of adolescent obesity with nonalcoholic fatty liver disease and related risk factors in Xi’an, China. Ann Hepatol [Internet]. 2018 Jan 1 [accessed 2020 Nov 3];17(1):85–91. http://www.elsevier.es/en-revista-annals-hepatology-16-articulo-association-adolescent-obesity-with-nonalcoholic-S1665268119301103.
- Carbone S, Canada JM, Billingsley HE, Siddiqui MS, Elagizi A, Lavie CJ. Obesity paradox in cardiovascular disease: where do we stand? [Internet]. Vasc Health Risk Manag. Dove Medical Press Ltd. 2019 [accessed 2020 Nov 3];15:89–100. doi:https://doi.org/10.2147/VHRM.S168946.
- Kovesdy CP, Furth SL, Zoccali C. Obesity and kidney disease: hidden consequences of the epidemic [Internet]. Can J Kidney Health Dis. SAGE Publications Ltd. 2017 [cited 2020 Nov 3]; 4. Available from: /pmc/articles/PMC5433675/?report=abstract
- Mauvais-Jarvis F, Arnold AP, Reue KA. Guide for the design of pre-clinical studies on sex differences in metabolism [Internet]. Cell Metab. Cell Press. 2017 [accessed 2020 Oct 7];25:1216–1230. doi:https://doi.org/10.1016/j.cmet.2017.04.033.
- Lutz TA, Woods SC. Overview of animal models of obesity. Curr Protoc Pharmacol [Internet]. 2012 Sep [accessed 2020 Oct 7];58(Chapter 5\(SUPPL.58)). https://pubmed.ncbi.nlm.nih.gov/22948848/
- Barrett P, Mercer JG, Morgan PJ. Preclinical models for obesity research [Internet]. DMM Dis Models Mechanisms. Company of Biologists Ltd. 2016 [accessed 2020 Oct 7];9:1245–1255. doi:https://doi.org/10.1242/dmm.026443.
- Jaber H, Issa K, Eid A, Saleh FA. The therapeutic effects of adipose-derived mesenchymal stem cells on obesity and its associated diseases in diet-induced obese mice. Sci Rep [Internet]. 2021;11(1):6291. https://doi.org/10.1038/s41598-021-85917-9.
- Pais R, Barritt AS, Calmus Y, Scatton O, Runge T, Lebray P, Poynard T, Ratziu V, Conti F. NAFLD and liver transplantation: current burden and expected challenges. J Hepatol. 2016;65(6):1245–1257. doi:https://doi.org/10.1016/j.jhep.2016.07.033.
- Mitra S, De A, Chowdhury A. Epidemiology of non-alcoholic and alcoholic fatty liver diseases. Trans Gastroenterol Hepatol. 2020;5:16. doi:https://doi.org/10.21037/tgh.2019.09.08.
- Wang H, Zhang H, Huang B, Miao G, Yan X, Gao G, Luo Y, Chen H, Chen W, Yang L. Mesenchymal stem cells reverse high-fat diet-induced non-alcoholic fatty liver disease through suppression of CD4+ T lymphocytes in mice. Mol Med Rep [Internet]. 2018 Mar 1 [accessed 2020 Nov 3];17(3).3769–3774. http://www.spandidos-publications.com/10.3892/mmr.2017.8326/abstract.
- Altunkaynak ME, Özbek E, Altunkaynak BZ, Can İ, Unal D, Unal B. The effects of high-fat diet on the renal structure and morphometric parametric of kidneys in rats. J Anat [Internet]]. 2008 Jun 1 [accessed 2021 Mar 18];212(6):845–852. doi:https://doi.org/10.1111/j.1469-7580.2008.00902.x.
- Wicks SE, Nguyen TT, Breaux C, Kruger C, Stadler K. Diet-induced obesity and kidney disease - In search of a susceptible mouse model. Biochimie [Internet]. 2016 May 1 [accessed 2020 Nov 3];124:65–73. https://pubmed.ncbi.nlm.nih.gov/26248309/.
- Yu S, Cheng Y, Zhang L, Yin Y, Xue J, Li B, Gong Z, Gao J, Mu Y. Treatment with adipose tissue-derived mesenchymal stem cells exerts anti-diabetic effects, improves long-term complications, and attenuates inflammation in type 2 diabetic rats. Stem Cell Res Ther [Internet]. 2019 Nov 20 [accessed 2020 Nov 4];10(1).1–18. https://link.springer.com/articles/10.1186/s13287-019-1474–8.
- Coelho-Filho OR, Shah RV, Mitchell R, Neilan TG, Moreno H, Simonson B, Kwong R, Rosenzweig A, Das S, Jerosch-Herold M, et al. Quantification of cardiomyocyte hypertrophy by cardiac magnetic resonance: implications for early cardiac remodeling. Circulation [Internet]. 2013 Sep 10 [accessed 2020 Nov 4];128(11):1225–1233. https://pubmed.ncbi.nlm.nih.gov/23912910/.
- Wang Z, Li L, Zhao H, Peng S, Zuo Z. Chronic high fat diet induces cardiac hypertrophy and fibrosis in mice. Metabolism [Internet]. 2015 [accessed 2020 Nov 4];64(8):917–925. https://pubmed.ncbi.nlm.nih.gov/25982698/.
- Daltro PS, Barreto BC, Silva PG, Neto PC, PHF SF, Santana Neta D, Carvalho GB, Silva DN, Paredes BD, de Alcantara AC et al. Therapy with mesenchymal stromal cells or conditioned medium reverse cardiac alterations in a high-fat diet–induced obesity model. Cytotherapy. 2017 Oct 1;19(10):1176–1188. doi:https://doi.org/10.1016/j.jcyt.2017.07.002.
- Kern L, Mittenbühler MJ, Vesting AJ, Ostermann AL, Wunderlich CM, Wunderlich FT. Obesity-induced TNFα and IL-6 signaling: the missing link between obesity and inflammation- driven liver and colorectal cancers [Internet]. Cancers. MDPI AG. 2019 [accessed 2020 Dec 4];11. /pmc/articles/PMC6356226/?report=abstract.
- Goyal R, Faizy AF, Siddiqui SS, Singhai M. Evaluation of TNF-α and IL-6 levels in obese and non-obese diabetics: pre- and postinsulin effects. N Am J Med Sci [Internet]. 2012 Apr 11 [accessed 2020 Dec 4];4(4):180–184. /pmc/articles/PMC3334258/?report=abstract.