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An update clinical application of amniotic fluid-derived stem cells (AFSCs) in cancer cell therapy and tissue engineering

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Pages 765-774 | Received 17 May 2016, Accepted 21 Jul 2016, Published online: 10 Aug 2016

References

  • Aghi M, Cho TC, Chiocca EA, Kramm CM, Breakefield XO. 1998. Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/cytosine deaminase gene therapies. J Natl Cancer Inst 90:370–380.
  • Anderson LM, Krotz S, Weitzman SA, Thimmapaya B. 2000. Breast cancer-specific expression of the Candida albicans cytosine deaminase gene using a transcriptional targeting approach. Cancer Gene Ther 7:845–852.
  • Bitsika V, Roubelakis MG, Zagoura D, Trohatou O, Makridakis M, Pappa KI, et al. 2011. Human amniotic fluid-derived mesenchymal stem cells as therapeutic vehicles: a novel approach for the treatment of bladder cancer. Stem Cells Dev 21:1097–1111.
  • Bollini S, Cheung KK, Riegler J, Dong X, Smart N, Ghionzoli M, et al. 2011a. Amniotic fluid stem cells are cardioprotective following acute myocardial infarction. Stem Cells Dev 20:1985–1994.
  • Bollini S, Pozzobon M, Nobles M, Riegler J, Dong X, Piccoli M, et al. 2011b. In vitro and in vivo cardiomyogenic differentiation of amniotic fluid stem cells. Stem Cell Rev Rep 7:364–380.
  • Bossolasco P, Montemurro T, Cova L, Zangrossi S, Calzarossa C, Buiatiotis S, et al. 2006a. Molecular and phenotypic characterization of human amniotic fluid cells and their differentiation potential. Cell Res 16:329–336.
  • Bossolasco P, Montemurro T, Cova L, Zangrossi S, Calzarossa C, Buiatiotis S, et al. 2006b. Molecular and phenotypic characterization of human amniotic fluid cells and their differentiation potential. Cell Res 16:329–336.
  • Brace RA. 1986. Amniotic fluid volume and its relationship to fetal fluid balance: review of experimental data. Semin Perinatol 10:103–112.
  • Calvet G, Aguiar RS, Melo AS, Sampaio SA, De Filippis I, Fabri A, et al. 2016. Detection and sequencing of Zika virus from amniotic fluid of fetuses with microcephaly in Brazil: a case study. Lancet Infect Dis 16:653–660.
  • Carlsson PO, Korsgren O, Le Blanc K. 2015. Mesenchymal stromal cells to halt the progression of type 1 diabetes? Curr Diab Rep 15:46. doi: 10.1007/s11892-015-0616-3.
  • Chiavegato A, Bollini S, Pozzobon M, Callegari A, Gasparotto L, Taiani J, et al. 2007. Human amniotic fluid-derived stem cells are rejected after transplantation in the myocardium of normal, ischemic, immuno-suppressed or immuno-deficient rat. J Mol Cell Cardiol 42:746–759.
  • Chung SS, Koh CJ. 2013. Bladder cancer cell in co-culture induces human stem cell differentiation to urothelial cells through paracrine FGF10 signaling. In Vitro Cell Dev Biol-Anim 49:746–751.
  • Cipriani S, Bonini D, Marchina E, Balgkouranidou I, Caimi L, Grassi Zucconi G, Barlati S. 2007. Mesenchymal cells from human amniotic fluid survive and migrate after transplantation into adult rat brain. Cell Biol Int 31: 845–850.
  • Da Sacco S, Sedrakyan S, Boldrin F, Giuliani S, Parnigotto P, Habibian R, et al. 2010. Human amniotic fluid as a potential new source of organ specific precursor cells for future regenerative medicine applications. J Urol 183: 1193–1200.
  • De Coppi P, Bartsch G, Siddiqui MM, Xu T, Santos CC, Perin L, et al. 2007a. Isolation of amniotic stem cell lines with potential for therapy. Nat Biotechnol 25:100–106.
  • De Coppi P, Callegari A, Chiavegato A, Gasparotto L, Piccoli M, Taiani J, et al. 2007b. Amniotic fluid and bone marrow derived mesenchymal stem cells can be converted to smooth muscle cells in the cryo-injured rat bladder and prevent compensatory hypertrophy of surviving smooth muscle cells. J Urol 177: 369–376.
  • Dobreva MP, Pereira P, Deprest J, Zwijsen A. 2010. On the origin of amniotic stem cells: of mice and men. Int J Dev Biol 54:761–777.
  • Duenhoelter JH, Pritchard JA. 1976. Fetal respiration: quantitative measurements of amnionic fluid inspired near term by human and rhesus fetuses. Am J Obstet Gynecol 125:306–309.
  • Eberli D, Atala A. 2006. Tissue engineering using adult stem cells. Method Enzymol 420: 287–302.
  • Fauza D. 2004. Amniotic fluid and placental stem cells. Best Pract Res Clin Obstet Gynaecol 18:877–891.
  • Gholizadeh-Ghalehaziz S, Farahzadi R, Fathi E, Pashaiasl M. 2015. A mini overview of isolation, characterization and application of amniotic fluid stem cells. Int J Stem Cells 8:115–120.
  • Gosden CM. 1983. Amniotic fluid cell types and culture. Br Med Bull 39:348–354.
  • Graham CD, Fauza DO. 2007. Isolation of mesenchymal stem cells from amniotic fluid and placenta. Curr Protoc Stem Cell Biol 1E. 2.1–1E. 2.14.
  • Granero-Molto F, Weis JA, Longobardi L, Spagnoli A. 2008. Role of mesenchymal stem cells in regenerative medicine: application to bone and cartilage repair. Expert Opin Biol Ther 8:255–268.
  • Grskovic M, Javaherian A, Strulovici B, Daley GQ. 2011. Induced pluripotent stem cells-opportunities for disease modelling and drug discovery. Nat Rev Drug Discov 10:915–929.
  • Haldi M, Ton C, Seng WL, McGrath P. 2006. Human melanoma cells transplanted into zebrafish proliferate, migrate, produce melanin, form masses and stimulate angiogenesis in zebrafish. Angiogenesis 9:139–151.
  • Han Y, Tao R, Sun T, Chai J, Xu G, Liu J. 2012. Advances and opportunities for stem cell research in skin tissue engineering. Eur Rev Med Pharmacol Sci 16:1873–1877.
  • Hauser PV, De Fazio R, Bruno S, Sdei S, Grange C, Bussolati B, Benedetto C, Camussi G. 2010. Stem cells derived from human amniotic fluid contribute to acute kidney injury recovery. Am J Pathol 177:2011–2021.
  • Heldring N, Mäger I, Wood MJ, Le Blanc K, Andaloussi SE. 2015. Therapeutic potential of multipotent mesenchymal stromal cells and their extracellular vesicles. Hum Gene Ther 26:506–517.
  • Hendrix MJ, Seftor EA, Seftor RE, Kasemeier-Kulesa J, Kulesa PM, Postovit LM. 2007. Reprogramming metastatic tumour cells with embryonic microenvironments. Nat Rev Cancer 7:246–255.
  • Hoehn H, Salk D. 1982. Morphological and biochemical heterogeneity of amniotic fluid cells in culture. Methods Cell Biol 26:11–34.
  • In ‘T Anker PS, Scherjon SA, Kleijburg-Van Der Keur C, De Groot-Swings GM, Claas FH, Fibbe WE, Kanhai HH. 2004. Isolation of mesenchymal stem cells of fetal or maternal origin from human placenta. Stem Cells 22:1338–1345.
  • Jiao H, Guan F, Yang B, Li J, Song L, Hu X, Du Y. 2012. Human amniotic membrane derived-mesenchymal stem cells induce C6 glioma apoptosis in vivo through the Bcl-2/caspase pathways. Mol Biol Rep 39:467–473.
  • Joo S, Ko IK, Atala A, Yoo JJ, Lee SJ. 2012. Amniotic fluid-derived stem cells in regenerative medicine research. Arch Pharmacal Res 35:271–280.
  • Kang N, Hwang K, Kim S, Kim Y, Hyun S, Jeung E, Choi K. 2012a. Potential antitumor therapeutic strategies of human amniotic membrane and amniotic fluid-derived stem cells. Cancer Gene Ther 19:517–522.
  • Kang N, Hwang K, Yi B, Lee H, Jeung E, Kim S, Choi K. 2012b. Human amniotic fluid-derived stem cells expressing cytosine deaminase and thymidine kinase inhibits the growth of breast cancer cells in cellular and xenograft mouse models. Cancer Gene Ther 19:412–419.
  • Kaviani A, Perry TE, Dzakovic A, Jennings RW, Ziegler MM, Fauza DO. 2001. The amniotic fluid as a source of cells for fetal tissue engineering. J Pediatr Surg 36:1662–1665.
  • Kern S, Eichler H, Stoeve J, Klüter H, Bieback K. 2006. Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue. Stem Cells 24:1294–1301.
  • Kim J, Lee Y, Kim H, Hwang K, Kwon H, Kim S, et al. 2007. Human amniotic fluid-derived stem cells have characteristics of multipotent stem cells. Cell Prolif 40:75–90.
  • KIM KY, Kim SU, Leung PC, Jeung EB, Choi KC. 2010. Influence of the prodrugs 5-fluorocytosine and CPT-11 on ovarian cancer cells using genetically engineered stem cells: tumor-tropic potential and inhibition of ovarian cancer cell growth. Cancer Sci 101:955–962.
  • Kim SU, Jeung EB, Kim YB, Cho MH, Choi KC. 2011. Potential tumor-tropic effect of genetically engineered stem cells expressing suicide enzymes to selectively target invasive cancer in animal models. Anticancer Res 31:1249–1258.
  • Kobayashi M, Yakuwa T, Sasaki K, Sato K, Kikuchi A, Kamo I, Yokoyama Y, Sakuragawa N. 2008. Multilineage potential of side population cells from human amnion mesenchymal layer. Cell Transplant 17:291–301.
  • Kolambkar YM, Peister A, Soker S, Atala A, Guldberg RE. 2007. Chondrogenic differentiation of amniotic fluid-derived stem cells. J Mol Histol 38:405–413.
  • Kovach TK, Dighe AS, Lobo PI, Cui Q. 2015. Interactions between MSCs and immune cells: implications for bone healing. J Immunol Res 2015:752510. doi: 10.1155/2015/752510.
  • La Marca-Ghaemmaghami P, Dainese SM, La Marca R, Zimmermann R, Ehlert U. 2015. The acute autonomic stress response and amniotic fluid glucocorticoids in second-trimester pregnant women. Psychosom Med 77:41–49.
  • Lai E. 2010. Regenerative medicine at early echelons: changing medical care & outcomes. DTIC Document.
  • Lee LM, Seftor EA, Bonde G, Cornell RA, Hendrix MJ. 2005. The fate of human malignant melanoma cells transplanted into zebrafish embryos: assessment of migration and cell division in the absence of tumor formation. Dev Dynam 233:1560–1570.
  • Li L, Li S, Cai T, Wang H, Xie X, Liu Z, Zhang Y. 2016. The targeted inhibitory effects of human amniotic fluid stem cells carrying CXCR4 promoter and DAL-1 on non-small cell lung carcinoma growth. Gene Ther 23:214–222.
  • Li L, Wang D, Zhou J, Cheng Y, Liang T, Zhang G. 2015. Characteristics of human amniotic fluid mesenchymal stem cells and their tropism to human ovarian cancer. PLoS One 10:e0123350. doi: 10.1371/journal.pone.0123350.
  • Lloyd‐Griffith C, Duffy GP, O’Brien FJ. 2015. Investigating the effect of hypoxic culture on the endothelial differentiation of human amniotic fluid‐derived stem cells. J Anat 227:767–780.
  • Loukogeorgakis SP, De Coppi P. 2016. Stem cells from amniotic fluid–Potential for regenerative medicine. Best Pract Res Clin Obstet Gynaecol 31:45–57.
  • Luo H, Huang X, Huang F, Liu X. 2011. Preliminary study on transdifferentiation of human amniotic epithelial cells and its intrasplenic transplantation. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 25:144–148.
  • Manuelpillai U, Tchongue J, Lourensz D, Vaghjiani V, Samuel CS, Liu A, Williams ED, Sievert W. 2010. Transplantation of human amnion epithelial cells reduces hepatic fibrosis in immunocompetent CCl4-treated mice. Cell Transplant 19:1157–1168.
  • Maraldi T, Bertoni L, Riccio M, Zavatti M, Carnevale G, Resca E, et al. 2014. Human amniotic fluid stem cells: neural differentiation in vitro and in vivo. Cell Tissue Res 357:1–13.
  • Marongiu F, Gramignoli R, Dorko K, Miki T, Ranade AR, Paola Serra M, et al. 2011. Hepatic differentiation of amniotic epithelial cells. Hepatology 53:1719–1729.
  • Méndez-Ferrer S, Michurina TV, Ferraro F, Mazloom AR, Macarthur BD, Lira SA, et al. 2010. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature 466:829–834.
  • Minei LJ, Suzuki K. 1976. Role of fetal deglutition and micturition in the production and turnover of amniotic fluid in the monkey. Obstet Gynecol 48:177–181.
  • Moorefield EC, Delo DM, De Coppi P, Atala A. 2010. Amniotic fluid and placental stem cells. Pluripotent Stem Cells. New York: Nova Science. pp. 113–135.
  • Murakami M, Hayashi Y, Iohara K, Osako Y, Hirose Y, Nakashima M. 2015. Trophic effects and regenerative potential of mobilized mesenchymal stem cells from bone marrow and adipose tissue as alternative cell sources for pulp/dentin regeneration. Cell Transplant 24:1753–1765.
  • Nazari-Shafti TZ, Bruno IG, Martinez RF, Coleman ME, Alt EU, McClure SR. 2015. High yield recovery of equine mesenchymal stem cells from umbilical cord matrix/Wharton’s jelly using a semi-automated process. Methods Mol Biol 1235:131–146.
  • Parolini O, Soncini M, Evangelista M, Schmidt D. 2009. Amniotic membrane and amniotic fluid-derived cells: potential tools for regenerative medicine? Regen Med 4:275–291.
  • Pashaiasl M, Khodadadi K, Kayvanjoo AH, Pashaei-Asl R, Ebrahimie E, Ebrahimi M. 2016. Unravelling evolution of Nanog, the key transcription factor involved in self-renewal of undifferentiated embryonic stem cells, by pattern recognition in nucleotide and tandem repeats characteristics. Gene 578:194–204.
  • Perin L, Sedrakyan S, Da Sacco S, De Filippo R. 2008. Characterization of human amniotic fluid stem cells and their pluripotential capability. Methods Cell Biol 86:85–99.
  • Perin L, Sedrakyan S, Giuliani S, Da Sacco S, Carraro G, Shiri L, et al. 2010. Protective effect of human amniotic fluid stem cells in an immunodeficient mouse model of acute tubular necrosis. PLoS One 5:e9357.
  • Phermthai T, Odglun Y, Julavijitphong S, Titapant V, Chuenwattana P, Vantanasiri C, Pattanapanyasat K. 2010. A novel method to derive amniotic fluid stem cells for therapeutic purposes. BMC Cell Biol 11:79.
  • Pipino C, Pandolfi A. 2015. Osteogenic differentiation of amniotic fluid mesenchymal stromal cells and their bone regeneration potential. World J Stem Cells 7:681.
  • Postovit LM, Margaryan NV, Seftor EA, Kirschmann DA, Lipavsky A, Wheaton WW, et al. 2008. Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells. Proc Natl Acad Sci U.S.A. 105:4329–4334.
  • Prentice DA. 2006. Current science of regenerative medicine with stem cells. J Investig Med 54:33–37.
  • Priest R, Marimuthu K, Priest J. 1978. Origin of cells in human amniotic fluid cultures: ultrastructural features. Lab Invest 39:106–109.
  • Prusa AR, Hengstschlager M. 2002. Amniotic fluid cells and human stem cell research: a new connection. Med. Sci. Monit 8:RA253–RA257.
  • Prusa AR, Marton E, Rosner M, Bettelheim D, Lubec G, Pollack A, Bernaschek G, Hengstschläger M. 2004. Neurogenic cells in human amniotic fluid. Am J Obstet Gynecol 191:309–314.
  • Prusa AR, Marton E, Rosner M, Bernaschek G, Hengstschläger M. 2003. Oct-4-expressing cells in human amniotic fluid: a new source for stem cell research? Human Reprod 18:1489–1493.
  • Rezania A. 2015. Differentiation of human embryonic stem cells. US Patent 20,150,191,700.
  • Rosser AE, Zietlow R, Dunnett SB. 2007. Stem cell transplantation for neurodegenerative diseases. Curr Opin Neurol 20:688–692.
  • Roubelakis MG, Pappa KI, Bitsika V, Zagoura D, Vlahou A, Papadaki HA, Antsaklis A, Anagnou NP. 2007. Molecular and proteomic characterization of human mesenchymal stem cells derived from amniotic fluid: comparison to bone marrow mesenchymal stem cells. Stem Cells Dev 16:931–952.
  • Scherjon SA, Kleijburg-Van Der Keur C, Noort WA, Claas FH, Willemze R, Fibbe WE, Kanhai HH. 2003. Amniotic fluid as a novel source of mesenchymal stem cells for therapeutic transplantation. Blood 102:1548–1549.
  • Schiller PC, D’Ippolito G. 2014. Non-expanded post-natal multilineage-inducible cells. Google Patents.
  • Sessarego N, Parodi A, Podestà M, Benvenuto F, Mogni M, Raviolo V, et al. 2008. Multipotent mesenchymal stromal cells from amniotic fluid: solid perspectives for clinical application. Haematologica 93:339–346.
  • Shaw SWS, David AL, De Coppi P. 2011. Clinical applications of prenatal and postnatal therapy using stem cells retrieved from amniotic fluid. Curr Opin Obstet Gynecol 23:109–116.
  • Shinagawa K, Kitadai Y, Yuge R, Onoyama M, Tanaka S, Yasui W, Chayama K. 2015. Treatment with regorafenib inhibits the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic nude mice model of colon cancer. Cancer Res 75:5068–5068.
  • Skardal A, Mack D, Kapetanovic E, Atala A, Jackson JD, Yoo J, Soker S. 2012. Bioprinted amniotic fluid-derived stem cells accelerate healing of large skin wounds. Stem Cells Transl Med 1:792.
  • Spinelli V, Guillot PV, De Coppi P. 2013. Induced pluripotent stem (iPS) cells from human fetal stem cells (hFSCs). Organogenesis 9:101–110.
  • Steigman SA, Fauza DO. 2007. Isolation of mesenchymal stem cells from amniotic fluid and placenta. Curr Protoc Stem Cell Biol. doi: 10.1002/9780470151808.sc01e02s1.
  • Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S. 2007. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131:861–872.
  • Toda A, Okabe M, Yoshida T, Nikaido T. 2007. The potential of amniotic membrane/amnion-derived cells for regeneration of various tissues. J Pharmacol Sci 105:215–228.
  • Todorov P, Petrova N, Mihova A, Guenova M, Arabadzhiev B, Hristova E. 2015. The female age influences the expression of pluripotent stem cells markers in human ovarian cells. C R Acad Bulg Sci 68:65–70.
  • Topczewska JM, Postovit LM, Margaryan NV, Sam A, Hess AR, Wheaton WW, et al. 2006. Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness. Nature Med 12:925–932.
  • Toselli M, Cerbai E, Rossi F, Cattaneo E. 2008. Do amniotic fluid-derived stem cells differentiate into neurons in vitro? Nat Biotechnol 26:269–270.
  • Tsai MS, Lee JL, Chang YJ, Hwang SM. 2004. Isolation of human multipotent mesenchymal stem cells from second‐trimester amniotic fluid using a novel two‐stage culture protocol. Human Reprod 19:1450–1456.
  • Underwood MA, Gilbert WM, Sherman MP. 2005. Amniotic fluid: not just fetal urine anymore. J Perinatol 25:341–348.
  • Vallier L, Alexander M, Pedersen R. 2007. Conditional gene expression in human embryonic stem cells. Stem Cells 25:1490–1497.
  • Wolbank S, Peterbauer A, Fahrner M, Hennerbichler S, Van Griensven M, Stadler G, Redl H, Gabriel C. 2007. Dose-dependent immunomodulatory effect of human stem cells from amniotic membrane: a comparison with human mesenchymal stem cells from adipose tissue. Tissue Eng 13:1173–1183.
  • Xu B, Ji X, Chen X, Yao M, Han X, Chen M, Tang W, Xia Y. 2015. Effect of perfluorooctane sulfonate on pluripotency and differentiation factors in mouse embryoid bodies. Toxicology 328:160–167.
  • Yi BR, Kang NH, Hwang KA, Kim SU, Jeung EB, Kim YB, Heo GJ, Choi KC. 2011. Genetically engineered stem cells expressing cytosine deaminase and interferon-β migrate to human lung cancer cells and have potentially therapeutic anti-tumor effects. Int J Oncol 39:833–839.
  • Zani A, Cananzi M, Fascetti-Leon F, Lauriti G, Smith VV, Bollini S, et al. 2013. Amniotic fluid stem cells improve survival and enhance repair of damaged intestine in necrotising enterocolitis via a COX-2 dependent mechanism. Gut 63:300–309.
  • Zhang D, Jiang M, Miao D. 2011. Transplanted human amniotic membrane-derived mesenchymal stem cells ameliorate carbon tetrachloride-induced liver cirrhosis in mouse. PLoS One 6:e16789.
  • Zhou J, Wang D, Liang T, Guo Q, Zhang G. 2014. Amniotic fluid-derived mesenchymal stem cells: characteristics and therapeutic applications. Arch Gynecol Obstet 290:223–231.

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