1,983
Views
17
CrossRef citations to date
0
Altmetric
Original Articles

Microemulsions based on paeonol-menthol eutectic mixture for enhanced transdermal delivery: formulation development and in vitro evaluation

, , , , &
Pages 1241-1246 | Received 13 Jul 2016, Accepted 11 Aug 2016, Published online: 07 Sep 2016

References

  • Alkrad JA, Mrestani Y, Neubert RH. 2016. Development and characterization of microemulsions containing hyaluronic acid. Eur J Pharm Sci. 86:84–90.
  • Alvarado HL, Abrego G, Souto EB, Garduño-Ramirez ML, Clares B, García ML, Calpena AC. 2015. Nanoemulsions for dermal controlled release of oleanolic and ursolic acids: in vitro, ex vivo and in vivo characterization. Colloids Surf B Biointerfaces. 130:40–47.
  • Aroso IM, Silva JC, Mano F, Ferreira AS, Dionisio M, Sá-Nogueira I, et al. 2016. Dissolution enhancement of active pharmaceutical ingredients by therapeutic deep eutectic systems. Eur J Pharm Biopharm. 98:57–66.
  • Boonme P, Krauel K, Graf A, Rades T, Junyaprasert VB. 2006. Characterization of microemulsion structures in the pseudoternary phase diagram of isopropyl palmitate/water/brij 97:1-butanol. AAPS PharmSciTech. 7:E1–E6.
  • Cherukuvada S, Nangia A. 2014. Eutectics as improved pharmaceutical materials: design, properties and characterization. Chem Commun. 50:906–923.
  • Chun MK, Hossain K, Choi SH, Ban SJ, Moon H, Choi HK. 2012. Development of cataplasmic transdermal drug delivery system containing eutectic mixture of lidocaine and prilocaine. J Pharma Investig. 42:139–146.
  • Luo M, Shen Q, Chen J. 2011. Transdermal delivery of paeonol using cubic gel and microemulsion gel. Int J Nanomed. 6:1603–1610.
  • Morrison HG, Sun CC, Neervannan S. 2009. Characterization of thermal behavior of deep eutectic solvents and their potential as drug solubilization vehicles. Int J Pharm. 378:136–139.
  • Negi P, Singh B, Sharma G, Beg S, Raza K, Katare OP. 2016. Phospholipid microemulsion-based hydrogel for enhanced topical delivery of lidocaine and prilocaine: QbD-based development and evaluation. Drug Deliv. 23:951–967.
  • Paradkar M, Thakkar V, Soni T, Gandhi T, Gohel M. 2015. Formulation and evaluation of clotrimazole transdermal spray. Drug Dev Ind Pharm. 41:1718–1725.
  • Park CW, Kim JY, Rhee YS, Oh TO, Ha JM, Choi NY, et al. 2012. Preparation and valuation of a topical solution containing eutectic mixture of itraconazole and phenol. Arch Pharm Res. 35:1935–1943.
  • Pillai AB, Nair JV, Gupta NK, Gupta S. 2015. Microemulsion-loaded hydrogel formulation of butenafine hydrochloride for improved topical delivery. Arch Dermatol Res. 307:625–633.
  • Shen Q, Li X, Li W, Zhao X. 2011. Enhanced intestinal absorption of daidzein by borneol/menthol eutectic mixture and microemulsion. AAPS PharmSciTech. 12:1044–1049.
  • Stott PW, Williams AC, Barry BW. 1998. Transdermal delivery from eutectic systems: enhanced permeation of a model drug, ibuprofen. J Control Release. 50:297–308.
  • Tarate B, Bansal AK. 2015. Characterization of CoQ 10-lauric acid eutectic system. Thermochim Acta. 605:100–106.
  • Wang Z, Pal R. 2014. Enlargement of nanoemulsion region in pseudo-ternary mixing diagrams for a drug delivery system. J Surfact Deterg. 17:49–58.
  • Xu Z, Jin J, Zheng M, Xu X, Liu Y, Wang X. 2016. Co-surfactant free microemulsions: preparation, characterization and stability evaluation for food application. Food Chem. 204:194–200.
  • Yong CS, Jung SH, Rhee JD, Choi HG, Lee BJ, Kim DC, Choi YW, Kim CK. 2003. Improved solubility and in vitro dissolution of Ibuprofen from poloxamer gel using eutectic mixture with menthol. Drug Deliv. 10:179–183.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.