References
- Chang MH, Fung HB. Besifloxacin: a topical fluoroquinolone for the treatment of bacterial conjunctivitis. Clin Ther. 2010;32:454–471.
- O’Brien TP. Besifloxacin ophthalmic suspension, 0.6%: a novel topical fluoroquinolone for bacterial conjunctivitis. Adv Ther. 2012;29:473–490.
- Haas W, Pillar CM, Zurenko GE, et al. Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria. Antimicrob Agents Chemother. 2009;53:3552–3560.
- Haas W, Gearinger LS, Usner DW, et al. Integrated analysis of three bacterial conjunctivitis trials of besifloxacin ophthalmic suspension, 0.6%: etiology of bacterial conjunctivitis and antibacterial susceptibility profile. Clin Ophthalmol. 2011;5:1369–1379.
- Haas W, Pillar CM, Torres M, et al. Monitoring antibiotic resistance in ocular microorganisms: results from the antibiotic resistance monitoring in ocular microrganisms (ARMOR) 2009 surveillance study. Am J Ophthalmol. 2011;152:567–574.
- Asbell PA, Sanfilippo CM, Pillar CM, et al. Antibiotic resistance among ocular pathogens in the United States: five-year results from the antibiotic resistance monitoring in ocular microorganisms (ARMOR) surveillance study. JAMA Ophthalmol. 2015;133:1445–1454.
- Tarabishy AB, Jeng BH. Bacterial conjunctivitis: a review for internists. Cleve Clin J Med. 2008;75:507–512.
- Alvarez-Lorenzo C, Yanez F, Barreiro-Iglesias R, et al. Imprinted soft contact lenses as norfloxacin delivery systems. J Control Rel. 2006;113:236–244.
- De Campos AM, Sanchez A, Alonso MJ. Chitosan nanoparticles: a new vehicle for the improvement of the delivery of drugs to the ocular surface. Application to cyclosporin A. Int J Pharm. 2001;224:159–168.
- Lin HH, Ko SM, Hsu LR, et al. The preparation of norfloxacin-loaded liposomes and their in-vitro evaluation in pig’s eye. J Pharm Pharmacol. 1996;48:801–805.
- Gratieri T, Gelfuso GM, de Freitas OD, et al. Enhancing and sustaining the topical ocular delivery of fluconazole using chitosan solution and poloxamer/chitosan in situ forming Gel. Eur J Pharm Biopharm. 2011;79:320–327.
- Thimmasetty MK, Mandal S, Prabhushankar GL, et al. Formulation and evaluation of an in situ gel-forming ophthalmic formulation of moxifloxacin hydrochloride. Int J Pharm Investig. 2012;2:78–82.
- Vijaya C, Goud KS. Ion-activated in situ gelling ophthalmic delivery systems of azithromycin. Indian J Pharm Sci. 2011;73:615–620.
- Majithiya RJ, Ghosh PK, Umrethia ML, et al. Thermoreversible-mucoadhesive gel for nasal delivery of sumatriptan. AAPS PharmSciTech. 2006;7:67.
- Agrawal AK, Das M, Jain S. In situ gel systems as' smart' carriers for sustained ocular drug delivery. Expert Opin Drug Deliv. 2012;9:383–402.
- Reed K, Li A, Wilson B, et al. Enhancement of ocular in situ gelling properties of low acyl gellan gum by use of ion exchange. J Ocul Pharmacol Ther. 2016;32:574–582.
- Cao Y, Zhang C, Shen W, et al. Poly(N-isopropylacrylamide)-chitosan as thermosensitive in situ gel-forming system for ocular drug delivery. J Control Release. 2007;120:186–194.
- Tang YF, Du YM, Hu XW, et al. Rheological characterisation of a novel thermosensitive chitosan/poly (vinyl alcohol) blend hydrogel. Carbohydrate Polym. 2007;67:491–499.
- Agrawal AK, Gupta PN, Khanna A, et al. Development and characterization of in situ gel system for nasal insulin delivery. Pharmazie. 2010;65:188–193.
- Ameeduz Z, Ali J, Bhatnagar A, et al. Chitosan nanoparticles amplify the ocular hypotensive effect of carteolol in rabbits. Int J Biol Macromol. 2014;65:479–491.
- Ameeduz Z, Ali J, Khan N, et al. Carteolol loaded corboxymethyl tamarind kernel polysaccharide nanoparticles for ophthalmic delivery: box-behnken design, in vitro, ex vivo assessment. Sci Adv Mater. 2014;6:1–13.
- Kortejarvi H, Yliperttula M, Dressman JB. Bio waiver monographs for immediate release solid oral dosage forms: ranitidine hydrochloride. J Pharm Sci. 2005;94:1617–1625.
- Khan N, Ameeduzzafar Aqil M, et al. Development and evaluation of a novel in situ gel of sparfloxacin for sustained ocular drug delivery: in vitro and ex vivo characterization . Pharm Dev Technol. 2015;20:662–669.
- Costa MC, Barden AT, Andrade JM, et al. Quantitative evaluation of besifloxacin ophthalmic suspension by HPLC, application to bioassay method and cytotoxicity studies. Talanta 2014;119:367–374.
- INVITOX. Frame, data bank of in vitro techniques in toxicology: hen’s eg test, INVITOX Protocol 15; Ergatt/Frame; 1990.
- Vinardell MP, Maciancomparative M. Comparative study of the HET-CAM test and the Draize eye test for assessment of irritancy potential. Toxcol In Vitro. 1994;8:467.
- ICH Q2R1. Topic Q2 (R1): Validation of analytical procedures: text and methodology International Conference on Harmonization, Geneva, Switzerland; 2005.
- Jiang Y, Meng X, Wu Z, et al. Modified chitosan thermosensitive hydrogel enables sustained and efficient anti-tumor therapy via intratumoral injection. Carbohydr Polym. 2016;144:245–253.
- Chenite A, Chaput C, Wang D, et al. Novel injectable neutral solutions of chitosan form biodegradable gels in situ. Biomaterials. 2000;21:2155–2161.
- Maruoka S, Matsuura T, Kawasaki K, et al. Biocompatibility of polyvinylalcohol gel as a vitreous substitute. Curr Eye Res. 2006;31:599–606.
- Duan Y, Cai X, Du H, et al. Novel in situ gel systems based on P123/TPGS mixed micelles and gellan gum for ophthalmic delivery of curcumin. Colloids Surf B Biointerfaces. 2015;1(128):322–330.
- Gupta H, Velpandian T, Jain S. Ion- and pH-activated novel in-situ gel system for sustained ocular drug delivery. J Drug Target. 2010;18:499–505.
- Geethalakshmi A, Karki R, Jha SK, et al. Sustained ocular delivery of brimonidine tartrate using ion activated in situ gelling system. Curr Drug Deliv. 2012;9:197–204.
- Khafagy ES, Morishita M, Onuki Y, et al. Current challenges in non-invasive insulin delivery systems: a comparative review. Adv Drug Del Review. 2007;59:1521–1546.