KLF16 suppresses human glioma cell proliferation and tumourigenicity by targeting TFAM

References

• Mischel PS, Cloughesy TF. Targeted molecular therapy of GBM. Brain Pathol. 2003;13:52–61.
   PubMed Web of Science ®Google Scholar
• Feng H, Hu B, Jarzynka MJ, et al. Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis. Proc Natl Acad Sci USA. 2012;109:3018–3023.
   PubMed Web of Science ®Google Scholar
• Maher EA, Furnari FB, Bachoo RM, et al. Malignant glioma: genetics and biology of a grave matter. Genes Dev. 2001;15:1311–1333.
   PubMed Web of Science ®Google Scholar
• Cancer Genome Atlas Research N. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature. 2008;455:1061–1068.
   PubMed Web of Science ®Google Scholar
• Zhu Y, Parada LF. The molecular and genetic basis of neurological tumours. Nat Rev Cancer. 2002;2:616–626.
   PubMed Web of Science ®Google Scholar
• Wang Y, Jiang T. Understanding high grade glioma: molecular mechanism, therapy and comprehensive management. Cancer Lett. 2013;331:139–146.
   PubMed Web of Science ®Google Scholar
• Tetreault MP, Yang Y, Katz JP. Kruppel-like factors in cancer. Nat Rev Cancer. 2013;13:701–713.
   PubMed Web of Science ®Google Scholar
• McConnell BB, Yang VW. Mammalian Krüppel-like factors in health and diseases. Physiol Rev. 2010;90:1337–1381.
   PubMed Web of Science ®Google Scholar
• Chen C, Benjamin MS, Sun X, et al. KLF5 promotes cell proliferation and tumorigenesis through gene regulation and the TSU-Pr1 human bladder cancer cell line. Int J Cancer. 2006;118:1346–1355.
   PubMed Web of Science ®Google Scholar
• Mori A, Moser C, Lang SA, et al. Up-regulation of Kruppel-like factor 5 in pancreatic cancer is promoted by interleukin-1beta signaling and hypoxia-inducible factor-1alpha. Mol Cancer Res. 2009;7:1390–1398.
   PubMed Web of Science ®Google Scholar
• Takagi K, Miki Y, Onodera Y, et al. Kruppel-like factor 5 in human breast carcinoma: a potent prognostic factor induced by androgens. Endocr Relat Cancer. 2012;19:741–750.
   PubMed Web of Science ®Google Scholar
• Kremer-Tal S, Reeves HL, Narla G, et al. Frequent inactivation of the tumor suppressor Kruppel-like factor 6 (KLF6) in hepatocellular carcinoma. Hepatology. 2004;40:1047–1052.
   PubMed Web of Science ®Google Scholar
• Narla G, Heath KE, Reeves HL, et al. KLF6, a candidate tumor suppressor gene mutated in prostate cancer. Science. 2001;294:2563–2566.
   PubMed Web of Science ®Google Scholar
• Reeves HL, Narla G, Ogunbiyi O, et al. Kruppel-like factor 6 (KLF6) is a tumor-suppressor gene frequently inactivated in colorectal cancer. Gastroenterology. 2004;126:1090–1103.
   PubMed Web of Science ®Google Scholar
• Li Q, Gao Y, Jia Z, et al. Dysregulated Kruppel-like factor 4 and vitamin D receptor signaling contribute to progression of hepatocellular carcinoma. Gastroenterology. 2012;143:799–810.
   PubMed Web of Science ®Google Scholar
• Zhang N, Zhang J, Shuai L, et al. Kruppel-like factor 4 negatively regulates beta-catenin expression and inhibits the proliferation, invasion and metastasis of gastric cancer. Int J Oncol. 2012;40:2038–2048.
   PubMed Web of Science ®Google Scholar
• Yu T, Chen X, Zhang W, et al. Regulation of the potential marker for intestinal cells, Bmi1, by beta-catenin and the zinc finger protein KLF4: implications for colon cancer. J Biol Chem. 2012;287:3760–3768.
   PubMed Web of Science ®Google Scholar
• Hu W, Hofstetter WL, Li H, et al. Putative tumor-suppressive function of Kruppel-like factor 4 in primary lung carcinoma. Clin Cancer Res. 2009;15:5688–5695.
   PubMed Web of Science ®Google Scholar
• Wei D, Wang L, Kanai M, et al. KLF4alpha up-regulation promotes cell cycle progression and reduces survival time of patients with pancreatic cancer. Gastroenterology. 2010;139:2135–2145.
   PubMed Web of Science ®Google Scholar
• Simmen RC, Pabona JM, Velarde MC, et al. The emerging role of Krüppel-like factors in endocrine-responsive cancers of female reproductive tissues. J Endocrinol. 2010;204:223–231.
   PubMed Web of Science ®Google Scholar
• Kang L, Lu B, Xu J, et al. Downregulation of Krüppel-like factor 9 in human colorectal cancer. Pathol Int. 2008;58:334–338.
   PubMed Web of Science ®Google Scholar
• Zhang XL, Zhang D, Michel FJ, et al. Selective interactions of Kruppel-like factor 9/basic transcription element-binding protein with progesterone receptor isoforms A and B determine transcriptional activity of progesterone-responsive genes in endometrial epithelial cells. J Biol Chem. 2003;278:21474–21482.
   PubMed Web of Science ®Google Scholar
• Velarde MC, Zeng Z, McQuown JR, et al. Kruppel-like factor 9 is a negative regulator of ligand-dependent estrogen receptor alpha signaling in Ishikawa endometrial adenocarcinoma cells. Mol Endocrinol. 2007;21:2988–3001.
   PubMedGoogle Scholar
• Miller IJ, Bieker JJ. A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Kruppel family of nuclear proteins. Mol Cell Biol. 1993;13:2776–2786.
   PubMed Web of Science ®Google Scholar
• Shields JM, Yang VW. Identification of the DNA sequence that interacts with the gut-enriched Krüppel-like factor. Nucleic Acids Res. 1998;26:796–802.
   PubMed Web of Science ®Google Scholar
• Warda M, Kim HK, Kim N, et al. A matter of life, death and diseases: mitochondria from a proteomic perspective. Expert Rev Proteomics. 2013;10:97–111.
   PubMed Web of Science ®Google Scholar
• Uchiumi T, Kang D. The role of TFAM-associated proteins in mitochondrial RNA metabolism. Biochim Biophys Acta. 2012;1820:565–570.
   PubMed Web of Science ®Google Scholar
• Cheng Z, Ristow M. Mitochondria and metabolic homeostasis. Antioxid Redox Signal. 2013;19:240–242.
   PubMed Web of Science ®Google Scholar
• Lee H, Park J, Tran Q, et al. Mitochondrial transcription factor A (TFAM) is upregulated in glioma. Mol Med Rep. 2017;15:3781–3786.
   PubMed Web of Science ®Google Scholar
• Yoshida T, Azuma H, Aihara K, et al. Vascular smooth muscle cell proliferation is dependent upon upregulation of mitochondrial transcription factor A (mtTFA) expression in injured rat carotid artery. Atherosclerosis. 2005;178:39–47.
   PubMed Web of Science ®Google Scholar
• Wang J, Galvao J, Beach KM, et al. Novel roles and mechanism for Krüppel-like factor 16 (KLF16) regulation of neurite outgrowth and ephrin receptor A5 (EphA5) expression in retinal ganglion cells. J Biol Chem. 2016;291:21422.
   PubMed Web of Science ®Google Scholar
• Wang J, Galvao J, Beach KM, et al. Novel roles and mechanism for Krüppel-like factor 16 (KLF16) regulation of neurite outgrowth and Ephrin receptor A5 (EphA5) expression in retinal ganglion cells. J Biol Chem. 2016;291:18084–18095.
   PubMed Web of Science ®Google Scholar
• Kim AJ, Jee HJ, Song N, et al. p21(WAF¹/C¹P¹) deficiency induces mitochondrial dysfunction in HCT116 colon cancer cells. Biochem Biophys Res Commun. 2013;430:653–658.
   PubMed Web of Science ®Google Scholar
• Guo J, Zheng L, Liu W, et al. Frequent truncating mutation of TFAM induces mitochondrial DNA depletion and apoptotic resistance in microsatellite-unstable colorectal cancer. Cancer Res. 2011;71:2978–2987.
   PubMed Web of Science ®Google Scholar