Improved oxygen storage capacity of haemoglobin submicron particles by one-pot formulation

References

• Zhang Y, Chan HF, Leong KW. Advanced materials and processing for drug delivery: the past and the future. Adv Drug Deliv Rev. 2013;65:104–120.
   PubMed Web of Science ®Google Scholar
• Teekamp N, Duque LF, Frijlink HW, et al. Production methods and stabilization strategies for polymer-based nanoparticles and microparticles for parenteral delivery of peptides and proteins. Expert Opin Drug Deliv. 2015;12:1311–1331.
   PubMed Web of Science ®Google Scholar
• Keshani S, Daud WRW, Nourouzi MM, et al. Spray drying: an overview on wall deposition, process and modeling. J Food Eng. 2015;146:152–162.
   Web of Science ®Google Scholar
• Vehring R. Pharmaceutical particle engineering via spray drying. Pharm Res. 2008;25:999–1022.
   PubMed Web of Science ®Google Scholar
• Gao X, Zhang X, Wu Z, et al. Synthesis and physicochemical characterization of a novel amphiphilic polylactic acid-hyperbranched polyglycerol conjugate for protein delivery. J Control Release. 2009;140:141–147.
   PubMed Web of Science ®Google Scholar
• Bäumler H, Xiong Y, Liu ZZ, et al. Novel hemoglobin particles-promising new-generation hemoglobin-based oxygen carriers. Artif Organs. 2014;38:708–714.
   PubMed Web of Science ®Google Scholar
• Xiong Y, Steffen A, Andreas K, et al. Hemoglobin-based oxygen carrier microparticles: synthesis, properties, and in vitro and in vivo investigations. Biomacromolecules. 2012;13:3292–3300.
   PubMed Web of Science ®Google Scholar
• Ba¨umler H, Georgieva R. Coupled enzyme reactions in multicompartment microparticles. Biomacromolecules. 2010;11:1480–1487.
   PubMed Web of Science ®Google Scholar
• Habeeb AFSA, Hiramoto R. Reaction of proteins with glutaraldehyde. Arch Biochem Biophys. 1968;126:16–26.
   PubMed Web of Science ®Google Scholar
• Lai J-Y. Interrelationship between cross-linking structure, molecular stability, and cytocompatibility of amniotic membranes cross-linked with glutaraldehyde of varying concentrations. RSC Adv. 2014;4:18871–18880.
   Web of Science ®Google Scholar
• Reddy N, Reddy R, Jiang Q. Crosslinking biopolymers for biomedical applications. Trends Biotechnol. 2015;33:362–369.
   PubMed Web of Science ®Google Scholar
• Sommermeyer K, Eichner W, inventor. Haemoglobin-hydroxyethyl starch conjugates as oxygen carriers. United States patent US 6,083,909, Assignee: Fresenius AG, Oberusel, Germany; 2000
   Google Scholar
• Eike JH, Palmer AF. Oxidized mono-, di-, tri-, and polysaccharides as potential hemoglobin cross-linking reagents for the synthesis of high oxygen affinity artificial blood substitutes. Biotechnol Prog. 2004;20:953–962.
   PubMed Web of Science ®Google Scholar
• Scatena R, Giardina B. O-raffinose-polymerised haemoglobin. A biochemical and pharmacological profile of an oxygen carrier. Expert Opin Biol Ther. 2001;1:121–127.
   PubMed Web of Science ®Google Scholar
• Boykins RA, Buehler PW, Jia Y, et al. O-raffinose crosslinked hemoglobin lacks site-specific chemistry in the central cavity: structural and functional consequences of beta93Cys modification. Proteins Struct Funct Genet. 2005;59:840–855.
   PubMed Web of Science ®Google Scholar
• Bonneaux F, Labrude P, Dellacherie E. Preparation and oxygen binding properties of soluble covalent hemoglobin-dextran conjugates. Experientia. 1981;37(8):884–886.
   PubMedGoogle Scholar
• Bonneaux F, Dellacherie E, Labrude P, et al. Hemoglobin-dialdehyde dextran conjugates: improvement of their oxygen-binding properties with anionic groups [Internet]. J Protein Chem. 1996;15:461.
   PubMedGoogle Scholar
• McCahon R, Hardman J. Pharmacology of plasma expanders [Internet]. In: Nick P, Mick S, editors. Anaesthesia and intensive care medicine. Vol. 18. Netherlands: Elsevier Amsterdam; 2017. p. 418–420.
   Google Scholar
• Mehvar R. Dextrans for targeted and sustained delivery of therapeutic and imaging agents. J Control Release. 2000;69:1–25.
   PubMed Web of Science ®Google Scholar
• Maia J, Evangelista MB, Gil H, et al. Dextran-based materials for biomedical applications. Carbohydr Appl Med. 2014;661:31–53.
   Google Scholar
• Maia J, Carvalho RA, Coelho JFJ, et al. Insight on the periodate oxidation of dextran and its structural vicissitudes. Polymer (Guildf). 2011;52:258–265.
   Web of Science ®Google Scholar
• Wasiak I, Kulikowska A, Janczewska M, et al. Dextran nanoparticle synthesis and properties. PLoS One 2016. 11(1): e0146237. doi:10.1371/journal.pone.0146237
   PubMed Web of Science ®Google Scholar
• Lisman A, Butruk B, Wasiak I, et al. Dextran/albumin hydrogel sealant for Dacron(R) vascular prosthesis. J Biomater Appl. 2014;28:1386–1396.
   PubMed Web of Science ®Google Scholar
• Cortesi R, Esposito E, Osti M, et al. Dextran cross-linked gelatin microspheres as a drug delivery system. Eur J Pharm Biopharm. 1999;47:153–160.
   PubMed Web of Science ®Google Scholar
• Palmer AF, Sun G, Harris DR. Tangential flow filtration of hemoglobin. Biotechnol Prog. 2009;25:189–199.
   PubMed Web of Science ®Google Scholar
• Haney CR, Buehler PW, Gulati A. Purification and chemical modifications of hemoglobin in developing hemoglobin based oxygen carriers. Adv Drug Deliv Rev. 2000;40:153–169.
   PubMed Web of Science ®Google Scholar
• Berillo D, Elowsson L, Kirsebom H. Oxidized dextran as crosslinker for chitosan cryogel scaffolds and formation of polyelectrolyte complexes between chitosan and gelatin. Macromol Biosci. 2012;12:1090–1099.
   PubMed Web of Science ®Google Scholar
• Muangsiri W, Kirsch LE. The protein-binding and drug release properties of macromolecular conjugates containing daptomycin and dextran. Int J Pharm. 2006;315:30–43.
   PubMed Web of Science ®Google Scholar
• Xiong Y, Liu ZZ, Georgieva R, et al. Nonvasoconstrictive hemoglobin particles as oxygen carriers. ACS Nano. 2013;7:7454–7461.
   PubMed Web of Science ®Google Scholar
• Xiong Y, Georgieva R, Steffen A, et al. Structure and properties of hybrid biopolymer particles fabricated by co-precipitation cross-linking dissolution procedure. J Colloid Interface Sci. 2018;514:156–164.
   PubMed Web of Science ®Google Scholar
• Haldane J. The ferricyanide method of determining the oxygen capacity of blood. J Physiol (Lond). 1900;25:295–302.
   Google Scholar
• Cook SF. The action of potassium cyanide and potassium ferricyanide on certain respiratory pigments. J Gen Physiol. 1928;11:339–348.
   PubMedGoogle Scholar
• Bäumler H, Hamberger L, Zaslansky P, et al. Non-destructive mechanical testing of allograft bone-implants by analytic centrifugation. Exp Mech. 2016;56:1653–1660.
   Web of Science ®Google Scholar
• Kao I, Xiong Y, Steffen A, et al. Preclinical in vitro safety investigations of submicron sized hemoglobin based oxygen carrier HbMP-700. Artif Organs. 2018;42:549–559.
   PubMed Web of Science ®Google Scholar
• Gómez-Mascaraque LG, Méndez JA, Fernández-Gutiérrez M, et al. Oxidized dextrins as alternative crosslinking agents for polysaccharides: application to hydrogels of agarose–chitosan. Acta Biomater. 2014;10:798–811.
   PubMed Web of Science ®Google Scholar
• Ribeiro MP, Morgado PI, Miguel SP, et al. Dextran-based hydrogel containing chitosan microparticles loaded with growth factors to be used in wound healing. Mater Sci Eng C. 2013;33:2958–2966.
   PubMed Web of Science ®Google Scholar
• Fuentes M, Segura RL, Abian O, et al. Determination of protein-protein interactions through aldehyde-dextran intermolecular cross-linking. Proteomics. 2004;4:2602–2607.
   PubMed Web of Science ®Google Scholar
• Wang Y, Zhang S, Zhang J, et al. Structural, functional and physiochemical properties of dextran-bovine hemoglobin conjugate as a hemoglobin-based oxygen carrier. Process Biochem. 2017;60:67–73.
   Web of Science ®Google Scholar
• Zhang J, Wang Y, You G-X, et al. Conjugation with 20 kDa dextran decreases the autoxidation rate of bovine hemoglobin. Artif Cells Nanomed Biotechnol. 2018;46:1436–1438.
   PubMed Web of Science ®Google Scholar
• Guillochon D, Vijayalakshmi MW, Thiam-Sow A, et al. Effect of glutaraldehyde on hemoglobin: functional aspects and Mössbauer parameters. Biochem Cell Biol. 1986;64:29–37.
   PubMed Web of Science ®Google Scholar
• Mayer A, Vadon M, Rinner B, et al. The role of nanoparticle size in hemocompatibility. Toxicology. 2009;258:139–147.
   PubMed Web of Science ®Google Scholar