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Research Article

The survival benefit of adjuvant radiotherapy for pathological T4N2M0 colon cancer in the Modern Chemotherapy Era: evidence from the SEER database 2004–2015

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Pages 834-840 | Received 31 Oct 2019, Accepted 17 Jan 2020, Published online: 27 May 2020

References

  • Ferlay J, Colombet M, Soerjomataram I, et al. Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods. Int J Cancer. 2019;144(8):1941–1953.
  • Siegel RL, Miller KD, Jemal A. Cancer Statistics, 2019. CA Cancer J Clin. 2019;69(1):7–34.
  • Rosander E, Nordenvall C, Sjovall A, et al. Management and outcome after multivisceral resections in patients with locally advanced primary colon cancer. Dis Colon Rectum. 2018;61(4):454–460.
  • McLaughlin C, Kim NK, Bandyopadhyay D, et al. Adjuvant radiation therapy for T4 non-rectal colon adenocarcinoma provides a cause-specific survival advantage: a SEER database analysis. Radiother Oncol. 2019;133:50–53.
  • Smith CA, Kachnic LA. Evolving treatment paradigm in the treatment of locally advanced rectal cancer. J Natl Compr Canc Netw. 2018;16(7):909–915.
  • Peeters KC, Marijnen CA, Nagtegaal ID, et al. The TME trial after a median follow-up of 6 years: increased local control but no survival benefit in irradiated patients with resectable rectal carcinoma. Ann Surg. 2007;246(5):693–701.
  • Bonnetain F, Bosset JF, Gerard JP, et al. What is the clinical benefit of preoperative chemoradiotherapy with 5FU/leucovorin for T3-4 rectal cancer in a pooled analysis of EORTC 22921 and FFCD 9203 trials: surrogacy in question?. Eur J Cancer. 2012;48(12):1781–1790.
  • Ludmir EB, Arya R, Wu Y, et al. Role of adjuvant radiotherapy in locally advanced colonic carcinoma in the modern chemotherapy era. Ann Surg Oncol. 2016;23(3):856–862.
  • Willett CG, Fung CY, Kaufman DS, et al. Postoperative radiation therapy for high-risk colon carcinoma. J Clin Oncol. 1993;11(6):1112–1117.
  • Krishnamurty DM, Hawkins AT, Wells KO, et al. Neoadjuvant radiation therapy in locally advanced colon cancer: a cohort analysis. J Gastrointest Surg. 2018;22(5):906–912.
  • Martenson JJ, Willett CG, Sargent DJ, et al. Phase III study of adjuvant chemotherapy and radiation therapy compared with chemotherapy alone in the surgical adjuvant treatment of colon cancer: results of intergroup protocol 0130. J Clin Oncol. 2004;22(16):3277–3283.
  • Cukier M, Smith AJ, Milot L, et al. Neoadjuvant chemoradiotherapy and multivisceral resection for primary locally advanced adherent colon cancer: a single institution experience. Eur J Surg Oncol. 2012;38(8):677–682.
  • Huang CM, Huang MY, Ma CJ, Yeh Y, et al. Neoadjuvant FOLFOX chemotherapy combined with radiotherapy followed by radical resection in patients with locally advanced colon cancer. Radiat Oncol. 2017;12(1):48.
  • Govindarajan A, Coburn NG, Kiss A, et al. Population-based assessment of the surgical management of locally advanced colorectal cancer. J Natl Cancer Inst. 2006;98(20):1474–1481.
  • Croner RS, Merkel S, Papadopoulos T, et al. Multivisceral resection for colon carcinoma. Dis Colon Rectum. 2009;52(8):1381–1386.
  • Hawkins AT, Ford MM, Geiger TM, et al. Neoadjuvant radiation for clinical T4 colon cancer: a potential improvement to overall survival. Surgery. 2019;165(2):469–475.
  • Mendenhall WM, Amos EH, Rout WR, et al. Adjuvant postoperative radiotherapy for colon carcinoma. Cancer. 2004;101(6):1338–1344.
  • Chang GJ, Rodriguez-Bigas MA, Skibber JM, et al. Lymph node evaluation and survival after curative resection of colon cancer: systematic review. J Natl Cancer Inst. 2007;99(6):433–441.
  • Ceelen W, Van Nieuwenhove Y, Pattyn P. Prognostic value of the lymph node ratio in stage iii colorectal cancer: a systematic review. Ann Surg Oncol. 2010;17(11):2847–2855.
  • Taieb J, Tabernero J, Mini E, et al. Oxaliplatin, fluorouracil, and leucovorin with or without cetuximab in patients with resected stage III colon cancer (PETACC-8): an open-label, randomised phase 3 trial. Lancet Oncol. 2014;15(8):862–873.