279
Views
0
CrossRef citations to date
0
Altmetric
Original Articles

Chronic subjective dizziness among an aging population is associated with amyloid positron emission tomography and neuropsychiatric symptoms

ORCID Icon

References

  • Sloane PD, Hartman M, Mitchell CM. Psychological factors associated with chronic dizziness in patients aged 60 and older. J Am Geriatr Soc. 1994;42(8):847–852.
  • Tinetti ME, Williams CS, Gill TM. Dizziness among older adults: a possible geriatric syndrome. Ann Intern Med. 2000;132(5):337–344.
  • Hatsuta H, Takao M, Ishii K, et al. Amyloid β accumulation assessed with 11C-Pittsburgh compound B PET and postmortem neuropathology. Curr Alzheimer Res. 2015;12(3):278–286.
  • Mintun MA, LaRossa GN, Sheline YI, et al. [11C]PIB in a nondemented population. Neurology. 2006;67(3):446–452.
  • Resnick SM, Sojkova J, Zhou Y, et al. Longitudinal cognitive decline is associated with fibrillar amyloid-beta measured by [11C]PiB. Neurology. 2010;74(10):807–815.
  • Kamil RJ, Bilgel M, Wong DF, et al. Vestibular function and beta-amyloid deposition in the baltimore longitudinal study of aging. Front Aging Neurosci. 2018;10:408–408.
  • Petersen RC, Roberts RO, Knopman DS, et al. Prevalence of mild cognitive impairment is higher in men. The Mayo Clinic Study Aging. 2010;75(10):889–897.
  • Roberts RO, Geda YE, Knopman DS, et al. The Mayo clinic study of aging: design and sampling, participation, baseline measures and sample characteristics. Neuroepidemiology. 2008;30(1):58–69.
  • St Sauver JL, Grossardt BR, Yawn BP, et al. Use of a medical records linkage system to enumerate a dynamic population over time: the Rochester epidemiology project. Am J Epidemiol. 2011;173(9):1059–1068.
  • Kokmen E, Smith GE, Petersen RC, et al. The short test of mental status. Correlations with standardized psychometric testing. Arch Neurol. 1991;48(7):725–728.
  • Petersen RC. Mild cognitive impairment as a diagnostic entity. J Intern Med. 2004;256(3):183–194.
  • American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. Washington (DC): American Psychiatric Association; 1994.
  • Kaufer DI, Cummings JL, Ketchel P, et al. Validation of the NPI-Q, a brief clinical form of the neuropsychiatric inventory. J Neuropsychiatry Clin Neurosci. 2000;12(2):233–239.
  • Grant MM. Beck anxiety inventory. In: Goldstein S & Naglieri JA, editors. Encyclopedia of child behavior and development. Boston (MA): Springer US; 2011. pp. 215–217.
  • Upton J. Beck depression inventory (BDI). In: Gellman MD & JR Turner, editors. Encyclopedia of behavioral medicine. New York, NY: Springer New York; 2013. pp. 178–179.
  • Jacobson GP, Piker EG, Hatton K, et al. Development and preliminary findings of the dizziness symptom profile. Ear Hear. 2019;40(3):568–576.
  • Dieterich M, Staab JP. Functional dizziness: from phobic postural vertigo and chronic subjective dizziness to persistent postural-perceptual dizziness. Curr Opin Neurol. 2017;30(1):107–113.
  • Kelm Z, Klapchar K, Kieliszak CR, et al. Psychogenic dizziness: an important but overlooked differential diagnosis in the workup of the dizzy patient. J Am Osteopath Assoc. 2018;118(5):e22–e27.
  • Bensamoun D, Guignard R, Furst AJ, et al. Associations between neuropsychiatric symptoms and cerebral amyloid deposition in cognitively impaired elderly people. J Alzheimers Dis. 2016;49(2):387–398.
  • Chung JK, Plitman E, Nakajima S, et al. Cortical amyloid β deposition and current depressive symptoms in Alzheimer disease and mild cognitive impairment. J Geriatr Psychiatry Neurol. 2016;29(3):149–159.
  • Krell-Roesch J, Lowe VJ, Neureiter J, et al. Depressive and anxiety symptoms and cortical amyloid deposition among cognitively normal elderly persons: the Mayo clinic study of aging. Int Psychogeriatr. 2018;30(2):245–251.
  • Krell-Roesch J, Vassilaki M, Mielke MM, et al. Cortical β-amyloid burden, neuropsychiatric symptoms, and cognitive status: the Mayo clinic study of aging. Transl Psychiatry. 2019;9(1):123.
  • Yasuno F, Kazui H, Morita N, et al. High amyloid-β deposition related to depressive symptoms in older individuals with normal cognition: a pilot study. Int J Geriatr Psychiatry. 2016;31(8):920–928.
  • Staab JP. Chronic subjective dizziness. Continuum (Minneap Minn). 2012;18(5 Neuro-otology):1118–1141.
  • Staab JP, Eckhardt-Henn A, Horii A, et al. Diagnostic criteria for persistent postural-perceptual dizziness (PPPD): consensus document of the committee for the classification of vestibular disorders of the B. J Vestib Res. 2017;27(4):191–208.
  • Maarsingh OR, Dros J, Schellevis FG, et al. Dizziness reported by elderly patients in family practice: prevalence, incidence, and clinical characteristics. BMC Fam Pract. 2010;11:2.
  • Kroenke K, Lucas CA, Rosenberg ML, et al. Causes of persistent dizziness. A prospective study of 100 patients in ambulatory care. Ann Intern Med. 1992;117(11):898–904.
  • Lemere CA, Masliah E. Can Alzheimer disease be prevented by amyloid-beta immunotherapy? Nat Rev Neurol. 2010;6(2):108–119.
  • Rodrigue KM, Kennedy KM, Park DC. Beta-amyloid deposition and the aging brain. Neuropsychol Rev. 2009;19(4):436–450.
  • Grothe MJ, Barthel H, Sepulcre J, et al.; For the Alzheimer's Disease Neuroimaging Initiative. In vivo staging of regional amyloid deposition. Neurol. 2017;89(20):2031–2038.
  • Mahoney, A EJ, Edelman S, D. Cremer P. Cognitive behavior therapy for chronic subjective dizziness: longer-term gains and predictors of disability. Am J Otolaryngol. 2013;34(2):115–120.
  • Morisod B, Mermod M, Maire R. Posturographic pattern of patients with chronic subjective dizziness before and after vestibular rehabilitation. J Vestib Res. 2018;27(5–6):305–311.
  • Staab JP. Psychiatric considerations in the management of dizzy patients. Adv Otorhinolaryngol. 2019;82:170–179.
  • Staab JP, Rohe DE, Eggers SD, et al. Anxious, introverted personality traits in patients with chronic subjective dizziness. J Psychosom Res. 2014;76(1):80–83.
  • Staab JP, Ruckenstein MJ, Solomon D, et al. Serotonin reuptake inhibitors for dizziness with psychiatric symptoms. Arch Otolaryngol Head Neck Surg. 2002;128(5):554–560.
  • Mdawar B, Ghossoub E, Khoury R. Selective serotonin reuptake inhibitors and Alzheimer’s disease. Neural Regen Res. 2020;15(1):41–46.
  • Cirrito JR, Disabato BM, Restivo JL, et al. Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans. Proc Natl Acad Sci USA. 2011;108(36):14968–14973.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.