3,590
Views
40
CrossRef citations to date
0
Altmetric
Articles

Colistin-resistance gene mcr in clinical carbapenem-resistant Enterobacteriaceae strains in China, 2014–2019

, , , , ORCID Icon, , & show all
Pages 237-245 | Received 14 Aug 2019, Accepted 12 Jan 2020, Published online: 29 Jan 2020

References

  • Logan LK, Weinstein RA. The epidemiology of carbapenem-resistant Enterobacteriaceae: the impact and evolution of a global menace. J Infect Dis. 2017;215(suppl_1):S28–S36.
  • Zhang R, Liu L, Zhou H, et al. Nationwide surveillance of clinical carbapenem-resistant Enterobacteriaceae (CRE) strains in China. EBioMedicine. 2017;19:98–106.
  • Zhang Y, Wang Q, Yin Y, et al. Epidemiology of carbapenem-resistant Enterobacteriaceae infections: report from the China CRE Network. Antimicrob Agents Chemother. 2018;62(2):e01882–17.
  • Hu F-P, Guo Y, Zhu DM, et al. Resistance trends among clinical isolates in China reported from CHINET surveillance of bacterial resistance, 2005–2014. Clin Microbiol Infect. 2016;22:S9–S14.
  • Nordmann P, Dortet L, Poirel L. Carbapenem resistance in Enterobacteriaceae: here is the storm!. Trends Mol Med. 2012;18(5):263–272.
  • Boutal H, Vogel A, Bernabeu S, et al. A multiplex lateral flow immunoassay for the rapid identification of NDM-, KPC-, IMP-and VIM-type and OXA-48-like carbapenemase-producing Enterobacteriaceae. J Antimicrob Chemother. 2018;73(4):909–915.
  • Zhang R, Chan EW-c, Zhou H, et al. Prevalence and genetic characteristics of carbapenem-resistant Enterobacteriaceae strains in China. Lancet Infect Dis. 2017;17(3):256–257.
  • van Duin D, Bonomo RA. Ceftazidime/avibactam and ceftolozane/tazobactam: second-generation β-lactam/β-lactamase inhibitor combinations. Clin Infect Dis. 2016;63(2):234–241.
  • He T, Wang R, Liu D, et al. Emergence of plasmid-mediated high-level tigecycline resistance genes in animals and humans. Nat Microbiol. 2019;4(9):1450–1456.
  • World Health Organization. Critically important antimicrobials for human medicine, 3rd revision. Geneva: WHO; 2012.
  • Giamarellou H. Epidemiology of infections caused by polymyxin-resistant pathogens. Int J Antimicrob Agents. 2016;48(6):614–621.
  • Ah Y-M, Kim A-J, Lee J-Y. Colistin resistance in Klebsiella pneumoniae. Int J Antimicrob Agents. 2014;44(1):8–15.
  • Walsh TR, Wu Y. China bans colistin as a feed additive for animals. Lancet Infect Dis. 2016;16(10):1102–1103.
  • Liu Y-Y, Wang Y, Walsh TR, et al. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study. Lancet Infect Dis. 2016;16(2):161–168.
  • Shen Y, Zhou H, Xu J, et al. Anthropogenic and environmental factors associated with high incidence of mcr-1 carriage in humans across China. Nat Microbiol. 2018;3(9):1054.
  • Wang Y, Zhang R, Li J, et al. Comprehensive resistome analysis reveals the prevalence of NDM and MCR-1 in Chinese poultry production. Nat Microbiol. 2017;2(4):16260.
  • Sun P, Bi Z, Nilsson M, et al. Occurrence of blaKPC-2, blaCTX-M, and mcr-1 in Enterobacteriaceae from well water in rural China. Antimicrob Agents Chemother. 2017;61(4):e02569–16.
  • Bocanegra-Ibarias P, Garza-González E, Morfín-Otero R, et al. Molecular and microbiological report of a hospital outbreak of NDM-1-carrying Enterobacteriaceae in Mexico. PLoS ONE. 2017;12(6):e0179651.
  • Castanheira M, Griffin MA, Deshpande LM, et al. Detection of mcr-1 among Escherichia coli clinical isolates collected worldwide as part of the SENTRY antimicrobial surveillance program during 2014-2015. Antimicrob Agents Chemother. 2016: AAC. 01267-16.
  • Dallenne C, Da Costa A, Decré D, et al. Development of a set of multiplex PCR assays for the detection of genes encoding important β-lactamases in Enterobacteriaceae. J Antimicrob Chemother. 2010;65(3):490–495.
  • Rebelo AR, Bortolaia V, Kjeldgaard JS, et al. Multiplex PCR for detection of plasmid-mediated colistin resistance determinants, mcr-1, mcr-2, mcr-3, mcr-4 and mcr-5 for surveillance purposes. Eurosurveillance. 2018;23(6): 17-00672.
  • Kieffer N, Royer G, Decousser JW, et al. mcr-9, an inducible gene encoding an acquired phosphoethanolamine transferase in Escherichia coli, and its origin. Antimicrob Agents Chemother. 2019: AAC.00965-19.
  • Clinical and L.S. Institute. Performance standards for antimicrobial testing: twenty-sixth informational supplement M100-S26. Wayne, PA: CLSI; 2016.
  • Testing E.C.o.A.S: breakpoint tables for interpretation of MICs and zone diameters. 2016, version.
  • Bolger AM, Lohse M, Usadel B. Trimmomatic: a flexible trimmer for Illumina sequence data. Bioinformatics. 2014;30(15):2114–2120.
  • Bankevich A, Nurk S, Antipov D, et al. SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing. J Comput Biol. 2012;19(5):455–477.
  • Overbeek R, Olson R, Pusch GD, et al. The SEED and the rapid annotation of microbial genomes using subsystems technology (RAST). Nucleic Acids Res. 2013;42(D1):D206–D214.
  • Zankari E, Hasman H, Cosentino S, et al. Identification of acquired antimicrobial resistance genes. J Antimicrob Chemother. 2012;67(11):2640–2644.
  • Carattoli A, Zankari E, Garcìa-Fernandez A, et al. Plasmidfinder and pMLST: in silico detection and typing of plasmids. Antimicrob Agents Chemother. 2014: AAC.02412-14.
  • Siguier P, Pérochon J, Lestrade L, et al. ISfinder: the reference centre for bacterial insertion sequences. Nucleic Acids Res. 2006;34(suppl_1):D32–D36.
  • Seemann T. Scan contig files against PubMLST typing schemes. 2016. Available from: https://github.com/tseemann/mlst.
  • Github. ECTyper. Available from: https://github.com/phac-nml/ecoli_serotyping.
  • Alikhan N-F, Li Y, Lee W, et al. BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons. BMC Genomics. 2011;12(1):1.
  • Treangen TJ, Ondov BD, Koren S, et al. The harvest suite for rapid core-genome alignment and visualization of thousands of intraspecific microbial genomes. Genome Biol. 2014;15(11):524.
  • Letunic I, Bork P. Interactive tree Of Life (iTOL) v4: recent updates and new developments. Nucleic Acids Res. 2019;47(W1):W256–W259.
  • Nezhadi J, Narenji H, Soroush Barhaghi MH, et al. Peptide nucleic acid-mediated re-sensitization of colistin resistance Escherichia coli KP81 harboring mcr-1 plasmid. Microb Pathog. 2019;135:103646.
  • Aires CAM, da Conceição-Neto OC, e Oliveira TRT, et al. Emergence of the plasmid-mediated mcr-1 gene in clinical KPC-2-producing Klebsiella pneumoniae sequence type 392 in Brazil. Antimicrob Agents Chemother. 2017;61(7):e00317–17.
  • Dalmolin TV, Castro L, Mayer FQ, et al. Co-occurrence of mcr-1 and bla KPC-2 in a clinical isolate of Escherichia coli in Brazil. J Antimicrob Chemother. 2017;72(8):2404–2406.
  • Delgado-Blas JF, Ovejero CM, Abadia-Patiño L, et al. Coexistence of mcr-1 and blaNDM-1 in Escherichia coli from Venezuela. Antimicrob Agents Chemother. 2016;60(10):6356–6358.
  • Kong L-H, Lei CW, Ma SZ, et al. Various sequence types of Escherichia coli isolates coharboring blaNDM-5 and mcr-1 genes from a commercial swine farm in China. Antimicrob Agents Chemother. 2017;61(3):e02167–16.
  • Sun J, Yang R-S, Zhang Q, et al. Co-transfer of bla NDM-5 and mcr-1 by an IncX3–X4 hybrid plasmid in Escherichia coli. Nat Microbiol. 2016;1(12):16176.
  • Quan J, Li X, Chen Y, et al. Prevalence of mcr-1 in Escherichia coli and Klebsiella pneumoniae recovered from bloodstream infections in China: a multicentre longitudinal study. Lancet Infect Dis. 2017;17(4):400–410.
  • Falagas ME, Rafailidis PI, Matthaiou DK. Resistance to polymyxins: mechanisms, frequency and treatment options. Drug Resist Updates. 2010;13(4–5):132–138.
  • Tacao M, Tavares RdS, Teixeira P, et al. mcr-1 and blaKPC-3 in Escherichia coli sequence type 744 after meropenem and colistin therapy, Portugal. Emerging Infect Dis.. 2017;23(8):1419.
  • Mediavilla JR, Patrawalla A, Chen L, et al. Colistin-and carbapenem-resistant Escherichia coli harboring mcr-1 and blaNDM-5, causing a complicated urinary tract infection in a patient from the United States. MBio. 2016;7(4):e01191–16.
  • Li X, Mu X, Zhang P, et al. Detection and characterization of a clinical Escherichia coli sT3204 strain coproducing nDM-16 and McR-1. Infect Drug Resist. 2018;11:1189.
  • Zhang Y, Liao K, Gao H, et al. Decreased fitness and virulence in ST10 Escherichia coli harboring blaNDM-5 and mcr-1 against a ST4981 strain with blaNDM-5. Front Cell Infect Microbiol. 2017;7:242.
  • Shen Z, Hu Y, Sun Q, et al. Emerging carriage of NDM-5 and MCR-1 in Escherichia coli from healthy people in multiple regions in China: a cross sectional observational study. EClinicalMedicine. 2018;6:11–20.
  • Zheng B, Yu X, Xu H, et al. Complete genome sequencing and genomic characterization of two Escherichia coli strains co-producing MCR-1 and NDM-1 from bloodstream infection. Sci Rep. 2017;7(1):17885.
  • Nguyen LP, Pinto NA, Vu TN, et al. Resistome profiles, plasmid typing, and whole-genome phylogenetic tree analyses of BlaNDM-9 and Mcr-1 Co-harboring Escherichia coli ST617 from a patient without a history of farm exposure in Korea. Pathogens. 2019;8(4):212.
  • Dong N, Zhang R, Liu L, et al. Genome analysis of clinical multilocus sequence Type 11 Klebsiella pneumoniae from China. Microb Genomics. 2018;4(2):e000149.
  • Zhang C, Feng Y, Liu F, et al. A phage-like IncY plasmid carrying the mcr-1 gene in Escherichia coli from a pig farm in China. Antimicrob Agents Chemother. 2017;61(3):e02035–16.
  • Li R, Xie M, Zhang J, et al. Genetic characterization of mcr-1-bearing plasmids to depict molecular mechanisms underlying dissemination of the colistin resistance determinant. J Antimicrob Chemother. 2016;72(2):393–401.
  • Villa L, Poirel L, Nordmann P, et al. Complete sequencing of an IncH plasmid carrying the bla NDM-1, bla CTX-M-15 and qnrB1 genes. J Antimicrob Chemother. 2012;67(7):1645–1650.
  • Carattoli A, Villa L, Poirel L, et al. Evolution of IncA/C blaCMY-2-carrying plasmids by acquisition of the blaNDM-1 carbapenemase gene. Antimicrob Agents Chemother. 2012;56(2):783–786.
  • Bonnin RA, Poirel L, Carattoli A, et al. Characterization of an IncFII plasmid encoding NDM-1 from Escherichia coli ST131. PLoS ONE. 2012;7(4):e34752.
  • Ho P-L, Li Z, Lo WU, et al. Identification and characterization of a novel incompatibility group X3 plasmid carrying bla NDM-1 in Enterobacteriaceae isolates with epidemiological links to multiple geographical areas in China. Emerg Microbes Infect. 2012;1(1):1–6.