2,432
Views
8
CrossRef citations to date
0
Altmetric
Articles

Unbalanced production of LTB4/PGE2 driven by diabetes increases susceptibility to cutaneous leishmaniasis

, , , , , , , , , , & show all
Pages 1275-1286 | Received 24 Mar 2020, Accepted 20 May 2020, Published online: 11 Jun 2020

References

  • Katsarou A, Gudbjörnsdottir S, Rawshani A, et al. Type 1 diabetes mellitus. Nat Rev Dis Prim. 2017;doi:10.1038/nrdp.2017.16.
  • Donath MY, Shoelson SE. Type 2 diabetes as an inflammatory disease. Nat Rev Immunol. 2011;11:98–107. doi: 10.1038/nri2925
  • Bowling FL, Rashid ST, Boulton AJM. Preventing and treating foot complications associated with diabetes mellitus. Nat Rev Endocrinol. 2015;11:606–616. doi: 10.1038/nrendo.2015.130
  • Ezzati M. Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010 : a comparative risk assessment. LANCET Diabetes Endocrinol. 2014;2:634–647. doi: 10.1016/S2213-8587(14)70165-2
  • Golden SH, Anderson C, Bray GA, et al. Update on Prevention of cardiovascular disease in Adults With Type 2 diabetes mellitus in light of recent Evidence : A Scienti fi c Statement from the American Heart association and the American diabetes association. Diabetes Care. 2015;38:1777–1803. doi: 10.2337/dci15-0012
  • Vincent AM, Callaghan BC, Smith AL, et al. Diabetic neuropathy: cellular mechanisms as therapeutic targets. Nat Rev Neurol. 2011;7:573–583. doi: 10.1038/nrneurol.2011.137
  • Wu Y, Quan Y, Liu Y, et al. Hyperglycaemia inhibits REG3A expression to exacerbate TLR3-mediated skin inflammation in diabetes. Nat Commun. 2016;7:13393. doi: 10.1038/ncomms13393
  • Federation ID. IDF Diabetes Atlas - 2019. 2019 doi:10.1289/image.ehp.v119.i03.
  • World Health Organization. Estimates for the year 2000 and projections for 2030. World Health. 2004;27:1047–1053.
  • Chiheb S, Oudrhiri L, Zouhair K, et al. Unusual clinical presentation of cutaneous leishmaniasis in three diabetic patients | Leishmanioses cutanées d’aspect clinique inhabituel chez trois patients diabétiques. Ann Dermatol Venereol. 2012;139:542–545. doi: 10.1016/j.annder.2012.05.013
  • Join-Lambert O, Fraitag S, Ribadeau-Dumas F, et al. Is granulomatous mastitis a localized form of hidradenitis suppurativa? Eur J Dermatology. 2009;19:513–514. doi: 10.1684/ejd.2009.0731
  • Kono H, Onda A, Yanagida T. Molecular determinants of sterile inflammation. Curr Opin Immunol. 2014;26:147–156. doi: 10.1016/j.coi.2013.12.004
  • Filgueiras LR, Brandt SL, Wang S, et al. Leukotriene B 4 -mediated sterile inflammation favors susceptibility to sepsis in murine type 1 diabetes HHS Public Access. Sci Signal. 2015;8, doi:10.1126/scisignal.2005568.
  • Ramalho T, Filgueiras L, Silva-Jr IA, et al. Impaired wound healing in type 1 diabetes is dependent on 5-lipoxygenase products. Sci Rep. 2018;8:14164. doi: 10.1038/s41598-018-32589-7
  • Brandt SL, Wang S, Dejani NN, et al. Excessive localized leukotriene B4 levels dictate poor skin host defense in diabetic mice. J Clin Invest. 2018;3(17):1–16.
  • Maspi N, Abdoli A, Ghaffarifar F. Pro- and anti-inflammatory cytokines in cutaneous leishmaniasis: a review. Pathog Glob Health. 2016;110:247–260. doi: 10.1080/20477724.2016.1232042
  • Saldanha MG, Queiroz A, Machado PRL, et al. Characterization of the histopathologic features in patients in the early and late phases of cutaneous leishmaniasis. Am J Trop Med Hyg. 2017;96:645–652.
  • Morato CI, da Silva IA, Borges AF, et al. Essential role of leukotriene B4 on Leishmania (Viannia) braziliensis killing by human macrophages. Microbes Infect. 2014; doi:10.1016/j.micinf.2014.08.015.
  • Tavares N, Afonso L, Suarez M, et al. Degranulating neutrophils promote leukotriene B 4 production by infected macrophages To Kill Leishmania amazonensis parasites. J Immunol. 2016;196:1865–1873. doi: 10.4049/jimmunol.1502224
  • Araújo-Santos T, Prates DB, França-Costa J, et al. Prostaglandin E 2/leukotriene B 4 balance induced by Lutzomyia longipalpis saliva favors Leishmania infantum infection. Parasites and Vectors. 2014;7:1–8. doi: 10.1186/s13071-014-0601-8
  • Chaves MM, Marques-da-Silva C, Monteiro APT, et al. Leukotriene B4 Modulates P2X7 receptor-mediated Leishmania amazonensis elimination in Murine macrophages. J Immunol. 2014;192:4765–4773. doi: 10.4049/jimmunol.1301058
  • Peters-golden M, Henderson WR. Leukotrienes. N Engl J Med. 2007;357:1841–1854. doi: 10.1056/NEJMra071371
  • Ricciotti E, Fitzgerald AG. [Eicosanoid neuroinflammation] prostaglandins and inflammation. Arter Thromb Vasc Biol. 2011;31:986–1000. doi: 10.1161/ATVBAHA.110.207449
  • Serezani CH, Lewis C, Jancar S, et al. Leukotriene B4 amplifies NF-??B activation in mouse macrophages by reducing SOCS1 inhibition of MyD88 expression. J Clin Invest. 2011. doi:10.1172/JCI43302.
  • Afonso P V, Janka-Junttila M, Lee YJ, et al. LTB4 is a signal-Relay Molecule during neutrophil chemotaxis. Dev Cell. 2012;22:1079–1091. doi: 10.1016/j.devcel.2012.02.003
  • Brandt SL, Serezani CH. Too much of a good thing: How modulating LTB 4 actions restore host defense in homeostasis or disease. Semin Immunol. 2017;33:37–43. doi: 10.1016/j.smim.2017.08.006
  • Nataraj C, Thomas DW, Tilley SL, et al. Receptors for prostaglandin E2 that regulate cellular immune responses in the mouse. J Clin Invest. 2001;108:1229–1235. doi: 10.1172/JCI200113640
  • Ogawa M, Suzuki J-I, Kosuge H, et al. The mechanism of Anti-inflammatory effects of Prostaglandin E2 receptor 4 activation in Murine Cardiac Transplantation. Transplantation. 2009;87:1645–1653. doi: 10.1097/TP.0b013e3181a5c84c
  • Gill SK, Yao Y, Kay LJ, et al. The anti-inflammatory effects of PGE2 on human lung macrophages are mediated by the EP4 receptor. Br J Pharmacol. 2016;173:3099–3109. doi: 10.1111/bph.13565
  • Díaz-Gandarilla JA, Osorio-Trujillo C, Hernández-Ramírez VI, et al. PPAR activation induces m1 macrophage polarization via cPLACOX-2 inhibition, activating ros production against Leishmania Mexicana. Biomed Res Int. 2013;2013, doi:10.1155/2013/215283.
  • Amorim CF, Novais FO, Nguyen BT, et al. Variable gene expression and parasite load predict treatment outcome in cutaneous leishmaniasis. Sci Transl Med. 2019;4204:1–10.
  • Chaves MM, Canetti C, Coutinho-Silva R. Crosstalk between purinergic receptors and lipid mediators in leishmaniasis. Parasit Vectors. 2016;9:489. doi: 10.1186/s13071-016-1781-1
  • Li P, Oh DY, Bandyopadhyay G, et al. LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes. Nat Med. 2015;21:239–247. doi: 10.1038/nm.3800
  • Saiwai H, Ohkawa Y. The LTB4-BLT1 Axis Mediates neutrophil Infiltration and secondary injury in experimental Spinal Cord injury. Am J Pathol. 2010;176:2352–2366. doi: 10.2353/ajpath.2010.090839
  • Serezani CH, Lewis C, Jancar S, et al. Leukotriene B 4 amplifies NF- κ B activation in mouse macrophages by reducing SOCS1 inhibition of MyD88 expression. J Clin Invest. 2011;121:671–682. doi: 10.1172/JCI43302
  • Guimarães FR, Sales-Campos H, Nardini V, et al. The inhibition of 5-lipoxygenase (5-LO) products leukotriene B4 (LTB4) and cysteinyl leukotrienes (cysLTs) modulates the inflammatory response and improves cutaneous wound healing. Clin Immunol. 2018;190:74–83. doi: 10.1016/j.clim.2017.08.022
  • Simpson DM, Ross R. The neutrophilic leukocyte in wound repair a study with antineutrophil serum. J Clin Invest. 1972;51:2009–2023. doi: 10.1172/JCI107007
  • McDonald B, Kubes P. Chemokines: Sirens of neutrophil recruitment-but Is It Just One Song? Immunity. 2010;33:148–149. doi: 10.1016/j.immuni.2010.08.006
  • Benfield T, Jensen JS, Nordestgaard BG. Influence of diabetes and hyperglycaemia on infectious disease hospitalisation and outcome. Diabetologia. 2007;50:549–554. doi: 10.1007/s00125-006-0570-3
  • Alves C, Casqueiro J, Casqueiro J. Infections in patients with diabetes mellitus: A review of pathogenesis. Indian J Endocrinol Metab. 2012;16:27. doi: 10.4103/2230-8210.94253
  • Neto AF, Dell’Armelina Rocha PR, Perez EC, et al. Diabetes mellitus increases the susceptibility to encephalitozoonosis in mice. PLoS One. 2017;12:1–18. doi: 10.1371/journal.pone.0181612
  • Robbins GR, Wen H, Ting JPY. Inflammasomes and metabolic disorders: Old genes in modern diseases. Mol Cell. 2014;54:297–308. doi: 10.1016/j.molcel.2014.03.029
  • Lakhani CM. Toll-Like receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in mice. Physiol Behav. 2019;176:139–148.
  • Wen H, Gris D, Lei Y, et al. Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nat Immunol. 2011;12:408–415. doi: 10.1038/ni.2022
  • Thiem K, Stienstra R, Riksen NP, et al. Trained immunity and diabetic vascular disease. Clin Sci. 2019;133:195–203. doi: 10.1042/CS20180905
  • Filgueiras LR, Brandt SL, Wang S, et al. Leukotriene B 4 – mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes. Sci Signal. 2015;8:1–10. doi: 10.1126/scisignal.2005568
  • Boizel R, Bruttmann G, Benhamou PY, et al. Regulation of oxidative stress and inflammation by glycaemic control: Evidence for reversible activation of the 5-lipoxygenase pathway in type 1, but not in type 2 diabetes. Diabetologia. 2010;53:2068–2070. doi: 10.1007/s00125-010-1822-9
  • Novais FO, Nguyen BT, Beiting DP, et al. Human Classical monocytes control the intracellular Stage of Leishmania braziliensis by reactive oxygen species. J Infect Dis 2014;209, doi:10.1093/infdis/jiu013.
  • Chao WC, Yen CL, Wu YH, et al. Increased resistin may suppress reactive oxygen species production and inflammasome activation in type 2 diabetic patients with pulmonary tuberculosis infection. Microbes Infect. 2015;17:195–204. doi: 10.1016/j.micinf.2014.11.009
  • Zheng LX, Li KX, Hong FF, et al. Pain and bone damage in rheumatoid arthritis: role of leukotriene B4. Clin Exp Rheumatol 2019;37:872–878.
  • Geng S, Zhang Y, Lee C, et al. Novel reprogramming of neutrophils modulates inflammation resolution during atherosclerosis. Sci Adv. 2019;5, doi:10.1126/sciadv.aav2309.