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Emerging Microbes & Infections Volume 11, 2022 - Issue 1
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Coronaviruses

The prominent role of a CDR1 somatic hypermutation for convergent IGHV3-53/3-66 antibodies in binding to SARS-CoV-2

Xiaolong Tiana MOE/NHC Key Laboratory of Medical Molecular Virology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People’s Republic of ChinaView further author information
,
Xiaoyi Zhua MOE/NHC Key Laboratory of Medical Molecular Virology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People’s Republic of ChinaView further author information
,
Wenping Songa MOE/NHC Key Laboratory of Medical Molecular Virology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People’s Republic of ChinaView further author information
,
Zhenlin Yangb Shanghai Engineering Research Center for Synthetic Immunology, Shanghai, People’s Republic of China;c Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China;d Shanghai Key Laboratory of Lung Inflammation and Injury, Shanghai, People’s Republic of ChinaView further author information
,
Yanling Wua MOE/NHC Key Laboratory of Medical Molecular Virology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People’s Republic of China;b Shanghai Engineering Research Center for Synthetic Immunology, Shanghai, People’s Republic of ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-8780-8640View further author information
ORCID Icon &
Tianlei Yinga MOE/NHC Key Laboratory of Medical Molecular Virology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People’s Republic of China;b Shanghai Engineering Research Center for Synthetic Immunology, Shanghai, People’s Republic of China;d Shanghai Key Laboratory of Lung Inflammation and Injury, Shanghai, People’s Republic of ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-9597-2843View further author information
ORCID Icon
Pages 1186-1190 | Received 22 Dec 2021, Accepted 03 Apr 2022, Published online: 25 Apr 2022

References

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  • Kitaura K, et al. Different somatic hypermutation levels among antibody subclasses disclosed by a New next-generation sequencing-based antibody repertoire analysis. Front Immunol. 2017;8(389).
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