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Emerging Microbes & Infections Volume 11, 2022 - Issue 1
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Letter

Viral RNA and infectious virus in mucosal specimens from guinea pigs modelling early phases of lethal and non-lethal Lassa fever

Stephen R. WelchViral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USAORCID Iconhttps://orcid.org/0000-0002-6905-8521View further author information
ORCID Icon,
Sarah C. GenzerViral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USAView further author information
,
JoAnn D. Coleman-McCrayViral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USAView further author information
,
Jessica R. HarmonViral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USAView further author information
,
Florine E.M. ScholteViral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USAORCID Iconhttps://orcid.org/0000-0003-2110-3087View further author information
ORCID Icon,
Joel M. MontgomeryViral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USAView further author information
,
Christina F. SpiropoulouViral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USAORCID Iconhttps://orcid.org/0000-0001-8406-3161View further author information
ORCID Icon &
Jessica R. SpenglerViral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USACorrespondence[email protected]
[email protected]
ORCID Iconhttps://orcid.org/0000-0002-5383-0513View further author information
ORCID Icon show all
Pages 1390-1393 | Received 22 Feb 2022, Accepted 25 Apr 2022, Published online: 23 May 2022

References

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  • Spengler JR, Kainulainen MH, Welch SR, et al. Lassa virus replicon particle vaccine protects strain 13/N Guinea pigs against challenge with geographically and genetically diverse viral strains. J Infect Dis. 2022. doi:10.1093/infdis/jiac028
  • Albariño CG, Bird BH, Chakrabarti AK, et al. Efficient rescue of recombinant Lassa virus reveals the influence of S segment noncoding regions on virus replication and virulence. J Virol. 2011 Apr;85(8):4020–4024.
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  • Spengler JR, Chakrabarti AK, Coleman-McCray JD, et al. Utility of oral swab sampling for Ebola virus detection in Guinea pig model. Emerg Infect Dis. 2015 Oct;21(10):1816–1819.
  • Wozniak DM, Riesle-Sbarbaro SA, Kirchoff N, et al. Inoculation route-dependent Lassa virus dissemination and shedding dynamics in the natural reservoir – Mastomys natalensis. Emerg Microbes Infect. 2021 Dec;10(1):2313–2325.

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