2,152
Views
0
CrossRef citations to date
0
Altmetric
Zika

Identification and characterization of key residues in Zika virus envelope protein for virus assembly and entry

, & ORCID Icon
Pages 1604-1620 | Received 16 Mar 2022, Accepted 23 May 2022, Published online: 10 Jun 2022

References

  • Gould EA, Solomon T. Pathogenic flaviviruses. Lancet. 2008 Feb 9;371(9611):500–509.
  • Dick GW, Kitchen SF, Haddow AJ, et al. Isolations and serological specificity. Trans R Soc Trop Med Hyg. 1952 Sep;46(5):509–520.
  • Saiz JC, Vázquez-Calvo Á, Blázquez AB, et al. Zika virus: the latest newcomer. Front Microbiol. 2016;7:496.
  • Musso D, Ko AI, Baud D. Zika virus infection – after the pandemic. N Engl J Med. 2019 Oct 10;381(15):1444–1457.
  • Lindenbach BD, Thiel H-J, Rice CM. Flaviviridae: the viruses and their relication. In Knipe DM, Howley PM, (eds.), Fields virology, 5th ed. Philadelphia: Lippincott, Williams & Wilkins; 2007Jan 01:1101–1152.
  • Lindenbach BD. Virion assembly and release. Curr Top Microbiol Immunol. 2013;369:199–218.
  • Xie X, Yang Y, Muruato AE, et al. Understanding Zika virus stability and developing a chimeric vaccine through functional analysis. mBio. 2017 Feb 7;8:1.
  • Shang Z, Song H, Shi Y, et al. Crystal structure of the capsid protein from Zika virus. J Mol Biol. 2018 Mar 30;430(7):948–962.
  • Yu IM, Zhang W, Holdaway HA, et al. Structure of the immature dengue virus at low pH primes proteolytic maturation. Science. 2008 Mar 28;319(5871):1834–1837.
  • Lorenz IC, Allison SL, Heinz FX, et al. Folding and dimerization of tick-borne encephalitis virus envelope proteins prM and E in the endoplasmic reticulum. J Virol. 2002 Jun;76(11):5480–5491.
  • Heinz FX, Stiasny K. The antigenic structure of Zika virus and its relation to other flaviviruses: implications for infection and immunoprophylaxis. Microbiol Mol Biol Rev. 2017 Mar;81:1.
  • Hasan SS, Sevvana M, Kuhn RJ, et al. Structural biology of Zika virus and other flaviviruses. Nat Struct Mol Biol. 2018 Jan;25(1):13–20.
  • Rey FA, Stiasny K, Heinz FX. Flavivirus structural heterogeneity: implications for cell entry. Curr Opin Virol. 2017 Jun;24:132–139.
  • Smit JM, Moesker B, Rodenhuis-Zybert I, et al. Flavivirus cell entry and membrane fusion. Viruses. 2011 Feb;3(2):160–171.
  • Hamel R, Dejarnac O, Wichit S, et al. Biology of Zika virus infection in human skin cells. J Virol. 2015 Sep;89(17):8880–8896.
  • Nowakowski TJ, Pollen AA, Di Lullo E, et al. Expression analysis highlights AXL as a candidate Zika virus entry receptor in neural stem cells. Cell Stem Cell. 2016 May 5;18(5):591–596.
  • Zhu Z, Mesci P, Bernatchez JA, et al. Zika virus targets glioblastoma stem cells through a SOX2-integrin α(v)β(5) axis. Cell Stem Cell. 2020 Feb 6;26(2):187–204. e10.
  • Carbaugh DL, Baric RS, Lazear HM. Envelope protein glycosylation mediates Zika virus pathogenesis. J Virol. 2019 Jun 15;93:12.
  • Prado Acosta M, Geoghegan EM, Lepenies B, et al. Surface (S) layer proteins of Lactobacillus acidophilus block virus infection via DC-SIGN interaction. Front Microbiol. 2019;10:810.
  • Routhu NK, Lehoux SD, Rouse EA, et al. Glycosylation of Zika virus is important in host-virus interaction and pathogenic potential. Int J Mol Sci. 2019 Oct 21;20:20.
  • Perera-Lecoin M, Meertens L, Carnec X, et al. Flavivirus entry receptors: an update. Viruses. 2013 Dec 30;6(1):69–88.
  • Hu T, Wu Z, Wu S, et al. The key amino acids of E protein involved in early flavivirus infection: viral entry. Virol J. 2021 Jul 3;18(1):136.
  • Rieder CA, Rieder J, Sannajust S, et al. A novel mechanism for Zika virus host-cell binding. Viruses. 2019 Nov 28;11:12.
  • Giraldo MI, Xia H, Aguilera-Aguirre L, et al. Envelope protein ubiquitination drives entry and pathogenesis of Zika virus. Nature. 2020 Sep;585(7825):414–419.
  • Roehrig JT. Antigenic structure of flavivirus proteins. Adv Virus Res. 2003;59:141–175.
  • Mukhopadhyay S, Kuhn RJ, Rossmann MG. A structural perspective of the flavivirus life cycle. Nat Rev Microbiol. 2005 Jan;3(1):13–22.
  • Chu JJH, Rajamanonmani R, Li J, et al. Inhibition of West Nile virus entry by using a recombinant domain III from the envelope glycoprotein. J Gen Virol. 2005 Feb;86(Pt 2):405–412.
  • Lee JW, Chu JJ, Ng ML. Quantifying the specific binding between West Nile virus envelope domain III protein and the cellular receptor alphaVbeta3 integrin. J Biol Chem. 2006 Jan 20;281(3):1352–1360.
  • Huerta V, Chinea G, Fleitas N, et al. Characterization of the interaction of domain III of the envelope protein of dengue virus with putative receptors from CHO cells. Virus Res. 2008 Nov;137(2):225–234.
  • Shi Y, Gao GF. Structural Biology of the Zika virus. Trends Biochem Sci. 2017 Jun;42(6):443–456.
  • Agrelli A, de Moura RR, Crovella S, et al. ZIKA virus entry mechanisms in human cells. Infect Genet Evol. 2019 Apr;69:22–29.
  • Crill WD, Roehrig JT. Monoclonal antibodies that bind to domain III of dengue virus E glycoprotein are the most efficient blockers of virus adsorption to Vero cells. J Virol. 2001 Aug;75(16):7769–7773.
  • Zhao H, Xu L, Bombardi R, et al. Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge. J Exp Med. 2020 Feb 3;217:2.
  • Nybakken GE, Oliphant T, Johnson S, et al. Structural basis of West Nile virus neutralization by a therapeutic antibody. Nature. 2005 Sep 29;437(7059):764–769.
  • Dowd KA, Pierson TC. Antibody-mediated neutralization of flaviviruses: a reductionist view. Virology. 2011 Mar 15;411(2):306–315.
  • Chambers MT, Schwarz MC, Sourisseau M, et al. Probing Zika virus neutralization determinants with glycoprotein mutants bearing linear epitope insertions. J Virol. 2018 Sep 15;92:18.
  • Shu J, Ma X, Zhang Y, et al. NS5-independent ablation of STAT2 by Zika virus to antagonize interferon signaling. Emerg Microbes Infect. 2021 Dec;10(1):1609–1625.
  • Zhang Y, Chen S, Yuan Z, et al. Bioorthogonal dissection of the replicase assembly of hepatitis C virus. Cell Chem Biol. 2021 Sep 16;28(9):1366–1378.e4.
  • Bolte S, Cordelières FP. A guided tour into subcellular colocalization analysis in light microscopy. J Microsc. 2006 Dec;224(Pt 3):213–232.
  • Hsieh SC, Zou G, Tsai WY, et al. The C-terminal helical domain of dengue virus precursor membrane protein is involved in virus assembly and entry. Virology. 2011 Feb 5;410(1):170–180.
  • Sourisseau M, Lawrence DJP, Schwarz MC, et al. Deep mutational scanning comprehensively maps how Zika envelope protein mutations affect viral growth and antibody escape. J Virol. 2019 Dec 1;93:23.
  • Scholle F, Girard YA, Zhao Q, et al. Trans-packaged West Nile virus-like particles: infectious properties in vitro and in infected mosquito vectors. J Virol. 2004 Nov;78(21):11605–11614.
  • Patkar CG, Jones CT, Chang Y, et al. Functional requirements of the yellow fever virus capsid protein. J Virol. 2007;81(12):6471–6481.
  • Steinmann E, Brohm C, Kallis S, et al. Efficient trans-encapsidation of hepatitis C virus RNAs into infectious virus-like particles. J Virol. 2008 Jul;82(14):7034–7046.
  • Patkar CG, Jones CT, Chang YH, et al. Functional requirements of the yellow fever virus capsid protein. J Virol. 2007 Jun;81(12):6471–6481.
  • Garg H, Sedano M, Plata G, et al. Development of virus-like-particle vaccine and reporter assay for Zika virus. J Virol. 2017 Oct 15;91:20.
  • Jones CT, Patkar CG, Kuhn RJ. Construction and applications of yellow fever virus replicons. Virology. 2005 Jan 20;331(2):247–259.
  • Scull MA, Schneider WM, Flatley BR, et al. The N-terminal helical region of the hepatitis C virus p7 ion channel protein is critical for infectious virus production. PLoS Pathog. 2015 Nov;11(11):e1005297.
  • Lee E, Stocks CE, Amberg SM, et al. Mutagenesis of the signal sequence of yellow fever virus prM protein: enhancement of signalase cleavage in vitro is lethal for virus production. J Virol. 2000 Jan;74(1):24–32.
  • Li G, Bos S, Tsetsarkin KA, et al. The roles of prM-E proteins in historical and epidemic Zika virus-mediated infection and neurocytotoxicity. Viruses. 2019 Feb 14;11:2.
  • Nambala P, Yu WY, Lo YC, et al. Ubiquitination of Zika virus precursor membrane protein promotes the release of viral proteins. Virus Res. 2020 Sep;286:198065.
  • Yuan L, Huang XY, Liu ZY, et al. A single mutation in the prM protein of Zika virus contributes to fetal microcephaly. Science. 2017 Nov 17;358(6365):933–936.
  • Renner M, Dejnirattisai W, Carrique L, et al. Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins. Nat Commun. 2021 Feb 23;12(1):1238.
  • Naganathan S, Grunbeck A, Tian H, et al. Genetically-encoded molecular probes to study G protein-coupled receptors. J Vis Exp. 2013 Sep 13;1:79.
  • Tan TY, Fibriansah G, Kostyuchenko VA, et al. Capsid protein structure in Zika virus reveals the flavivirus assembly process. Nat Commun. 2020 Feb 14;11(1):895.
  • Kostyuchenko VA, Lim EX, Zhang S, et al. Structure of the thermally stable Zika virus. Nature. 2016 May 19;533(7603):425–428.
  • Prasad VM, Miller AS, Klose T, et al. Structure of the immature Zika virus at 9 A resolution. Nat Struct Mol Biol. 2017 Feb;24(2):184–186.
  • Dowd KA, Pierson TC. The many faces of a dynamic virion: implications of viral breathing on flavivirus biology and immunogenicity. Annu Rev Virol. 2018 Sep 29;5(1):185–207.
  • Butrapet S, Childers T, Moss KJ, et al. Amino acid changes within the E protein hinge region that affect dengue virus type 2 infectivity and fusion. Virology. 2011 Apr 25;413(1):118–127.
  • Kaufmann B, Rossmann MG. Molecular mechanisms involved in the early steps of flavivirus cell entry. Microbes Infect. 2011 Jan;13(1):1–9.